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338 articles for “Cancer Cell”
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Advancing Cancer Vaccine Development through CRISPR/Cas9 Technologies and Future Opportunities
Abstract: The advent of CRISPR/Cas9 genome editing has revolutionized the cancer immunotherapy market, offering unprecedented precision and versatility in the development of next-generation cancer vaccines. This review examines how CRISPR technologies are being integrated into various stages of cancer vaccine development including neoantigen discovery, dendritic cell engineering, cancer cell reprogramming, and tumor microenvironment modulation. In the area of neoantigen discovery, CRISPR enables rapid identification and validation of tumor-specific mutations, thereby supporting …
Published in International Journal of Vaccines · Vol. 2, Issue 2, 2025 Read article
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A Review on Unmasking Merkel Cell Polyomavirus: From Discovery to Cancer Driver
Abstract: Merkel cell polyomavirus (MCPyV) is a small, non-enveloped, circular double-stranded DNA virus belonging to the Polyomaviridae family, first characterized in 2008. Epidemiological data suggest widespread exposure, with seroprevalence rates approaching 80% in adults. While primary infection is typically asymptomatic, rare integration events in Merkel cells can initiate oncogenesis, yielding Merkel cell carcinoma (MCC), a neuroendocrine skin cancer with a five-year survival rate under 60%. This review integrates findings from six …
Published in International Journal of Virus Studies · Vol. 2, Issue 2, 2025 · pp. 6–11 Read article
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Insilico Approach to Inhibit Over Expression of CaSm Gene to Arrest Over Expressed Human LSm1 Protein in Pancreatic Carcinoma Cell
Abstract: Small nuclear ribonucleoproteins (snRNPs) are particles that are found in the nucleus of eukaryotic cells. They consist of one RNA (snRNA) associated with one or more proteins. snRNPs are involved in a wide variety of functions including pre-mRNA splicing (e.g., U1, U2, U4–6, U11, U12, U4ATAC, U6ATAC snRNPs and transspliced leader RNPs), histone mRNA 39 end processing (U7 snRNP). The snRNA U6 (unlike U1, U2, U4 and U5) does not …
Published in Research & Reviews: A Journal of Bioinformatics · Vol. 1, Issue 3, 2014 · pp. 12–23 Read article
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Advanced Laser Technology for Curing Cancer Affected Melanoma-Cell
Abstract: In this paper we report the results about the study and experimental usage of a cancer curing laser equipment. Cancer can be detected using laser induced ultrasound .This device could scan a lymph node biopsy with laser pulses, whereby the pigment of melanin which is present in each and every cells reacts to the laser's beam, absorbing the light, and heating and cooling rapidly. This produces a popping sound that's …
Published in Journal of Electronic Design Technology · Vol. 3, Issue 1-3, 2012 · pp. 1–5 Read article
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Differential Response by Rotenone on Human Trabecular Meshwork and HeLa Cell Lines
Abstract: Cellular response towards a particular stress condition is dependent on a number of factors including genetic makeup, microenvironmental factors, nutrient availability etc. Cells under same stress condition respond differentially and may exhibit pro-apoptotic or anti-apoptotic behavior. Two quite different cell lines—the cancerous cells of HeLa and the Human Trabecular Meshwork (HTM) cell line with very different microenvironmental requirements behave very differently towards oxidative insult due to rotenone. Study of their …
Published in Research and Reviews: A Journal of Toxicology · Vol. 5, Issue 2, 2015 · pp. 14–22 Read article
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Liquid Biopsy in Solid Tumor: An Ultimate Source for Molecular Landscaping, Biomarker Discovery and Clinical Management
Abstract: Presently, work in the liquid biopsy field showed a great prospect utility in the diagnosis and stratification of cancer patients and furthermore personify an adaptive method for monitoring treatment response when compared to the tissue biopsy approach. Analysis of cell free DNA (cfDNA), circulating tumor cells (CTCs) and exosomes, all conjointly referred to as “liquid biopsies,” are not only a modality to monitor treatment efficacy, disease progression, and emerging therapy …
Published in Research and Reviews: Journal of Oncology and Hematology · Vol. 8, Issue 3, 2019 · pp. 25–36 Read article
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A Study of New Form of Antitumor Chemotherapeutic Drugs Production
Abstract: Chemotherapy methods that exist today do not permit to act with purpose on a malignant tumor with a pre-calculated shock dose of cytostatic while killing healthy cells of the human body that makes the use of these methods for the treatment of cancer patients not effective. This study presents a new type of antitumor drug obtained by a specially developed method, which is a support material with a uniform distribution …
Published in Research & Reviews: A Journal of Drug Formulation, Development and Production · Vol. 7, Issue 1, 2020 · pp. 6–10 Read article
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Recent Development Technique in Management of Cancer
Abstract: Cancer develops when a change in one's genetic makeup leads to the development of tumour cells. These clusters of malignant cells eventually develop into tumours. Tumours can shed cancerous cells, which can then travel through the lymphatic system or the circulatory system to other organs. In the medical field, this occurrence is referred to as metastasis. Cancer cells proliferate even when they have no instructions to do so. Despite the …
Published in Research and Reviews: Journal of Oncology and Hematology · Vol. 13, Issue 1, 2024 · pp. 25–41 Read article
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Uncontrolled Cell Growth and Human Health: A Comprehensive Exploration of Cancer
Abstract: Cancer is a diverse category of diseases defined by the uncontrolled proliferation and spread of aberrant cells. It remains the major cause of morbidity and mortality worldwide. This article presents an overview of the various forms of cancer, such as carcinomas, sarcomas, lymphomas, and leukaemia, emphasising their distinct causes, symptoms, and risks. Early detection and diagnosis are emphasized as key to enhancing treatment outcomes. The article further provides an in-depth …
Published in Research and Reviews: Journal of Oncology and Hematology · Vol. 15, Issue 1, 2026 · pp. 1–23 Read article
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Tiny Titans: The Promise of E-Nanorobots in the Fight Against Cancer
Abstract: Cancer, a disease characterized by uncontrolled cell growth, continues to be a leading cause of mortality worldwide. Despite advances in surgery, radiation, and chemotherapy, significant challenges remain in achieving targeted and effective treatments without harmful side effects. But what if we could deploy microscopic robots, engineered at the nanoscale, to precisely target and destroy cancerous cells while leaving healthy tissue untouched. The fascinating possibilities of e-nanorobots are driving extensive research …
Published in Journal of Advancements in Robotics · Vol. 12, Issue 2, 2025 · pp. 11–21 Read article
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Oxidative stress analysis of cancer patient treated with Radiotherapy
Abstract: Oxidative stress is a term given to overload of free radicals in the body caused by an imbalance between levels of free radicals and antioxidants in the body. Reactive Oxygen Species (ROS) are free radicals also known as oxygen radicals that are produced by various physiological reactions inside the body leading to increasing oxidative stress that can lead to cell death. In case of cancer management, radiation therapy works by …
Published in Trends in Drug Delivery · Vol. 10, Issue 1, 2023 · pp. 28–31 Read article
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Chemical Preparation Methods of Nano Material with their Applications
Abstract: Scientists were not satisfied with the diagnosis, exploration, injection and imaging through modern medical nanotechnology, but they were also able through this technology to activate smart microscopic bombs that target the cancer cell and detonate it, killing the cancer cells. This technology was tested on laboratory mice and achieved great success. Nanotechnology is the technology of the future, not only in the medical and therapeutic aspect, but also in everything …
Published in Journal of Petroleum Engineering & Technology · Vol. 14, Issue 2, 2024 · pp. 1–9 Read article
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Chemical Preparation Methods of Nano Material with their Applications
Abstract: Scientists were not satisfied with the diagnosis, exploration, injection and imaging through modern medical nanotechnology, but they were also able through this technology to activate smart microscopic bombs that target the cancer cell and detonate it, killing the cancer cells. This technology was tested on laboratory mice and achieved great success. Nanotechnology is the technology of the future, not only in the medical and therapeutic aspect, but also in everything …
Published in Journal of Modern Chemistry & Chemical Technology · Vol. 15, Issue 2, 2024 · pp. 1–9 Read article
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Oncology in Ayurveda: Concept and Management
Abstract: Cancer is known to mankind since long. The disease has been believed to be difficult to cure, due to uncontrolled cell division. Disease has been described in details as Arbuda in ayurvedic classics. There are four-fold treatments for Arbuda viz., Aushadha (medicinal management with medicinal herbs, polyherbal combinations and herbomineral compounds); Kshara (alkali treatment); Agni Karma; and Shastra (surgical removal of tumour). The selection of medicaments or process depends on …
Published in Research & Reviews: A Journal of Pharmacognosy · Vol. 3, Issue 3, 2016 · pp. 19–23 Read article
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Cancer Diagnosis by Functional Possibilities and its Applications
Abstract: This paper presents a diagnosis of cancer by the theory of function. Some properties are applied for the same. The injective, surjective and bijective mappings are used for curing the cancer disease. Inverse function also plays an important role. The set of possibilities of functional properties are proved as the particular map between the cancer cell and medicine is required to measurable cure. To curing cancer is primary objective of …
Published in Research and Reviews: Journal of Oncology and Hematology · Vol. 11, Issue 1, 2022 · pp. 1–4 Read article
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Papillary Thyroidcarcinoma in Rats After Administration of Platinum Compounds Daily
Abstract: Papillary thyroid carcinoma (PTC) predominantly grows in a solid growth pattern with papillary projections, composed of oncocytic cells with “Orphan annie eyes” nuclei. Cisplatin or Cis-Diammine dichloroplatinum (ii) (Cl2H6N2Pt); is a divalent, inorganic and water-soluble first successful platinum containing anticancer drug, used to treat various forms of cancers. The Carboplatin (C6H14N2O4Pt) and Oxaliplatin (C8H14N2O4Pt) are the investigational chemotherapy medicines, belonging to platinum analogue interfere as the Cisplatin with the genetic …
Published in Research and Reviews: A Journal of Medicine · Vol. 5, Issue 3, 2015 · pp. 27–31 Read article
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Epidermolysis Bullosa and Its Role in Cervical Cancer: An Overview
Abstract: Epidermolysis Bullosa is a group of uncommon genetic disorders that primarily affect the skin and mucous membranes. It is marked by severe skin fragility and the formation of blisters even after minor trauma. Traditionally, the focus of Epidermolysis Bullosa research has been on its dermatological manifestations, which include recurrent blistering, scarring, and the potential for infections due to the compromised skin barrier. However, recent advancements in Epidermolysis Bullosa research have …
Published in International Journal of Cell Biology and Cellular Functions · Vol. 2, Issue 2, 2024 · pp. 14–18 Read article
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An Evaluative Comparison of CD123 and CD66c as Biomarkers to Detect Minimal Residual Disease in B-Cell Acute Lymphoblastic Leukemia
Abstract: Background: B-cell Acute Lymphoblastic Leukemia (B-ALL) often shows lineage heterogeneity with lymphoid cells expressing myeloid markers. Minimal Residual Disease (MRD) refers to the small number of cancer cells that may remain in a patient's body after treatment and that are undetectable by standard diagnostic methods. In diseases like B-cell Acute Lymphoblastic Leukemia (B-ALL), MRD is a critical prognostic indicator, as its presence can signal a higher risk of relapse. In …
Published in Research and Reviews : A Journal of Medical Science and Technology · Vol. 13, Issue 3, 2024 · pp. 7–12 Read article
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The Role of Cholesterol in Biological Membranes
Abstract: Cholesterol plays the role of a regulator that ensures the correct packaging of the lipid part of the membrane, which is necessary for its normal operation, by influencing on the mobility of the fatty acid tails of membrane lipids: if the membrane is too rigid and there is a danger of "freezing" of fatty acid chains, cholesterol causes it to liquefy, since the chains in its presence become more mobile; …
Published in International Journal of Cell Biology and Cellular Functions · Vol. 1, Issue 1, 2023 · pp. 1–15 Read article
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Evaluation of Antioxidant and Cytotoxic activities of Mycelia Biomass and Culture broth of three Edible Mushrooms, Morchella conica, Hericium erinaceus and Pleurotus florida Grown in Submerged Culture
Abstract: Mycelia biomass of three edible mushrooms namely, Morchella conica, Pleurotus florida and Hericium erinaceus were grown as submerged culture in potato dextrose broth supplemented with yeast extract, potassium dihydrogen orthophosphate and magnesium sulphate. The mycelia biomass was extracted with 70% ethanol and culture broth with ethyl acetate. The solvents were evaporated to dryness at low temperature using a rotary vacuum evaporator and the residues thus obtained were used for the …
Published in International Journal of Fungi · Vol. 1, Issue 1, 2024 · pp. 37–50 Read article