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116 articles for “Anti-viral”
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Molecular Docking-Based Analysis of Rauvolfia serpentina Alkaloids Targeting HPV E1 and L1 Proteins for Antiviral Therapeutic Potential
Abstract: Human papillomavirus (HPV) is a major cause of cervical cancer and other epithelial cancers. E1 and L1 proteins are crucial to the virus's lifespan. E1 is a viral helicase that is needed for HPV DNA replication, and L1 is the main structural capsid protein that builds the virion and infects target cells. Going after these proteins is a good way to stop viruses from spreading. In this case, Rauvolfia serpentina, …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 17, Issue 1, 2026 · pp. 100–113 Read article
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In vitro Antiviral Chemical Treatment to BBTV-Infected Banana Cultures for Production of Virus-Free Plants
Abstract: Obtaining healthy plants from infected germplasm banana stocks is a major problem. Banana bunchy top virus (BBTV) is the most destructive pathogen for the banana crop. Production of virus-free plants is crucial for cultivation, germplasm conservation and their exchanges. In vitro shoot meristem culture is the most common method for producing disease-free planting material. However, BBTV can multiply with in vitro cultures too. Therefore, for eliminating BBTV, the shoot-tip culture …
Published in Research and Reviews : A Journal of Life Sciences · Vol. 9, Issue 3, 2019 · pp. 28–33 Read article
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Development and Performance Evaluation of a Polyethersulfone–Graphene Oxide Ultrafiltration Membrane for Simultaneous Drug Delivery and Virus Removal: An Experimental Investigation
Abstract: The development of multifunctional ultrafiltration membranes for simultaneous controlled drug delivery and viral removal has gained considerable attention in biomedical engineering, pharmaceutical sciences, and water purification. Polyethersulfone (PES) membranes offer excellent thermal, chemical, and mechanical stability; however, their hydrophobicity can limit permeability, antifouling performance, and biocompatibility. This study proposes the fabrication of PES–graphene oxide (GO) ultrafiltration membranes using the phase inversion technique, with systematic variation of GO concentration to optimize …
Published in International Journal of Membranes · Vol. 3, Issue 2, 2026 Read article
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A Critical Review Study of Prakriti Vighata Chikitsa in Management of Chronic Infection of Alimentary Tract Annavaha Srotas with Special Reference to Role of Sudarshana Churna in Management of Viral B Hepatitis
Abstract: AbstractKrimi refers to all types of infectious agents – microscopic or macroscopic. These agents produce diseases in the body. Ayurvedic scholars described three treatment modalities for them. Prakriti Vighata is one of them and is a unique approach of Ayurveda for the treatment of chronic infections. Prakrti Vighata management refers to changing the histopathological atmosphere in such a manner that is not favorable to the growth and development of Krimi. …
Published in Journal of AYUSH: Ayurveda, Yoga, Unani, Siddha and Homeopathy · Vol. 2, Issue 3, 2013 · pp. 1–5 Read article
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The Invisible Engineers: How Viruses Change Cells at the Molecular Level
Abstract: Viruses are frequently thought of as simple parasites, yet at the molecular level, they are quite good at engineering and may change the way the cells they infect work. The Invisible Engineers: How Viruses Rewire Cells at the Molecular Scale looks into how viruses get into host cells, mess up intracellular circuits, and exploit molecular resources to make copies of themselves. This article talks about how viral proteins and nucleic …
Published in International Journal of Virus Studies · Vol. 3, Issue 1, 2026 · pp. 1–6 Read article
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Silver Nanoparticle as Antiviral Agent and Its Uses
Abstract: Silver had been used by human thousands of years ago as various types of medicines (RasaratnaSamuccahay, Bhagbhatta). As the years passes more scientific uses of silver metals had been seen as the human civilization progresses.After the discovery of nano technology Silver is being used in a variety of ways .Nano particles exhibits less toxicity as compared to their ionic counterpart. Nowadays silver is used in various forms colloidal silver Nanoparticle …
Published in Nano Trends – A Journal of Nano Technology & Its Applications · Vol. 22, Issue 1, 2020 · pp. 28–34 Read article
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Using Multitarget Molecular Docking to Examine the Antiviral Potential of Clerodendrum Phlomidis against Measles
Abstract: Objective: Measles, a viral disease caused by a member of the Paramyxoviridae virus family, is highly contagious and characterized by a respiratory illness and a maculopapular rash on the skin. Children are the main victims of the illness. In the context of drug development, this study investigates the efficacy of phytocompounds derived from Clerodendrum phlomidis against the target protein of the measles virus. Methods: The 7SKS protein was retrieved from …
Published in International Journal of Molecular Biotechnological Research · Vol. 1, Issue 2, 2023 · pp. 32–42 Read article
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A Decade of Viral Evolution (2015–2025): Emergence, Mutations, and Implications for Global Health
Abstract: Over the past decade (2015-2025), viral evolution has profoundly reshaped the global health landscape, challenging healthcare systems, diagnostic tools, therapeutic strategies, and vaccine efficacy. This review comprehensively analyzes the evolutionary trajectories of major human and zoonotic viruses, with a focus on pandemic-prone, drug-resistant, and emerging pathogens. Viral evolution is driven by diverse molecular mechanisms including high mutation rates, recombination, reassortment, host immune pressure, and antiviral interventions, leading to genetic diversification, …
Published in International Journal of Vaccines · Vol. 2, Issue 2, 2025 · pp. 31–40 Read article
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Therapeutic and Preventive Approaches against COVID-19: A Review
Abstract: Several vaccines are found for the novel coronavirus SARS-CoV-2, responsible for the Coronavirus Disease ‘COVID-19’ but with a no clear, unified and effective treatment plan, nor definitive therapies for it, but only a variety of potential approaches. The objective of this work was to present, an overview of a variety of therapeutic and preventive approaches that have been applied instead, in a matter to calm the fatal viral pneumonia and …
Published in Research and Reviews: A Journal of Microbiology and Virology · Vol. 11, Issue 3, 2021 · pp. 26–33 Read article
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A Review on Repurposing Drugs for Treatment of Covid-19
Abstract: The newly emerged 2019 novel coronavirus is named as severe acute respiratory syndrome 2(SARS CoV-2). Till date, 1,757,393 cases have been observed in India and 37,452 deaths. COVID-19 has been now declared as pandemic and new treatments are urgently needed as we enter a phase beyond containment. In the absence of approved marketed drugs against coronavirus, the treatment and management of novel COVID-19 disease worldwide is a challenge. Developing new …
Published in Research & Reviews: A Journal of Drug Formulation, Development and Production · Vol. 7, Issue 3, 2020 · pp. 16–22 Read article
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Microorganisms used in aquaculture
Abstract: Microorganisms play a vital role in the health and sustainability of aquaculture systems, contributing to water quality management, disease control, and the overall productivity of aquatic farms. Beneficial microorganisms, including bacteria, fungi, algae, and probiotics, are increasingly recognized for their positive impact on aquaculture operations. These microorganisms can enhance nutrient cycling, promote the breakdown of organic waste, and reduce the need for harmful chemicals, thus improving the environmental footprint of …
Published in International Journal of Marine Life · Vol. 2, Issue 2, 2025 Read article
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Development of a Machine Learning and Artificial Intelligence Based Model Aimed at Forecasting the Prognostic Impact of C-Reactive Protein in Myocarditis
Abstract: The specific role of inflammation markers in myocarditis remains uncertain. We investigated the diagnostic and prognostic significance of C-reactive protein (CRP) levels at the initial diagnosis among myocarditis patients. Our retrospective study enrolled patients clinically suspected (CS) or biopsy-proven (BP) with myocarditis, with available CRP data at diagnosis. We collected patient information, including clinical, laboratory, and imaging findings at diagnosis and follow-up visits. We utilized machine learning methods, specifically random …
Published in Research and Reviews: A Journal of Health Professions · Vol. 14, Issue 2, 2024 · pp. 12–24 Read article
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In Silico Molecular Docking Studies of Phytocompounds from Melissa officinalis Against MPXV Poxin Target
Abstract: Objectives: This study aimed to evaluate the inhibitory potential of phytocompounds of Melissa officinalis against the MPXV poxin protein target, a key virulence factor in monkeypox infection. Methods: Molecular docking performed using PyRx, a virtual screening software, was conducted to predict the binding affinities of the compounds to MPXV poxin. Prior to docking, the compounds were subjected to comprehensive analysis, including Lipinski's rule of five, evaluation of physicochemical properties, pharmacological …
Published in Research and Reviews : Journal of Computational Biology · Vol. 13, Issue 2, 2024 · pp. 25–38 Read article
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Induction of Apoptosis using Gene Therapy in the Treatment of Cancer
Abstract: Gene therapy is the treatment of a genetic disease through the insertion of normal or genetically altered genes into cells in order to replace or make up for the non-functional or missing genes. A major application of gene therapy is the induction of apoptosis to inhibit metastases or cure cancer. Besides the identification of the target site, the choice of a suitable vector system for gene delivery is also critical …
Published in Research and Reviews: Journal of Oncology and Hematology · Vol. 2, Issue 3, 2013 · pp. 6–10 Read article
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Toxicological Profiling and Safety Assessment of NASAT 2.0: A Conceptual Framework for Adaptive Nanoparticle Therapy in Rabies
Abstract: Rabies, caused by the highly neurotropic Rabies lyssavirus, remains one of the most enigmatic and universally lethal infectious diseases known to modern medicine. Once clinical symptoms manifest following successful neuroinvasion, the fatality rate approaches absolute certainty (approximately 99.9%), a staggering statistic that has remained largely unchallenged despite massive, concurrent advances in modern virology, critical care medicine, and cellular immunology. Current late-stage therapeutic protocols, most notably the widely debated Milwaukee Protocol, …
Published in Research and Reviews: A Journal of Toxicology · Vol. 16, Issue 2, 2026 · pp. 1–19 Read article
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Effectiveness of Temporins for the Treatment of HPV Infections
Abstract: Objectives: Human papillomavirus (HPV), especially high-risk variants like type-16 have been linked to the formation of malignant tumors. HPV-16 has been implicated in most cases of cervical cancer in women. This study aims to assess the effectiveness of three types of temporin molecules, i.e., antiviral peptides secreted by certain frog species, for the inhibition of the viral L1 protein. Methods: In the present study, various computational tools were used to …
Published in International Journal of Cell Biology and Cellular Functions · Vol. 2, Issue 1, 2024 · pp. 41–53 Read article
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Phytotherapeutic Potential of Melaleuca: An Integrative Review of Phytochemistry and Antimicrobial, Antifungal, Antioxidant, and Antiviral Mechanisms
Abstract: Melaleuca alternifolia and other species of the Melaleuca genus stand out for the broad spectrum of pharmacological properties attributed to their bioactive compounds, such as monoterpenes, sesquiterpenes, flavonoids, and polyphenols. This study aimed to critically review and analyze scientific evidence produced between 2005 and 2025 regarding the antimicrobial, antifungal, antioxidant, and antiviral activities of Melaleuca, correlating its phytochemistry with molecular mechanisms of action. For this purpose, an integrative literature review …
Published in Research & Reviews : Journal of Herbal Science · Vol. 15, Issue 2, 2026 · pp. 16–30 Read article
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Viral Elimination Strategies for Musa spp.
Abstract: Banana is one of the major crops in tropical parts of the world. The banana plant is susceptible to many diseases due to the less genetic diversity in its popular cultivars. Particularly viral diseases can severely destruct quantity and quality of the crop. Four major banana infecting viruses doing the damage- banana bunchy top virus, banana streak virus, banana bract mosaic virus, cucumber mosaic virus; two other viruses- banana mild …
Published in Research and Reviews: A Journal of Microbiology and Virology · Vol. 8, Issue 1, 2018 · pp. 7–14 Read article
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Vaccines Through Time: Conventional Foundations and Next-Gen Innovations–Part 1
Abstract: Vaccination serves as a critical pillar of global public health, markedly decreasing infection rates and associated mortality. Traditional vaccine platforms such as live attenuated, inactivated, toxoid, and subunit vaccines have demonstrated effectiveness against pathogens like Mycobacterium tuberculosis and Plasmodium spp., yet they are constrained by antigenic variability, limited immune persistence, and complex production processes. Breakthroughs in synthetic biology, structural antigen design, and computational vaccinology have driven the development of advanced …
Published in Research and Reviews: A Journal of Microbiology and Virology · Vol. 16, Issue 1, 2026 · pp. 53–70 Read article
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A Review on Unmasking Merkel Cell Polyomavirus: From Discovery to Cancer Driver
Abstract: Merkel cell polyomavirus (MCPyV) is a small, non-enveloped, circular double-stranded DNA virus belonging to the Polyomaviridae family, first characterized in 2008. Epidemiological data suggest widespread exposure, with seroprevalence rates approaching 80% in adults. While primary infection is typically asymptomatic, rare integration events in Merkel cells can initiate oncogenesis, yielding Merkel cell carcinoma (MCC), a neuroendocrine skin cancer with a five-year survival rate under 60%. This review integrates findings from six …
Published in International Journal of Virus Studies · Vol. 2, Issue 2, 2025 · pp. 6–11 Read article