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763 articles for “drug”
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Characterization of Cellulose Producing Bacterial Isolates from Rotten Fruits
Abstract: Cellulose, the most abundant natural polymer, is predominantly sourced from plant wood but can also be synthesized by certain bacteria in the form of bio-cellulose. The potential applications of bio-cellulose are extensive, particularly in the biomedical field for tissue engineering, drug delivery, and more. The distinct properties and purity of bacterial cellulose, in contrast to plant-derived cellulose, underscore its importance and drive further research in the area. This study focuses …
Published in Research and Reviews : A Journal of Biotechnology · Vol. 14, Issue 1, 2024 · pp. 38–45 Read article
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A Research on the Additives and Regulatory Requirements for Pediatric Formulation
Abstract: These days, pediatric considerations are incorporated early on in the creation of new medications. The guidelines and policies of European drug regulatory bodies served as the foundation for our investigation. The review comprehensively outlines excipients commonly found in pediatric medicine formulations. It identifies potentially harmful compounds flagged by scientific literature, stressing the necessity of rigorous safety checks, often involving toxicity studies. Excipients included in pediatric databases, like the STEP database, …
Published in Research & Reviews: A Journal of Drug Formulation, Development and Production · Vol. 11, Issue 1, 2024 · pp. 28–45 Read article
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Underdiagnosis of Underlying Migraine in Benign Paroxysmal Positional Vertigo
Abstract: Migraine and vestibular migraine are the primary cause of headache in general population world widely. The prevalence shows that 1 in 10 people have migraine. Majorities of headache causes are undiagnosed properly and usually treated for symptomatic treatment without following correct guidelines. Standard treatment options for migraine include acute relief, lifestyle strategies, alternative remedies, and prophylactic drug. Most patients are managed in primary care using painkiller in many cases without …
Published in Research and Reviews: A Journal of Neuroscience · Vol. 14, Issue 1, 2024 · pp. 11–15 Read article
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Horizon Scanning and Early Assessment of Health Technologies for the Treatment of Orphan Diseases
Abstract: The theoretical foundations and regulatory framework of the processes of the formation of an effective health technology assessment (HTA) system at the early stages of the life cycle of medicines are analyzed in the article. Particular attention is paid to horizon scanning (HS) and early assessment of expensive innovative drugs utilized for treating rare diseases. In order to inform policymakers, purchasers, and providers (to prioritize MT research, financial, and operational …
Published in International Journal of Brain Sciences · Vol. 1, Issue 1, 2024 · pp. 32–39 Read article
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Allergic Reaction in Upper Respiratory Tract Infection (Anurjata Janya Swasa Roga) – An Ayurvedic Review and Treatment – A Case Study
Abstract: Respiratory tract infection affects the upper to lower part of the respiratory system including the nose to the alveoli of the lungs. There are two types of infections - upper respiratory infections - affecting the sinuses and throat. Upper respiratory tract infections include: common cold, epiglottitis, laryngitis, pharyngitis, and sinusitis. Lower respiratory tract infection - affects the respiratory tract and lungs. In general, lower respiratory tract infections last longer and …
Published in Research and Reviews : A Journal of Ayurvedic Science, Yoga and Naturopathy · Vol. 11, Issue 1, 2024 · pp. 26–32 Read article
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A General Review of Mucuna Pruriens W.S.R to its effect on Parkinson’s Disease.
Abstract: Mucuna Pruriens is a very famous drug prescribed in classical ayurvedic science in various disorder of Nervous System including Kampavata .In Clinical Practice ,Physician used Levadopa as a Dopamine replacement agent in controlling bradykinetic symptoms apparent in Parkinson disease so used successfully in treatment of Parkinson disease.Kapikacchu(Mucuna Pruriens) is having Balya, Brimhanaha, Vrishya, and Vatahara properties and is a natural source of L-dopa. So, keeping in views of the degenerative …
Published in Research & Reviews : Journal of Herbal Science · Vol. 13, Issue 1, 2024 · pp. 1–6 Read article
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Iron Deficiency Anaemia_A Evidence-Based Literature Review
Abstract: Iron deficiency anaemia represents a medical condition characterised by a reduction in the concentration of haemoglobin in the bloodstream below a defined level, according to the World Health Organization. The condition presents itself in two forms: functional IDA and absolute IDA. The former is characterized by normal or elevated total body iron stores, but insufficient iron supply to the bone marrow. At the same time, the latter occurs when total …
Published in Research & Reviews : Journal of Herbal Science · Vol. 13, Issue 1, 2024 · pp. 17–28 Read article
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An Open Labelled Parallel Arm Randomized Clinical Trial of Tuvaraka Oil Prepared By Two Different Method In The Management of Pama
Abstract: In Ayurveda, all skin diseases have classified mainly into two groups i.e., Mahakushtha (major skin diseases) and Kshudrakushtha (minor skin diseases). Tuvaraka [Hydnocarpus laurifolia (Dessnt).Sleumer] is one among the most useful drugs for the treatment of Kushtha (Various skin diseases) and Madhumeha (Diabetes Melitus). Pama is described under Kshudra Kushtha. which can be correlates with scabies. Aim: To evaluate the clinical efficacy of Tuvaraka oil prepared by modified method and …
Published in Research & Reviews : Journal of Herbal Science · Vol. 13, Issue 1, 2024 · pp. 29–36 Read article
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Medicinal Potential of Cullen corylifolium in Ageing and Ageing Related Diseases
Abstract: Cullen corylifolium is a tropical medicinal plant of the Fabaceae family, generally known as Babchi/Bakuchi in various regions of Asia. Cullen corylifolium is a traditional phyto-therapeutic plant of China used to manifest various pathological conditions since ages, possesing round and dark brown seeds with a rough texture. Cullen corylifolium has been previously reported to possess various properties such as antioxidant, anti-inflammatory and can be used as a solution to treat …
Published in Research & Reviews : Journal of Herbal Science · Vol. 13, Issue 2, 2024 · pp. 21–32 Read article
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Exploring Glucagon-like peptide-1 as a Target Protein for Diabetes Mellitus Treatment: Molecular Docking and Pharmacokinetic Analysis of Phytocompounds from Momordica charantia
Abstract: Objective: This study aimed to use molecular docking techniques to explore the potential of GLP-1 (glucagon-like peptide-1) as a target protein for the treatment of diabetes mellitus, a chronic metabolic disease marked by elevated blood glucose levels. Given its crucial role in maintaining insulin secretion and glucose homeostasis, GLP-1 may serve as a future target for diabetes therapy. Method: The study employed a multi-phase method. Initially, protein extraction was carried …
Published in International Journal of Biochemistry and Biomolecule Research · Vol. 2, Issue 1, 2024 · pp. 8–20 Read article
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Introduction to Biological Networks and their Contributions to Systems Biology
Abstract: Biological networks provide a conceptual framework to represent and analyze the intricate interconnections among the numerous components that make up living systems. This review paper elucidates the foundational principles of networks and their diverse applications in systems biology, highlighting their crucial role in understanding the inherent complexity of biological processes. Utilizing graph theory, these networks represent entities like genes, proteins, and metabolites as nodes, with their interactions depicted as edges. …
Published in International Journal of Bioinformatics and Computational Biology · Vol. 2, Issue 1, 2024 · pp. 53–70 Read article
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Formulation And Evaluation of Vyadhikshamatva Vardhak Giloy Ghanvatis
Abstract: The product of Kalka Kalpana, one of the five essential ayurvedic medicinal preparations, is vati Kalpana. Because of its many advantages, such as its tasty nature, ease of administration, ease of dispensing, and ease of transportation, vati kalpana is a vital part of the ayurvedic formulation. A pharmaceutical technique called vati kalpana uses powder of unprocessed medications (herbal or herbo minerals) and is triturated using juice, honey, or kassayam, and …
Published in Research & Reviews : Journal of Herbal Science · Vol. 13, Issue 2, 2024 · pp. 7–13 Read article
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Topical Luliconazole for the Management of Fungal Infections: A Review
Abstract: Luliconazole, an antifungal agent of the imidazole class, possesses a distinctive structure where the imidazole component is fused with the ketene dithioacetate configuration. It exists in its R-enantiomer form, which exhibits greater antifungal efficacy compared to lanoconazole, a compound comprising a racemic blend. Strong action is shown by luliconazole against filamentous fungi, such as dermatophytes. The pharmacokinetic characteristics of dermatophytes, such as Trichophyton rubrum and Microsporum gypseum, help explain why …
Published in Trends in Drug Delivery · Vol. 11, Issue 2, 2024 · pp. 1–6 Read article
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Heavy Metal Assessment of Rainwater from Owerri Metropolis and Suburbs of Imo State, Nigeria Using GIS, MATLAB and ANN Models.
Abstract: Three hundred and fifty (350) rainwater samples were collected from 35 select locations within Owerri Metropolis, Ehime Mbano and Mbaitoli LGAs and analyzed for Cd, Cu, Fe, Zn, and Pb using standard instrumental methods. The results were compared with the World Health Organization (WHO), National Ambient Air Quality Standards (NAAQS), Federal Environmental Protection Agency (FEPA) and National Agency for Food and Drug Administration and Control (NAFDAC) Standards for drinking water …
Published in Journal of Materials & Metallurgical Engineering · Vol. 14, Issue 1, 2024 · pp. 38–57 Read article
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Evaluating Linezolid: A Comprehensive Analysis
Abstract: Treatments for infections caused by Gram-positive bacteria, such as methicillin-resistant staphylococci and VRE, including skin and soft tissue infections, community-acquired pneumonia, and other infections treated with linezolid, an oxazolidinone antimicrobial agent that functions by specifically inhibiting protein synthesis. Even while antibiotic resistance is becoming more frequent in many nations, linezolid resistance among these pathogens is still low, typically less than 1%. Thus, the emergence of resistance in clinical isolates should …
Published in Research & Reviews: A Journal of Drug Design & Discovery · Vol. 11, Issue 2, 2024 · pp. 11–16 Read article
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Cognitive Emotional Regulation Strategies and Locus of Control among Substance Users
Abstract: Substance use is among the major health concern that creates significant disability in a person's mood and behavior, which leads to poor health and loss of productivity. Increasing substance use is associated with various short and long-term effects which affect how they deal with stress, regulate their emotions, decision making, and overall quality of life. The current research aims to Examine relationship between cognitive emotional regulation strategies and locus of …
Published in International Journal of Behavioral Sciences · Vol. 1, Issue 2, 2024 · pp. 01–09 Read article
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Towards Intelligent Healthcare: Artificial Intelligence’s Impact on Healthcare
Abstract: Artificial Intelligence (AI) stands as a transformative force within healthcare, offering multifaceted support to various processes and medical professionals. This comprehensive study investigates the extensive array of AI applications and its potential to reshape the healthcare landscape. Specifically, it examines the utilization of deep-learning methodologies in harnessing vast medical datasets to enhance healthcare provision. Expanding beyond theoretical discussions, this study scrutinizes AI's role in breast cancer, seizure, and tumor detection, …
Published in Journal of Artificial Intelligence Research & Advances · Vol. 11, Issue 2, 2024 · pp. 77–83 Read article
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Environmental Impact of Ghaf Tree (Prosopis cineraria) on Heavy Metals Concentration in Atmosphere
Abstract: The Ghaf is a hardy tree, drought-resistant, and can grow up to ten meters in height, it tree produces small, yellow flowers which attractive to many habitats, like bees, insects, and birds. The leaves and pods of the Ghaf tree have significant antioxidant and anti-inflammatory properties and can be used in new drug development. Ghaf trees can adapt to changing environmental conditions and planting Ghaf trees could be an effective …
Published in International Journal of Minerals · Vol. 1, Issue 1, 2024 · pp. 1–7 Read article
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Unlocking The Bioactivity Potential: Molecular Insights and Predictions of Salen, Salophen, Allicin, Curcumin, and Piperine
Abstract: In this work, the prediction of the biological activity of several significant molecules, including salen, salophen, allicin, curcumin, and piperine, are discussed. Using Molinspiration software, the molecular properties of these compounds were calculated. These molecules are highly significant due to their extensive potential in medical applications. Salen and salophen, for instance, play crucial roles in cancer chemotherapy and act as inhibitors of angiogenesis. Curcumin is renowned for its antioxidant properties, …
Published in International Journal of Cheminformatics · Vol. 1, Issue 2, 2023 · pp. 14–21 Read article
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Clinical experience with Ayurvedic Treatment in Case of Rheumatoid Arthritis – Ayurvedic review and Case study
Abstract: Rheumatoid arthritis is the most found inflammatory auto immune disease with unknown etiology. Many clinical features and treatment strategies of RA are associated with multiple joint diseases. The clinical phenotype of Rhematoid arthritis is a symmetrical, deformed polyarthritis of small and large joints, which is often associated with features of the disease. The treatment typically involves ongoing management with periods of worsening symptoms followed by periods of improvement. Features of …
Published in Research and Reviews : A Journal of Ayurvedic Science, Yoga and Naturopathy · Vol. 11, Issue 2, 2024 · pp. 1–8 Read article