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1147 articles for “system optimization”
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Screening of Pharmaceutically Significant Methioninase-Producing Fungi from the Satpura Range of Hoshangabad District and Its Large-Scale Production
Abstract: L-methioninase, an enzyme with notable anticancer properties, has emerged as a promising therapeutic agent due to its ability to selectively degrade methionine, a critical amino acid for the survival of methionine-dependent cancer cells. Methionine dependency, observed in many tumor cells, is a metabolic vulnerability that can be exploited for targeted cancer therapy. The Satpura Range in the Narmadapuram District, India, with its diverse microbial ecosystems, offers a rich reservoir for …
Published in Research & Reviews: A Journal of Bioinformatics · Vol. 12, Issue 2, 2025 · pp. 33–43 Read article
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Accelerating Drug Discovery with AI: Transforming the Pharmaceutical Pipeline
Abstract: The revolutionary potential of artificial intelligence (AI) is examined in this essay the pharmaceutical industry, highlighting its application across the drug development lifecycle. Artificial Intelligence, specifically via deep learning models and machine learning (ML) such as GANs, RNNs, and transformers, enhances drug discovery, formulation, toxicity prediction, and clinical trials. It streamlines processes like identification of targets, virtual screening, modelling of structure-activity relationships, and medication repurposing. AI is also employed in …
Published in Research & Reviews: A Journal of Drug Design & Discovery · Vol. 12, Issue 2, 2025 · pp. 77–84 Read article
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Comparative Analysis on Concrete Strength Using Various Sizes of Aggregates and Combined Gradation
Abstract: This research delves into the effect of using various single coarse aggregate sizes and combinations of such by specific proportions. A thorough examination involving control specimens of 12mm, 20mm, and 25mm aggregates sizes, with combining proportions in the ratios – 5/8:3/8, 1/2:1/2, 3/8:5/8 have been conducted, shedding light on critical patterns that dictate concrete performance. The fine aggregate was properly zoned from the preliminary test. The design mix was calculated …
Published in Recent Trends in Civil Engineering & Technology · Vol. 14, Issue 1, 2024 · pp. 29–36 Read article
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Integrative Machine Learning Approaches for Predicting the Rheological Behaviour of Soft Magnetorheological Elastomers
Abstract: Magnetorheological Elastomers (MREs) are advanced composite materials known for their ability to alter mechanical properties under external magnetic fields, making them highly valuable in adaptive damping systems, vibration control, and smart devices. The accurate prediction of rheological behavior in soft MREs remains a significant challenge due to the complex interplay between material composition and magnetic fields. To address this challenge, this study employs a multi-pronged approach that integrates traditional material …
Published in Journal of Polymer & Composites · Vol. 13, Issue 1, 2025 · pp. 1083–1096 Read article
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Enhancing Robot Autonomy: Integrating AI for Advanced Decision-making in Autonomous Robotic Systems
Abstract: The capabilities of autonomous robotic systems have been drastically changed by the rapid progress in artificial intelligence (AI) technologies. In this work, we investigate the integration of AI approaches to improve robot autonomy by presenting even more advanced mechanisms for decision-making. Almost all traditional robotic systems involve predefined algorithms, making them unable to cope with dynamic environments. They can also help with learning based on machine learning and deep learning …
Published in Journal of Advancements in Robotics · Vol. 11, Issue 3, 2024 · pp. 28–37 Read article
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Advancing Gene Therapy: Next-Generation Viral Vector Engineering for Precision, Safety, and Scalability
Abstract: Gene therapy has emerged as a paradigm-shifting modality for the treatment of genetic disorders, malignancies, and rare diseases through the delivery of therapeutic nucleic acids aimed at correcting or modulating dysfunctional gene expression. Among the various delivery systems, viral vectors including adeno-associated viruses (AAVs), lentiviruses, adenoviruses, retroviruses, and herpes simplex viruses have proven indispensable owing to their high transduction efficiencies and adaptability. This review offers a comprehensive assessment of viral …
Published in International Journal of Virus Studies · Vol. 2, Issue 2, 2025 · pp. 37–55 Read article
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IoT-Based Smart Electrical Board Using Google Assistant: An Enhanced Approach
Abstract: The Internet of Things (IoT) has revolutionized home automation by enabling seamless connectivity between smart devices and cloud services. By enabling intelligent and remote control of home systems like lighting, security, and climate control, this integration greatly enhances user control, convenience, and efficiency. The study introduces an improved IoT smart electrical board that can be connected to Google Assistant to enable voice commands for controlling household appliances. By combining modern …
Published in Journal of VLSI Design Tools and Technology · Vol. 15, Issue 2, 2025 · pp. 1–5 Read article
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High Performance Multi-Valued Logic (MVL)Gate Design Using FinFET
Abstract: CMOS scaling faces challenges such as leakage, power dissipation, and short channel effects. Multi-Valued Logic (MVL) offers higher information density and reduced interconnections. This work presents a FinFET-based MVL gate design that improves electrostatic control, switching speed, and reliability. Simulation results confirm reduced leakage power and enhanced performance compared to conventional logic. The proposed architecture demonstrates scalability for advanced technology nodes. It also shows potential for low-power applications in portable …
Published in Journal of Microelectronics and Solid State Devices · Vol. 13, Issue 1, 2026 · pp. 34–45 Read article
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A Review on Energy Storage System Enhancing the Stability of Micro grids
Abstract: Microgrids constitute decentralized energy systems that rely on various distributed renewable energy sources (DERs), such as solar panels, wind turbines, and power and heat production plants. Energy Storage Systems (ESS) help improve the stability and reliability of microgrids by decreasing the intermittent nature of renewable energy sources. This analysis examines how microgrids are classified and how ESS might help improve power quality and system dependability. It explores the many stability …
Published in International Journal of Electrical Machine Analysis and Design · Vol. 3, Issue 1, 2025 · pp. 1–6 Read article
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Design of Maritime Empennage Unmanned Aerial Vehicle (UAV): A Comprehensive Study
Abstract: This project presents a comprehensive study on the design and development of a maritime empennage unmanned aerial vehicle (UAV) tailored for operations in coastal and naval environments. The primary objective is to engineer an efficient, stable, and mission-adaptable UAV with an optimized empennage configuration that enhances aerodynamic performance and control in maritime conditions. The study involves a systematic design process encompassing mission requirement analysis, conceptual and preliminary design, aerodynamic modeling, …
Published in Journal of Aerospace Engineering & Technology · Vol. 16, Issue 1, 2026 Read article
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Hybrid Braking System: Electromagnetic + Disc Braking
Abstract: The Hybrid Braking System combines electromagnetic braking and traditional disc braking to enhance vehicle safety, improve braking response, and reduce mechanical wear. This system integrates sensor fusion technologies, including ultrasonic and infrared sensors, to enable adaptive braking based on real-time road conditions. A PID-based control algorithm optimizes braking force distribution, ensuring a smooth and controlled deceleration. Additionally, the incorporation of regenerative braking allows for energy recovery, increasing vehicle efficiency and …
Published in International Journal of Mechanical Dynamics and Systems Analysis · Vol. 4, Issue 1, 2026 · pp. 8–14 Read article
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Exploring the Thyroid Gland Physiology in Relation to Thyroid Hormones: An Overview through the Lens of 3D Computational Biology
Abstract: The endocrine system plays a pivotal role in orchestrating and sustaining diverse physiological functions by manufacturing and releasing hormones, which function as vital chemical messengers within the body. Among the prominent endocrine glands, the thyroid gland holds a central position. Situated in the lower part of the neck, this gland adopts a butterfly-shaped structure. Its significance lies in the synthesis of three key hormones: thyroxine (T4), tri-iodothyronine (T3), and calcitonin.The …
Published in Research & Reviews: A Journal of Bioinformatics · Vol. 11, Issue 1, 2024 · pp. 46–54 Read article
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Optimization of Structural Health Monitoring Using Artificial Neural Network and Comparison with Traditional Method: A Comprehensive Review
Abstract: Structural health monitoring (SHM) has a critical role in ensuring civil infrastructure safety, reliability, and durability through real-time, condition-based monitoring. Traditional SHM systems employ hundreds of sensors such as accelerometers, strain gauges, and displacement transducers for monitoring vast amounts of data for structural inspection, but do not effectively manage complicated nonlinear data. This research paper, “Optimization of Structural Health Monitoring Using Artificial Neural Network and Comparison with Traditional Methods,” investigates …
Published in Journal of Structural Engineering and Management · Vol. 13, Issue 1, 2026 · pp. 23–33 Read article
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Learning Data Structures: Key to Good Programming
Abstract: Data structures are the most crucial feature of good programming and are needed to solve hard computational problems. This model makes use of two different recurrent neural network architectures, specifically long short-term memory (LSTM), and gated recurrent unit (GRU) networks. It explains how selecting and using the correct data structures may speed up computations, optimize memory, and scale code. How data structures and algorithms relate and how to think about …
Published in International Journal of Data Structure Studies · Vol. 4, Issue 1, 2026 · pp. 29–39 Read article
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A Review of Blocking Side-Channel Threats in Parallel Cloud Systems
Abstract: Side-channel attacks (SCAs) pose a critical security threat to parallel computing systems, particularly in shared cloud environments where multi-tenancy and resource contention create exploitable vulnerabilities. This study presents a comprehensive review of SCAs in parallel architectures, analyzing attack vectors such as cache-based exploits (e.g., Prime + Probe, Flush + Reload), timing attacks, power analysis, and network-based covert channels. We examine real-world cases including Spectre and Meltdown vulnerabilities that exposed fundamental …
Published in Recent Trends in Parallel Computing · Vol. 12, Issue 2, 2025 · pp. 15–25 Read article
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Why Sheep Matter? A Holistic Perspective on Productive, Social, and Economic Benefits
Abstract: The comparative advantages of raising sheep over goats have significant implications for productive, social, cultural, and economic perspectives in livestock farming systems. Sheep farming offers unique benefits, including superior wool production, higher carcass yields, and greater adaptability to diverse climates and grazing systems. Sheep are more efficient in utilizing low-quality forages, exhibit better reproductive performance with higher lambing percentages, and demonstrate reduced susceptibility to diseases, resulting in lower veterinary costs. …
Published in Research and Reviews : A Journal of Life Sciences · Vol. 15, Issue 2, 2025 · pp. 9–25 Read article
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Greenhouse Monitoring Robot
Abstract: In the realm of agriculture, where sustainable food production is paramount, the Greenhouse Monitoring Robot emerges as a game-changing project. Greenhouse farming, with its year-round cultivation and resource efficiency, relies on precise environmental control, notably temperature and humidity. This paper focuses on the successful implementation of an autonomous Line-Following Robot equipped with sensors like the DHT11 to ensure an ideal greenhouse environment. This innovative solution has enabled the accurate recording …
Published in International Journal of Robotics and Automation in Mechanics · Vol. 1, Issue 1, 2023 · pp. 11–16 Read article
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Electric Vehicle Charging Station: A Simulation-based Study
Abstract: Electric Vehicle (EV) is a current buzz in the automotive industry. As electric vehicles (EVs) become more widely used, there is an increasing need for reliable and easily accessible charging infrastructure. In order to meet the expanding demands of EV users while maintaining sustainability and scalability, this abstract describes the design and optimization of an infrastructure for electric vehicle charging stations (EVCS). The aim of this project is to design …
Published in Journal of Automobile Engineering and Applications · Vol. 11, Issue 1, 2024 · pp. 32–42 Read article
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AI-Designed Functionally Graded Polymer Composites for Multifunctional Thin Films
Abstract: The design of multifunctional polymer composite thin films requires simultaneous optimization of mechanical, optical, barrier, and thermal properties—objectives often in conflict when using conventional homogeneous materials. This study presents an artificial intelligence-driven framework for designing functionally graded material (FGM) architectures in polymer nanocomposite thin films. We integrated machine learning with physics-based modeling to optimize compositional gradients across film thickness, achieving superior performance compared to homogeneous and discrete multilayer alternatives. A …
Published in Journal of Polymer & Composites · Vol. 14, Issue 2, 2026 · pp. 1026–1041 Read article
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Impact of Vaccine Awareness Campaigns on Pharmacovigilance Reporting and Public Safety Monitoring
Abstract: Vaccination programs have significantly contributed to the reduction of infectious diseases worldwide; however, their success is closely tied to public confidence and robust safety monitoring systems. Pharmacovigilance plays a critical role in identifying, assessing, and preventing adverse events following immunization (AEFI). In recent years, vaccine awareness campaigns have emerged as a pivotal strategy to improve public knowledge, reduce vaccine hesitancy, and enhance reporting of adverse drug reactions (ADRs). This review …
Published in International Journal of Vaccines · Vol. 3, Issue 2, 2026 · pp. 1–14 Read article