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668 articles for “development” (ranking capped at the first 2,000 matches — narrow the search to see the rest)
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Molecular Docking Analysis of Phytocompounds from Ficus hispida Aagainst Epidermal Growth Factor Receptor Kinase Domain
Abstract: The Epidermal Growth Factor Receptor (EGFR) kinase domain plays a key role in cancer, as it promotes tumour growth and helps cancer cells survive, making it an important focus for developing treatments. Through comprehensive computational analysis, this study investigates the anticancer potential of phytocompounds from Ficus hispida, a medicinal plant renowned for its diverse bioactive compounds, as novel EGFR inhibitors. Molecular docking techniques using Py Rx software were employed to …
Published in International Journal of Cell Biology and Cellular Functions · Vol. 3, Issue 2, 2025 Read article
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Molecular Docking Analysis of Phytocompounds from Ficus hispida Against Epidermal Growth Factor Receptor Kinase Domain
Abstract: The Epidermal Growth Factor Receptor (EGFR) kinase domain plays a key role in cancer, as it promotes tumour growth and helps cancer cells survive, making it an important focus for developing treatments. Through comprehensive computational analysis, this study investigates the anticancer potential of phytocompounds from Ficus hispida, a medicinal plant renowned for its diverse bioactive compounds, as novel EGFR inhibitors. Molecular docking techniques using Py Rx software were employed to …
Published in International Journal of Cell Biology and Cellular Functions · Vol. 3, Issue 2, 2025 · pp. 48–62 Read article
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Prediction of Molecular Targets for Anthraquinone and Its Analogs for Treatment of Good Pasteur Syndrome
Abstract: Objective: In order to find prospective molecular targets for the treatment of Good Pasteur Syndrome (GPS), a rare autoimmune disease that affects the kidneys and other organs, computational methods and network pharmacology were applied in this work. The goal of the study is to identify particular human proteins that might interact with anthraquinone and its analogues as well as to uncover potential mechanisms of action by which these drugs might …
Published in International Journal of Bioinformatics and Computational Biology Read article
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Melanogenic Inhibitory Effects of Sesamum indicum Phytocompounds Towards CDK 2, c-KIT, and BRAF.
Abstract: Objective: Melanoma is thought to be the fifth most frequent cancer in the US population, despite cancer being the most common cause of death in the globe. BRAF, CDK2, and c-KIT proteins are regarded as potential therapeutic agents since mutations in these proteins are the primary cause of melanoma. For the investigation of their pharmacological properties and therapeutic activities against the target proteins, Sesamum indicum L. and its phytocompounds were …
Published in International Journal of Bioinformatics and Computational Biology Read article
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Impact of Project Complexities on Cost Overruns
Abstract: As decision-making and goal setting become more challenging due to complexity, there is growing consensus that comprehending complexity is essential for project management. However, there have been concerns expressed regarding how complexity can be quantified in a reliable way that takes into account structural, dynamic, and interaction factors. Current operational definitions of complex projects based on size and budget, have been called into doubt. What can be done is to …
Published in International Journal of Architectural Design and Planning Read article
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Breast Feeding Practices Among Rural Women
Abstract: Introduction: Breastfeeding is an unequalled way of providing ideal food for the healthy growth and development of infants. As per the national family health survey-3 (NFHS-3), only 46% of the Indian infants between 0 and 6 months are exclusively breastfed. Hence the following study was done to know the practice of breastfeeding in mothers of rural and urban areas of India. Method- The study was carried out in a rural …
Published in International Journal of Women's Health Nursing And Practices · Vol. 1, Issue 1, 2023 · pp. 01–08 Read article
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Cultural Heritage of Punjab: A Shift in Outlook and Output—A Case Study of the Historical Town of Sirhind
Abstract: Cultural heritage is an expression of ways of living developed by a community and passed on from generation to generation. This could be the tangible assets, such as buildings, monuments, archaeological sites, artifacts, landscape, and intangible assets such as oral traditions, folklore, language, and knowledge. Though all these can be viewed, analyzed, studied separately, they cannot be experienced as standalone entities. The understanding of our cultural heritage is fragmented and …
Published in International Journal of Architectural Design and Planning Read article
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Cost Model of Acquisition and Merger in Construction Industry
Abstract: Merger and Acquisition in India is at an all-time high with more buyers now than before; it has been accounting for 80% of closed deals in 2020–2021, up from 70% in 2017–2019. To determine the Merger and Acquisition of the company, this article explores the main factors in the Merger and Acquisition process. And also study the main framework of the Merger and Acquisition. And, also, the article discusses the …
Published in International Journal of Architectural Design and Planning Read article
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"Achieving Sustainability Through Building Adaptationt"
Abstract: Building adaptation has a significant impact on sustainable development. There are various aspects of building obsolescence that affect the quality and performance of the building after its useful lifecycle, which include reduced environmental, economic, functional and social performance. Timely and effective building adaptation of the buildings which are facing obsolescence can extend its effective lifespan and this can provide considerable economic, environmental and social benefits, making it a sustainable alternative …
Published in International Journal of Environmental Planning and Development Architecture · Vol. 1, Issue 1, 2023 · pp. 27–32 Read article
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An Integrated Study to Extrapolate the Interaction of NMDAR with Potential Ligands for the Treatment of Alzheimer’s Disease Symptoms
Abstract: Objective: Alzheimer’s disease (AD) is the most common neurodegenerative disease affecting the health status of older adults especially those above the age of 60 years. As an outcome, two types of medications have been developed for the treatment of its symptoms which are acetylcholinesterase (AChE) and N-methyl-D-aspartate receptor (NMDAR) antagonist. This paper uses the computational approach to understand the interaction of NMDAR with four major phytocompounds (curcumin, L-epicatechin, ginsenosides, and …
Published in International Journal of Biochemistry and Biomolecule Research · Vol. 1, Issue 1, 2023 · pp. 15–27 Read article
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Investigate an Implementation Study of TI-6AL-4V Lattice-based Scaffold Design Using Finite Element Analysis
Abstract: Implementation studies are advised to determine the effectiveness and performance of bone scaffolding in morphology, which has been demonstrated scientifically. The rehabilitation of bone defects, which is still a complex problem in orthopedic surgery, was the subject of an implementation study we provided. Biomaterial scaffolding porosity and pore size are essential in both in vivo and in vitro bone development. However, it has been linked to various drawbacks, including poor …
Published in International Journal of Biochemistry and Biomolecule Research · Vol. 1, Issue 1, 2023 · pp. 28–35 Read article
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Anti Covid-19 Drugs Suggested by Computational Methods: A Review
Abstract: Background and aims: Long COVID refers to the persistence of illness in individuals who have survived from COVID-19 infection. This article reviews long covid and the use of in silico techniques in drug development for COVID-19. Results: Many COVID-19 survivors have long COVID, which has become a burden in daily life. Various attempts have been undertaken to relieve symptoms and manage it, but there is no cure as of yet. …
Published in International Journal of Cell Biology and Cellular Functions · Vol. 1, Issue 1, 2023 · pp. 16–34 Read article
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Assessing the Knowledge and Attitudes of Eligible Couples Regarding Small Family Norm in a Selected Rural Area of Gwalior
Abstract: This study aimed to determine the level of knowledge and attitude of eligible couples toward permanent family planning methods in a selected rural area of the district. The research method was an evaluation. Sixty couples were chosen at random who met the inclusion and exclusion criteria. The primary purpose of this research is to evaluate the level of understanding and satisfaction with permanent family planning methods among eligible couples in …
Published in International Journal of Community Health Nursing And Practices · Vol. 1, Issue 2, 2023 Read article
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Identification and Assessment of the Factors causing Cost Overrun in Housing Projects
Abstract: Poor cost performance is a major problem in construction industry, especially in developing countries like India. Statistics reveal that majority of the projects faces the issue of cost overrun. The interrelationship between the causes of cost overrun and stakeholders has not been explored yet. The aim of the research is to minimize the effects of project cost overrun. The objective of the study is to categorize and rank the potential …
Published in International Journal of Urban Design and Development · Vol. 1, Issue 1, 2023 · pp. 17–34 Read article
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Matching Minutiae Fingerprint Q-Learning Approach for Detail Coordination: Identifiable Mark Point
Abstract: The use of fingerprints for high-precision recognition and identification of people is one of the most reliable biometric symbols because it is non-invasive. In this paper, we propose an innovative approach to detect details on low contrast resolution image quality of fingerprint images. Existing algorithms are not very susceptible to sound and image excellence due to the lack of level of intensity. We recommend a reliable route to find fingerprints …
Published in International Journal of Information Security Engineering · Vol. 1, Issue 1, 2023 · pp. 1–15 Read article
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Multiple Sclerosis: A Systematic Review of a Neurological Disorder
Abstract: The inflammatory illness known as multiple sclerosis (MS) is brought on by outside influences that affect a biologically vulnerable host. It has 3 separate diagnostic phases: the pre-clinical phase, which can only be discovered by MRI; the relapsing-remitting (RRMS) phase, which again is defined by bouts of neurological malfunction accompanied by remission; and the progressing phase, which often develops from either the relapse phase. Unfortunately, the majority of relapse MS …
Published in International Journal of Genetic Modifications and Recombinations · Vol. 1, Issue 1, 2023 · pp. 53–71 Read article
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The Current State of Huntington's Disease Treatment: An Overview of Palliative Care and Symptom Management
Abstract: Huntington's disease (HD) is a neurodegenerative ailment that adversely affects the basal ganglia and the cortex of the brain. Although there is no recognized cure for HD, symptomatic relief and therapeutic management of the condition have improved over the course of time. This review paper provides an up-to-date overview of the current treatment options and symptom management strategies utilized in the care of HD patients. Additionally, it highlights the existing …
Published in International Journal of Cell Biology and Cellular Functions · Vol. 1, Issue 1, 2023 Read article
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A Critical Study of Research Challenges for Self-adaptive Software
Abstract: Software systems dealing with distributed applications in changing environments normally require human supervision to proceed with activity in all conditions. These rearranging, investigating, and all in all upkeep errands prompt exorbitant and tedious strategies amid the working stage. These issues are principally because of the open-circle structure regularly followed in programming advancement. Hence, there is popularity for administration many-sided quality decrease, administration mechanization, vigor, and accomplishing the majority of the …
Published in International Journal of Computer Science Languages · Vol. 1, Issue 1, 2023 · pp. 1–6 Read article
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Essential Self-Breast Examination for Both Men and Women
Abstract: Breast self-examination stands as a crucial and foundational technique for the early detection of irregularities within the breast tissue, including both the breast itself and the nipple. This method is accessible and relevant to individuals of all genders, involving fundamental principles of observation and palpation. Those well-versed in breast self-examination possess the knowledge to guide others in this practice, which can lead to early intervention and, ultimately, the prevention of …
Published in International Journal of Midwifery Nursing And Practices · Vol. 1, Issue 2, 2023 · pp. 19–23 Read article
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The Nursing Perspective: Emerging Competencies in Midwifery and Neonatal Care
Abstract: A skilled attendant is a qualified healthcare practitioner, such as a midwife, doctor, or nurse, who has received appropriate education and training to effectively handle uncomplicated pregnancies, childbirth, and the immediate postnatal period. They are equipped to identify, manage, and refer any complications that may arise in women and newborns. Skilled attendants have the necessary knowledge and skills to manage normal pregnancies and childbirth, and their presence during delivery is …
Published in International Journal of Women's Health Nursing And Practices · Vol. 1, Issue 1, 2023 · pp. 21–26 Read article