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1186 articles for “Treatment”
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The Concept of Guillain-Barré Syndrome (GBS) in Unani Medicine and the Potential Role of Unani Pharmacology in Its Management
Abstract: Introduction: Guillain–Barré Syndrome (GBS) is an autoimmune neurological disorder characterized by progressive muscle weakness and paralysis due to immune-mediated damage to the peripheral nervous system. Conventional treatments focus on immunotherapy and supportive care, but alternative approaches, such as Unani Medicine offer promising holistic management strategies. Unani Medicine attributes GBS to humoral imbalance, particularly an excess of Balgham (Phlegm) affecting nerve function, leading to weakness and dysfunction. Objective: This study aims …
Published in Journal of AYUSH: Ayurveda, Yoga, Unani, Siddha and Homeopathy · Vol. 14, Issue 2, 2025 · pp. 32–52 Read article
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Fabrication and Characterization of Diacerein Loaded Nanosponge for Topical Delivery
Abstract: Diacerein, an anti-inflammatory drug, which comes under BCS class II, commonly used in treatment of osteoarthritis has limited by its poor solubility and bioavailability when administered topically. This study aimed to develop and evaluate diacerein-loaded nanosponges gel using varying concentrations of ethyl cellulose and polyvinyl alcohol (PVA) to enhance its delivery. Nanosponges were prepared using an emulsion solvent evaporation technique, with different ratios of ethyl cellulose (0.05-0.250%) and PVA (0.2-0.3%). …
Published in Research & Reviews: A Journal of Drug Formulation, Development and Production · Vol. 12, Issue 2, 2025 · pp. 26–46 Read article
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The concept of Sū’-i-mizāj Nukhā and A‘ṣāb
Abstract: The Unani system of medicine provides a holistic understanding of neurological disorders, emphasizing the role of Su’-i-Mizaj (dystemperament) in the spinal cord (Nukhā) and nerves (A‘ṣāb). According to Unani scholars like Ali Ibn Abbas Majusi, disturbances in the mizaj-e-tabai (natural temperament) of Nukhā lead to various neurological conditions, categorized into Istirkhā’ (Flaccidity), Abar Bilqisiya (Bell’s Palsy), Khaddar (Numbness), Tashannuj (Convulsions), and Ra‘sha (Tremors).The most common dystemperament in Nukhā and A‘ṣāb …
Published in Journal of AYUSH: Ayurveda, Yoga, Unani, Siddha and Homeopathy · Vol. 14, Issue 2, 2025 · pp. 53–57 Read article
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Innovations in Healthcare IT for Enhanced Patient Outcomes
Abstract: Healthcare IT innovations are transforming medical services by enhancing diagnostics, improving patient management, and optimizing resource utilization. The integration of advanced technologies has led to significant improvements in healthcare delivery, enabling more accurate diagnoses, efficient treatments, and seamless data management. One of the most impactful advancements is Electronic Health Records (EHR), which facilitate centralized patient data storage, allowing healthcare providers to access and update records in real-time. Telemedicine has revolutionized …
Published in Current Trends in Information Technology · Vol. 15, Issue 2, 2025 · pp. 19–23 Read article
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Review on Unveiling the Shadow of Hyperpigmentation
Abstract: Natural products offer promising solutions for treating skin pigmentation disorders due to their non-toxic properties and effective mechanisms of action. Studies highlight their safety and efficacy through methods such as cytotoxicity tests, tyrosinase activity assays, and melanogenesis inhibition evaluations. Advanced delivery systems like liposomes and nanoparticles further enhance their performance by improving solubility and skin penetration. Skin pigmentation disorders, influenced by factors such as UV radiation, hormonal changes, and inflammation, …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 15, Issue 2, 2025 · pp. 59–66 Read article
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Rheumatoid Arthritis and Stem Cell Therapies Perspectives for It
Abstract: Rheumatoid arthritis (RA) is a chronic autoimmune disorder characterized by systemic inflammation, primarily affecting synovial joints, leading to joint destruction and systemic complications. The pathogenesis involves immune system dysregulation, autoantibody production, and enzymatic imbalances. Enzymes, including matrix metalloproteinases (MMPs), serine proteases, and kinases, play crucial roles in these processes. Their dysregulation contributes significantly to disease progression through the imbalance of pro-inflammatory cytokines, oxidative stress, and extracellular matrix (ECM) degradation. MMPs, …
Published in Research and Reviews : A Journal of Biotechnology · Vol. 15, Issue 2, 2025 Read article
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Study of the response of Fenugreek Seedlings (Trigonella foenum-graecum L.) to some Plant Growth Regulators and Their effect on the production of the active Compound (Trigonelline)
Abstract: The experiment was conducted during the 2022–2023 academic year in the laboratories of the Department of Biology, Faculty of Education for Girls, University of Kufa, to investigate the effects of varying concentrations of gibberellic acid (GA₃) — specifically 0, 2, and 3 ppm — and salicylic acid (SA) (0, 2.5, 5 ppm) as well as the interaction between them on the germination percentage and some growth traits of fenugreek seedlings …
Published in Research and Reviews : A Journal of Biotechnology · Vol. 15, Issue 2, 2025 Read article
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Role of Dermabrasion Assisted Tangential Excision in Paediatric Electrical Burn Wounds
Abstract: Early removal of necrotic tissue in deep electrical burns by tangential excision decreases scarring and promotes wound healing. Dermabrasion, traditionally used in dermatology for facial resurfacing and scar treatment, has shown promising results when applied to burn wound management. In burn care, dermabrasion serves as a form of blunt debridement, effectively removing superficial necrotic tissue without damaging underlying healthy structures. This technique helps reduce local inflammation and lowers the likelihood …
Published in Research and Reviews : Journal of Surgery · Vol. 14, Issue 2, 2025 Read article
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Thermosensitive and pH-Responsive Polymers for Smart Drug Delivery Systems
Abstract: Sensitive to temperature and pH, polymers are becoming a fascinating new class of material suitable for application in drug delivery systems. These polymers can be utilised in controlled release of medications as they change form depending on temperature and acidity. Thermosensitive polymers vary their formation and breakdown behaviour with temperature variations. They are therefore perfect for delivering pharmaceuticals to individuals as heat may be utilised to activate the medications at …
Published in Journal of Polymer & Composites · Vol. 13, Issue 4, 2025 · pp. 479–491 Read article
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Controlled Release of Anti-Inflammatory Drugs from Biopolymer Matrices
Abstract: Carefully releasing anti-inflammatory drugs from natural materials is a new way to make treatments work better and cut down on the side effects of current drug delivery methods. To slowly release drugs, this method uses safe, reusable materials. It's a good alternative to pills or shots. Anti-inflammatory drugs that are used to treat long-term conditions like gout and inflammatory bowel disease work better when they are made in a controlled …
Published in Journal of Polymer & Composites · Vol. 13, Issue 4, 2025 · pp. 388–399 Read article
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Microsphere and Nanoparticle Drug Delivery Systems: Role of Polymers in Pharmacology
Abstract: Microsphere and nanoscale drug delivery methods have changed the field of pharmacology by making treatment agents more bioavailable, more targeted, and easier to manage. These delivery systems, which are mostly made up of polymers, look like a good way to get around the problems that traditional drug formulations have, like not dissolving well, clearing quickly, and spreading in different places. Plastics are very important in the creation of these improved …
Published in Journal of Polymer & Composites · Vol. 13, Issue 4, 2025 · pp. 420–432 Read article
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Advances in Biodegradable Polymer-based Drug Delivery Systems
Abstract: An intriguing new approach to manage medication release that may assist with issues like making the therapeutic impact last longer, reducing the danger of side effects, and persuading patients to follow through with their treatment programs is biodegradable polymer-based drug delivery systems (DDS). By developing systems that can break down within the body, biodegradable polymers have revolutionised the way medications are administered. They so have less negative effects and do …
Published in Journal of Polymer & Composites · Vol. 13, Issue 4, 2025 · pp. 326–338 Read article
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Polymer Chemistry in Dental Applications: Advances and Innovations
Abstract: Polymer chemistry has revolutionized dental materials, offering enhanced mechanical strength, durability, and biocompatibility. The integration of polymer-based materials in dentistry has led to significant advancements in restorative, prosthetic, and preventive treatments. This paper explores the role of polymers in dental applications, focusing on composite resins, denture bases, impression materials, and adhesive systems. The development and alteration of polymers have led to the creation of advanced materials with enhanced wear resistance, …
Published in Journal of Polymer & Composites · Vol. 13, Issue 5, 2025 · pp. 16–22 Read article
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Stimuli-Responsive Polymers for Drug Release in Targeted Therapy
Abstract: SRPs, or stimuli-responsive polymers, are becoming a good way to give specific drugs. They let medicines be released in a controlled way. Some of the things that can change these polymers are pH, temperature, light, magnetic fields, and the number of ions present. Some outside signs can make SRPs respond, which helps control how drugs are released. This cuts down on side effects and improves the effectiveness of focused treatments. …
Published in Journal of Polymer & Composites · Vol. 13, Issue 4, 2025 · pp. 252–265 Read article
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Pharmacokinetics and Stability of Polymer-Encapsulated Drugs
Abstract: Making drugs that are covered by plastics is a fresh and useful way to make medicines work better, last longer, and treat diseases better. Putting drugs inside polymer materials helps them breakdown better, stays in the body longer, and lowers the number of side effects they cause. This is necessary to slowly release the drug and help people stick to their treatment plan. Polymers are used to wrap drugs. This …
Published in Journal of Polymer & Composites · Vol. 13, Issue 4, 2025 · pp. 349–361 Read article
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Cardiovascular Modeling with Computational and Mathematical Methods
Abstract: The cardiovascular system, a complex network responsible for delivering life-sustaining oxygen and nutrients throughout the body, is a prime target for advanced understanding and improved therapies. Due to the inherent difficulties in directly observing internal physiological processes and the complexities of interactions within the system, computational and mathematical modeling have emerged as powerful tools in cardiovascular research. This article explores the significance of these methods in unveiling the heart's secrets …
Published in Research & Reviews: A Journal of Bioinformatics · Vol. 12, Issue 2, 2025 · pp. 11–21 Read article
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Repurposing Liv-52 For Primary Sclerosing Cholangitis: A Computational Docking And Pharmacokinetic Study To Evaluate Its Bile Flow-Regulating Potential
Abstract: Primary Sclerosing Cholangitis (PSC) is a long-term liver disease where the bile ducts become inflamed and scarred over time. This scarring can block the flow of bile, leading to liver damage and, eventually, liver failure. The etiology of PSC remains largely unknown, and current treatment options are limited, highlighting the need for novel therapeutic strategies. This study aims to repurpose Liv-52, a traditional herbal formulation known for its hepatoprotective properties, …
Published in Research and Reviews : Journal of Computational Biology · Vol. 14, Issue 2, 2025 Read article
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Strategies to Improve Drug Compliance Among Patients with Mental Disorders: A Systematic Review
Abstract: Background: Mental disorders constitute a public health concern, accounting for 13% of the global disease burden. Pharmacotherapy along with psycho education is primary line of treatment and maintaining drug compliance is crucial. Aim: The aim of this systematic review was to summarize the strategies to improve drug compliance among patients with mental disorders, identify which tools are most frequently used to measure strategies to improve drug compliance among patients with …
Published in International Journal of Evidence Based Nursing And Practices · Vol. 3, Issue 1, 2025 · pp. 74–81 Read article
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First Insights into Whole Genome Sequencing of the Mycobacterium tuberculosis Complex: Molecular Diversity and Drug Susceptibility Patterns in Senegal
Abstract: Background: We conducted a bibliographic analysis of the Mycobacterium tuberculosis complex (MTBC) in sub-Saharan Africa, which included the analysis of 8,139 genomic sequences from 34 of the 49 sub-Saharan African countries. Notably, only one complete sequence from Senegal was identified, which had been generated in the United States. Our primary objective was to utilize whole genome sequencing (WGS) to detect resistance in anti-tuberculous strains of the MTBC in Senegal. This …
Published in Recent Trends in Infectious Diseases · Vol. 2, Issue 1, 2025 Read article
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AI Application in the Creation of Medications for COPD
Abstract: The crippling lung condition known as chronic obstructive pulmonary disease (COPD) is typified by a continuous restriction of airflow, which results in increased respiratory dysfunction and a reduced quality of life. The rising incidence of COPD worldwide emphasizes the pressing need for innovative pharmaceutical approaches to address the illness. Even though COPD care has advanced significantly, most current medications concentrate on symptom relief rather than disease change. This gap in …
Published in Research & Reviews: A Journal of Drug Design & Discovery · Vol. 12, Issue 2, 2025 · pp. 01–05 Read article