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1260 articles for “CTLA-4”
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AI-Accelerated Development of Gradient Polymer Nanocomposite Thin Films
Abstract: Gradient polymer nanocomposite thin films are an active field of materials research due to the fact that it enables scientists to de-facto regulate the optical, electrical, and mechanical properties of a film by merely altering its composition on a layer-by-layer basis. This type of control opens the gate to the improved flexible electronics, long lasting protective coats, and the new smart gadgets. The problem is, though, that it is a …
Published in Journal of Polymer & Composites · Vol. 14, Issue 2, 2026 · pp. 456–469 Read article
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An Integrated Simulation Framework for Predicting Dielectric Breakdown and Electrical Aging in Epoxy-Silica Composite Insulation Systems
Abstract: This paper provides a combined computation approach in forecasting the dielectric breakdown and electrical aging within epoxy-silica composite of insulation system. The approach will consist of a three-complementary methodology (a combination of computing electric field using the finite element analysis, estimation of the probability of failures or breakdowns using Weibull statistics, and prediction of degradation tendencies using artificial neural networks). The epoxy-silica composites are of 10-40 volumes fillers. The simulations …
Published in Journal of Polymer & Composites · Vol. 14, Issue 2, 2026 · pp. 339–376 Read article
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Assessing Urban Surface Runoff Management Using the SWAT Model, GIS, and the Rational Method: A Case Study of Karapakkam
Abstract: Urban surface runoff management encompasses strategies aimed at regulating rainwater flow, reducing urban flooding, enhancing groundwater recharge, and contributing to disaster risk mitigation for sustainable urban development. This study seeks to optimize surface runoff management in urban settings by using the soil and water assessment tool (SWAT) model integrated with geographic information systems (GIS) to minimize flood risks. The research focuses on the peak runoff in Karapakkam, a locality within …
Published in International Journal of Environmental Planning and Development Architecture · Vol. 4, Issue 1, 2026 · pp. 37–48 Read article
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Variation in Ozone at Night in Barrow, Alaska, during Different seasons, and its Relationship to Methane at Different Pressures
Abstract: The study is focus on the investigation of the night-time seasonal variability of ozone (O₃) at Barrow, Alaska, and also it examines its association with methane (CH₄) concentrations at different pressure levels along with solar flux variations on the basis of eighteen years (2003–2020) of observational data, including ground-based ozone measurements, satellite-derived methane data at 100, 200, 300, 400, and 500 hPa, and solar flux (F10.7) values. For finding the …
Published in International Journal of Atmosphere · Vol. 3, Issue 1, 2026 · pp. 44–53 Read article
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Effect of Unani Formulation in the Management of Non-Healing Ulcer – A Case Report
Abstract: Background and Aim: A non-healing ulcer (Qurooh-e-Aseerul-Indemal) of the foot is characterized by a persistent deterioration of the epidermal and dermal layers of the skin on the foot, continuing for more than six weeks without showing signs of recovery. Non-healing ulcers represent a significant global health challenge, markedly affecting patient well-being and imposing a considerable burden on their families. Global prevalence ranges between 1.9% to 13.1%, while in India, the …
Published in Research & Reviews : A Journal of Unani, Siddha and Homeopathy · Vol. 13, Issue 1, 2026 · pp. 7–12 Read article
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Sudarshan Kriya Intervention and Rise of Protective Prostaglandins in Advanced-Stage Breast Cancer: Double-Blind, Randomized, Controlled Trial
Abstract: Background: Breast cancer patients in advanced stages of cancer are managed by palliative care. This study reports important prostaglandin changes observed with added intervention of Sudarshan Kriya in their ongoing palliative care. Level of Prostaglandin A₂ (PGA₂) indicates tumor growth suppression; its level rises if person’s general condition is good, physically fit and active while PGE₂ and D₂ are considered pro-inflammatory. Quantitative assessment of Prostaglandins was done pre and post …
Published in Journal of AYUSH: Ayurveda, Yoga, Unani, Siddha and Homeopathy · Vol. 15, Issue 1, 2026 · pp. 62–68 Read article
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AI-Designed Functionally Graded Polymer Composites for Multifunctional Thin Films
Abstract: The design of multifunctional polymer composite thin films requires simultaneous optimization of mechanical, optical, barrier, and thermal properties—objectives often in conflict when using conventional homogeneous materials. This study presents an artificial intelligence-driven framework for designing functionally graded material (FGM) architectures in polymer nanocomposite thin films. We integrated machine learning with physics-based modeling to optimize compositional gradients across film thickness, achieving superior performance compared to homogeneous and discrete multilayer alternatives. A …
Published in Journal of Polymer & Composites · Vol. 14, Issue 2, 2026 · pp. 1026–1041 Read article
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Nitrosamine Accumulation, Processing Variables, and Indigenous Plant Inhibitors in Nigerian Traditionally Processed Meats
Abstract: N-nitrosamines are classified as probable or possible human carcinogens by the International Agency for Research on Cancer. Carcinogenic N-nitrosamines — principally N-nitrosodimethylamine (NDMA) and N-nitrosodiethylamine (NDEA) — are formed in abundance during the preparation of widely consumed Nigerian traditional processed meats including suya, kilishi, and balangu. This original investigation combined a six geopolitical zone of Nigerian market survey with laboratory-controlled model system experiments, effects of processing parameters on N-Nitrosamine formation …
Published in Journal of Modern Chemistry & Chemical Technology · Vol. 17, Issue 1, 2026 · pp. 61–72 Read article
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An Overview Mechatronics Systems Design of Modelica-Based Model Predictive Control Strategies for CO₂ Heat Pump Systems
Abstract: The growing adoption of renewable energy technologies poses challenges to energy supply stability, necessitating increased flexibility in energy demand. This paper introduces a Modelica-based Model Predictive Control (MPC) strategy aimed at keeping the supply water temperature within the range of 55°C to 75°C while minimizing energy consumption and electricity expenses throughout a year. A comprehensive, high-fidelity model representing a school building in Oslo, Norway, was developed using Modelica and exported …
Published in Journal of Mechatronics and Automation · Vol. 13, Issue 1, 2026 · pp. 15–27 Read article
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Thermal Stability and Sound Absorption Behaviour of Sisal–Luffa Hybrid Epoxy Composites for Automotive Interior Applications
Abstract: Natural fiber–reinforced composites are gaining popularity as substitutes for synthetic fiber composites because of their environmental and sustainability advantages. Their adoption is steadily increasing across various industries. In automotive interior applications, these materials must exhibit strong thermal stability and efficient sound absorption to meet performance requirements. In this experiment, composites were made by mixing sisal and luffa fibers with epoxy resin. The hand lay-up method was used for fabrication. Two …
Published in Journal of Polymer & Composites · Vol. 14, Issue 2, 2026 · pp. 144–157 Read article
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Development and Performance Evaluation of Polymer-Modified Geopolymer Composites Incorporating GGBS
Abstract: This research investigates the development and performance of geopolymer-based composite materials formulated using Ground Granulated Blast Furnace Slag (GGBS) as a reactive mineral component within an aluminosilicate polymer matrix. The study aims to create an eco-efficient and structurally sound inorganic polymer composite comparable to M35-grade concrete, produced entirely under ambient curing conditions. A series of mixes with varying GGBS replacement ratios (0–100%) was prepared, maintaining a constant binder content of …
Published in Journal of Polymer & Composites · Vol. 14, Issue 2, 2026 · pp. 1145–1165 Read article
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Synthesis of Glass Fiber Reinforced Polymer Composites Incorporating MWCNTS and Graphene: A Study on Dynamic Mechanical Behavior and Cole–Cole Representation
Abstract: Glass fiber reinforced polymer (GFRP) composites were fabricated using multi-walled carbon nanotubes (MWCNTs) and graphene as nanofillers through the hand lay-up technique. Two sets of composites were prepared by incorporating MWCNTs and graphene separately into the epoxy resin matrix at varying weight percentages (2%, 4%, 6%, 8%, and 10%). Mechanical and viscoelastic properties were evaluated following ASTM standards, and Dynamic Mechanical Analysis (DMA) was performed to study their mechanical and …
Published in Journal of Polymer & Composites · Vol. 14, Issue 2, 2026 · pp. 1411–1403 Read article
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Bacteria on Salt Water Medium Evaluation: The Conceptual Impacts of Temperature
Abstract: The potential impact of temperature on bacteria on salt water medium for crude oil degradation in an aerated lagoon system was simulated using MATLAB Simulation software. The specific rate of bacteria obtained revealed maximum at temperature of less than 35oC with the order of 90 o C (11 cfu/ml) > 60 o C (40 cfu/ml) > 45 o C (35 cfu/ml) > 30 o C (28 cfu/ml). Most of the …
Published in Research and Reviews : A Journal of Biotechnology · Vol. 16, Issue 1, 2026 Read article
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Effect of Thermal Conditions on Microstructure and Mechanical Properties of AA5083 Processed by Equal Channel Angular Pressing
Abstract: A commercial AA5083 with an initial grain size of 210 μm was given an ultrafine-grained structure using the equal channel angular pressing (ECAP) technique under die design as patented. The identical sample underwent two successful passes through the die at 473 K, with each passage causing the sample to rotate 90° along its own longitudinal axis. After just one pressing, the microstructure was comparatively homogeneous. It was made up of …
Published in Journal of Experimental & Applied Mechanics · Vol. 17, Issue 1, 2026 · pp. 49–64 Read article
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Effect of Red Mud Loading on the Thermal and Mechanical Performance of Polypropylene Composites
Abstract: Waste red mud (RM) serves as a low-cost and sustainable filler material in a polypropylene (PP) matrix. This study investigate the effects of different red mud contents on the dynamic mechanical and thermal properties of polypropylene-red mud (RM-PP) composites where red mud levels range from 0% to 40% (based on weight percentage). Fourier Transform Infrared Spectroscopy (FTIR) was conducted for verifying the presence of both polypropylene and red mud in …
Published in Journal of Polymer & Composites · Vol. 14, Issue 3, 2026 · pp. 161–169 Read article
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AI-Integrated Graphene-Modified Polymer Interfaces for Real-Time Crack Detection and Autonomous Healing in Smart Concrete Structures
Abstract: This study presents the design and development of a graphene-reinforced multifunctional polymer composite interface engineered for structural reinforcement, self-sensing, and autonomous healing applications in cementitious systems. A thermosetting polymer matrix embedded with graphene nanoplatelets (0.25–1.5 wt.%) was developed to establish a conductive polymer nano-composite network. Electrical characterization confirmed a distinct percolation threshold at ~0.6–0.8 wt.%, beyond which a sharp increase in conductivity was observed due to the formation of interconnected …
Published in Journal of Polymer & Composites · Vol. 14, Issue 3, 2026 · pp. 30–42 Read article
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Evaluation of Anti-cataract Potential of Carbocisteine by Using In Vitro Goat Lens Model
Abstract: This study includes Carbocisteine has four Oxygen molecules, one Sulfur molecule, and one Nitrogen molecule. Goat eyeballs were used in the present study. They were obtained from the slaughterhouse. Glucose at a concentration of 55 mM was used to induce cataracts; glucose (5.5 mM) concentration served as a normal control, and Ascorbic Acid served as a standard control. Incubation of lenses with glucose 55 mM showed opacification starting after 8 …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 16, Issue 2, 2026 Read article
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Experimental and Polynomial Regression Modelling of Tensile Characteristics of Hybrid Jute/Hemp Fiber Composites
Abstract: The present study aims to develop hybrid jute-hemp fiber/epoxy composites by the hand lay-up process with 60% of fiber reinforcement and 40 % of matrix ratio. To measure the change of tensile properties, prepared hybrid composites were tested for normal tensile strength and edge notch tensile (ENT) test as per the ASTM standards. Findings show that, developed composites with reported tensile strength followed by comparing it with fracture toughness. Experimentally, …
Published in Journal of Polymer & Composites · Vol. 14, Issue 3, 2026 · pp. 47–58 Read article
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Prime Editing and Base Editing in Human Hematopoietic Stem Cells Toward Scarless Correction of Monogenic Blood Disorders
Abstract: Monogenic hematological disorders – such as sickle cell disease (SCD), β-thalassemia, and X-linked chronic granulomatous disease (X-CGD) – affect >400, 000 newborns worldwide each year, with a considerable burden in low-resource settings . Although donor-derived allogeneic hematopoietic stem-cell transplantation (HSCT) is widely regarded as curative, its application is limited due to issues of donor availability and graft-versus-host disease (GVHD) and conditioning-related toxicity. DSB-based conventional CRISPR-Cas9 strategies are limited by inefficient …
Published in International Journal of Genetic Modifications and Recombinations · Vol. 4, Issue 1, 2026 Read article
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Academic Performance and Its Associated Factors Among Pawe Health Science College Students in Benishangul-Gumuz Regional State, North-West Ethiopia
Abstract: Background: Academic performance can be defined as the degree to which a teacher, an institution, or a student meets short-term or long-term learning objectives. Continuous assessments and the student’s overall cumulative grade point average (CGPA) are typically used to measure academic achievement. Objectives: To assess academic performance and its associated factors among students, in the case of Pawi Health Science College, Benishangul-Gumuz Regional State, North-West Ethiopia, 2025. Methods: An institution-based …
Published in Journal of Nursing Science & Practice · Vol. 16, Issue 1, 2026 · pp. 24–35 Read article