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708 articles for “case study”
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The Evolution of Asthma Management: A Comprehensive Analysis of GINA 2024 Guidelines, Endotype-Driven Diagnosis, and Targeted Biologic Intervention
Abstract: Asthma remains a substantial global public health challenge, characterized by heterogeneous airway inflammation leading to variable airflow obstruction. Recent advances in personalized medicine and guideline revisions, notably the Global Initiative for Asthma (GINA) 2024 update, mandate a profound paradigm shift from reliance on short-acting beta2-agonists (SABA) to antiinflammatory reliever (AIR) strategies utilizing inhaled corticosteroid (ICS)-formoterol. This report provides an exhaustive analysis of current asthma epidemiology, molecular pathogenesis distinguishing between Type …
Published in Recent Trends in Infectious Diseases · Vol. 3, Issue 2, 2026 Read article
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Urban Planning and Design Approaches for Redevelopment: Case of Indian Railway Stations Redevelopment
Abstract: Urban society’s spatial and functional needs are reflected in the theories that revolve around planning and design. These theories evolve and shape urban policies that are the frameworks for the future. The practice of these theories differs across the world because of the unique history and geography of urban areas. However, theories encompass a wide range of subjects that occur repeatedly. It is important to understand and contextualise the theoretical …
Published in International Journal of Urban Design and Development · Vol. 4, Issue 2, 2026 · pp. 25–35 Read article
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Framework-Based Optimization of Catalysis Efficiency through Reaction Pathway Engineering
Abstract: The rational design of heterogeneous catalysts through framework-based approaches has emerged as a transformative strategy for controlling reaction pathways and enhancing catalytic efficiency. This paper examines recent advances in the optimization of catalytic performance through engineered frameworks, including metal-organic frameworks (MOFs), zeolites, and related porous materials. By integrating computational methods with experimental validation, researchers have achieved unprecedented control overactive site architecture, reactant confinement, and elementary reaction steps. This work reviews …
Published in Emerging Trends in Chemical Engineering · Vol. 13, Issue 2, 2026 · pp. 88–99 Read article
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Linear Programming for Profit Optimization in Small-Scale Manufacturing: A Python-Based Simplex and Machine Learning Approach
Abstract: Profit maximization under resource constraints is a classic challenge. Small manufacturers face tight margins and scarce capital every day. This paper tackles that problem using four Python-based methods. The case study is Bintang Bakery in Bandar Lampung, Indonesia. The bakery makes three bread types and faces 18 resource constraints. Data comes from Anggoro et al. Methods tested include LP revised simplex, Differential Evolution, PSO, and ANN Surrogate. General-purpose scipy minimizers …
Published in Research & Reviews : Journal of Statistics · Vol. 15, Issue 2, 2026 · pp. 01–12 Read article
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Research Paper A Review of Symmetry in Mechanical Systems: Theoretical Systems Foundations and Engineering Applications
Abstract: In mechanical system analysis and design, symmetry is of mechanical systems. This article examines the idea of symmetry in mechanical systems, exploring its mathematical foundations (such as Lie algebras and group theory) and how these ideas help explain the behavior, stability, and control of the system. We explore the applications of symmetry in a range of mechanical systems, from basic mechanical connections to intricate multi-body dynamics, emphasizing the benefits of …
Published in Emerging Trends in Symmetry · Vol. 1, Issue 1, 2025 · pp. 15–19 Read article
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Host Invasion to Immune Evasion: Emerging Concepts in Pathogen Virulence Strategies
Abstract: The interaction between hosts and pathogens represents a continuous evolutionary struggle, shaping both microbial virulence and host immunity. Pathogens employ diverse strategies to evade immune surveillance, ranging from antigenic variation and molecular mimicry to hijacking of host immune checkpoints. Simultaneously, hosts refine innate and adaptive immune mechanisms to counteract infection and limit damage. This reciprocal adaptation, known as host–pathogen coevolution, influences pathogen persistence, transmission, and fitness, while also sculpting immune …
Published in International Journal of Pathogens · Vol. 3, Issue 1, 2026 Read article
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Spectral Intuitionistic Fuzzy Hypergraph Operators and Dominance Kernels for Resilient Discrete Network Design
Abstract: A new discrete-mathematical framework is developed for resilient network design on intuitionistic fuzzy hypergraphs, where uncertainty is explicitly represented through membership, non-membership, and hesitation degrees associated with both vertices and hyperedges. These three components are systematically integrated into an effective incidence operator that captures the underlying uncertain relationships within complex hypergraph structures. Based on this operator, both un-normalised and normalized Laplacian matrices are formulated to characterize the spectral properties and …
Published in Recent Trends in Mathematics · Vol. 3, Issue 2, 2026 · pp. 41–48 Read article
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Pelvic Floor Muscle Strengthening in Antenatal Period Among Primigravida Cases at Jorhat, Assam
Abstract: Aim: The study aimed to evaluate the effectiveness of pelvic floor muscle (PFM) strengthening exercises during the antenatal period among primigravida women in Jorhat, Assam, with a focus on improving pelvic floor muscle strength and its impact on pregnancy outcomes. Purpose: To assess whether pelvic floor muscle exercises (specifically Kegel exercises) can enhance PFM strength in pregnant women, using the Modified Oxford Grading Scale (MOS), and to compare these effects …
Published in International Journal of Midwifery Nursing And Practices · Vol. 3, Issue 1, 2025 · pp. 35–42 Read article
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Exploring the Genetic and Environmental Factors Contributing to Ovarian Cancer in Women in Mumbai, India
Abstract: Background: Ovarian cancer incidence in Mumbai has risen by 30% over the past decade, with an age-standardized rate of 9.1 per 100,000 women, contrasting stable trends in Western nations. This study investigates the interplay of genetic and environmental factors driving this disparity in Mumbai’s diverse population. Methods: A hospital-based case-control study was conducted at a hospital, enrolling 200 epithelial ovarian cancer cases (aged 30–70 years) and 400 age-matched controls. Germline …
Published in Research and Reviews: Journal of Oncology and Hematology · Vol. 14, Issue 3, 2025 · pp. 12–17 Read article
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A Study of Open-source Cloud Computing Platforms
Abstract: Cloud computing has modernized the way organizations manage, store, and process data, offering scalable and cost-effective solutions. Open-source cloud computing platforms have emerged as a key enabler in this transformation, providing flexibility, transparency, and community-driven innovation. This study discusses the most prominent open-source cloud platforms, including OpenStack, CloudStack, and Kubernetes, highlighting their architecture, features, and use cases. The study deals with their comparative strengths, limitations, and adoption challenges in various …
Published in Journal of Open Source Developments · Vol. 12, Issue 1, 2025 · pp. 25–36 Read article
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Evaluating the Role of Apple Cider Vinegar in Managing Semaglutide-Induced Gastrointestinal Disturbances: A Systematic Review
Abstract: Background: Semaglutide, a glucagon-like peptide-1 (GLP-1) receptor agonist, is highly effective in treating type 2 diabetes and obesity. However, its use is often associated with gastrointestinal side effects, including nausea, vomiting, and diarrhea, which may impact patient compliance. Objective: This systematic review aims to evaluate the evidence regarding the management of semaglutide-induced GI symptoms and assess the potential role of apple cider vinegar (ACV) as a complementary treatment. Methods: A …
Published in Research and Reviews: A Journal of Medicine · Vol. 15, Issue 1, 2025 · pp. 25–31 Read article
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Timestamp Extraction and Log Classification Using Supervised Machine Learning: A Comparative Study
Abstract: In modern software systems, logs are vital for monitoring application behavior, diagnosing issues, and analyzing performance. Timestamps are especially important for sequencing events, identifying anomalies, and understanding system failures. However, detecting timestamps in logs is challenging due to inconsistent formatting across systems and the presence of timestamp-like strings in non-timestamp fields. Traditional rule-based methods often fail in such cases. This study proposes a supervised machine learning approach to accurately classify …
Published in Journal of Software Engineering Tools & Technology Trends · Vol. 12, Issue 3, 2025 · pp. 26–38 Read article
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The Role of Generative AI in Enhancing Administrative Efficiency: Innovations in Workforce Support Systems
Abstract: Generating AI is the primary form of artificial intelligence that disrupts administrative work across multiple industries by redesigning and promoting the automation of traditional tasks and improving the workforce efficiency of decision-making. In a conventional setting, executive positions have been equally associated with paper-bound responsibilities, common with tedious activities like appointment making, filing, data input, etc. However, improvement in the area of generative AI makes these natural functions assignable, thus …
Published in Journal of Artificial Intelligence Research & Advances · Vol. 12, Issue 1, 2025 · pp. 47–68 Read article
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Evaluating the Role of Platelet Indices, with a Focus on Immature Platelet Fraction (IPF), in Differentiating Hyper-Destructive and Hypo-Productive Thrombocytopenia: A Study from Ludhiana, Punjab, India
Abstract: Background: Thrombocytopenia, characterized by a reduction in platelet count, is commonly observed in clinical settings. Its etiology can be broadly classified into hyper-destructive thrombocytopenia, where platelets are destroyed at an accelerated rate, and hypo-productive thrombocytopenia, where platelet production is impaired. Differentiating between these two causes is essential for effective management. The Immature Platelet Fraction (IPF) has emerged as a promising non-invasive diagnostic tool to distinguish these causes. Objectives: The primary …
Published in Research and Reviews: Journal of Oncology and Hematology · Vol. 14, Issue 2, 2025 Read article
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Nature-Integrated Day-Care Spaces: Fostering Early Childhood Growth in Lucknow
Abstract: The physical environment plays a vital role in shaping early childhood experiences, influencing cognitive, emotional, and social development. However, in rapidly urbanizing cities such as Lucknow, children’s exposure to natural environments has become increasingly limited, with most day-care centers confined within enclosed, concrete settings. This study investigates how the integration of natural elements within day-care interiors and outdoor spaces can foster holistic child development and enhance learning outcomes. Emphasizing the …
Published in International Journal of Architectural Design and Planning · Vol. 4, Issue 1, 2026 · pp. 7–18 Read article
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Associations of C-RP with Renal Function Group and some Clinical Parameters in Patients with Dialysis in Iraq
Abstract: Introduction: Chronic kidney disease is a disease for which there are high mortality rates among those infected with many complications, including high rates of inflammation, anaemia, osteoporosis, and other complications. Methods: The current study was designed to evaluate the kidney functions of patients undergoing dialysis, where levels were evaluated Urea, Uric Acid, and Creatinine, in addition to C-Reactive Protein as a progressive of inflammation parameter, and to evaluate anaemia levels …
Published in International Journal of Biochemistry and Biomolecule Research · Vol. 4, Issue 1, 2026 Read article
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An Evaluative Comparison of CD123 and CD66c as Biomarkers to Detect Minimal Residual Disease in B-Cell Acute Lymphoblastic Leukemia
Abstract: Background: B-cell Acute Lymphoblastic Leukemia (B-ALL) often shows lineage heterogeneity with lymphoid cells expressing myeloid markers. Minimal Residual Disease (MRD) refers to the small number of cancer cells that may remain in a patient's body after treatment and that are undetectable by standard diagnostic methods. In diseases like B-cell Acute Lymphoblastic Leukemia (B-ALL), MRD is a critical prognostic indicator, as its presence can signal a higher risk of relapse. In …
Published in Research and Reviews : A Journal of Medical Science and Technology · Vol. 13, Issue 3, 2024 · pp. 7–12 Read article
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Optimizing Anesthesia for Major Surgery: The Role of Sequential Combined Spinal-Epidural Technique
Abstract: The Combined Spinal Epidural (CSE) approach has been widely employed over the last decade because it achieves rapid onset and substantial blockage while also allowing for the modification or prolongation of the block. Background: Sequential spinal-epidural anesthesia (SSEA) combines the rapid onset and dense blockade of spinal anesthesia with the prolonged duration and adjustable analgesia of epidural anesthesia. This technique is particularly beneficial in major surgeries requiring prolonged operative time …
Published in Research and Reviews : Journal of Surgery · Vol. 14, Issue 2, 2025 · pp. 12–18 Read article
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A Comprehensive Review of Compressed-Air Vehicles: A Technological Advancement Towards Sustainable Development
Abstract: Greenhouse gas emissions have become an essential environmental issue with far-reaching effects on ecosystems and societies worldwide. Around 20-30% of air pollution is caused by harmful gas emissions, mostly by automotive vehicles. The consumption of fossil fuels in vehicles and other utilities is responsible for the depletion of natural resources. The excessive use of fossil fuels has increased energy costs and intensified competition for different resources, posing economic issues in …
Published in Journal of Polymer & Composites · Vol. 13, Issue 5, 2025 · pp. 567–588 Read article
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Personalised Cancer Vaccination Strategies: Bridging Genomics, Bioinformatics, and Immunotherapy
Abstract: Immunotherapy has revolutionized cancer treatment by harnessing the body’s immune system to detect and destroy cancer cells. Personalised cancer vaccines are one of the most promising options because they could allow treatment to be based on the specific tumour profile of each person. The goal of these vaccines is to make the immune system recognise and fight cancer-specific antigens, which will lead to strong and long-lasting anti-tumor responses. However, moving …
Published in Research and Reviews : A Journal of Immunology · Vol. 15, Issue 3, 2025 Read article