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469 articles for “Medicinal uses”
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Novel 1,3,4-Thiadiazole Derivatives: Design, Synthesis, Characterization and Anticancer Evaluation – A Review
Abstract: Cancer remains one of the leading causes of mortality worldwide despite significant advances in diagnosis and treatment. The clinical usefulness of many anticancer drugs is often restricted by toxicity, poor selectivity, and the emergence of drug resistance. These limitations have encouraged the search for novel heterocyclic compounds with improved therapeutic efficacy and safety. Among these, the 1,3,4-thiadiazole scaffold has gained considerable attention because of its favorable physicochemical characteristics, metabolic stability, …
Published in Research & Reviews: A Journal of Drug Design & Discovery · Vol. 13, Issue 2, 2026 Read article
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In Silico Assessment of Demethoxycurcumin: Molecular Docking and Computational Insights into its various therapeutic Potential
Abstract: Natural compounds are increasingly explored for their therapeutic potential in medical research. Here, we focused on demethoxycurcumin (DMC), a polyphenolic bioactive compound extracted from Curcuma longa, commonly found in turmeric. DMC, with a chemical formula of C20H18O5 and a molecular weight of 340 g/mol, possesses two aromatic ring systems, each featuring a β-diketone moiety connected by a seven-carbon chain. This unique structure allows DMC to engage in tautomerism, which is …
Published in Research & Reviews: A Journal of Drug Design & Discovery · Vol. 11, Issue 1, 2024 · pp. 9–15 Read article
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Phytochemical profiling and LC/MS analysis of Selaginella bryopteris (L.) Baker
Abstract: Selaginella bryopteris (L.) Baker, an endemic pteridophyte is found restricted to the Indian subcontinent mostly because of its environmental requirements of cool temperatures and optimum water availability. It is a drought-resistant species and shows curling in limited water supply reviving when water conditions are restored. This property makes this species a suitable plant for exploration of medicinal properties, although its restricted occurrence has limited this evaluation. The current study explores …
Published in Research & Reviews : Journal of Herbal Science · Vol. 14, Issue 1, 2025 · pp. 46–51 Read article
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In Silico Exploration of Podophyllum Hexandrum-Derived Phytocompounds as Potential Therapeutics Against Small Cell Lung Cancer (SCLC): A Molecular Docking Approach
Abstract: Small Cell Lung Cancer (SCLC) is a fast-growing and aggressive type of lung cancer that spreads quickly strongly associated with smoking. It is characterized by symptoms, such as persistent cough, breathing difficulties, or hoarseness, though it can sometimes be asymptomatic which makes early detection challenging. The tumor suppressor gene TP53 is critical in regulating the cell cycle and preventing uncontrolled cell division. Mutations in TP53 result in the loss of …
Published in International Journal of Molecular Biotechnological Research · Vol. 3, Issue 1, 2025 · pp. 1–11 Read article
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Detecting Fake Images with Python: A Simple Approach Using OpenCV and MD5
Abstract: In today’s modern era, ensuring the authenticity of pictures is crucial. This article presents a straightforward method for identifying fake pictures using the widely used OpenCV and MD5 technologies. OpenCV helps us examine pictures for irregularities such as abnormal colors or shapes, while MD5 is a unique digital fingerprint for each image. Our approach combines these tools to create a robust fraud detection system. OpenCV carefully examines various aspects of …
Published in Journal of Operating Systems Development & Trends · Vol. 11, Issue 1, 2024 · pp. 45–49 Read article
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Phytomedicine in 21st century: challenges, innovations & future directions
Abstract: Phytomedicine, the use of plant-derived substances for therapeutic purposes, has experienced significant advancements and challenges in the 21st century. This review explores the current state of phytomedicine, highlighting its advantages, such as natural ingredients, fewer side effects, and cultural acceptance, as well as its disadvantages, including variable quality, lack of standardization, and limited research. The challenges faced by phytomedicine are discussed, focusing on issues of standardization, regulatory discrepancies, scientific evidence …
Published in International Journal of Tropical Medicines · Vol. 2, Issue 1, 2025 · pp. 86–95 Read article
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Phytochemicals from Plectranthus amboinicus and Azadirachta indica for Promoting Angiogenesis and Tissue Regeneration – A Short Review
Abstract: The eco-friendly synthesis of silver nanoparticles (AgNPs) using plant extracts has garnered significant attention due to its potential in biomedical applications. This review highlights the green synthesis methodologies, focusing on Plectranthus amboinicus and Azadirachta indica, their phytochemical components, and their docking studies with angiogenesis-related receptors such as VEGF and FGF. The applications of AgNPs in tissue regeneration, wound healing, and angiogenesis are discussed in detail, emphasizing the roles of phytochemicals …
Published in Nano Trends – A Journal of Nano Technology & Its Applications · Vol. 27, Issue 2, 2025 · pp. 34–40 Read article
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Preparation, Categorization and Anticancer Study of Novel Bicyclic Compounds from Various Types for (Five and Six)- Membered Ring
Abstract: The characteristics of ring systems change in the presence of functional groups, but in some cases, elements that are considered functional groups can be classified within the same ring. Compounds that contain only carbon and hydrogen are called homogeneous rings, while those that contain other elements are called heterogeneous rings. The atom substituted in place of the carbon atom is referred to as a heteroatom. Generally, the heterocyclic atom is …
Published in Journal of Catalyst & Catalysis · Vol. 12, Issue 3, 2025 · pp. 18–30 Read article
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Advances in Biopolymer-Based Surgical Implants: A Polymer Chemistry Perspective
Abstract: Biopolymers have emerged as a promising class of materials for surgical implants due to their biocompatibility, biodegradability, and ability to mimic natural tissue properties. These materials play a crucial role in modern biomedical engineering by reducing adverse immune responses and enhancing tissue integration. This paper explores the role of polymer chemistry in developing biopolymer-based surgical implants, highlighting key polymeric materials. These polymers are making them suitable for diverse biomedical applications. …
Published in Journal of Polymer & Composites · Vol. 13, Issue 6, 2025 · pp. 1–6 Read article
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Scholarly Communications of Annamalai University on Web of Science in Global Perspective: A Scientometric Assessment
Abstract: Annamalai University has a prolific research output spanning various fields such as agriculture, medicine, engineering, humanities, and social sciences. With state-of-the-art facilities and dedicated faculty, the university consistently produces impactful research findings that contribute to advancements in knowledge and address societal challenges. Its research endeavors are characterized by innovation, interdisciplinary collaboration, and a commitment to excellence, making Annamalai University a significant hub for cutting-edge research in India and beyond. The …
Published in Journal of Advancements in Library Sciences · Vol. 12, Issue 3, 2025 · pp. 1–10 Read article
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Implementing Quality by Design (QbD): Strategies, Challenges, and Best Practices across Industries
Abstract: The present comprehensive review investigated the dynamic landscape of quality standards within the pharmaceutical sector, with a primary focus on the implementation and impact of Quality by Design principles. It illuminated the multifaceted challenges encountered by pharmaceutical companies in upholding stringent quality standards amidst evolving regulatory requirements and complex manufacturing processes. By embracing Quality by Design principles, the industry aims to foster a proactive and systematic approach to product development …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 15, Issue 2, 2024 · pp. 28–36 Read article
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Vedic Chemical Insights as Precursors to Modern Green and Sustainable Chemistry: An SDGAligned Perspective
Abstract: This paper explores the chemical insights found in ancient Vedic texts and their relevance to contemporary green and sustainable chemistry. It examines the alchemical traditions described in Vedic literature, such as Rasaśāstra, which integrate material and spiritual aspects of transformation. The study investigates how ancient chemical processes align with modern principles of green chemistry, including waste reduction, use of renewable resources, and energy efficiency. By analyzing the parallels between Vedic …
Published in Emerging Trends in Chemical Engineering · Vol. 13, Issue 1, 2026 · pp. 36–48 Read article
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Revealing the Hemodynamic Orchestra: Contrasting Analysis of Blood Flow Patterns in a Bifurcated Carotid Artery
Abstract: Understanding blood flow patterns in the carotid artery (CA) is crucial for detecting cardiovascular diseases. Computational fluid dynamics simulations compared non-Newtonian (non-Newt) and Newtonian (Newt) models under pulsatile and laminar flow. CA geometry was accurately designed using ANSYS Space Claim & Fusion360, and simulations were run in ANSYS Fluent. Discrepancies between non-Newt and Newt models were found, especially in bifurcation's distal regions prone to plaque. Pressure ranged from 27.870 Pa …
Published in Journal of Polymer & Composites · Vol. 11, Issue 13, 2023 · pp. 229–247 Read article
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Enhancing the User Experience of Asthma Inhalers: A Redesign Approach
Abstract: Asthma is a widespread chronic respiratory condition impacting millions globally, presenting significant challenges in its management and treatment. While conventional inhalers effectively administer medication, they often encounter usability issues, hindering patient adherence and treatment outcomes. This abstract delineates the development and potential impact of a redesigned asthma inhaler aimed at addressing these challenges. Incorporating human-centered design principles, the revamped inhaler prioritizes usability, portability, and effectiveness to enhance the overall management …
Published in International Journal of Solid State Innovations & Research · Vol. 1, Issue 2, 2023 · pp. 32–36 Read article
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Diabetes Risk Prediction from Survey Data Using Machine Learning Algorithms
Abstract: Diabetes mellitus represents one of the most significant global health challenges, affecting millions worldwide and leading to severe complications if left undiagnosed or poorly managed. Early detection and risk assessment are crucial for preventing the progression of this chronic condition. This research presents a comprehensive machine learning approach for predicting diabetes risk using survey-based health parameters. The study implements and compares four prominent classification algorithms: Logistic Regression, K-Nearest Neighbors (KNN), …
Published in International Journal of Bioinformatics and Computational Biology · Vol. 4, Issue 2, 2026 Read article
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Rethinking Type-1 Diabetes Treatment: Emerging Medicines Based on AAT Therapy and C-peptide Preservation Therapy
Abstract: The increasing number of cases, especially in the younger age group, along with the lack of accessible clinical solutions, make Type-1 Diabetes (T1D) a growing global health concern. While gene therapy and transplantation approaches are promising avenues, their excessively high costs and logistical difficulties make them inaccessible to the majority and can impose a financial burden on those suffering from it, adding to the challenges already faced by these advanced …
Published in Research and Reviews : A Journal of Life Sciences · Vol. 14, Issue 3, 2024 · pp. 19–29 Read article
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Integrative Perspectives on Lipoma: Traditional Therapeutics from Siddha, Ayurveda, and Unani with Biomedical Correlates
Abstract: Background: Lipoma is the most common benign soft tissue tumor, with an incidence of approximately 2 per 1,000 individuals annually. Modern biomedicine attributes its pathogenesis to genetic abnormalities like HMGA2 rearrangements and dysregulated adipogenesis via PPARγ pathways. Effective pharmacological therapies are lacking. Traditional Indian systems – Siddha, Ayurveda, and Unani – offer unique perspectives and non‑surgical approaches yet remain underexplored in integrative research. Objective: To critically evaluate the descriptions, pathophysiological …
Published in Research & Reviews : A Journal of Unani, Siddha and Homeopathy · Vol. 13, Issue 1, 2026 · pp. 19–33 Read article
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Systematic Review on: Peptic Ulcer and Its Management
Abstract: Peptic ulcer disease (PUD), which affects 5–10% of people worldwide, is still a significant global health concern. Gastric acid and pepsin's corrosive effects cause mucosal injury in the stomach, duodenum, or lower oesophagus. Long-term use of nonsteroidal anti-inflammatory drugs (NSAIDs) and Helicobacter pylori infection are the primary reasons. This review's goal is to examine PUD's aetiology, risk factors, pathophysiology, clinical symptoms, diagnostic methods, and evidence-based treatment modalities. PubMed, Google Scholar, …
Published in Research and Reviews : A Journal of Life Sciences · Vol. 16, Issue 1, 2026 Read article
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Standard Manufacturing Procedure (SMP) of Jaharamohara Bhasma Prepared by two Methods
Abstract: Introduction: Jaharamohara (Serpentine) is an important drug of Ayurveda and Unani medicine. In the literature of Rasashastra it is classified under Sikta Varga (group of silica containing drugs). In classical texts, different Bhavana Dravya (levigating material) are advised for the preparation of Jaharamohara Bhasma which enhances its potency. However, no work has been done till date to standardize Jaharamohara Bhasma by two different methods. Aim: An attempt has been made …
Published in Research and Reviews : A Journal of Ayurvedic Science, Yoga and Naturopathy · Vol. 11, Issue 1, 2024 · pp. 1–13 Read article
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Computational Exploration of Bhrijraj-derived Phytochemicals as Potential Anti-inflammatory Agents: A Molecular Docking Study with Cyclooxygenase-II Complex
Abstract: The molecular docking analysis was meticulously conducted using state-of-the-art computational tools, notably Chimera and Python. These tools were employed to unravel the complex interactions between the identified phytochemicals from Bhrijraj and the target protein, COX-II. The 3D structures of the phytochemicals were prepared with precision using ChemSketch, ensuring accuracy in the subsequent molecular docking simulations. This rigorous approach enhances the reliability and validity of the findings. This research aims to …
Published in Research and Reviews : Journal of Computational Biology · Vol. 13, Issue 1, 2024 · pp. 31–37 Read article