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1068 articles for “disease”
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Next-Generation mRNA Vaccines: Applications Beyond COVID-19
Abstract: Messenger RNA (mRNA) vaccine technology has become a paradigm shift in contemporary medicine and, with remarkable success in the COVID-19 pandemic, has opened the door to a new wave of vaccines development. In contrast to the traditional vaccine methods, mRNA vaccines are based on the synthetic genetic code that allows host cells to express target antigens, thus eliciting strong humoral and cellular immunity. The speed of development, efficacy, scalability of …
Published in International Journal of Vaccines · Vol. 3, Issue 2, 2026 · pp. 15–26 Read article
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GenChrome-ML: A Machine Learning Framework for Early Detection of Chromosomal Disorders Using Genomic Data
Abstract: The increasing burden of chronic disease and cancer demands innovative, more rapid and effective diagnostic tools in the field of healthcare. The majority of current diagnostic tools are dependent upon clinical symptomology and manual evaluation, leading to delays in early detection and treatment. The development of artificial intelligence (AI) and machine learning (ML), in recent years, has offered opportunities for the enhancement of disease prediction, diagnosis and personalization of treatment …
Published in International Journal of Bioinformatics and Computational Biology · Vol. 4, Issue 2, 2026 Read article
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DEVELOPMENT OF POLYMERSOMES AS MACROMOLECULAR PLATFORMS FOR NANOMEDICINE
Abstract: The conventional method of drug delivery is plagued with instability, low targeting and low bioavailability. A solution to these shortcomings is the use of polymer Somes, artificial vesicles that are produced through self-assembly of amphiphilic block copolymer, and they are suggested as universal nanoscale carriers. They have stiff, tunable membranes (thickness = 2-50 nm) due to accurate control of polymer chemistry, chain length, and hydrophilic mass fraction (f), which allows …
Published in Journal of Polymer & Composites · Vol. 14, Issue 5, 2026 Read article
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Psoriasis: Latest Trends in Treatment, Diagnosis and Management in Medical Science
Abstract: Psoriasis is a common chronic inflammatory and autoimmune skin disease that primarily affects the skin. It affects about 2–4% of the world populations. It is clinically characterized by skin rashes, highly inflamed red scale itchy plaque. Abundant therapeutic agents are accessible for the treatment of psoriasis. Wide range of therapeutic mediators such as coal tar, topical corticosteroids, anthralin, retinoid, calcineurin inhibitors, methotrexate, cyclosporine are proven to be effective in treating …
Published in Research and Reviews : A Journal of Biotechnology Read article
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Concept and Management of Haemorrhoids (Bawaseer) in Unani System of Medicine
Abstract: Haemorrhoids are one of the most prevalent diseases with significant impact on quality of life. Haemorrhoids commonly known as piles are defined as swollen, inflammed veins around the anus or the lower part of rectum. The most common symptom of haemorrhoids is rectal bleeding and discomfort before or after bowel movements. According to the Unani Physicians, the most common cause of the haemorrhoids is the accumulation of the abnormal melancholic …
Published in Research & Reviews : A Journal of Unani, Siddha and Homeopathy Read article
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A Comprehensive Review on Adiantum Incisum (Maidenhair)
Abstract: A traditional medicinal maidenhair fern Adiantum incisum member of pteridaceae family widely distributed in hilly areas has been reported for its traditional uses as a medicinal fern. The presence of active nutrients and their multifunctional roles make Adiantum spp. leaves perfect candidates for the production of phyto-pharmaceutical products. It is used traditionally as remedy in different disease conditions like diabetes, inflammation, skin disease, liver disorder, fever etc. It is important …
Published in Research & Reviews: A Journal of Drug Formulation, Development and Production · Vol. 8, Issue 3, 2023 · pp. 1–8 Read article
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A Structure-based Design Approach to Catharanthus roseus Phytoconstituents as Potential Inhibitors of B-Cell Lymphoma 6 Protein
Abstract: Objectives: Lymphoma is a cancerous disease. It develops into millions of people worldwide. Identify the naturally active compounds from Catharanthus roseus, they have multiple values in the medicinal field of Siddha, and Indian Ayurveda are used as a disease-preventing agent. Drug illness prediction, toxicity prediction, statistical information, molecular docking, as well as absorption, distribution, metabolism, and excretion (ADME) analysis are used to predict the fit ligand as a drug. Methods: …
Published in International Journal of Bioinformatics and Computational Biology · Vol. 1, Issue 2, 2023 · pp. 14–34 Read article
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Tinospora Sinensis Compounds for Zika Virus Targets 5JRZ and 5KVD In Silico Screening: A Potential Approach to Preventing Guillain-Barre Syndrome
Abstract: Objective: GBS is a very rare kind of disease but at the same time, it is very dangerous too. The study estimates that people who are suffering from zika virus infection are more prone to GBS. According to surveys, 1 out of 4000 people got affected by this disease, and the scariest part of this disease is that there is no cure available. In this computational era drug discovery is …
Published in International Journal of Cell Biology and Cellular Functions · Vol. 1, Issue 2, 2023 · pp. 1–15 Read article
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Recent Update on Advanced Drug Delivery System
Abstract: Over the past decade, there has been a growing interest in the use of artificial intelligence (AI) technology for analysing and interpreting biological or genetic data, accelerating drug discovery, and identifying selective small-molecule modulators or rare molecules in addition to predicting their behaviour. The use of artificial neural networks (ANNs) for the rapid analysis of massive amounts of data, the development of novel hypotheses and treatment plans, the prediction of …
Published in International Journal of Advance in Molecular Engineering · Vol. 1, Issue 1, 2023 · pp. 22–30 Read article
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A Case Study on Ayurvedic Management of Psoriasis.
Abstract: Psoriasis is non-contagious, chronic autoimmune disease which causes inflammation and hyper-proliferation of the skin. It is characterized by erythematous plaques that are clearly defined and associated with severe itching and silvery scaling, especially on extensor surfaces, scalp and nails. At times, it may manifest as localized or generalised pustular eruption which usually follows relapses and remissions pattern. Psoriasis may lead to other autoimmune diseases like psoriatic arthritis. In Ayurveda, Variety …
Published in Journal of AYUSH: Ayurveda, Yoga, Unani, Siddha and Homeopathy · Vol. 13, Issue 1, 2024 · pp. 18–22 Read article
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Molecular Docking and Interaction of Anthocyanin Derivatives in Regulating Hippo-taz Pathway for Renal Injuries
Abstract: Introduction: The Hippo pathway plays a pivotal role in renal disease, with Yes-associated protein (YAP) exhibiting promise for combined treatments. The crucial evaluation of YAP-targeted drug safety and efficacy through preclinical studies is imperative. Additionally, α-SMA and SMAD3 emerge as potential therapeutic targets in renal fibrosis, driving ongoing research toward innovative interventions. Materials and Methods: In the systematic identification of therapeutic secondary metabolites, Anthocyanin derivatives were methodically retrieved from the …
Published in International Journal of Genetic Modifications and Recombinations · Vol. 2, Issue 1, 2024 · pp. 23–38 Read article
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The Emergence of Coxsackievirus A16 Associated with HFMD Colloquially Termed ‘Tomato Flu’ in India 2022: A Detailed Virological Inspection
Abstract: As the world battles the COVID-19 pandemic and grapples with a concerning spike in monkeypox cases, India has encountered another viral illness dubbed "Tomato Flu." Tomato Flu is a viral disease caused by coxsackievirus A16, which is a highly infectious illness affecting children under 10 years old.. Enterovirus A71, CV-A16, CVA6, and echoviruses are the causes of what is also referred to as hand, foot, and mouth disease (HFMD). The …
Published in International Journal of Vaccines · Vol. 1, Issue 1, 2024 · pp. 29–40 Read article
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Nutritional, Preventive, and Therapeutic Potential of Ma-ul-Shae’er (Barley Water) in the Unani System of Medicine: A Holistic Viewpoint
Abstract: In the Unani methodology of managing diseases, Ilaj-bil-Ghiza (dietotherapy) serves as a foundational principle. The initial course of treatment for any ailment entails prescribing specific diets or regulating the quality and quantity of food intake. In recent times, there has been a heightened public awareness regarding the health advantages of functional foods and nutraceuticals for disease prevention and overall well-being. Unani medicine provides a methodical classification of food, taking into …
Published in Research and Reviews: A Journal of Medicine · Vol. 14, Issue 1, 2024 · pp. 18–25 Read article
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Application of Medicinal Plants to Cure Mental Disorders
Abstract: Mental fitness is a state of well-being in which individuals apprehend their talents, manage existing pressures, remain efficient, and contribute to their groups. Mental contamination regularly used interchangeably with intellectual illness, is vital to apprehending and addressing man or woman desires and challenges. Schizophrenia, a psychological disorder characterized by hallucinations and delusions, is a complex situation with two important classes: bad symptoms (withdrawal from social interactions, loss of force, and …
Published in Research and Reviews : A Journal of Biotechnology · Vol. 14, Issue 1, 2024 · pp. 69–78 Read article
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Overview On Lauha Rasayana W.S.R. To Rasayogasagar
Abstract: Ayurved is the ancient science which addresses disorders with the natural pharmaceuticals, including those derived from animals, plants, minerals and metals. Rasashastra is a pharmaceutical branch of Ayurved medicine, which developed in mediaeval period and focuses on therapeutic use of metals and minerals. Treatment with using of this metals, minerals, gemstones, animal product and herbal ingredients is known as Rasachikitsa. The key objective of Rasachikitsa is to deliver high-quality, safe …
Published in Research & Reviews : Journal of Herbal Science · Vol. 13, Issue 1, 2024 · pp. 11–16 Read article
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Nanotechnology’s Emerging Frontiers
Abstract: Nanotechnology holds significant promise across diverse sectors, including agriculture, food processing, energy, transportation, and communication systems. This swiftly evolving domain revolves around the development of groundbreaking materials and devices that tackle intricate engineering and scientific hurdles across various sectors. In agriculture and food processing, nanotechnology unfolds a myriad of potentialities. Its potential extends to the development of various products such as nano-fertilizers, nano-herbicides, nano-pesticides, and nano-scale carriers. Additionally, it plays …
Published in Journal of Petroleum Engineering & Technology · Vol. 14, Issue 1, 2024 · pp. 14–23 Read article
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Clinical experience with Ayurvedic Treatment in Case of Rheumatoid Arthritis – Ayurvedic review and Case study
Abstract: Rheumatoid arthritis is the most found inflammatory auto immune disease with unknown etiology. Many clinical features and treatment strategies of RA are associated with multiple joint diseases. The clinical phenotype of Rhematoid arthritis is a symmetrical, deformed polyarthritis of small and large joints, which is often associated with features of the disease. The treatment typically involves ongoing management with periods of worsening symptoms followed by periods of improvement. Features of …
Published in Research and Reviews : A Journal of Ayurvedic Science, Yoga and Naturopathy · Vol. 11, Issue 2, 2024 · pp. 1–8 Read article
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Universal Immunization Program in India
Abstract: The Universal Immunization Program (UIP) in India, initiated by the Government of India in 1985 and incorporated into the Child Survival and Safe Motherhood Program in 1992, plays a crucial role in enhancing public health through systematic vaccination efforts. This program aims to save lives and strengthen immune systems by administering vaccines and antibiotics. The UIP has spurred the development of various campaigns, including mass media efforts, to promote immunization …
Published in Research and Reviews: A Journal of Microbiology and Virology · Vol. 14, Issue 2, 2024 · pp. 24–30 Read article
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Role of Gastric Receptors in Gastrointestinal Disorder
Abstract: The established and potential roles of cholecystokinin1 and cholecystokinin2 receptors in gastrointestinal and metabolic diseases are analyzed, along with findings from human studies involving agonists and antagonists. While there is considerable evidence implicating cholecystokinin1R in various diseases such as pancreatic disorders, motility disorders, tumor growth, satiety regulation, and cholecystokinin-deficient states, its specific role in these conditions remains ambiguous. Conversely, the role of cholecystokinin2R in physiological (e.g., atrophic gastritis) and pathological …
Published in International Journal of Biomedical Innovations and Engineering · Vol. 2, Issue 2, 2024 · pp. 37–49 Read article
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Netra Roga Nidana : A Critical Review
Abstract: Ayurveda defines Indriyas as sense organs that acquire knowledge for the Atma. According to Acharya Charaka, Indriyas are instruments that distinguish between living and non-living things. Because the Panch Mahabhuta (five elements) contributed to the composition of Indriyas, different sense organs function differently. Indriyas exist in minute form within their Indriya adhishtanas (anatomical organs) and perform the function of perceiving senses and communicating that perception to the brain or body …
Published in Journal of AYUSH: Ayurveda, Yoga, Unani, Siddha and Homeopathy · Vol. 13, Issue 2, 2024 · pp. 48–53 Read article