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837 articles for “Clinical”
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Evaluation of Patient-Specific Quality Assurance for RapidArc Treatment Delivery Using Dose Volume Histogram
Abstract: This study aims to evaluate the application of dose volume histogram (DVH) metrics within the patient-specific quality assurance (PSQA) protocol in various sites for RapidArc treatment delivery. Forty patients were included in this study, of which twenty each Head and Neck (H&N) and Pelvis Rapid Arc plans were evaluated. Octavius 4D 1500 detector array with vented parallel plate ion chambers was used for this study, which reconstruct the pre-treatment measured …
Published in Journal of Polymer & Composites · Vol. 11, Issue 7, 2023 · pp. 14–22 Read article
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Risk & Opportunities in Development of new Drugs: A New Perspective
Abstract: The procedures of drug discovery and development are briefly described in this article. Our goal is to assist researchers whose work may be pertinent to the discovery and/or development of new drugs in framing their research reports in a way that appropriately situates their findings within the drug discovery and development process and supports the efficient translation of preclinical research to humans. One overarching theme of our article is the …
Published in Recent Trends in Infectious Diseases · Vol. 1, Issue 2, 2024 · pp. 19–28 Read article
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Effect of Nebulization With 3% Hypertonic Saline for Airway Clearance on Mechanically Ventilated Patients Admitted in ICUs of Pt. B.D. Sharma, PGIMS, Rohtak
Abstract: Background of the Study: The ability to breathe artificially prolongs life in many situations. Patients requiring mechanical breathing in the intensive care unit are more likely to have complications and even death due to a variety of interconnected causes. As a result, it became critical to rapidly ventilate in the safest and most efficient manner available. Intubated patients have benefited from nebulized suctioning, as it improves lung clearance and decreases …
Published in International Journal of Emergency and Trauma Nursing and Practices · Vol. 1, Issue 2, 2023 · pp. 20–27 Read article
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Pharmacophore mapping, 3D QSAR, docking, and ADME prediction studies of novel Benzothiazinone derivatives
Abstract: Background Tuberculosis is a major public health concern worldwide which is caused by Mycobacterium tuberculosis. DprE1 (Decaprenyl Phosphoryl Ribose 2’- Epimerase) is the most challenging target for development of novel anti- tubercular agents because it is a small protein and located into cytoplasmic membrane. So, novel anti-TB drugs did not bound effectively with it. DprE1 catalyzes the oxidation of the 2’ hydroxyl group of DPR (Decaprenyl Phosphoryl D- Ribose) …
Published in International Journal of Antibiotics · Vol. 1, Issue 1, 2024 · pp. 59–82 Read article
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Recent Update on Advanced Drug Delivery System
Abstract: Over the past decade, there has been a growing interest in the use of artificial intelligence (AI) technology for analysing and interpreting biological or genetic data, accelerating drug discovery, and identifying selective small-molecule modulators or rare molecules in addition to predicting their behaviour. The use of artificial neural networks (ANNs) for the rapid analysis of massive amounts of data, the development of novel hypotheses and treatment plans, the prediction of …
Published in International Journal of Advance in Molecular Engineering · Vol. 1, Issue 1, 2023 · pp. 22–30 Read article
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Managing Carpal Tunnel Syndrome: Insights into Symptoms and Relief
Abstract: Carpal tunnel syndrome (CTS) is a prevalent and concerning issue affecting the wrist and hand, arising from the compression of the median nerve within the carpal tunnel. This compression results in a spectrum of distressing symptoms, including numbness, tingling, weakness, and discomfort, particularly in the thumb, index, and middle fingers. Despite its frequent association with repetitive hand movements and prolonged use of computers or handheld devices, CTS can stem from …
Published in International Journal of Orthopedic Nursing and Practices · Vol. 1, Issue 2, 2023 · pp. 6–12 Read article
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Construction and Standardization of Beauty Satisfaction Scale for Adolescents with Cleft Lip and Palate
Abstract: This study outlines the methodology and findings of a study that aimed to create a tool for assessing adolescents with oral facial clefts’ levels of beauty satisfaction. The development of this tool includes a well-detailed literature survey, focus group discussion with adolescents with oral facial clefts, and the wide process of consultation with the cleft surgeon, orthodontist, pediatrician, and clinical psychologist. Further test construction includes planning of the scale, item …
Published in International Journal of Orthopedic Nursing and Practices · Vol. 1, Issue 2, 2023 · pp. 19–23 Read article
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A Study to Assess the Effectiveness of Home-based Stretching Exercises on Joint Pain Among Clients with Osteoarthritis in Selected Old Age Home, Rajkot City, Gujarat
Abstract: Osteoarthritis (OA) is a commonly encountered condition in middle-aged and older individuals, marked by its slow development. Strengthening exercises targeting the quadriceps muscles, situated in the front thigh, can mitigate knee pain, and reduce disability associated with OA. The musculoskeletal system encompasses the bones of the skeleton, the joints where these bones connect, and the muscles responsible for enabling and regulating movement. The knee, the largest and most complex joint, …
Published in International Journal of Orthopedic Nursing and Practices · Vol. 1, Issue 2, 2023 · pp. 24–28 Read article
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Tools, Modern Drugs, and Latest Investigations for the Diagnosis and Treatment of Heart Failure: A Systematic Review of the General Causes
Abstract: Heart failure (HF) diagnosis and treatment present formidable challenges, given the absence of a definitive single test. This systematic literature review aims to comprehensively analyze the current landscape of diagnostic tools, modern drugs, and latest investigative approaches in HF management. Recognizing the complexity of HF etiology, this systematic review emphasizes the importance of advanced diagnostic methods, such as genetic testing and artificial intelligence applications. The systematic review was conducted to …
Published in Research and Reviews : A Journal of Medical Science and Technology · Vol. 13, Issue 1, 2024 · pp. 1–10 Read article
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Rheumatoid Arthritis and its Relationship with Vitamin D, ESR, and Obesity
Abstract: Recent years have seen a rise in the prevalence of rheumatoid arthritis (RA), a disease marked by the destruction of articular cartilage and ankylosis of the joints, as well as other complications such as diffuse lung inflammation, sclera, pleura, pericardium, and nodular lesions, which are also common in subcutaneous tissue. Reviewing RA symptoms, diagnosis, treatment, and associations with vitamin D, ESR, and obesity was the aim of the study. Even …
Published in International Journal of Toxins and Toxics · Vol. 1, Issue 1, 2024 · pp. 06–12 Read article
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A Review on Nano-emulsion for Delivery of Anti-cancer Drugs
Abstract: Cancer disease is characterized by abnormal cell growth. Malignant growth treatments have progressed significantly, yet there is a requirement for development in particularity and feeling of dread toward foundational harmfulness. Nanotechnology is the reconciliation of nanoscience into medication by the utilization of nanoparticles. The appearance of nanoscience in disease conclusion and treatment will assist clinicians with better surveying and oversee patients and further develop the medical care framework and administrations …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 15, Issue 1, 2024 · pp. 7–13 Read article
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A Rare Case Of Symplastic Leiomyoma Of Uterus : A case Report
Abstract: Uterine smooth muscle tumors (USMT) are of mesenchymal origin and develop from the smooth muscle cells of the uterus. Leiomyomas and their subtypes are the most commonly occurring USMT’s. Symplastic Leiomyoma is an unusual histologic subtype of Benign Leiomyoma, hence also known as atypical or Bizarre leiomyoma. It is often difficult to differentiate it from Leiomyosarcoma because of its bizarre looking nuclei on histology. However it’s malignant transformation is rare. …
Published in International Journal of Toxins and Toxics · Vol. 1, Issue 2, 2024 · pp. 26–31 Read article
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DMARDs, Biologic Agents and Novel Experimental Strategies in The Treatment of Rheumatoid Arthritis
Abstract: An inflammatory and autoimmune disease, rheumatoid arthritis (RA) causes severe pain and inflammation in affected areas of the body. According to the report, there is no known cure for RA. Therefore, reducing discomfort and halting future harm must be the goals of present therapy. For the purpose of prevention and to reduce disease activity in RA patients, significant success has been achieved with the continued development of disease-modifying antirheumatic drugs …
Published in Emerging Trends in Personalized Medicines · Vol. 1, Issue 1, 2024 · pp. 14–24 Read article
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The Use of Autologous Platelet-Rich Plasma in Treating Web Space Scar Contractures in Pediatric Burn Patients
Abstract: Burn injuries are prevalent among children, with scald injuries emerging as the predominant type among those under the age of five, constituting more than 65% of cases. Despite receiving appropriate initial treatment and compressive therapy, deep burns often result in contractures, with web space and hand contractures being the most frequent and functionally limiting.To address these challenges in burn management, Autologous Platelet Rich Plasma (APRP) has emerged as a significant …
Published in Research and Reviews : Journal of Surgery · Vol. 13, Issue 1, 2024 · pp. 1–5 Read article
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Assessment of Diuretic Activity of Hydroalcoholic Extract of Matricaria Chamomilla (Linn.) and Its Phytochemical Analysis with Emphasis on Toxicology
Abstract: While the traditional medicines are derived from medicinal plants, minerals and organic matter, the herbal drugs are prepared from medicinal plants only. This current research work will be very beneficial in figuring out the Matricaria chamomilla leaves extract diuretic effect by determining the ions and electrolyte excreted by the animals using ion selective channel inhibition. The phytochemical screening results revealed that the after which it was observed whether the alkaloids …
Published in Research and Reviews: A Journal of Toxicology · Vol. 14, Issue 1, 2024 · pp. 1–10 Read article
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Deciphering Th-Related Gene Interactions in Chronic Spontaneous Urticaria: Bioinformatics Insights and Drug Affinity Exploration
Abstract: Objective: There has been a great deal of interest in how inflammatory dermatosis and The cell interact, but the etiopathogenesis of chronic spontaneous urticaria (CSU) is still inadequately comprehended. Through bioinformatics techniques, the purpose of this work is to elucdate the molecular mechanism underlying Th-related genes in CSU and seeks to find the highest affinity drug. Methods: The CSU RNA expression profiling dataset provided the basis for the investigation. The …
Published in International Journal of Genetic Modifications and Recombinations · Vol. 2, Issue 1, 2024 · pp. 1–15 Read article
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What Does Location of Abdominal Pain Say, Anatomically and Homoeopathically
Abstract: Background and justification for the study: Every symptom is an indication of bodily derangements which a patient feels when sick. The medical personal has to recognize these derangements only by symptomatic study of the disease without making any hypothetical theories. Therefore, examining symptoms is the sole correct method for determining the presentation of a disease. In Homoeopathy, a complete symptom is that which covers location, sensation, modalities and concomitant symptoms. …
Published in Research & Reviews : A Journal of Unani, Siddha and Homeopathy · Vol. 11, Issue 1, 2024 · pp. 14–19 Read article
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A Trends in Dietary Supplement Related to Exercise Nutrition
Abstract: A product made to address physiological or nutritional demands that might occur during sports activity is called a dietary supplement. It could offer a convenient method for fulfilling specific nutritional needs during exercise, or it could be utilized to prevent or address common nutritional deficiencies experienced by athletes. It is crucial to include the supplement in a thorough plan for the best possible sports nutrition or clinical care of nutritional …
Published in International Journal of Nutritions · Vol. 1, Issue 2, 2024 · pp. 1–6 Read article
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Millet Bran: Unveiling Its Potential Health Benefits
Abstract: Millet bran, derived from various millet grains, has emerged as a potent nutritional source, rich in fiber, vitamins, minerals, antioxidants, and omega-3 and omega-6 fatty acids. Its rising popularity is driven by its gluten-free nature, nutrient density, and sustainability. This review aims to explore the potential health benefits of millet bran, focusing on its digestive health, blood sugar control, heart health, antioxidant properties, and fatty acid composition. The Millet brand …
Published in International Journal of Nutritions · Vol. 1, Issue 2, 2024 · pp. 11–19 Read article
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Harmonization For Medical Device Regulation In Asia: A Vital Need
Abstract: The Medical Device area is one of the most perplexing and testing business portions of the medical services industry with a close joint effort between science and design. Notwithstanding the way that Asia has 60% of the world populace giving enormous market potential, Asian medical care consumption comprises just 15% of the worldwide medical services consumption. The sped-up maturing populace and expanding pervasiveness of ongoing infection are the key drivers …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 15, Issue 1, 2024 · pp. 31–37 Read article