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1365 articles for “Target”
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Solutions to the Cold Start Problem in Recommender System: A survey
Abstract: Collaborative Filtering (CF) is one of the techniques of recommender system to recommend the items to user based on previously collected preferences of other users. The efficiency of recommendation is mainly depending on how much information about target user and target item available in the system. When this information are not available sufficiently then it creates problem in the system for the new user and new item, which is known …
Published in Journal of Software Engineering Tools & Technology Trends · Vol. 5, Issue 3, 2018 · pp. 14–21 Read article
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Secure Interconnection of LDAP and DNSSEC PKI’s within Internet
Abstract: AbstractAfter decades of enlargement, net became a necessary tool helpful for professionals and personal people providing an outsized vary of services like emailing, management of bank accounts, reservation of hotels, train time schedules, real time traffic info, net search etc. If not targeted at the start, system security became quickly a key challenge for professionals and robust security solutions emerged on the market, primarily for professionals. Net security is therefore …
Published in Recent Trends in Programming languages · Vol. 3, Issue 3, 2016 · pp. 13–17 Read article
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Resolving Travelling Salesman Problem Using Modified Clustering Technique
Abstract: AbstractTravelling Salesman Problem (TSP) is a quotidian stumbling block in the field of Computer Science and operation research designed to seek out the shortest pathway amid the given targets viz. cities where each target is considered only once. Many solutions to this setback like Ant Colony Optimization. Brute-Force approach, Genetic Algorithm, Fruit Fly Optimization etc. are available in literature. The main objective of these solutions is to minimize the time …
Published in Research & Reviews: Discrete Mathematical Structures · Vol. 6, Issue 1, 2019 · pp. 22–31 Read article
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Study and Develop of an Effective Interface to Upload Data into ERP System
Abstract: AbstractIn today’s fast growing world, day-to-day many applications are being introduced in the market. These new applications have several advanced features when comparing to previous versions. New releases have features like performance improvement, user interface improvement, advance data base technology, web interfaces etc. So the enterprises need to change themselves in this competitive business world for financial business growth and to gain customer satisfaction. So when an organization go for …
Published in Recent Trends in Parallel Computing · Vol. 5, Issue 3, 2018 · pp. 44–53 Read article
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Study Analysis of Geolocational Data with Statistics: A Review
Abstract: The biggest challenge while traveling is looking for a place to stay, and considering doing a complete, thorough analysis of real-world data. The objective of the present study is to refer, clean, fetch, analyze and run K Means clustering on geolocational data to suggest lodgings to the travelers and immigrants of a city; maximizing the likelihood of the distances between the target and the landmarks, given the observed delays, yields …
Published in Journal of Advanced Database Management & Systems · Vol. 9, Issue 3, 2022 · pp. 25–30 Read article
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Canopy Design and Fabrication for Reducing Noise Level Generated at Work Place without Affecting Equipment/Machine Performance
Abstract: Abstract Laws governing the safety and health of employed people exist in most countries of the world, the purpose being to create a suitable working environment and eliminate unsafe practices and processes. Work areas should be designed and laid out so that they are satisfactory both, from the environmental and safety points of view. In this connection, safety also implies that noise is kept at a level, which is not …
Published in Journal of Refrigeration, Air conditioning, Heating and ventilation · Vol. 3, Issue 3, 2016 · pp. 24–29 Read article
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A Case Study on Heat Exchange Network Synthesis
Abstract: The requirement of energy in any processing industry is not only a need but it is indeed a most wanted utility. In a typical processing or manufacturing industry the most common utility are steam and cooling water. However, the cost of these utility are no longer cheap, in fact they are expensive. Therefore, saving these utility or minimizing the usage of these utilities is one of the most needed practice …
Published in Emerging Trends in Chemical Engineering · Vol. 4, Issue 1, 2017 · pp. 1–6 Read article
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Thermo-Mechanical Analysis of Aluminium and Mild Steel during Friction Drilling
Abstract: Friction drilling is a non-machining method of making holes in metal, in which the material is melted by adding high pressure and friction energy. Friction drilling uses very heat resistant cemented carbide, pointed but not sharp object. This device is pressed against a target material with both high rotational speed and high pressure. The process reshapes all thematerial so that no material is lost. The sleeve that is about three …
Published in Trends in Mechanical Engineering & Technology · Vol. 6, Issue 2, 2016 · pp. 18–24 Read article
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Colloidosomes: An Inherent Rigid Vesicle with Controlled Drug Distribution
Abstract: Colloidosomes are hollow capsules whose shell is composed of closely packed uniform colloidal particles. To date, colloidosomes have been fabricated using colloidal assembly at liquid-liquid interfaces. This system also solves the problem of insolubility, instability, rapid degradation and widely used in specialized areas like protein delivery, gene delivery, targeting to brain, tumour targeting, etc. In the series of vascular systems, colloidosome is the advanced tool in drug delivery. Colloidosomes have …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 7, Issue 3, 2016 · pp. 12–25 Read article
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Therapeutic Drug Monitoring (TDM): An Aspect of Clinical Pharmacology and Pharmacy Practice
Abstract: AbstractTherapeutic drug monitoring or TDM is the clinical pharmacology of measuring specific drugs at designated intervals to uphold a constant level of drug in a patient’s blood circulation, thereby optimizing individual dosage regimens. TDM becomes necessary only for the categories of drug with narrow therapeutic ranges, drugs with marked pharmacokinetic variability, medications for which target concentrations are difficult to monitor, and drugs known to cause therapeutic and adverse effects. On …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 5, Issue 3, 2015 · pp. 27–34 Read article
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Amplification and in silico Study of Plasmodium vivax and Plasmodium falciparum LDH Gene
Abstract: Several arsenal as well as quinolone drugs are available for treatment of malaria; still it remains a worldwide public health problem. Malarial parasite quickly develops resistance under selective drug pressure. Hence, we require an array of new drugs for malaria treatment. Lactate dehydrogenase (LDH) is an essential enzyme for Plasmodia as they lack functional Krebs cycle in some stages of their lifecycle and thereby prove to be good targets for …
Published in Research and Reviews: A Journal of Microbiology and Virology · Vol. 2, Issue 3, 2012 · pp. 1–5 Read article
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Effect of Hafnium on Nickel-Titanium based Thin Film Coating by DC/RF Magnetron Sputtering Technique
Abstract: Ni-Ti-Hf films as shape memory alloys were successfully prepared by magnetron sputtering technique using individual Ti, Ni and Hf targets. The hafnium content was varied from 6% to 30% and the required film composition was achieved by adjusting the power ratio to the targets. The as-deposited films were amorphous; a post deposition annealing was performed at 700 °C to crystallize the Ni-Ti-Hf films. Structural, compositional and phase-transformation studies were carried …
Published in Journal of Nanoscience, NanoEngineering & Applications · Vol. 2, Issue 3, 2012 · pp. 10–17 Read article
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Techniques for Characterization of Anticancer Drug Loaded Polymeric Nanoparticles: A Review
Abstract: Normal 0 false false false EN-US X-NONE X-NONE Polymeric nanoparticles have been used for targeted drug delivery against different diseases during last decades. Particularly in cancer, targeted polymeric nanoparticles can be used to deliver anticancer drugs to cancer cells with reduced cytotoxicity and greater efficacy. Various natural polymers like chitosan, albumin, gelatin and synthetic such as Polylactides (PLA), Poly (Lactide co-Glycolides) (PLGA) have been researched as carrier of anticancer drugs. …
Published in Journal of Nanoscience, NanoEngineering & Applications · Vol. 5, Issue 2, 2015 · pp. 32–43 Read article
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Homology Modeling of tRNA-dependent Amidotransferase from Malaria Parasite
Abstract: Normal 0 false false false EN-IN X-NONE X-NONE MicrosoftInternetExplorer4 Malaria is one of the most prevalent diseases in the world. The causative agent of malaria is a protozoan named Plasmodium. Many drugs have been invented against malaria parasite but increasing resistant against existing drugs necessitates the discovery of many new drugs. Plasmodium parasite is the member of apicomplexan group which harbor a plastid, apicoplast. The machinery of apicoplast protein synthesis …
Published in Research and Reviews : A Journal of Biotechnology · Vol. 2, Issue 1, 2012 · pp. 11–15 Read article
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Reduction of Heavy Metal by Biosorption
Abstract: Microorganisms can be used for treatment of metal and metalloid containing water streams in way to sequester the targeted species. The pollutants of concern include lead, chromium, mercury, uranium, selenium, zinc, arsenic, cadmium, gold, silver, copper and nickel. These toxic materials may be derived from mining operations, refining ores, sludge disposal, the processing of radioactive materials, metal plating, or the manufacture of electrical equipment, paints, alloys, batteries, pesticides or preservatives. …
Published in Research and Reviews : A Journal of Biotechnology · Vol. 2, Issue 3, 2012 · pp. 20–24 Read article
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Semi-quantitative Event Specific Detection of Bt Maize (Event MON 810) using Real-Time PCR with SYBR Green Ι Chemistry
Abstract: The objective is this work is to do semi-quantitative analysis for Bt maize (event MON 810) using conventional Polymerase Chain Reaction (PCR) and Real Time PCR (SYBR green chemistry) from the fresh maize samples chosen arbitrarily from various locations. The protocol for extraction of good quality genomic Deoxyribonucleic acid (DNA) was standardized without the use of Liquid nitrogen. The DNA used for further studies were obtained by using standardized protocol. …
Published in Research and Reviews : A Journal of Biotechnology · Vol. 2, Issue 3, 2012 · pp. 25–34 Read article
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CRISPR-Cas System: Next Generation Genome Editing Tool
Abstract: CRISPR-Cas system provides sequence specific adaptive immunity against phages and mobile genetic elements. Resistance is acquired following phage infection or plasmid uptake when short specific sequence is added into CRSIPR array. This complex guides cRNA to target complementary DNA fragments and target its degradation. CRISPR array is then transcribed and processed into cRNA which forms complex with cas protein. The ability of CRISPR-Cas system to induce site specific DNA breaks …
Published in Research and Reviews : A Journal of Biotechnology · Vol. 6, Issue 2, 2016 · pp. 10–16 Read article
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A Review about Scope of Traditional Medicinal Plants in a New Drug Discovery
Abstract: ‘AYUSH’ is the most important traditional system of medicine, which has been practised since thousands of long years by our ancestors. AYUSH has a very good healing power for so many problems by using both traditional and natural medicine. The new drug discovery is taking long time to produce its products and thus there is a reduction in number of new drug approvals due to different issues like legal problems …
Published in Research and Reviews : A Journal of Biotechnology · Vol. 7, Issue 2, 2017 · pp. 1–3 Read article
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Use of CRISPR/Cas9 in Delivery System with Nanotechnology Concept
Abstract: In this emerging era of science and technology development, the use of drug delivery concept has made possible to cure several health problems, but for certain genetic diseases like Sickle cell anemia, chronic diseases like cancers, Clustered Regularly Interspaced Short Palindromic Repeat (CRISPR)/CRISPR associated system (Cas) gene-editing system is here as a promising tool to cure them by doing certain gene manipulation in specific gene area causing the disease. However, …
Published in Journal of Nanoscience, NanoEngineering & Applications · Vol. 12, Issue 2, 2022 · pp. 16–23 Read article
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An in Silico Study of Selected Compounds from Garcinia spp. to Fight against Multidrug Resistant Bacteria
Abstract: AbstractBackground: Antibiotic resistant bacteria have emerged as a global threat. They have limited the number of available treatment options. New Delhi Metallo-beta-lactamase-1 (NDM-1) mediated drug resistance and efflux pump mediated drug resistance are among the major mechanisms associated with multidrug resistance.Objective: In our study, potential NDM-1 inhibitors as well as efflux pump inhibitors were identified through reverse chemogenomics from Garcinia spp. to deal with multidrug resistant bacteria. Method: Selected compounds …
Published in Research & Reviews: A Journal of Bioinformatics · Vol. 4, Issue 2, 2017 · pp. 1–4 Read article