Search
508 articles for “Anti – infective”
-
Seroprevalence and Immunity to Dengue Virus Among Women in Punjab: A Public Health Concern
Abstract: Dengue virus (DENV) infection continues to be a public health concern in Punjab, India, where women are at higher risk because of socioeconomic factors. This cross-sectional study sought to assess the DENV seroprevalence, their neutralizing antibody profiles, and the risk factors associated with DENV among a sample of 1,200 women (aged 18–50 years) in Punjab. Serum samples were processed by IgG/IgM ELISA, and plaque reduction neutralization tests (PRNT90) were done …
Published in Research and Reviews : A Journal of Immunology · Vol. 16, Issue 1, 2026 · pp. 6–10 Read article
-
Advanced Local Drug Delivery Approaches for Periodontitis: A Strategic Intervention
Abstract: Periodontal disease, one of the most prevalent oral diseases is caused by the gram negative bacterial infection of periodontal pocket identified by inflammation of subgingival plaque and degeneration of alveolar bones, teeth, dental cementum and periodontal ligaments. 80% of American adult and more than 50% of Indian community suffers from this chronic inflammatory disease depicting the severity of the disease. The objectives of the available therapies are to minimize the …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 9, Issue 1, 2018 · pp. 4–11 Read article
-
The Rising Burden of Heart Attacks: Causes, Trends, and Prevention Strategies
Abstract: Heart attacks, or myocardial infarctions, remain a leading cause of morbidity and mortality worldwide, with their incidence rising steadily across diverse populations. This review explores the increasing prevalence of heart attacks, emphasizing traditional risk factors, such as poor diet, physical inactivity, smoking, and medical conditions like hypertension, diabetes, and hyperlipidemia. It also highlights emerging risk factors, such as chronic infections, pollutants, substance abuse, and the lasting cardiovascular effects of COVID-19. …
Published in Research and Reviews : Journal of Surgery · Vol. 14, Issue 2, 2025 · pp. 1–11 Read article
-
Solitary Identification and Analysis of Considerate Nutritional Consumption and Identifying Malnutrition
Abstract: The food supply chain is in danger from various factors, including climate threats, such as heat waves, floods, droughts, and other extreme occurrences such as intensive livestock farming, demand for animal protein, practices for antimicrobial resistance and various other factors leading to serious food shortages and an increase in food prices. Malnutrition is a major issue, with an estimated 663 million individuals affected. Poor nutrition is a serious problem that …
Published in Journal of Artificial Intelligence Research & Advances · Vol. 10, Issue 2, 2023 · pp. 46–62 Read article
-
In Silico Drug Design for Mycobacterium tuberculosis and Development of Host–Pathogen Interaction Network and Molecular Docking Procedures
Abstract: Objective: A leading cause of illness is the contagious disease tuberculosis (TB), this infection with Mycobacterium tuberculosis complex (MTBC) particularly M. tuberculosis and M. africanum, is what causes tuberculosis. Diverse receptor proteins (mycobacterial proteins) with various 3D structures and functions were evaluated to access the multi-domain antimycobacterial action of ligands. The specific receptor proteins PDB ID: 3PTY, PDB ID: 4OW8, PDB ID: 5KWA, and PDB ID: 3ZXR, were opted for …
Published in International Journal of Molecular Biotechnological Research · Vol. 1, Issue 1, 2023 · pp. 1–19 Read article
-
Toxicological Profiling and Safety Assessment of NASAT 2.0: A Conceptual Framework for Adaptive Nanoparticle Therapy in Rabies
Abstract: Rabies, caused by the highly neurotropic Rabies lyssavirus, remains one of the most enigmatic and universally lethal infectious diseases known to modern medicine. Once clinical symptoms manifest following successful neuroinvasion, the fatality rate approaches absolute certainty (approximately 99.9%), a staggering statistic that has remained largely unchallenged despite massive, concurrent advances in modern virology, critical care medicine, and cellular immunology. Current late-stage therapeutic protocols, most notably the widely debated Milwaukee Protocol, …
Published in Research and Reviews: A Journal of Toxicology · Vol. 16, Issue 2, 2026 · pp. 1–19 Read article
-
A brief review on Influenza A virus (H 3 N 2 ) and its effects in human with precondition
Abstract: A primary cause of human influenza is the viral genus Influenzavirus A, of which H3N2 is a subtype. The virus has undergone various mutations, resulting in the emergence of different strains, affecting pigs, humans, and birds. H3N2 exchanges internal protein-coding genes with other influenza subtypes through reassortment. The H3N2 virus, which is a type of seasonal influenza A virus, is still circulating globally and is causing symptoms very similar to …
Published in Research and Reviews: A Journal of Microbiology and Virology · Vol. 13, Issue 1, 2023 · pp. 13–17 Read article
-
Changes of Super Oxide Dismutase Activity in Hemolymph, Hemocytes and Fat Body of Silkworm (Bombyx mori L.) Challenged by Micrococcus luteus and Escherichia coli
Abstract: The hemolymph, hemocytes and fat body of the silkworm, Bombyx mori L. were determined for superoxide dismutase (SOD) activity following bacteria Micrococcus luteus and Escherichia coli challenged using a photochemical assay system consisting of methionine, riboflavin, and p-nitro blue tetrazolium. The in vitro reduction of nitro blue tetrazolium by superoxide to formazan was measured spectrophotometrically in Bombyx Mori. Hemolymph, hemocytes and fat body were in response to various immune elicitors. …
Published in Research and Reviews : A Journal of Life Sciences · Vol. 2, Issue 2, 2012 · pp. 1–9 Read article
-
Monkeypox Virus (MPXV): Epidemiology, Pathogenesis, and Control Strategies: Exploring the Recent Resurgence of Monkeypox, Its Transmission Dynamics, Clinical Manifestations, and Public Health Responses
Abstract: Monkeypox virus (MPXV) has re-emerged as a significant public health concern, with increasing cases reported worldwide. This zoonotic virus, primarily endemic to Central and West Africa, has demonstrated the potential for human-to-human transmission, leading to outbreaks in non-endemic regions. Unlike smallpox, which was eradicated through mass vaccination, monkeypox continues to persist due to the lack of widespread immunity and effective antiviral treatments. The resurgence of MPXV in recent years, particularly …
Published in International Journal of Virus Studies · Vol. 2, Issue 1, 2025 · pp. 29–34 Read article
-
Defensive Mechanisms and Key Strategies with Its Specified Role in Mulberry Silkworm (Bombyx mori L.)
Abstract: Silkworms (Bombyx mori L.) possess a variety of defense mechanisms that play a vital role in protecting them against microbial infections and environmental stressors. These defense systems are primarily innate, relying on cellular and humoral responses. Cellular defenses include hemocytes which are responsible for processes like phagocytosis, encapsulation, and nodule formation. Humoral responses involve the production of antimicrobial peptides (AMP’s), such as cecropins, moricins, and lysozymes, which target invading pathogens. …
Published in International Journal of Insects · Vol. 1, Issue 2, 2024 · pp. 10–14 Read article
-
Urinary Tract Infection (Tadiya-e-Majra-e-Baul) in Unani System of Medicine
Abstract: In classical Unani system of medicine Tadiya-E-Majra-e-Baul. (Urinary Tract Infection) comes under the heading of Hirqatul-baul (burning micturition) which is caused by obstruction in Urinary Tract due to stone, Jisme Gharib (foreign body) Ghaliz Ghost (Badgosh), Hamal (Pregnancy), and Characterized by frequency of micturition, urgency of micturition, burning micturition and anuria . It is an Unani Medicine of Shora Qalmi, Rewand Chini and Kababchini. Having safe and good result in …
Published in Research & Reviews : A Journal of Unani, Siddha and Homeopathy · Vol. 7, Issue 2, 2020 · pp. 34–39 Read article
-
The Biogenesis, Transmission, Structural and Therapeutics on SARS-CoV-2 (COVID-19) Pandemic: Challenges and Global Perspective
Abstract: The present pandemic situation due to the appearance of COVID-19 has put the world in a miserable condition. About 2.5 million people have been infected with the strain of coronavirus SARS-CoV-2 (Severe Acute Respiratory Syndrome Coronavirus-2) globally. The foremost patient of COVID-19 infection was identified in China in the month of December 2019. Researchers are searching for an effective method to combat this pandemic virus. The investigations have been regulated …
Published in Research and Reviews : A Journal of Immunology · Vol. 11, Issue 1, 2021 · pp. 24–39 Read article
-
Elementary Mechanisms and Therapeutic Approaches for Epilepsy: A Neurodegenerative Impairment
Abstract: The main reason of the epilepsy is both genetic as well as acquired sources. Conventionally developed origins comprise thoughtful brain trauma and difficulties consequential from aforementioned infection. Mostly, the reason of epilepsy is not clear. Seizures may also transpire as a moment of additional health complications, like stroke, head injury, toxic assimilation, or metabolic delinquent. Epilepsy is treacherous when seizure befalls throughout pregnancy. Convinced anti-epileptic medicines upsurge the jeopardy of …
Published in Research and Reviews: A Journal of Neuroscience · Vol. 13, Issue 1, 2023 · pp. 41–46 Read article
-
In silico Bioprospection and Identification of Propitious Herbal Mitigators Against Highly Virulent Pathogenic Strains of Bacteria Like Vancomycin Resistant Enterococci
Abstract: Vancomycin resistance genes have been isolated from various strains of Enterococci, owing to the high rate of recombination and vast potential of disseminating resistant genes between Enterococcal strains. Various virulent factors contribute towards the dissemination of infections caused by such Multi-Drug Resistant (MDR) strains, ultimately leading to a devastating state of environmental contamination and cross infection. Minimizing the prevalence of these strains by multiple control efforts therefore is of paramount …
Published in Research & Reviews : Journal of Herbal Science · Vol. 4, Issue 1, 2015 · pp. 1–14 Read article
-
Comparative Study on the Antibacterial Activity of Pomegranate Rind Extract
Abstract: AbstractPomegranate (Punica granatum), is a fruit-bearing deciduous shrub grown easily all over the world. In India, these fruits are used in the Ayurveda for treatment of many diseases. The present study emphasized on the antibacterial activity of the peel extract (rind) of two Punica granatum varieties (Kesar and Ganesh) on Staphylococcus aureus, Escherichia coli, Proteus vulgaris, Bacillus sps. and Pseudomonas aeruginosa. Methanol extract was found to be effective in Kesar …
Published in Research & Reviews : Journal of Herbal Science · Vol. 2, Issue 1, 2013 · pp. 1–6 Read article
-
Plant-Derived Vaccines: A Sustainable Approach to Disease Control for Global Health
Abstract: Plant-based vaccines present a novel and environmentally responsible approach to vaccination, with significant potential for improving both human and animal health. These vaccines are safer and less expensive than traditional vaccine manufacturing methods because they use genetically modified plants to create antigens that elicit an immune response. Plant-based systems offer a potential remedy for traditional vaccines' high production costs and environmental impact, which are growing problems. Plant-derived vaccines have shown …
Published in Research and Reviews: A Journal of Microbiology and Virology · Vol. 15, Issue 1, 2025 · pp. 17–20 Read article
-
Pathogenesis and Treatment of Tuberculosis (T.B) Disease
Abstract: Tuberculosis (TB) is an infectious illness spread through the air that is caused by organisms from the Mycobacterium tuberculosis complex. M. tuberculosis is a lung infection in primary stage, but it can infect any area of the body. M. tuberculosis infection can progress from latent TB infection, in which the bacteria are isolated within granulomas, to infectious infection, in which the patient develops symptoms such as cough, fever, night sweats, …
Published in Research and Reviews : A Journal of Immunology · Vol. 11, Issue 3, 2021 · pp. 42–48 Read article
-
Role of Alkalinized Topical Heparin and Lignocaine Preparation in Burn Wound
Abstract: Burns can severely damage a patient's physical and mental health. We should consider pain, hospital stays, lost workdays, and financial strain while handling these patients. Burn patients need rapid specialist care to reduce morbidity and death. Heparin is anti-inflammatory, allergic, histaminic, serotonin-blocking, and proteolytic enzyme-blocking. Topical forms have been used to prevent burn extension, limit skin tissue loss, promote quicker healing with fewer contractures, relieve pain, reduce tissue oedema and …
Published in Trends in Drug Delivery · Vol. 10, Issue 2, 2023 · pp. 16–19 Read article
-
Clinical experience with Ayurvedic Treatment in Case of Rheumatoid Arthritis – Ayurvedic review and Case study
Abstract: Rheumatoid arthritis is the most found inflammatory auto immune disease with unknown etiology. Many clinical features and treatment strategies of RA are associated with multiple joint diseases. The clinical phenotype of Rhematoid arthritis is a symmetrical, deformed polyarthritis of small and large joints, which is often associated with features of the disease. The treatment typically involves ongoing management with periods of worsening symptoms followed by periods of improvement. Features of …
Published in Research and Reviews : A Journal of Ayurvedic Science, Yoga and Naturopathy · Vol. 11, Issue 2, 2024 · pp. 1–8 Read article
-
Early Life Nutrition as a Determinant of Long-Term Vaccine Immunogenicity in Livestock: Mechanisms, Practical Strategies, and Species-Specific Considerations
Abstract: Early life represents a critical period for immune system development in livestock, during which nutritional exposures can exert long lasting effects on vaccine immunogenicity. Although vaccination is a cornerstone of infectious disease control in food producing animals, marked variability in vaccine induced immune responses is frequently observed under commercial conditions. Growing evidence suggests that this variability is partly driven by differences in early nutritional status, which can influence immune maturation, …
Published in International Journal of Vaccines · Vol. 3, Issue 1, 2026 · pp. 15–26 Read article