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Trends in Drug Delivery

Role of Alkalinized Topical Heparin and Lignocaine Preparation in Burn Wound

  1. Ravi Kumar Chittoria
  2. Dr Killi Madhu Babu
  3. Barath Kumar Singh. P

Abstract

Burns can severely damage a patient's physical and mental health. We should consider pain, hospital stays, lost workdays, and financial strain while handling these patients. Burn patients need rapid specialist care to reduce morbidity and death. Heparin is anti-inflammatory, allergic, histaminic, serotonin-blocking, and proteolytic enzyme-blocking. Topical forms have been used to prevent burn extension, limit skin tissue loss, promote quicker healing with fewer contractures, relieve pain, reduce tissue oedema and weeping, prevent infection, and promote revascularization, granulation, and epithelialization of deeply burned tissue. Topical lignocaine application in gel formulation has been tried in raw areas and post skin grafting raw areas. Positive results have been obtained demonstrating significant pain relief with use of topical local anesthetic. In addition to pain, it is shown to reduce edema and post burn ischemia. We here discuss mixture of topical heparin and local anesthetic in burn care in this case report.

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