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354 articles for “therapeutics methods”
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Ilaj bil-Ma’ (Hydrotherapy) as a Regimenal Modality in Pain Management: Conceptual Foundations in Unani Medicine and Modern Correlation
Abstract: Waja‘ (pain) is one of the most common clinical complaints encountered worldwide and remains a leading cause of disability, impaired functional capacity, and diminished quality of life. In the Unani system of medicine, pain is not considered merely a symptom but a significant manifestation of disturbed physiological balance. Classical Unani scholars describe pain as arising from derangement in Mizāj (temperament), imbalance of Akhlāṭ (humours), Sudad (obstruction within bodily channels), Waram …
Published in Research & Reviews : A Journal of Unani, Siddha and Homeopathy · Vol. 13, Issue 2, 2026 · pp. 12–19 Read article
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Molecular Docking and Interaction of Anthocyanin Derivatives in Regulating Hippo-taz Pathway for Renal Injuries
Abstract: Introduction: The Hippo pathway plays a pivotal role in renal disease, with Yes-associated protein (YAP) exhibiting promise for combined treatments. The crucial evaluation of YAP-targeted drug safety and efficacy through preclinical studies is imperative. Additionally, α-SMA and SMAD3 emerge as potential therapeutic targets in renal fibrosis, driving ongoing research toward innovative interventions. Materials and Methods: In the systematic identification of therapeutic secondary metabolites, Anthocyanin derivatives were methodically retrieved from the …
Published in International Journal of Genetic Modifications and Recombinations · Vol. 2, Issue 1, 2024 · pp. 23–38 Read article
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The use of Genetics and Proteomics in the Finding of Therapeutic Targets
Abstract: Gene medicine is overcoming long-standing health issues that have confounded humanity. To fully comprehend and apply gene medicine, it is vital to grasp how it works at the molecular level. Currently, various technologies may be utilized to find pharmacological targets; the two most prominent are genomic and proteomic methods. In this paper, we go over how to use genomic and proteomic approaches to find pharmacological targets in depth. These materials …
Published in Research and Reviews : Journal of Computational Biology · Vol. 11, Issue 1, 2022 · pp. 9–12 Read article
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DMARDs, Biologic Agents and Novel Experimental Strategies in The Treatment of Rheumatoid Arthritis
Abstract: An inflammatory and autoimmune disease, rheumatoid arthritis (RA) causes severe pain and inflammation in affected areas of the body. According to the report, there is no known cure for RA. Therefore, reducing discomfort and halting future harm must be the goals of present therapy. For the purpose of prevention and to reduce disease activity in RA patients, significant success has been achieved with the continued development of disease-modifying antirheumatic drugs …
Published in Emerging Trends in Personalized Medicines · Vol. 1, Issue 1, 2024 · pp. 14–24 Read article
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A Research Study on Cognitive Health Benefits of Nicotine to the Human Body
Abstract: Background: Nicotine has been primarily known for its addictive properties and associated health risks, particularly in tobacco products. However, recent research has highlighted nicotine’s potential cognitive health benefits, especially in neurodegenerative diseases like Alzheimer’s and Parkinson’s. This study investigates smoking prevalence across mental health conditions, and cognitive impairments in various psychiatric disorders, and explores the possible cognitive health benefits of nicotine. Methods: Data on age and gender distribution, smoking prevalence, …
Published in Research & Reviews: A Journal of Drug Design & Discovery · Vol. 12, Issue 1, 2025 · pp. 16–23 Read article
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Physiotherapy’s Impact on an Athlete’s Physical and Mental Well-being: A Review
Abstract: Physiotherapists are essential in helping athletes with physical and psychological issues connected to their activity. Effective treatment and the formulation of athletes' expectations regarding the restoration of health issues require a solid interaction between the physiotherapist and the athlete. Thus, when designing a rehabilitation program, it is imperative to take the expectations of the athletes with the specific problem into consideration. Since the dawn of civilization, physiotherapy methods have been …
Published in International Journal of Orthopedic Nursing and Practices · Vol. 2, Issue 1, 2024 · pp. 22–28 Read article
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A Critical Review of Gandhaka & Its Shodhan Research Work with Special Emphasis on the 1st Method Following Rasatarangini
Abstract: Background: Ayurveda is an ancient healthcare system that influences many modern treatments. One of its key branches, Rasa Shastra, studies the health benefits of strong minerals and metals like mercury, sulphur, mica, and black bitumen. Among these, sulphur is critical for detoxification, blood purification, and digestion, being the third most common element in the human body after calcium and phosphorus. Before sulphur is used in Ayurvedic medicine, it must be …
Published in Research and Reviews : A Journal of Ayurvedic Science, Yoga and Naturopathy · Vol. 12, Issue 3, 2025 · pp. 1–11 Read article
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A Comprehensive Analysis of Alzheimer’s Disease
Abstract: Alzheimer's disease, the most prevalent form of dementia, is a progressive neurological disorder characterized by cognitive decline, particularly in memory function. The condition manifests in two primary forms: familial Alzheimer’s disease, affecting individuals under the age of 65 years, and sporadic Alzheimer’s disease, which constitutes the majority of cases and primarily afflicts adults aged 65 years and older. The prevalence of Alzheimer’s disease is influenced by various factors, such as …
Published in Research and Reviews: A Journal of Toxicology · Vol. 13, Issue 2, 2023 · pp. 26–32 Read article
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Homeopathic Posology: Principles and Practice
Abstract: The cornerstone of homeopathy lies in the principle of individualized therapy, and this concept is equally significant in determining the posology of homeopathic medicines. Unlike conventional medicine, where dosage is often standardized, homeopathic posology is carefully adapted to the specific condition and overall state of the patient. The primary source of guidance for homeopathic prescribing is Hahnemann’s Organon of Medicine, a seminal work published in six successive editions, each reflecting …
Published in Journal of AYUSH: Ayurveda, Yoga, Unani, Siddha and Homeopathy · Vol. 14, Issue 3, 2025 · pp. 52–58 Read article
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Extrapolations of Periwinkle Secondary Metabolites as Multitarget Inhibitor of Breast Cancer Proteins
Abstract: Objective: Breast cancer is considered one of the most common and dangerous forms of cancer. It is a significant public health issue on a global scale. The study estimates that 10.0 million people will die from cancer this year, and 19.3 million people will develop the disease overall (BC). In this computation approach, nowadays emphasizes new drug discovery, the target protein epidermal growth factor receptor (EGFR) (5UGB), estrogen receptor (ER) …
Published in International Journal of Biochemistry and Biomolecule Research · Vol. 1, Issue 1, 2023 · pp. 36–49 Read article
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Dieto-Therapy (Ilaj-bil-ghiza) in Unani System of Medicine: From Concept to Practice in the Management of Non-communicable Diseases
Abstract: Unani physicians paid a great attention towards ilaj-bil-ghiza (dieto-therapy). They used to treat a number of ailments by alteration in quantity and/or quality of Ghiza. Their knowledge about its nutritive as well as its pharmacological activity was vast as evident from the Unani classical literature. The classification of Unani drugs is based on medicinal and nutritive values. The former is known as dawa and later is ghiza. Further, a combination …
Published in Journal of AYUSH: Ayurveda, Yoga, Unani, Siddha and Homeopathy · Vol. 4, Issue 2, 2015 · pp. 54–59 Read article
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Extrapolations of Periwinkle Secondary Metabolites as Multitarget Inhibitor of Breast Cancer Proteins
Abstract: Objective: Breast cancer is considered as one of the most common and dangerous forms of cancer. It is a significant public health issue on a global scale. The study estimates that 10.0 million people will die from cancer this year, and 19.3 million people will develop the disease overall (BC). In this computation approach nowadays emphasises for new drug discovery, the target protein EGFR (5UGB), ER (2QGT), and PI3KA (4OYS) …
Published in Research and Reviews: Journal of Oncology and Hematology · Vol. 11, Issue 3, 2022 · pp. 22–36 Read article
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Modulation of Receptor Proteins: A Recent Paradigm in Drug Discovery and Target
Abstract: The main aim in drug discovery is to design different ligands those work on specific drug targets. However, various effective drugs work through the modulation of many proteins than single target. Advancement in system biology are establishing a phenotypic strength and a network structure, which suggests that, the excellent selective compounds may be performed less than desired clinical efficacy in comparison to multi-target drugs. In this new appreciation of the …
Published in Research & Reviews: A Journal of Drug Design & Discovery · Vol. 5, Issue 1, 2018 · pp. 14–24 Read article
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Integration of Biomarkers in III and IV CKD Patients for Evaluation of Their Predictive Value for CVD in CKD Patients
Abstract: Background: Chronic kidney disease (CKD) is presently characterized by the presence of proteinuria and/or a diagnosis of renal impairment. The worldwide significance of CKD is underscored by the fact that its prevalence and incidence have doubled over the past three decades. This paper provides an overview of the existing evidence regarding biomarkers in individuals with CVD or CKD, with a particular focus on the emerging biomarkers (i.e., eGFR, sALB, UACR, …
Published in Research and Reviews: A Journal of Medicine · Vol. 15, Issue 3, 2025 · pp. 1–12 Read article
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An Overview of Rheumatoid Arthritis: Enhancing Current Treatment Strategies Using Nanomaterials
Abstract: Background and Aim: Rheumatoid arthritis (RA) is a persistent and progressive autoimmune disease commonly affecting many people worldwide that severely attacks joints, leading to inflammation, cartilage destruction, and bone erosion. Exhaustive research on RA over the years has significantly contributed to a better understanding of the disease's causes, mechanism, progression, and treatment. Several therapies are available for its management, including anti-inflammatory and disease-modifying antirheumatic drugs. This present review aims at …
Published in Nano Trends – A Journal of Nano Technology & Its Applications · Vol. 25, Issue 1, 2023 · pp. 50–78 Read article
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Rapid Biosynthesis of Silver Nanoparticles of Flower-like Morphology from the Root Extract of Saussurea lappa
Abstract: With the emergence of nanomedicine, nanobiotechnology, and nanopharmacotherapeutics, there has been a rising demand of nanomaterials. Silver nanoparticles (AgNPs) finds immense applications for drug delivery, biomedical sciences, catalysis, etc. Numerous industries are at present synthesizing therapeutic AgNPs to meet the global demand. By using chemical methods, which are very cost-effective to produce these materials, are quite hazardous, environment polluting, produce harmful byproducts, and have several other alarming aspects. The extract …
Published in Research & Reviews: A Journal of Pharmacognosy · Vol. 5, Issue 1, 2018 · pp. 20–24 Read article
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In-silico screening of phytochemicals for identification of an alternative therapy for thyroid cancer
Abstract: Thyroid cancer remains a significant health concern globally, necessitating the exploration of novel therapeutic alternatives to improve treatment outcomes. This study targets COT kinase (Cancer Osaka Thyroid Kinase), a protein implicated in the progression of thyroid cancer, using molecular docking methods with various phytochemicals to identify potential therapeutic compounds. PyRx and Discovery Studio were employed to evaluate the interactions and binding affinities of a diverse set of natural compounds with …
Published in International Journal of Toxins and Toxics · Vol. 2, Issue 2, 2025 · pp. 31–55 Read article
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Preparation of Tamra Bhasma (Copper) by Niragni (Solar Energy) Method
Abstract: The metal Tamra (Copper)is mentioned in Ayurveda with a wide range of therapeutic utilities. Considering the significance of Tamra in therapeutics, many studies have been carried out at different centers of India. The main purpose of this study was to discover an ecofriendly, cost-effective and easy method of preparation of Tamra Bhasma. Method adapted was, purified Tamra Patra (Copper plate) mixed with Kajjali (a mixture of purified Parada and Gandhaka) …
Published in Research & Reviews: A Journal of Drug Formulation, Development and Production · Vol. 6, Issue 3, 2019 · pp. 49–53 Read article
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Assessment of Finerenone Safety and Efficacy in Individuals with Type 2 Diabetes and Chronic Kidney Disease
Abstract: Background: In this work, we provide strong evidence for the safety and efficacy of finerenone in people with type 2 diabetes and chronic kidney disease. Our goal is to improve patients' quality of life and general well-being through our research. Aim: Finerenone exhibited a significant decrease in the likelihood of renal and cardiovascular (CV) events in individuals with both type 2 diabetes and chronic kidney disease. This exploratory subgroup analysis …
Published in International Journal of Antibiotics · Vol. 1, Issue 2, 2024 · pp. 06–09 Read article
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AQUASOMES: A Vesicular, Self-assembled Ceramic Nanoparticulate Drug Carrier
Abstract: Nano-biopharmaceutics involves delivery of biopharmaceutical product through different biomaterials like multi-functional nanoparticles, quantum dots, aquasomes, super-paramagnetic iron oxide crystals, and liposomes dendrimers. Aquasomes are considered as one of the most recently developed delivery systems for bioactive molecules like peptides, proteins, hormones, antigens and genes to specific sites. Aquasomes have a spherical shape and a particle size of 60–300 nm. These are three layered self-assembled nano-particulate carrier system. This three-layered structure …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 12, Issue 3, 2025 · pp. 1–14 Read article