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76 articles for “polymeric nanoparticles”
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Reinventing Drug Delivery Through Cutting-Edge Nanotechnology
Abstract: Nanotechnology has emerged as a revolutionary platform in the field of drug delivery, offering novel strategies for the precise, efficient, and controlled delivery of therapeutic agents. The integration of nanocarriers, such as liposomes, polymeric nanoparticles, dendrimers, micelles, and inorganic nanoparticles, has significantly enhanced drug solubility, stability, bioavailability, and targeted delivery to specific tissues or cells. Targeted drug delivery systems based on nanotechnology minimize off-target effects, reduce systemic toxicity, and improve …
Published in Trends in Drug Delivery · Vol. 12, Issue 3, 2025 · pp. 44–61 Read article
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Next-Generation mRNA Therapeutics: Self-Amplifying, Thermostable and Personalized mRNA Vaccines in the Era of Precision Medicine
Abstract: Messenger RNA (mRNA) technology has brought a major change in modern medicine, especially after its successful use in COVID-19 vaccines. However, early mRNA vaccines faced several problems such as low stability, strict cold storage requirements, and lack of personalized treatment. To overcome these challenges, next-generation mRNA technologies have been developed, including self-amplifying mRNA (saRNA), thermostable mRNA vaccines, and personalized mRNA vaccines. This article discusses the development of mRNA therapeutics, the …
Published in International Journal of Vaccines · Vol. 2, Issue 2, 2025 · pp. 38–54 Read article
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Comprehensive Evaluation of Quercetin from Bauhinia purpurea for Its Anti-Acne and Anti-Inflammatory Potential, Including Advances in Quercetin-Loaded Nanogel Formulation
Abstract: Acne vulgaris is among the most prevalent chronic inflammatory dermatoses in clinical dermatology, afflicting a substantial proportion of the global adolescent and adult population. Conventional pharmacotherapies — including topical retinoids, benzoyl peroxide, and systemic antibiotics — remain the therapeutic mainstay; however, their long-term utility is progressively undermined by adverse cutaneous reactions, systemic toxicity, and the rising prevalence of antibiotic-resistant Cutibacterium acnes strains. These limitations have intensified scientific interest in plant-derived …
Published in Research & Reviews: A Journal of Drug Formulation, Development and Production · Vol. 13, Issue 2, 2026 Read article
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Enhancing the Bioavailability of Polyphenols: A Comprehensive Review
Abstract: The polyphenolic compounds are abundantly found in different plant parts including fruits, leaves, stem and seeds, and are known for possessing a wide range of biological activities. These include antioxidant, antimicrobial, anti-inflammatory, anticancer, antidiabetic, cardioprotective, and neuroprotective effects. Their functional relation with their structure highlights the significant therapeutic potential. As a result, the polyphenols are being further being exploited for applications in functional foods, pharmaceuticals, and targeted drug delivery. Despite …
Published in Research & Reviews : Journal of Food Science & Technology · Vol. 15, Issue 2, 2026 · pp. 37–51 Read article
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Interfacial and Tribo-Mechanical Performance of a TiO₂–Castor Oil Polymeric Nanofluid During Sustainable Machining of AISI 316L Stainless Steel Under MQL Conditions
Abstract: This research examines the tribo-mechanical performance and interfacial film characteristics of a TiO₂-reinforced castor-oil polymeric nanofluid during the turning of AISI 316L stainless steel under minimum-quantity lubrication (MQL). A Taguchi L9 orthogonal array was utilized to assess the synergistic effects of cutting speed, depth of cut, and coolant composition on surface integrity, while machining experiments were performed under dry, conventional, and TiO₂-nanofluid lubrication techniques. ANOVA and multiple-regression modeling were used …
Published in Journal of Polymer & Composites · Vol. 14, Issue 1, 2026 · pp. 901–914 Read article
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Facile Synthesis and Characterization of Cd²⁺ Doped NiAl₂O₄ Nanoparticles for Advanced Polymer Composite Integration
Abstract: Ni1-xCdxAl2O4, where 0 ≤ x ≤ 0.5, was successfully synthesized using the chemical co-precipitation technique, a scalable and cost-effective route suitable for composite material applications. X-ray diffraction (XRD) analysis revealed a crystalline cubic spinel structure for the resulting nanoparticles, with determined crystallite sizes ranging from 36 to 12 nm for NiAl2O4 and Cd-doped NiAl2O4. The respective band gaps for the materials were found to be 3.51 and 4.18 eV. Infrared …
Published in Journal of Polymer & Composites · Vol. 13, Issue 5, 2025 · pp. 59–72 Read article
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Exploration of Copper Oxide PVA/PEG Paraffin Polymer Composites for Enhanced Thermal Performance of Nano-Enhanced Phase Change Materials and Their Environmental Impact
Abstract: This study investigates the synthesis, characterization, and application of copper oxide (CuO) nanoparticles integrated into polymer-based paraffin wax composites for advanced thermal management applications. CuO nanoparticles were synthesized using a wet chemical approach and characterized through X-ray diffraction (XRD), scanning electron microscopy (SEM), transmission electron microscopy (TEM), and dynamic light scattering (DLS), confirming their crystalline structure, morphology, and nanoscale size distribution. The synthesized nanoparticles were incorporated into polymer-supported phase change …
Published in Journal of Polymer & Composites · Vol. 14, Issue 1, 2026 · pp. 156–173 Read article
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Role of Polymeric Composites in Controlled Drug Release Systems
Abstract: In the realm of controlled drug release systems, polymeric composites have attracted a lot of interest as they possess several diverse characteristics that enable exact control of the drug delivery rate. This lowers adverse effects and increases the efficacy of treatment. Usually composed of biocompatible polymers combined with functional fillers like nanoparticles, ceramics, or hydrogels, these composites help to get the desired drug release patterns. Stable, biodegradable, and bioactive materials …
Published in Journal of Polymer & Composites · Vol. 13, Issue 4, 2025 · pp. 453–465 Read article
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Nano‑Enabled CT for Cancer Imaging: From Molecular Targeting to Image‑Guided Therapy
Abstract: Nano‑enabled computed tomography (CT) exploits high‑atomic‑number (high‑Z) nanomaterials engineered with targeting ligands and therapeutic payloads to enhance contrast, enable molecular imaging, and support image‑guided interventions in oncology. Tumor‑specific nanoprobes such as RGD‑modified gold nanorods, polymer‑coated bismuth nanoparticles, and peptide, antibody, or aptamer‑functionalized platforms can intensify tumor conspicuity, allow early lesion detection and staging, and provide real‑time treatment monitoring. Integration of CT visibility with photothermal, photodynamic, chemo‑, radio‑, and immunotherapeutic functions …
Published in Nano Trends – A Journal of Nano Technology & Its Applications · Vol. 28, Issue 1, 2025 · pp. 40–49 Read article
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Melanoma Skin Cancer Detection Using Deep Learning
Abstract: Cancer as one of the major diseases rank in the World is still very challenging to diagnose and treat hence need for the technological advancements. Chemotherapy, radiation, as well as surgery therapies have several drawbacks including non-selective action, damage to healthy tissues, and multi-drug resistance. Smart nano-theranostics, an advanced integration of nanotechnology with diagnostic and therapeutic modalities, offers a next-generation approach for precision oncology. Thus, the development of multifunctional nanoparticles …
Published in Research and Reviews: Journal of Oncology and Hematology · Vol. 14, Issue 2, 2025 Read article
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Microsphere and Nanoparticle Drug Delivery Systems: Role of Polymers in Pharmacology
Abstract: Microsphere and nanoscale drug delivery methods have changed the field of pharmacology by making treatment agents more bioavailable, more targeted, and easier to manage. These delivery systems, which are mostly made up of polymers, look like a good way to get around the problems that traditional drug formulations have, like not dissolving well, clearing quickly, and spreading in different places. Plastics are very important in the creation of these improved …
Published in Journal of Polymer & Composites · Vol. 13, Issue 4, 2025 · pp. 420–432 Read article
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Water Chestnut Stem-Derived Biochar Supported AgNPs/AC-CTS-PVA Composite Gel for Wastewater Treatment and Potent Antibacterial Performance
Abstract: In the present study, green and efficient Ag-NPs functionalized activated carbon/chitosan-polyvinyl alcohol (AgNPs/AC-CTS-PVA) composite gel was successfully synthesized using water chestnut stem-derived biochar for wastewater treatment and antibacterial applications. The composite was characterized by FTIR, XRD, SEM-EDX, and TGA analyses, confirming the successful incorporation of crystalline Ag nanoparticles within the polymeric matrix and improved thermal stability. The material was tested regarding the removal of the dye of methylene blue (MB) …
Published in Journal of Polymer & Composites · Vol. 14, Issue 2, 2026 · pp. 1129–1144 Read article
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Polymeric Nanocomposite Aided Bioaugmentation for Marine Oil Spills – A Review
Abstract: Bioaugmentation is a promising, cost-effective bioremediation technique that enhances the degradation of marine pollutants by introducing hydrocarbon-degrading microorganisms. This review explores recent advancements in the use of bioaugmentation for petroleum biodegradation in marine environments, emphasizing the integration of microbial systems with polymeric and composite materials. Innovative methods, such as the immobilization of microbial cells within biodegradable polymeric matrices (e.g., alginate, chitosan, polyvinyl alcohol), have significantly improved microbial viability, metabolic efficiency, …
Published in Journal of Polymer & Composites · Vol. 14, Issue 3, 2026 · pp. 1049–1061 Read article
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Polymer Chemistry and Composite Materials in Biomedical Applications
Abstract: The integration of polymer chemistry and composite materials has revolutionized biomedical applications. Recent advancements in polymer synthesis, functionalization, and nanotechnology have further expanded their applications, leading to significant improvements in biocompatibility, biodegradability, and mechanical performance. These polymeric carriers protect bioactive compounds from enzymatic degradation, enable controlled drug release, and improve therapeutic efficacy. The integration of polymer chemistry with nanotechnology has enabled the development of highly efficient, targeted therapeutic systems that …
Published in Journal of Polymer & Composites · Vol. 13, Issue 4, 2025 · pp. 413–419 Read article
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Nano-Chemical Revolution in Vaccinology: A Study
Abstract: The development of traditional vaccines, reliant on attenuated pathogens or purified proteins, has historically been limited by slow development timelines, poor stability, and low immunogenicity requiring potent, often non-specific, adjuvants. This synthesis argues that the convergence of nano-material science and meticulous chemical engineering represents the next major paradigm shift in preventative medicine. Nano-materials, particularly Lipid Nanoparticles (LNPs) and various polymeric or inorganic scaffolds, have transitioned from theoretical constructs to essential …
Published in Research and Reviews : A Journal of Immunology · Vol. 16, Issue 1, 2026 Read article
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Effect of Nano Metal Oxide Loading Rates on Polymer-Nano Metal Oxide Nanocomposites
Abstract: Many industries, such as those in the fields of medicine, textiles, cosmetics, agriculture, optics, food packaging, optoelectronics, semiconductors, aerospace, building materials, and catalysis, utilise nanoparticles and nanocomposites in a variety of applications. A unique class of materials, polymeric nanocomposites outperform their microparticle counterparts by fusing organic polymers with inorganic nanoparticles. Consequently, they ought to advance the field of engineering applications. The presence of inorganic nanoparticles can significantly alter the properties …
Published in Journal of Nanoscience, NanoEngineering & Applications · Vol. 14, Issue 1, 2024 · pp. 1–12 Read article
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Polymeric Materials in Drug Delivery: Applications in Topical Formulations
Abstract: Polymeric materials play a crucial role in modern drug delivery systems, particularly in topical formulations. These materials enhance drug stability, control release rates, and improve bioavailability, making them essential components in pharmaceutical advancements. Polymers such as chitosan, hydrogels, and emulsifying agents are widely utilized in immediate-release topical formulations, where they contribute to improving therapeutic efficacy by ensuring uniform drug distribution, increased solubility, and enhanced skin penetration. The integration of polymer-based …
Published in Journal of Polymer & Composites · Vol. 13, Issue 5, 2025 · pp. 34–41 Read article
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RNA- Based Drug Delivery, Current Advances, Pharmaceutical Applications, and Future Perspectives
Abstract: RNA-based therapeutics have emerged as a transformative approach in modern medicine due to their ability to regulate gene expression with high specificity and precision. Advances in molecular biology, RNA chemistry, and nanotechnology have accelerated the development of diverse RNA modalities, including messenger RNA (mRNA), small interfering RNA (siRNA), microRNA (miRNA), antisense oligonucleotides (ASOs), and RNA aptamers. These therapeutics offer promising strategies for the treatment of cancer, genetic disorders, infectious diseases, …
Published in Research & Reviews: A Journal of Drug Design & Discovery · Vol. 13, Issue 2, 2026 Read article
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Performance and Emission Profiles Enhancement of CI Engine with Aluminium Oxide-Reinforced Polymeric Composite in Biodiesel Blends
Abstract: The integration of aluminium oxide (Al₂O₃) nanoparticles into B10 biodiesel blends offers a promising approach to improving engine performance and reducing harmful emissions. This study evaluates the effect of Al₂O₃ additives on Brake Thermal Efficiency (BTE), Brake Specific Fuel Consumption (BSFC), and exhaust emissions in a compression ignition engine. Experiments were conducted using calibrated instruments, and uncertainties were considered with a coverage factor of 1.66, yielding an overall error margin …
Published in Journal of Polymer & Composites · Vol. 14, Issue 1, 2026 · pp. 775–788 Read article
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Biodegradable and Natural Fiber-Reinforced Polymer Composites for Antimicrobial Coatings in Biomedical Applications
Abstract: Since they make medical equipment more biocompatible and practical, biomedical polymers are quite crucial for the advancement of medical technologies. One of the most exciting applications for biomedical polymers is their possible use as protective drug coatings for devices. These coatings aim to limit bacterial binding and biofilm growth, two key causes of illnesses acquired after implantation. Scientists are searching for fresh approaches to combat microorganisms as the issue of …
Published in Journal of Polymer & Composites · Vol. 13, Issue 6, 2025 · pp. 392–405 Read article