Search
171 articles for “neurodegeneration Beta-amyloid peptide”
Nothing matched all of your words, so these match any of them.
-
Free Fatty Acids Modulate the Specific Activity and Expression of Alpha and Beta Subunits of Sodium Potassium ATPase of Cultured Rat Cortical Astrocytes.
Abstract: The fatty acid composition of the membrane plays an important role in the functioning of the membrane-bound enzyme Na+K+ATPase. The aim of this study was to determine the effects of the free fatty acids at various levels of unsaturation, namely, stearic acid, linoleic acid, arachidonic acid and docosahexaenoic acid, on the alpha and beta subunits of sodium potassium ATPase present on the primary cultures of rat astrocyte membrane. Membrane was …
Published in Research and Reviews: A Journal of Neuroscience · Vol. 2, Issue 1, 2012 · pp. 20–28 Read article
-
Case Control Analysis on Neurodegeneration Disorders and Autism in Familial Context
Abstract: Neurodegenerative disorders such as Parkinson's and Alzheimer's co-occur with autism spectrum disorder (ASD), indicating shared genetic factors. Oxidative stress and inflammation play roles, with an elevated risk of Parkinson's and dementia in individuals with autism spectrum disorder. Antioxidant levels are linked to language and behaviour in autistic children. In the present study, a systematic review and meta-analysis was done following the PRISMA guidelines, reviewing English articles (2002- 2022) on familial …
Published in Research and Reviews: A Journal of Neuroscience · Vol. 13, Issue 2, 2023 · pp. 31–39 Read article
-
Neurodegeneration and Cognitive Decline: Causes, Consequences, and Treatment Approaches
Abstract: Neurodegenerative diseases gradually destroy nerve cells, often leading to fatal outcomes. The phrase includes a wide range of clinical problems, such as a variety of Neurological conditions include movement disorders, like Parkinson’s disease (PD) and progressive cognitive impairments, with Alzheimer’s disease (AD) being the most common among them. A loss of neurones and synaptic connections, typically in later life, is a prevalent feature of Usually, the onset and development of …
Published in International Journal of Cell Biology and Cellular Functions · Vol. 3, Issue 1, 2025 · pp. 47–59 Read article
-
Kisunla (Donanemab): A Novel Breakthrough Illuminating a Path to Better Alzheimer’s Outcomes
Abstract: Background: Alzheimer’s disease (AD) is a progressive neurodegenerative condition marked by cognitive decline, memory loss, and loss of independence. Despite decades of extensive research, disease-modifying treatments have been limited in success. Recent therapeutic advancements have led to the development of monoclonal antibodies targeting amyloid-beta (Aβ) plaques, particularly the pyroglutamate-modified variant, a key pathological hallmark of AD. Objectives: This review aims to explore the therapeutic potential of Donanemab (Kisunla), a novel …
Published in Research and Reviews: A Journal of Neuroscience · Vol. 15, Issue 3, 2025 · pp. 37–45 Read article
-
Neurodiversity Revolution: Advancing Autism Therapies and Treating Comorbid Neurodegeneration
Abstract: The purpose of this study is to describe all about autism and for that it covered all the data included introduction, history, symptoms, diagnosis, treatment along with non-pharmacology therapies like play therapy, Behaviour therapy, ABA therapy, Occupational therapy, Speech therapy, Physiotherapy, and Sensory integration therapy. The neurodiversity movement recognizes autism as a natural variation of human neurodevelopment rather than a disorder to be cured or eliminated. Future approaches will likely …
Published in Research and Reviews: A Journal of Neuroscience · Vol. 13, Issue 1, 2023 · pp. 1–12 Read article
-
Mucormycosis: Review on the basis of Diagnosis Treatment, Preventive Measures, and Recent Research Approach
Abstract: Mucormycosis is a fungal infection called an angio-invasive disease due to invasion of fungi of the order Mucorales and zygomatic species which causes tissue infarction and necrosis. The main aim and purpose of this review are related to the overview of Etiopathogenesis of Mucormycosis, mortality due to various types of Mucormycosis, recent advances in diagnostic and treatment methods, and their diagnostic preventive measures. It shows serious and worrying mortality and …
Published in Research and Reviews : A Journal of Medical Science and Technology · Vol. 10, Issue 3, 2021 · pp. 51–62 Read article
-
Synthesis, Characterization of Mesoporous Zeolite BEA and Its Application in Multicomponent Reactions
Abstract: Strongly acidic mesoporous zeolite beta (MZB or Beta/MCM-41composite) with bimodal pore structure and stepwise distributed acidity has been synthesized by novel route using zeolite BEA as silica-alumina source. The material was characterized by various techniques. Powder XRD showed the existence of well-structured microphase zeolite Beta and mesophase MCM-41 in the composite materials. The performance of the composite material as a catalyst was investigated for the synthesis of various biologically active …
Published in Journal of Catalyst & Catalysis · Vol. 1, Issue 3, 2014 · pp. 25–45 Read article
-
Samelisant, an H3 Receptor Agonist as an Anti-Alzheimer Potential – A Pilot Study on Molecular Docking
Abstract: Neurodegenerative diseases have become more prevalent and about 55 million of the population are affected by dementia globally. One of the most important neurodegenerative diseases is Alzheimer’s disease which is known for its effect on memory and cognitive impairment. Alzheimer’s disease (AD) is an area of intense scientific investigation due to its high prevalence and the lack of a definitive cure. Amyloid precursor protein plays a central role in Alzheimer’s …
Published in International Journal of Brain Sciences · Vol. 3, Issue 1, 2026 · pp. 15–26 Read article
-
The Review of Beetroot Composition and Benefits of Beetroot
Abstract: The genus Beta L. comprises the red beetroot, which is linked to the Betoideae branch of the goosefoot family (Amaranthaceae). Because the tuberous root of the vegetable beetroot (Beta vulgaris L.) contains a large amount of nutrients, including vitamins and minerals as well as substances with physiological activity, including betalain, inorganic nitrates, polyphenols, and folates, it is consumed in every country around the world. Like its relative turnip, the beet …
Published in Research and Reviews : A Journal of Ayurvedic Science, Yoga and Naturopathy · Vol. 12, Issue 3, 2025 · pp. 35–42 Read article
-
Impact of Various Front-line Hypertensive medication on Blood Pressure Control During Maximum Exercise Testing in Coronary Artery Disease Patients
Abstract: It has long been known that blood pressure (BP) and cardiovascular morbidity are related. It is acknowledged that blood pressure during activity may serve as a more reliable indicator than resting blood pressure, which might not accurately reflect blood pressure at other times. Goals: 1) To assess how blood pressure behaves during physical activity in individuals with coronary artery disease (CAD) whose hypertension is managed with first-line antihypertensive medications. 2) …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 14, Issue 2, 2024 · pp. 37–41 Read article
-
Study of Tricalcium Phosphate Graft plus Platelet Rich Plasma in Bony Defects of Maxillofacial Area
Abstract: The present study was conducted at department of oral and maxillofacial surgery, career post-graduate institute of dental sciences and hospital, Lucknow with an objective to analyze the role of PRP in wound healing of maxillofacial defects along with beta-tricalcium phosphate as bone substitute and to compare the same with beta-tricalcium phosphate as bone substitute without PRP (Platelet Rich Plasma). A total of 30 subjects with maxillofacial bony defects were enrolled …
Published in Research and Reviews: A Journal of Dentistry · Vol. 7, Issue 1, 2016 · pp. 54–58 Read article
-
A molecular docking study and in silico analysis: targeting the marburg virus protein vp35 using active phytocompounds from alchemilla vulgaris
Abstract: Objective: The Marburg Virus Disease (MVD) is an infectious viral disease originating from African Fruit Bats (Rousettus aegyptiacus) that has become the root cause of a fatal hemorrhaging viral fever. As per reports from the WHO, MVD has claimed the lives of millions of people worldwide, with a disease fatality rate ranging from 24% in initial outbreaks to 88% in recent times owing to a difference in viral strains and …
Published in Research and Reviews : Journal of Computational Biology · Vol. 12, Issue 2, 2023 Read article
-
Combination Therapy with Propranolol and Cephalanoplos Segetum Against First Variceal Hemorrhage in Patients with Cirrhosis
Abstract: Background: Primary prophylaxis aims to prevent variceal hemorrhage in patients with esophageal varices who do not have a history of hemorrhage. The use of nonselective beta blockers is the first option for primary prophylaxis to prevent variceal bleeding in patients with the cirrhosis. Application of non-selective beta blocker has various kinds of merits, but patient's endurance to beta blocker becomes a problem and it does not prevent primary variceal bleeding …
Published in Research and Reviews: A Journal of Medicine · Vol. 12, Issue 1, 2022 · pp. 17–22 Read article
-
Cognitive Impairment in Alzheimer’s Disease
Abstract: Alzheimer's disease (AD) is a condition that leads to the deterioration of brain cells and is the primary cause of dementia, characterized by a decline in autonomy and cognitive function in day-to-day activities. The cholinergic hypothesis and the amyloid hypothesis are the two main theories proposed to explain AD's multifaceted nature. Characterized by a decline in autonomy and cognitive function in day-to-day activities. The cholinergic hypothesis and the amyloid hypothesis …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 16, Issue 3, 2026 Read article
-
A Pilot Study on β-lactamase Producing Escherichia coli from Bovine Milk, West Bengal
Abstract: Drug resistant bacteria have become a significant global healthcare issue that requires close attention. With regards to antibiotic resistance, E.coli and its Enterobacteriaceae family are highly notorious for their ability to swiftly spread antibiotic resistance genes, thereby posing a major concern. In order to effectively address the spread of multi drug resistant bacteria, ongoing monitoring of the microflora in milk for the presence of drug resistant genes is essential. This …
Published in International Journal of Toxins and Toxics · Vol. 1, Issue 1, 2024 · pp. 01–05 Read article
-
Green Synthesis of Copper Nanoparticle for the Treatment of Neurodegenerative Disease
Abstract: The study of ecologically friendly CuNP synthesis is a growing area with potential applications in biomedical research and environmental remediation, as well as sustainable nanotechnology. Generally, reducing, and stabilizing agents such as microbes, plant extracts, or other natural sources are used. The green synthesis methodology guarantees the production of nanoparticles with desired characteristics for biomedical applications while simultaneously mitigating the environmental effect that comes with conventional chemical processes. CuNPs possess …
Published in Research and Reviews : A Journal of Biotechnology · Vol. 14, Issue 1, 2024 · pp. 13–24 Read article
-
Effectiveness of Temporins for the Treatment of HPV Infections
Abstract: Objectives: Human papillomavirus (HPV), especially high-risk variants like type-16 have been linked to the formation of malignant tumors. HPV-16 has been implicated in most cases of cervical cancer in women. This study aims to assess the effectiveness of three types of temporin molecules, i.e., antiviral peptides secreted by certain frog species, for the inhibition of the viral L1 protein. Methods: In the present study, various computational tools were used to …
Published in International Journal of Cell Biology and Cellular Functions · Vol. 2, Issue 1, 2024 · pp. 41–53 Read article
-
Review: Virulence factors, resistance genes and pathogenicity of Moraxella catarrhalis
Abstract: An estimated 2-4 million cases of chronic obstructive pulmonary disease(COPD) in adults are exacerbated by Moraxella catarrhalis annually in the US, making it a pathogen of increasing significance for respiratory tract infections. It often colonizes the nasopharynx without causing any symptoms and an opportunistic bacterial infection of the respiratory mucosa that is exclusive to humans. In our study, we reviewed references about the important virulence factors that M. catarrhalis possess …
Published in Recent Trends in Infectious Diseases · Vol. 2, Issue 1, 2025 · pp. 33–40 Read article
-
Strategy to Accelerate the Biopharmaceuticals Production Using Komogataella phaffii (Pichia pastoris)
Abstract: Revenue generation has been the primary goals for nations as well as the industries worldwide. Biopharmaceutical verticals have become potential revenue generators as they are the industrial workhorses and the economic engines that drive the upcoming biopharmaceutical industries with advances in DNA recombinant technology. A breakthrough in the indusrial biotechnology for the production of biopharmaceuticals using Pichia pastoris is awaited. Ablynx NV, Recombinant proteins (RP), HSA-pFSH beta, antibodies, borosin, N-glycoprotein, …
Published in International Journal of Advance in Molecular Engineering · Vol. 2, Issue 2, 2024 · pp. 1–7 Read article
-
Identification of ESBL producing Escherichia coli from Urine Samples at Tertiary Care Hospital in Jhalawar
Abstract: Introduction: Antibiotic resistance (ABR) is a serious worldwide threat to public health due to the emergence of multidrug resistant bacteria and is considered as a great problem in the treatment of bacterial infections both in hospital as well as community settings. Extended Spectrum Beta-Lactamase (ESBL) producing strains have emerged as a significant challenge to counter with present antibiotics. Aims: Our study was aimed to know the prevalence of ESBL producing …
Published in Research and Reviews: A Journal of Microbiology and Virology · Vol. 7, Issue 3, 2017 · pp. 38–45 Read article