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76 articles for “mucositis”
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A Thorough Analysis of Herbal and Synthetic Methods for Treating Peptic Ulcers
Abstract: Many people are afflicted with ulcers, a common gastrointestinal disorder. In essence, they are inflammatory lesions that form in the digestive tract's skin or mucous membrane lining. An imbalance between preventive and damaging factors—either from reduced mucosal defences or from increased aggressive elements—leads to ulcer development. Their development is influenced by a number of variables, including as stress, poor eating habits, and long-term pharmaceutical use. The word "peptic ulcers" refers …
Published in Research & Reviews: A Journal of Drug Formulation, Development and Production · Vol. 12, Issue 2, 2025 · pp. 55–71 Read article
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Advancements in Buccal Patch Drug Delivery Systems: A Comprehensive Review of Evaluation Parameters
Abstract: The most dependable delivery method is buccal patches because it offers many improvements over alternative methods.This delivery method circumvents the hepatic first pass metabolism to deliver the medication into the systemic circulation. Buccal patches are inserted between the cheek and gums, where they dissolve and absorb through the buccal cavity's mucosal membrane. Polymers can be used to control the drug's delivery, and intelligent polymeric systems are a good option for …
Published in OmniScience: A Multi-disciplinary Journal · Vol. 15, Issue 2, 2025 Read article
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Extragingival Pyogenic Granuloma: A Common Lesion in an Uncommon Location
Abstract: Reactive lesions of the oral mucosa are benign and common entities which occur with greater frequency. When the same lesions occur in uncommon sites, they may pose a challenge in diagnosis. One such lesion is the extragingival pyogenic granuloma, which is a counterpart of the most common reactive lesion, the pyogenic granuloma. A case of extragingival pyogenic granuloma occurring on the buccal mucosa of an elderly patient is being presented. …
Published in Research and Reviews: A Journal of Dentistry · Vol. 9, Issue 2, 2018 · pp. 16–19 Read article
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The Safety of Dental X-ray Machine against the Deoxyribonucleic Acid (DNA): In Vitro Model Explores the Effects of Chlorine Free Radical, Duration of Exposure and the Doses of Irradiation
Abstract: Background: Patients attended to the dental clinics are referred to X-ray which may arise the possibility of adverse reactions upon oral mucosa. X-ray-induced oral mucosa damage is related to the generation of the free radicals in the aqueous media of the cells. Objectives: This study aimed to clarify the safety of dental X-ray exposure by utilizing an in vitro experimental model of calf-thymus double strands DNA (ctdsDNA) molecule exposed to …
Published in Research and Reviews: A Journal of Dentistry · Vol. 10, Issue 2, 2019 · pp. 23–28 Read article
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Comparison of the Accuracy of the Computer-guided Surgery with Different Templates
Abstract: The advent of computed tomography and the development of new pre-surgical programming software has completely revolutionized the surgical approach in dentistry. Through virtual study, it is possible to program the surgery with the aim of obtaining a surgical guide that allows for the insertion of an implant in the ideal position. The purpose of this study is to evaluate the different accuracies obtained using different surgical guides. 16 implants were …
Published in Research and Reviews: A Journal of Dentistry · Vol. 14, Issue 1, 2023 · pp. 18–27 Read article
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Molecular Identification of Common Bacterial Infection in Chronic Otitis Media in an Outpatient Department of Tertiary Care Hospital
Abstract: Chronic otitis media (COM) is a chronic inflammation of the mucoperiosteum of the middle ear left which leads to profuse discharge from the ear and hearing impairment that may have a serious long-term effect on language, auditory and cognitive development and on educational progress. In the present study, the prevalence of culture-positive cases of an active mucosal variety of COM was 92.65%. Pseudomonas aeruginosa (41.2%) was the predominant aerobic bacterial …
Published in Research and Reviews : A Journal of Medical Science and Technology · Vol. 8, Issue 1, 2019 · pp. 18–24 Read article
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Systematic Review on: Peptic Ulcer and Its Management
Abstract: Peptic ulcer disease (PUD), which affects 5–10% of people worldwide, is still a significant global health concern. Gastric acid and pepsin's corrosive effects cause mucosal injury in the stomach, duodenum, or lower oesophagus. Long-term use of nonsteroidal anti-inflammatory drugs (NSAIDs) and Helicobacter pylori infection are the primary reasons. This review's goal is to examine PUD's aetiology, risk factors, pathophysiology, clinical symptoms, diagnostic methods, and evidence-based treatment modalities. PubMed, Google Scholar, …
Published in Research and Reviews : A Journal of Life Sciences · Vol. 16, Issue 1, 2026 · pp. 60–64 Read article
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Molecular Docking Study: Targeting mycobacterium leprae ML2640 Protein Using Active Compounds from Coscinium fenestratum
Abstract: Objectives: Leprosy is an infectious disease in skin, peripheral nerve and mucosa of upper airway. Around 70% of this infection is caused by Mycobacterium leprae, which was discovered during1873. Multi drug therapy is used for the treatment, still multiple drug resistance and reactions has been reported among patients. Hence, this work focused on identifying bioactive compounds from Coscinium fenestratum that can target mycobacterium leprae ML2640 protein by in-silico approach. Method: …
Published in International Journal of Genetic Modifications and Recombinations · Vol. 1, Issue 2, 2023 · pp. 21–33 Read article
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Fast Dissolving Oral Thin Films: A Review
Abstract: Fast-dissolving oral thin films (FDOFs) represent a significant advancement in drug delivery technology, offering advantages over traditional solid dosage forms, especially for patients with swallowing difficulties. FDOFs dissolve rapidly in the mouth, releasing the active ingredient without the need for water or chewing. They have picked up ubiquity due to their comfort, taste veiling capabilities, and progressed persistent compliance. Ideal drugs for FDOFs should possess characteristics such as solubility, stability, …
Published in Research & Reviews: A Journal of Drug Design & Discovery · Vol. 11, Issue 1, 2024 · pp. 24–31 Read article
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Exploring the Pathophysiology of Henoch-Schönlein Purpura (HSP): A Comprehensive Review
Abstract: Blood from tiny veins can leak into nearby tissues, causing purpura, a disorder marked by red spots or patches on the skin that may have an impact on the kidneys. Henoch-Schönlein purpura (HSP) is associated with vasculitis and inflammation of blood vessels. The range of renal conditions associated with purpura includes severe glomerulonephritis and mild proteinuria. For instance, immunological complex accumulation in the renal glomeruli of HSP patients might result …
Published in International Journal of Cell Biology and Cellular Functions Read article
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Examining Connective Tissue Changes Across Various Grades of Oral Epithelial Dysplasia and Oral Squamous Cell Carcinoma: A Histochemical Polymeric Investigation
Abstract: Oral epithelial dysplasia (OED) and oral squamous cell carcinoma (OSCC) represent a spectrum of potentially malignant disorders posing significant challenges in diagnosis and management. The tumor microenvironment, particularly alterations in the connective tissue, plays a crucial role in the progression of these lesions. This histochemical investigation comprised with embedded polymers aimed to examine connective tissue changes across various grades of oral epithelial dysplasia (OED) and oral squamous cell carcinoma (OSCC). …
Published in Journal of Polymer & Composites · Vol. 12, Issue 3, 2024 · pp. 124–137 Read article
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An Effective & Novel Approach as Gastro-retentive Drug Delivery Systems
Abstract: Researcher’s curiosity about gastro-retentive drug delivery system increased so high in recent years because of its excellent drug releasing properties to the target site. The delivery system's residence time in the stomach can be extended with the usage of gastro-retentive drug delivery system by using a number of natural and synthetic polymers such as guar gum, hydoxy propyl methyl cellulose which can be used to improve the bioavailability of a …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 15, Issue 2, 2024 · pp. 47–54 Read article
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Role of Gastric Receptors in Gastrointestinal Disorder
Abstract: The established and potential roles of cholecystokinin1 and cholecystokinin2 receptors in gastrointestinal and metabolic diseases are analyzed, along with findings from human studies involving agonists and antagonists. While there is considerable evidence implicating cholecystokinin1R in various diseases such as pancreatic disorders, motility disorders, tumor growth, satiety regulation, and cholecystokinin-deficient states, its specific role in these conditions remains ambiguous. Conversely, the role of cholecystokinin2R in physiological (e.g., atrophic gastritis) and pathological …
Published in International Journal of Biomedical Innovations and Engineering · Vol. 2, Issue 2, 2024 · pp. 37–49 Read article
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Oral Thin Films of Ondanetron Hcl: Formulation and Performance Evaluation
Abstract: This study had the goal to formulate oral polymeric thin film that would dissolve and disintegrate instantly, while also having high mechanical features. These are the most advanced forms of solid dosage forms. Solvent casting was the technique employed to create oral thin films. These are additionally referred to as buccal films/strip, mouth dissolving films, oral thin films, as well as oral strips of paper. These films are suitable for …
Published in Research & Reviews: A Journal of Drug Design & Discovery · Vol. 11, Issue 3, 2024 · pp. 1–6 Read article
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Review: Virulence factors, resistance genes and pathogenicity of Moraxella catarrhalis
Abstract: An estimated 2-4 million cases of chronic obstructive pulmonary disease(COPD) in adults are exacerbated by Moraxella catarrhalis annually in the US, making it a pathogen of increasing significance for respiratory tract infections. It often colonizes the nasopharynx without causing any symptoms and an opportunistic bacterial infection of the respiratory mucosa that is exclusive to humans. In our study, we reviewed references about the important virulence factors that M. catarrhalis possess …
Published in Recent Trends in Infectious Diseases · Vol. 2, Issue 1, 2025 · pp. 33–40 Read article
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A Comprehensive Review on Monkeypox Infection
Abstract: Monkeypox represents a zoonotic viral affliction instigated by the monkeypox virus, which is classified within the Poxviridae family and is distinct from the virus that causes chickenpox. Initially recognized in 1958, this infection has recently attracted international scrutiny due to its escalating incidence beyond traditional endemic territories. This review delivers an exhaustive examination of monkeypox, encompassing its epidemiology, viral morphology, modes of transmission, pathogenesis, clinical presentations, and therapeutic interventions. The …
Published in Recent Trends in Infectious Diseases · Vol. 2, Issue 1, 2025 · pp. 23–32 Read article
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A Quasi-Experimental Investigation of The Effects of Two Different Negative Pressure Levels During Open Endotracheal Tube Suctioning on Physiological Parameters in Mechanically Ventilated Patients in The PCCM ICU At Pt. B.D. Sharma P.G.I.M.S., Rohtak
Abstract: Introduction: Patients who are intubated often have difficulty clearing secretions through coughing. As a result, endotracheal suctioning is essential to minimize the risk of consolidation and atelectasis, which could impair ventilation. However, suctioning can pose several risks and complications, including bleeding, infection, atelectasis, hypoxemia, cardiovascular instability, increased intracranial pressure, and potential damage to the tracheal mucosa. The level of negative pressure applied during suctioning plays a crucial role in the …
Published in International Journal of Emergency and Trauma Nursing and Practices · Vol. 2, Issue 2, 2024 · pp. 29–58 Read article
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Mind-Gut Connection: The Psychosomatic Effects of Stress and Emotions on Digestive System
Abstract: Stress, understood as an immediate disruption to bodily equilibrium, triggers an adaptive or allostatic response that impacts gastrointestinal function both in the short and long term. The enteric nervous system communicates in both directions with the brain through parasympathetic and sympathetic pathways, collectively forming what is known as the brain-gut axis. Unani scholars describe stress as a response to the loss of something valuable, such as an opportunity, a desired …
Published in Research and Reviews: A Journal of Neuroscience · Vol. 15, Issue 1, 2025 · pp. 11–14 Read article
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Therapeutic Potential of Terminalia arjuna Bark in the Management of Hemorrhoids: A Comprehensive Review
Abstract: Background: Hemorrhoids appear frequently among anorectal disorders since they create vascular swelling together with pain symptoms, while leading to bleeding and mucosal tissue tending to slide out. Though effective therapy exists, traditional treatments produce various adverse effects and lead to recurrence and inconsistent patient following of medical recommendations over the long term. Plantbased therapeutic medicines have gained rising demand, which leads experts to investigate medicinal plants with established pharmacological effects. …
Published in Research & Reviews: A Journal of Pharmacognosy · Vol. 12, Issue 2, 2025 · pp. 22–32 Read article
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Orally Dispersible Tablet of Mesalazine: Formulation and Evaluation
Abstract: Oral disintegrating tablets (ODTs) become increasingly more and more popular, particularly among elderly and paediatric patients who have difficulties with swallowing. The 5-aminosalicylic acid compound oral mesalazine, frequently referred to as mesalamine, is used to treat mild to severe ulcerative colitis and has a high percentage of success in causing and establishing response. Mesalazine has a topical therapeutic action at the location of the suffering colonic mucosa. The medication’s disadvantage …
Published in Research & Reviews: A Journal of Drug Formulation, Development and Production · Vol. 12, Issue 2, 2025 · pp. 16–25 Read article