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166 articles for “markers”
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Comparative Evaluation of Pedigree-Based and Genomic BLUP Models for Wheat Grain Yield Prediction
Abstract: Before genome-wide molecular markers became affordable, plant and animal breeding relied on pedigree-based prediction (P-BLUP), using the expected additive relationship matrix (A) derived from recorded ancestry. Genomic selection replaced or augmented this with a marker-derived genomic relationship matrix (G; GBLUP), and single-step methods combining A and G are now standard when only a subset of a breeding population is genotyped. It is less clear whether pedigree information retains any predictive …
Published in Research and Reviews : Journal of Computational Biology · Vol. 15, Issue 2, 2026 · pp. 1–9 Read article
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Genetic Diversity and Characterization of Ocimum sanctum Collected from Anand, Central Gujarat Region, by PCR-based RAPD Markers
Abstract: Genetic relationships were examined among thirty germplasm accessions belonging to ten Ocimum species using RAPD markers. A very high degree of polymorphism (98.92%) was observed. UPGMA cluster analysis of genetic similarity indices grouped all the accessions into two major clusters corresponding to previously reported botanical sections. Intra-clustering within the two clusters precisely grouped the accessions belonging to one species in onesub-cluster as expected from their genetic background. Results of this …
Published in Research and Reviews: A Journal of Microbiology and Virology · Vol. 3, Issue 2, 2013 · pp. 6–12 Read article
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Comparative Evaluation of GPBB and CK-MB in Early Diagnosis of Acute Myocardial Infarction in Diabetic and Non-Diabetic Patients
Abstract: Background: Acute myocardial infarction (AMI) continues to be a leading cause of morbidity and death among people worldwide. To lower the risk of problems, early and precise diagnosis is essential, particularly for diabetes patients. The study investigates the diagnostic value of Glycogen Phosphorylase BB (GPBB), a potential early biomarker of myocardial necrosis, and compares it with CK-MB, a widely used cardiac marker, in AMI diagnosis. Inflammatory markers (hs-CRP, IL-6, TNF-α) …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 16, Issue 2, 2025 · pp. 33–37 Read article
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Mass Spectrometry–Based Phosphoproteomic Markers to Predict Kinase Inhibitor Response in Solid Tumors
Abstract: Mass spectrometry-based phosphoproteomics has emerged as a powerful tool for predicting kinase inhibitor responses in solid tumors, offering direct functional insights into signaling pathways that surpass traditional genomic profiling by capturing dynamic kinase activities and adaptive resistance mechanisms. Technological breakthroughs, including data- independent acquisition (DIA), trapped ion mobility spectrometry (timsTOF), and efficient enrichment methods like TiO2 or IMAC, now enable comprehensive profiling of over 40,000 phosphorylation sites from limited clinical …
Published in International Journal of Cell Biology and Cellular Functions · Vol. 4, Issue 2, 2026 Read article
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Sublethal Toxic Effect of Paraquat Dichloride on Tissue Biochemical Markers in Labeo rohita
Abstract: The present study investigated the sublethal toxic effect of the commercial grade herbicide, Paraquat dichloride (24% SL), on Labeo rohita stressing the importance on biochemical parameters. Fishes were exposed to the sublethal concentrations of paraquat dichloride (5 μg/l and 10 μg/l) for 24 h in treated groups. Treated groups showed highly changed biochemical parameters on their exposure to the herbicide paraquat, when compared to the control. Tissues such as brain, …
Published in Research and Reviews : A Journal of Life Sciences · Vol. 11, Issue 2, 2021 · pp. 20–28 Read article
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Serum Magnesium, Iron, TIBC, and Hormonal Imbalances in Hypertensive Pregnant Women: A Comparative Study
Abstract: Pregnancy-induced hypertension (PIH), including gestational hypertension and preeclampsia, is a leading cause of maternal and fetal complications. The regulation of blood pressure and overall pregnancy health is influenced by micronutrients and hormones. This study aimed to evaluate serum magnesium, serum iron, total iron binding capacity (TIBC), thyroid profile, and quadruple marker levels in hypertensive pregnant women and compare them to normotensive controls. Methods: A total of 1056 hypertensive pregnant women …
Published in Research and Reviews : A Journal of Medical Science and Technology · Vol. 14, Issue 2, 2024 · pp. 41–45 Read article
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Performance Evaluation of Segmentation Algorithms for Apple Fruit Grading
Abstract: For supplying high-quality food products within a short time, automated grading of fruits is getting special attention. Fruit grading technique will grade the fruits using their shapes, color and outer look. This emphasizes the necessity of image segmentation which extracts important features from an image. This paper consists of analysis of different segmentation algorithms for detecting damage part of fruit. Marker-based watershed algorithm uses internal and external markers to locate …
Published in Journal of Image Processing & Pattern Recognition Progress · Vol. 1, Issue 2, 2014 · pp. 34–40 Read article
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Extra Philadelphia in CML Due to Isodicentric 22: A Case Report
Abstract: Introduction: Chronic Myelogenous Leukemia is a malignancy that affects the hematopoietic stems cells (HSC) of the bone marrow, leading to the rapid and continual proliferation of granulocytes and precursor blast cells. This is caused due to a reciprocal translocation that occurs between chromosomes 9 and 22, leading to the formation of derivative 22 also called as Philadelphia (Ph) chromosome. The Ph chromosome then encodes a fusion oncoprotein that functions as …
Published in Research and Reviews: Journal of Oncology and Hematology · Vol. 14, Issue 3, 2025 · pp. 18–22 Read article
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Phyto-Pharmacognostical Study of Zornia Gibbosa Span (Samyojaki)
Abstract: Recent survey shows that the plants extinction are occurring at rates hundreds of times higher than natural background rates, and 15,000 species of medicinal plants are now threatened. Under such circumstances the drugs which are abundantly available, common and cost-effective should be encouraged to control the extensive overuse of few classical drugs. Thus preventing them from verge of extinction and also reducing the chances of adulteration. Looking at the need …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 3, Issue 3, 2013 · pp. 24–32 Read article
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Environmental Impact of Ghaf Tree (Prosopis cineraria) on Heavy Metals Concentration in Atmosphere
Abstract: The Ghaf is a hardy tree, drought-resistant, and can grow up to ten meters in height, it tree produces small, yellow flowers which attractive to many habitats, like bees, insects, and birds. The leaves and pods of the Ghaf tree have significant antioxidant and anti-inflammatory properties and can be used in new drug development. Ghaf trees can adapt to changing environmental conditions and planting Ghaf trees could be an effective …
Published in International Journal of Minerals · Vol. 1, Issue 1, 2024 · pp. 1–7 Read article
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Evaluating the Role of Platelet Indices, with a Focus on Immature Platelet Fraction (IPF), in Differentiating Hyper-Destructive and Hypo-Productive Thrombocytopenia: A Study from Ludhiana, Punjab, India
Abstract: Background: Thrombocytopenia, characterized by a reduction in platelet count, is commonly observed in clinical settings. Its etiology can be broadly classified into hyper-destructive thrombocytopenia, where platelets are destroyed at an accelerated rate, and hypo-productive thrombocytopenia, where platelet production is impaired. Differentiating between these two causes is essential for effective management. The Immature Platelet Fraction (IPF) has emerged as a promising non-invasive diagnostic tool to distinguish these causes. Objectives: The primary …
Published in Research and Reviews: Journal of Oncology and Hematology · Vol. 14, Issue 2, 2025 Read article
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Modern Vaccines with DIVA Capability: An Overview
Abstract: DIVA vaccines are designed to achieve twin-goals of the immunological protection of the host and the immunological differentiation of the infected from the vaccinated animals (DIVA) with a companion immunodiagnostic test. The DIVA strategy is used in countries that follow the vaccination path for elimination of an infectious disease and ultimately to achieve the disease-free status for international trade. This strategy has also been advocated for and adopted in the …
Published in Research and Reviews : A Journal of Immunology · Vol. 5, Issue 1, 2015 · pp. 1–12 Read article
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Clinical Significance of Immune Cells and T-cell Subsets in Lung Cancer
Abstract: Objectives: The aim of the study was to determine the clinical usefulness of pretreatment hematological parameters including neutrophils, lymphocytes, monocytes and immune T-cell subsets as well as calculated coefficients such as neutrophils-to-lymphocytes ratio(NLR),monocytes-to-lymphocytes ratio(MLR) and platelets-to-lymphocyte ratio(PLR)in patients with lung cancer. Materials and Methods: A total of 102 patients with lung cancer were prospectively analyzed. T-cell subsets were assessed by flow cytometry method. Peripheral blood was collected from 25 healthy …
Published in Research and Reviews : A Journal of Immunology · Vol. 9, Issue 2, 2019 · pp. 14–29 Read article
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Atypical Psychiatric Presentations of Autoimmune Encephalitis: A Case Series and Proposed Clinical Approach to Diagnosis
Abstract: Background: knowledge and detection of seronegative autoimmune encephalitis (AE) is growing rapidly, but typical psychiatric presentations risk misdiagnosis or delay in diagnosis with worse prognostic outcomes. Paraclinical markers are useful when positive, and integral to the current diagnostic framework yet have limited sensitivities leaving an unknown percentage of patients without diagnosis or treatment. Cases not meeting diagnostic criteria pose a particular clinical challenge regarding diagnosis and treatment decision making and …
Published in Research and Reviews: A Journal of Neuroscience · Vol. 12, Issue 2, 2022 · pp. 26–37 Read article
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Augmented Reality Based Atlas of India
Abstract: A technology known as augmented reality (AR) fuses the actual environment with a virtual item, whether it be in two dimensions (2D) or three dimensions (3D), in real time. The advancement of augmented reality (AR) technology has made significant contributions to several sectors, one of which is the use of AR for academic purposes. The proposed system can help students and peoples to explore the different map in real time. …
Published in Journal of Multimedia Technology & Recent Advancements · Vol. 9, Issue 2, 2022 · pp. 1–7 Read article
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¬Study on Phenological, Qualitative and Quantitative Traits in Fodder Maize (Zea mays L.): Digestible Nutrients and Chemical Composition
Abstract: AbstractThe present study examined the effectiveness of maize fodder cultivated with three genotypes— V1 (AAIMS 1), V2 (AAIMS 2), and V3 (J1006) in fodder maize, obtained from complete randomized design in the Animal Nutrition Laboratory, SHIATS, Allahabad, India. The data were recorded on eight characters to study the per se performance of fodder quality traits of maize fodder. Analysis of variance revealed that there was considerable variation available for most …
Published in Research & Reviews : Journal of Agricultural Science and Technology · Vol. 3, Issue 2, 2014 · pp. 24–29 Read article
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Study on Phenological, Qualitative and Quantitative Traits in Fodder Maize (Zea mays L.): Seed Quality Measurement
Abstract: AbstractThe investigation consists of three genotypes (AAIMS 1, AAIMS 2 and J1006) of maize, obtained from Department of Genetics and Plant Breeding, SHIATS Allahabad, Uttar Pradesh and P.A.U Ludhiana, Punjab. The experiment was conducted during kharif 2010 in field having Randomized Block Design with three replications and in the Post graduate laboratory of the Department of Genetics and Plant Breeding, Allahabad School of Agriculture, SHIATS Allahabad, Uttar Pradesh, respectively. The …
Published in Research and Reviews : Journal of Crop science and Technology · Vol. 3, Issue 1, 2014 · pp. 8–11 Read article
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Genetic Diversity of Wheat (Triticum aestivum L.) Germplasm
Abstract: The present investigation was conducted to examine the genetic diversity existing among 30 genotypes of wheat. The experimental design used was randomized block design having four replications. The study revealed wide range of variability and high heritability for all the traits. High estimates of genotypic coefficient of variation (GCV) and phenotypic coefficient of variation (PCV) were observed for number of tillers per plant and yield per plant. High heritability coupled …
Published in Research and Reviews : Journal of Crop science and Technology · Vol. 2, Issue 2, 2013 · pp. 26–36 Read article
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A Pilot Study on β-lactamase Producing Escherichia coli from Bovine Milk, West Bengal
Abstract: Drug resistant bacteria have become a significant global healthcare issue that requires close attention. With regards to antibiotic resistance, E.coli and its Enterobacteriaceae family are highly notorious for their ability to swiftly spread antibiotic resistance genes, thereby posing a major concern. In order to effectively address the spread of multi drug resistant bacteria, ongoing monitoring of the microflora in milk for the presence of drug resistant genes is essential. This …
Published in International Journal of Toxins and Toxics · Vol. 1, Issue 1, 2024 · pp. 01–05 Read article
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Genetics of Bipolar Disorder: A Review
Abstract: Bipolar disorder is a complex psychiatric condition that is thought to have a significant genetic component. This article explores the genetic basis of bipolar disorder, including the potential genetic risk factors and the biological mechanisms that contribute to the development of this disorder. The article discusses the various genetic studies that have been conducted to identify genes and genetic variants associated with bipolar disorder, including genome-wide association studies (GWAS) and …
Published in Research & Reviews: A Journal of Bioinformatics · Vol. 10, Issue 1, 2023 · pp. 23–28 Read article