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42 articles for “lung’s cells”
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Immunohistochemical Detection of c-Myc in Lungs of Sheep with Ovine Pulmonary Adenocarcinoma
Abstract: vine pulmonary adenocarcinoma, a naturally occurring lung cancer of sheep was diagnosed in seventeen cases at slaughter houses. Lung tumor tissues and associated lymph nodes were collected for histopathological and immunohistochemical studies. Histologically, the lung sections from OPA cases revealed areas of non encapsulated proliferation of alveolar epithelial cells in papillary or acinar pattern. Polyploid ingrowths were also noticed into the bronchioles. On immunostaining of lung sections, JSRV-MA protein was …
Published in Research and Reviews : Journal of Veterinary Science and Technology · Vol. 4, Issue 2, 2015 · pp. 13–17 Read article
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Antibacterial, Cytotoxicity Studies of Azukia mungo (L.) Masam and Correlation with in silico Docking Studies
Abstract: Introduction and Background: Azukia genus plants rich in proteinaceous anti-nutrients like tannins (especially condensed tannins) has been shown to have anti-bacterial activity against Staphylococcus aureus and antineoplastic activity against lung and liver cancer cells. Five types of procyanidins (condensed tannins) have already been isolated from Azukia mungo and structurally elucidated. But its activity against the Methicillin resistant Staphylococcus aureus (MRSA) has not yet been shown. Hence we focus our work …
Published in Research and Reviews: A Journal of Toxicology · Vol. 7, Issue 2, 2017 · pp. 21–31 Read article
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Non -Invasive Ways to Detect Cancer
Abstract: Cancer is a diverse group of diseases characterized by uncontrolled cell growth and division, affecting millions worldwide and being a leading cause of death. The disease typically involves genetic alterations that disrupt the normal balance of cell growth, leading to the formation of tumors. Tumors can be benign, posing no threat as they do not spread, or malignant, capable of invading nearby tissues and metastasizing. There are more than 100 …
Published in Research and Reviews : A Journal of Life Sciences · Vol. 14, Issue 2, 2024 · pp. 59–67 Read article
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Soo-ul-Qiniya (Iron Deficiency Anaemia): Historical Succinct Review
Abstract: Anaemia or Iron deficiency anaemia is a widespread health issue that affects millions of people worldwide. Anemia is a state in which the body lacks sufficient haemoglobin, a protein located in red blood cells responsible for transporting oxygen from the lungs to various tissues of the body. This lack of haemoglobin can result in a decrease in the concentration of haemoglobin in the blood or a reduced percentage of haemoglobin …
Published in Research and Reviews : A Journal of Life Sciences · Vol. 13, Issue 2, 2023 · pp. 25–28 Read article
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Lung Cancer Detection and Classification Using Deep Learning
Abstract: Lung cancer is a disease that can be effectively treated if detected early. Various technologies, such as magnetic resonance imaging, isotopes, X-rays, and computed tomography scans, are employed for diagnosis. One of the most crucial strategies in combating cancer is early detection, which greatly enhances a patient’s likelihood of survival; this is where artificial intelligence plays a significant role. The approach proposed in this study leverages historical medical data to …
Published in Research and Reviews: Journal of Oncology and Hematology · Vol. 13, Issue 3, 2024 · pp. 11–17 Read article
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Menstrual Blood Banking: A Future Need and Scope
Abstract: Stem cells abundant in menstrual blood possess the capacity to develop and differentiate into various cell types. The regenerative capacity of these stem cells derived from menstrual blood is comparable to that observed in stem cells present in umbilical cord blood and bone marrow. Every healthy woman experiences menstruation on average once every 28 to 30 days from the time of menstruation till menopausal. Menstrual blood banking involves storing menstrual …
Published in Research and Reviews : A Journal of Medical Science and Technology · Vol. 12, Issue 2, 2024 · pp. 35–39 Read article
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Exploring the Role of MAPK3 in Major Depressive Disorder: Molecular Docking, Dynamics, and Binding Free Energy Analysis of Natural Compounds as Alternatives to Conventional Drugs
Abstract: Major Depressive Disorder (MDD) is a prevalent neuropsychiatric disorder with limited treatment efficacy and significant side effects associated with conventional antidepressants. Recent studies have highlighted the role of mitogen-activated protein kinase 3 (MAPK3) in the mechanisms underlying MDD, positioning it as a potential target for the development of novel therapeutic drugs. In this study, we employed various computational approaches to explore natural compounds as viable alternatives to synthetic antidepressants. Researchers …
Published in International Journal of Bioinformatics and Computational Biology · Vol. 3, Issue 2, 2025 · pp. 53–68 Read article
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Network Pharmacology and Molecular Docking Approach to Reveal the Underlying Mechanisms of Isorhamnetin in the Treatment of Lymphangitis Carcinomatosis
Abstract: Objective: Lymphangitic carcinomatosis (LC) is a tumor that spreads through lung lymphatics and is most commonly seen secondary to adenocarcinoma. In the majority of cases, LC is a result of tumor cells spreading through the lymphatic system. However, approximately 20% of LC cases can be attributed to lymphangitis caused by tumors obstructing lymphatic drainage. This blockage commonly occurs near the lung hilum, where a centrally located mass can cause inflammation …
Published in International Journal of Bioinformatics and Computational Biology · Vol. 1, Issue 1, 2023 · pp. 28–45 Read article
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Unusual Distant Metastasis in Buccal Squamous Cell Carcinoma: A Case Report
Abstract: Head and neck squamous cell carcinomas (SCC) are known to have high loco regional recurrence with distant mets being rare. However, distant metastasis are showing an increasing trend due to the improved locoregional control rates achieved with surgery and radiotherapy. The usual sites of distant failure are lung, liver, bone, adrenal, heart and kidney. Here is presented a case of buccal SCC presenting with unusual distant soft tissue mets after …
Published in Research and Reviews: Journal of Oncology and Hematology · Vol. 3, Issue 2, 2014 · pp. 15–17 Read article
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Diabetic Level Prediction in Humans: Using Supervised Machine Learning Methods
Abstract: Diabetes could be an unremitting malady or a metabolic sick wellbeing cluster where an individual endures from a pervasive sum of insulin-producing blood glucose within the body or since the cells of the body do not react to affront. Steady diabetes hyperglycemia is the damage to long term organs, particularly lungs, kidneys, nerves, the heart and the veins are connected to weakness and misfortune. The objective of this investigation is …
Published in Recent Trends in Parallel Computing · Vol. 7, Issue 1, 2020 · pp. 1–6 Read article
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Therapeutic Effects of Metformin on Cancer: A Possible Option in Cancer Chemotherapy
Abstract: Metformin is being used for an elongated period of an antidiabetic medicine for type 2 diabetes. It is used moreover as a monotherapy or in mixture with additional antidiabetic medications. The drug derived into importance in diabetes and other circumstances with cardiovascular risk after the landmark study of 1995 by the United Kingdom Prospective Diabetes Study which highlighted its reputation. The usage of metformin, the usually given drug for type …
Published in Research & Reviews: A Journal of Drug Design & Discovery · Vol. 8, Issue 1, 2023 · pp. 46–68 Read article
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Mirabilis Jalapa Flower Extract as Natural Food Dye and Green Cellular Delivery of Nanoparticles
Abstract: Use of artificial colouring agents in sweets and packed food has become a common scenario now a day, which pose serious consequences in consumers especially children. Various studies around the globe reported the serious health hazards of artificial food dyes which include organ damage of liver, kidney and lungs thereby affecting metabolic enzymes, serum creatine and urea levels and brain damage resulting in neurotoxicity and even behavioural deficits in children. …
Published in Research & Reviews: A Journal of Drug Design & Discovery · Vol. 8, Issue 2, 2023 · pp. 27–34 Read article
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THE EVOLVING ROLE OF ARTIFICIAL INTELLIGENCE (AI) IN THE DISCOVERY OF CANCER DRUG THERAPY
Abstract: The term "cancer" refers to a broad range of diseases that develop in any organ or tissue of the body when malignant cells multiply out of control, cross their usual boundaries to infect surrounding body regions, and spread to other organs, primarily problems that arise in breast cancer and lung cancer. The world recognizes Artificial Intelligence (AI) as a cutting-edge technology. Today, several institutes, organizations, and individuals are aiming to …
Published in Research & Reviews: A Journal of Drug Formulation, Development and Production · Vol. 10, Issue 1, 2023 · pp. 74–87 Read article
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Effect of Nicotine on Cytokine Production by Human Mononuclears: Perspective of COVID-19
Abstract: Nicotine is present in the tobacco-containing products such as cigars, cigarettes, chewing tobacco, snus (an oral tobacco) and pipe tobacco. In Indian population, nicotine containing products are consumed by the 57% of population either in chewing form or smoking form. The correlation of nicotine and lung cancer in chronic smokers as well as nicotine consumption and COVID-19 incidence has to be justified. Hence current research was carried to study the …
Published in Research and Reviews : A Journal of Immunology · Vol. 11, Issue 1, 2021 · pp. 8–11 Read article
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Diagnostic Methods for Hepatitis-C Virus and Tuberculosis Coinfection among HIV Infected Individuals: A Review
Abstract: HIV is the chronic viral infection documented worldwide. HIV virus infects and destroys helper T cells (CD4) leading to a number of immunological deficiencies among which Hepatitis-C Virus (HCV) and Tuberculosis (TB) are the major. HCV is a RNA virus that infects the liver leading to cirrhosis, hepatocellular carcinoma and is a leading cause of deaths in HIV/HCV co-infected patients. Tuberculosis, the most common opportunistic infection in HIV positive patients, …
Published in Research and Reviews: A Journal of Microbiology and Virology · Vol. 6, Issue 3, 2016 · pp. 38–41 Read article
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Flavonoids Regulate Airway MUC5AC Mucin Expression through Modulation of Multiple Signalling Pathways
Abstract: Airway mucus is a component of pulmonary innate immune function and plays very important role in defense against invading pathogenic microbes, chemicals and particles. The protective function of airway mucus is attributed to the viscoelasticity of mucins. Mucins are large glycoproteins play important role in cell–cell adhesion, airways protection, Nuclear-factor kappa B signalling, epidermal growth factor receptor signalling. Eleven mucin genes (among twenty identified mucin genes) have been expressed at …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 7, Issue 3, 2017 · pp. 21–33 Read article
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Anti-Cancer Drugs-Common Types in Libya Tamoxifen: Structure and Synthesis
Abstract: This research reviews the role of anticancer organic compounds, focusing on Tamoxifen as a Selective Estrogen Receptor Modulator (SERM) and briefly comparing it to Vincristine and Vinblastine (Vinca alkaloids). At first, the review includes: classification of cancer stages, revealing symptoms of each stage. Moreover, the review gives an overview of the general classification of most of the cancer drugs, types of cancer drugs used specially in Libya, their structural differences …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 17, Issue 1, 2026 · pp. 114–123 Read article
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Antiviral and Immunomodulatory Properties of Medicinal Mushrooms with Reference to Their Role in Treating COVID-19 Infections
Abstract: Emerging, respiratory coronavirus like severe acute respiratory syndrome coronavirus (SARS-CoV-2), producing the disease COVID-19 has become the major cause of posing biological threat to mankind in today’s world. It is referred as typical pneumonia associated inflammatory infection of lungs with high morbidity and mortality rate in humans. The virus has affected more than 200 countries across the world leading to death of more that 32,000,00 people across the globe, as …
Published in Research and Reviews : A Journal of Immunology · Vol. 11, Issue 2, 2021 · pp. 23–34 Read article
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Role of Food Supplements in Premalignant Lesions: A Literature Review
Abstract: Premalignant lesions of the oral cavity are histopathological alterations in the oral epithelium linked to a higher likelihood of malignant transformation. These lesions frequently present as leukoplakia (white patches), erythroplakia (red patches), oral lichen planus, and oral submucous fibrosis. Oral cancer, categorized among head and neck malignancies, is considered the sixth most common cancer globally. While tobacco and alcohol consumption remain the primary etiological factors, increasing evidence underscores the significant …
Published in Research and Reviews: A Journal of Dentistry · Vol. 16, Issue 3, 2025 · pp. 17–26 Read article
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Arsenic as a Cause of Cancer
Abstract: Inorganic Arsenic (iAs) is a pervasive and ubiquitous environmental toxin that has created world-wide human health problems. Populations exposed to high concentrations of arsenic-contaminated drinking water suffer serious health consequences ranging from acute toxicities to development of malignancies, including alarming cancer incidence and death rates. Epidemiologic studies have shown a relationship between chronic arsenic exposure and disease of the skin, lung, urinary bladder, and conceivably liver, kidney, and prostate in …
Published in Research and Reviews: Journal of Oncology and Hematology · Vol. 5, Issue 3, 2016 · pp. 8–21 Read article