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252 articles for “ex-situ”
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Formulation Challenges in Long-acting Injectable Small Molecules: Emerging Strategies and Perspectives
Abstract: Long-acting injectable (LAI) formulations represent a transformative approach in pharmacotherapy, particularly for conditions demanding sustained drug exposure over weeks to months. Although biologics have dominated this space historically, the adaptation of LAI technology to small molecules presents a distinct and complex set of challenges rooted in physicochemical properties, manufacturing scalability, and regulatory expectations. This review systematically addresses the principal formulation barriers encountered in developing LAI small-molecule products, including aqueous solubility …
Published in Research & Reviews: A Journal of Drug Design & Discovery · Vol. 13, Issue 2, 2026 Read article
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Comparative Analysis of Data Augmentation Techniques in CNN-based Classification of Atelectasis
Abstract: This research delves into the critical issue of atelectasis, its causes, and potential complications if left untreated. Leveraging deep learning algorithms, particularly convolutional neural networks (CNN), the paper explores their application in medical image analysis, focusing on the detection of atelectasis using the “chestX-ray8” database. The study compares various data augmentation techniques for improved accuracy, showcasing the importance of augmentation in enhancing model generalization. Through meticulous experimentation and evaluation, the …
Published in Journal of Microwave Engineering and Technologies · Vol. 11, Issue 3, 2024 · pp. 1–8 Read article
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Modeling and Simulation of a Grid-Connected Solar-Wind Hybrid Renewable Energy System with Controlled Inverter
Abstract: Solar and wind energy offer eco-friendly and renewable options to conventional energy sources, holding great promise for the future. This research delves into the modeling and simulation of a grid-connected solar-wind hybrid renewable energy system employing a controlled inverter. The study examines the individual photovoltaic (PV) and wind energy conversion systems and investigates their seamless integration to create a powerful hybrid generation system. To maximize energy use, the application of …
Published in Journal of Thermal Engineering and Applications · Vol. 13, Issue 1, 2026 · pp. 22–32 Read article
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Overview AI-Driven Antenna Technologies and Privacy- Preserving Methods for Next-Generation 6G Wireless Systems
Abstract: The next generation of wireless communications, 6G, will be built on the convergence of artificial intelligence (AI) and advanced antenna systems. AI-driven antennas are poised to address the unprecedented requirements for data rate, reliability, adaptability, and ubiquity in future networks. An overview of current advancements in AI-enabled antenna systems for 6G networks is provided in this study. From traditional base station deployments to distributed, cell-free, and user-centric frameworks, it examines …
Published in Journal of Telecommunication, Switching Systems and Networks · Vol. 13, Issue 1, 2026 · pp. 28–34 Read article
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Automatic Flame Detection and Tracking
Abstract: Recent advancements in independent robotics, embedded systems, and intelligent perception have appreciably improved the capability of firefighting robots designed for early fire detection, flame localization, and suppression. A broad range of studies explores vision-based and sensor-fusion techniques designed for reliable flame discovery in complex environments. Image-processing approaches—including adaptive edge-detection, infrared/thermal imaging, color-space analysis, and profound learning—are extensively implement to enhance real-time fire gratitude, even in the presence of smoke or …
Published in International Journal of Advanced Robotics and Automation Technology · Vol. 4, Issue 1, 2026 · pp. 6–12 Read article
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Recycling of Plastic Waste Using Mini Shredder
Abstract: In the current situation, plastic use is expanding daily, leading to a significant environmental problem. Plastics can negatively affect soil organisms in a variety of ways through complex interactions. For example, it has been found that microplastics seep into the soil and change its physical makeup, which lowers the soil's ability to hold water. Particularly in India, people generate 26,000 tons of plastic waste every day which is equivalent to …
Published in Journal of Polymer & Composites · Vol. 13, Issue 3, 2025 · pp. 426–435 Read article
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Advances in Polymeric In Situ Drug Delivery and Soft Biosensors: Innovations in Biochemical Sensing and Personalized Healthcare
Abstract: Advanced healthcare and personalized medicine are undergoing a transformation thanks to in situ medication delivery systems and biochemical sensor technology. Polymeric in situ drug delivery systems form gels upon administration, releasing medications in a controlled manner and providing benefits such as ease of administration and enhanced patient compliance. Similarly, advancements in soft electronics, including flexible and stretchable biosensors, enable continuous, in situ biochemical monitoring, conforming to complex biological environments like …
Published in International Journal of Cheminformatics · Vol. 2, Issue 1, 2024 · pp. 27–32 Read article
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Role of Prey Refuge in Predator-Prey Dynamics with Nonlinear Functional Responses: A Mathematical Approach
Abstract: The Beddington-DeAnglis and Holling type II functional response with prey refuge are used in this study to propose and assess a prey-predator system. This study looks at the ecological effects of prey refuge and how it affects predator-prey relationships, highlighting how functional responses influence population dynamics. The dynamical behavior of the model has been shown, which consist the existence of positivity, boundedness, local stability, and global stability. In addition, stability …
Published in Journal of Polymer & Composites · Vol. 13, Issue 3, 2025 · pp. 523–537 Read article
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Universities in India: Study of Various Types of Universities Operational in India as of 2024 From Faculty Perspective
Abstract: The Indian university system, a legacy of British colonial rule, has witnessed significant growth post-independence. The recent implementation of the National Education Policy (NEP) 2020 further accelerates this expansion, aiming to dismantle the affiliation system and foster the growth of autonomous colleges and universities. This study explores the forms, traits, and difficulties of Indian universities, revealing their variegated environment. It looks at how various institutions respond to the rising demand …
Published in International Journal of Education Sciences · Vol. 2, Issue 1, 2025 · pp. 62–73 Read article
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Learning of Maximum Power Point Tracking Architecture with Various Algorithms for Photovoltaic Systems: A Review
Abstract: Currently, as the requirement on the Earth for ever more electricity grows, so too accordingly must demands upon renewable energy. These days, with the growth of renewable energy on all fronts, countries everywhere watch its development. Since demand for power generation goes up again, fossil fuels become less and less available, and expense is not coming down. When there is a rapidly changing irradiance, temperature, or partial shading, the output …
Published in Journal of Power Electronics and Power Systems · Vol. 16, Issue 2, 2026 Read article
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Design and Analysis of Automated Fire Detection and Suppressing System Using CNN
Abstract: Maintaining and keeping an eye on the safety of all kinds of locations and circumstances requires an alarm system that detects fire. Although the usability of many existing fire-alarm systems is widely recognized, manufacturing them may be costly. As an end result, it is miles out of reach for low-profits customers. The number one intention of this study is to create a low-fee fire control machine. The detection system, the …
Published in Journal of Experimental & Applied Mechanics · Vol. 15, Issue 2, 2024 · pp. 8–20 Read article
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Multi-Response Optimization of Turning Parameters with Vikor-Entropy Method on Machining of AA6061-TiB2 In-Situ Composites
Abstract: In the manufacturing and metal cutting industries, the quality of the surface and strength is essential in defining the surface finish; an excellent surface finish indicates excellent quality in the product. The influence of machining parameters speed, feed and depth of cut on responses like material removal rate, surface roughness and Power consumption on turning of AA6061-TiB2 composites is investigated using the VIKOR-ENTROPY method. The effects of changing parameters on …
Published in Journal of Polymer & Composites · Vol. 11, Issue 8, 2023 · pp. 256–268 Read article
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Electro Less Duplex Nickel Coating and Tribological Characterization Under Elevated Temperature
Abstract: Electroless Ni-P (EN) coatings had previously demonstrated their ability to improve the tribological properties of the underlying substantial. This is due to its high hardness, fatigue strength, and chemical resistance. Nevertheless, the EN coverings' effectiveness at high temperatures, as well as their heat resistance, have yet to be evaluated. The current work investigates the tribological properties, namely friction and wear, of EN coatings at increased temperatures (100 ºC, 200 ºC, …
Published in International Journal of Electro-Mechanics and Material Behaviour · Vol. 1, Issue 1, 2023 · pp. 12–17 Read article
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A Study to Assess the Effectiveness of Home-based Stretching Exercises on Joint Pain Among Clients with Osteoarthritis in Selected Old Age Home, Rajkot City, Gujarat
Abstract: Osteoarthritis (OA) is a commonly encountered condition in middle-aged and older individuals, marked by its slow development. Strengthening exercises targeting the quadriceps muscles, situated in the front thigh, can mitigate knee pain, and reduce disability associated with OA. The musculoskeletal system encompasses the bones of the skeleton, the joints where these bones connect, and the muscles responsible for enabling and regulating movement. The knee, the largest and most complex joint, …
Published in International Journal of Orthopedic Nursing and Practices · Vol. 1, Issue 2, 2023 · pp. 24–28 Read article
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Evolutionary History of Endemic Species of Bihar
Abstract: Bihar, a state known for its history and rich cultural heritage, is also a refuge of clearly defined species that are unique to the world and are found no place else. The present study involving the history of these species by using genetic analysis, fossil evidence, and ecological studies, investigates the situation. Through initial and secondary explanation, we can realistically infer some of them locked in so closely with their …
Published in Research & Reviews : Journal of Ecology · Vol. 14, Issue 2, 2025 · pp. 1–10 Read article
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Arthashastra as a Pedagogical Resource: Cultivating Peace Values through Ancient Statecraft
Abstract: One of the earliest Indian texts on statecraft, including the governance of a state, its economics, diplomacy, military strategy and ethics, is the Arthashastra attributed to Kautilya (Chanakaya), which was written around the 4th century BCE. Although commonly viewed through the prism of realism and the power and pragmatism, peace (shanti) is a strategic and ethical value of the text that ensures stability, prosperity (artha) and welfare (yogakshema) to the …
Published in Recent Trends in Social Studies · Vol. 3, Issue 1, 2026 · pp. 32–43 Read article
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Earthquake Detection and Monitoring System
Abstract: Earthquakes continue to be one of the major natural hazards affecting human life and infrastructure. The development of affordable monitoring systems is essential for increasing preparedness and reducing the impact of such disasters. This work presents an Earthquake Detection and Monitoring System based on a vibration sensor and Arduino controller. The system continuously observes ground movements and evaluates the detected vibration levels against a predefined threshold. Whenever unusual vibrations are …
Published in Journal of Instrumentation Technology & Innovations · Vol. 16, Issue 2, 2026 Read article
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E-Empire: Brake & Acceleration In E-Cycle
Abstract: As e-cycles continue to gain momentum as an eco-friendly and efficient mode of transportation, understanding their key mechanical and electronic systems becomes even more vital. The report delves deeply into the nuances of braking mechanisms and acceleration technologies, emphasizing their roles in enhancing both safety and performance. By comparing mechanical disc brakes with hydraulic systems, it highlights the distinct advantages of each. For instance, hydraulic brakes, known for their superior …
Published in Journal of Automobile Engineering and Applications · Vol. 11, Issue 3, 2024 Read article
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Atmospheric Boundary Layer Processes: Impacts on Weather Patterns and Climate Change
Abstract: The atmospheric boundary layer (ABL) is a vital component of the Earth's climate system, acting as the interface between the terrestrial surface and the overlying atmosphere. This layer, typically extending from the surface to a height of a few hundred meters, is characterized by strong gradients in meteorological variables such as temperature, humidity, wind speed, and atmospheric pressure. Understanding the dynamics of the ABL is essential for comprehending weather phenomena, …
Published in International Journal of Atmosphere · Vol. 1, Issue 2, 2024 · pp. 22–25 Read article
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An Experimental Investigation of Polyethylene Terephthalate Fibers in the Properties of Concrete
Abstract: In India near about every year 45 million tons of solid waste is generated. The solid waste rate is increasing of 1.5 to 2% every year. In that total solid waste, Plastics contains 12.3% waste generated in which most common are the water bottles. Now the present worldwide situation, the production of PET (Polyethylene Terephthalate) exceeds 6.9 million tons per year. So that it is necessary to reusing of PET …
Published in Journal of Polymer & Composites · Vol. 13, Issue 6, 2025 · pp. 1063–1072 Read article