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23 articles for “drug interactions”
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Assessment of exacerbation of Depression in pulmonary tuberculosis patients by using PHQ-9 scale at Tertiary Care Hospital
Abstract: Context: Depression leads to more dysfunction and stress, which could affect the patient's life condition. Tuberculosis is a leading cause of comorbidity with depression. Those suffering from tuberculosis and depression are at higher risk of bad health-seeking nature, resulting in higher morbidities, drug resistance, and mortality. The relationship is not well established. Aims: To identify multiple variables/ dependent factors affecting depression respectively in tuberculosis patients and check the medication adherence …
Published in International Journal of Pathogens · Vol. 1, Issue 2, 2024 · pp. 24–31 Read article
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A Review on: Cotard’s Syndrome
Abstract: Cotard’s Syndrome is a rare and severe mental health condition characterized by nihilistic delusions, in which individuals firmly believe that they are dead, no longer exist, or that parts of their body are decaying or missing. These beliefs are not symbolic or metaphorical but are experienced as absolute truths, making the disorder particularly distressing and difficult to manage. The syndrome is most commonly observed in association with major depressive disorder, …
Published in Recent Trends in Infectious Diseases · Vol. 3, Issue 1, 2026 · pp. 5–9 Read article
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Pharmacophore mapping, 3D QSAR, docking, and ADME prediction studies of novel Benzothiazinone derivatives
Abstract: Background Tuberculosis is a major public health concern worldwide which is caused by Mycobacterium tuberculosis. DprE1 (Decaprenyl Phosphoryl Ribose 2’- Epimerase) is the most challenging target for development of novel anti- tubercular agents because it is a small protein and located into cytoplasmic membrane. So, novel anti-TB drugs did not bound effectively with it. DprE1 catalyzes the oxidation of the 2’ hydroxyl group of DPR (Decaprenyl Phosphoryl D- Ribose) …
Published in International Journal of Antibiotics · Vol. 1, Issue 1, 2024 · pp. 59–82 Read article