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44 articles for “antiviral agent”
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Lactoferrin Nanoparticles as Therapeutic Agent for Infectious Diseases
Abstract: Lactoferrin (Lf) is a mammalian cationic iron-binding glycoprotein, present in many mammalian excretions and supporting newborn growth to food and pharmaceutical applications. It possesses antibacterial, antimicrobial, antiviral and antiparasitic activity thus, making it an important part of the host defense system. This review focusses on recent therapeutic advances of the natural bioactive protein Lf and its use as a potential treatment agent. Nanoparticles have been tremendously used for several clinical …
Published in Research and Reviews : Journal of Dairy Science and Technology · Vol. 7, Issue 3, 2018 · pp. 37–40 Read article
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Emerging Therapies in Respiratory Tract Infections: Current Advances and Future Perspectives
Abstract: The impact of respiratory tract infections (RTI) as a global public health problem continues to be high morbidity and mortality rates. The development of novel therapeutic approaches stemmed from the fact that conventional treatment strategies, antibiotics, antivirals, antifungals etc. have become increasingly ineffective because of rise of antimicrobial resistance (AMR). Next generation therapies, such as novel antimicrobial agents, host directed therapies and novel drug delivery systems have come on the …
Published in Recent Trends in Infectious Diseases · Vol. 2, Issue 2, 2025 · pp. 17–25 Read article
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Oxadiazole Derivatives Recent Progress in Synthesis and Bioactivity
Abstract: Over the past few decades, significant advancements have been made in the development of heterocyclic derivatives, leading to the production of numerous novel agents, both synthetic and natural in origin. Because of its numerous biological properties, including antibacterial, antiviral, and antifungal properties, thiazole is a special five-membered heterocyclic motif among heterocyclic compounds. It is utilized as a fundamental building block in many pharmaceutically significant compounds. To the best of our …
Published in Journal of Modern Chemistry & Chemical Technology · Vol. 15, Issue 1, 2024 · pp. 62–67 Read article
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Phytotherapeutic Potential of Melaleuca: An Integrative Review of Phytochemistry and Antimicrobial, Antifungal, Antioxidant, and Antiviral Mechanisms
Abstract: Melaleuca alternifolia and other species of the Melaleuca genus stand out for the broad spectrum of pharmacological properties attributed to their bioactive compounds, such as monoterpenes, sesquiterpenes, flavonoids, and polyphenols. This study aimed to critically review and analyze scientific evidence produced between 2005 and 2025 regarding the antimicrobial, antifungal, antioxidant, and antiviral activities of Melaleuca, correlating its phytochemistry with molecular mechanisms of action. For this purpose, an integrative literature review …
Published in Research & Reviews : Journal of Herbal Science · Vol. 15, Issue 2, 2026 Read article
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COVID-19: Nija or Agantuj Roga, Ayurvedic Perspective
Abstract: which is explained under name Janapadodhwamsa or Maraka, It is explained in detail as an independent chapter in various classical texts. As per description Ayurvedic literature described their mechanism of Aetiology (Nidana), various factors affecting severity and actions complicating illnesses along with their management and preventive method. In this article,An attempt is made to describe it as per our classical science, which assert the superiority of host susceptibility (Nija) over …
Published in Research and Reviews: A Journal of Health Professions · Vol. 13, Issue 4, 2023 · pp. 19–23 Read article
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COVID-19: Nija or Agantuj Roga, Ayurvedic Perspective
Abstract: Epidemics have not been new concept neither to universe nor for India. Ayurveda, which is most ancient, documented science of health care system, has documented concept of epidemics thousand years ago and which is explained under name Janapadodhwamsa or Maraka. It is explained in detail as an independent chapter in various classical texts. As per description, Ayurvedic literature described their mechanism of Aetiology (Nidana), various factors affecting severity and actions …
Published in Journal of AYUSH: Ayurveda, Yoga, Unani, Siddha and Homeopathy · Vol. 11, Issue 1, 2022 · pp. 18–22 Read article
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Cinnamon Extract and Cinnamaldehyde Inhibit the Replication of T2 Bacteriophage in E. coli: Potential for Use in Antiviral and Anticancer Therapy
Abstract: An extract of cinnamon inhibits the growth of bacteria, viruses and cancer cells. At concentrations of 1, 2, 4, and 8 ml per 100 ml of Luria-Bertani broth, cinnamon extract had virtually no effect on the growth of E. coli. At the same concentrations, however, the yield of T2 bacteriophage was 98, 76, 64.5, and 61.8% of the control. Addition of cinnamon extract 37 min before infection produced a yield …
Published in Research and Reviews : A Journal of Biotechnology · Vol. 9, Issue 3, 2019 · pp. 8–17 Read article
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Nigella Sativa Can Act as a Protective Agent to Fight Against Covid-19: An Update
Abstract: The severe acute respiratory syndrome coronavirus 2 (SARS CoV-2) causes Coronavirus Disease-19 (COVID-19), which began in Wuhan, Hubei Province, China and has since spread around the world. There are currently no effective antiviral medicines authorised for these coronavirus strains. Chloroquine, hydroxychloroquine, lopinavir/ritonavir, ribavirin, remdesivir, favipiravir, umifenovir, interferon-α, interferon-β, and other drugs are used to treat COVID19. There is no specific, effective, or proven conventional treatment to treat COVID-19 patients. As …
Published in Research & Reviews: A Journal of Pharmacognosy · Vol. 9, Issue 1, 2022 · pp. 13–18 Read article
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QSAR Modeling of a Novel Series of Methoxylated Chalcones as Antioxidant Agents Against Gram-Positive Bacteria Staphylococcus aureus
Abstract: Background: Chalcones are aromatic ketones belonging to the flavonoid family. They are plant-based compounds and are widely found in nature. For centuries, these bioactive molecules have been utilized in various traditional medicines for the treatment of several ailments. Chalcones have antibacterial, antiviral, antimalarial, antifungal, antioxidant, and antileishmanial properties. They are also used to treat inflammation and cancer. Chalcones act as angiogenesis inhibitors, an important factor in cancer progression and metastasis. …
Published in International Journal of Biochemistry and Biomolecule Research · Vol. 3, Issue 1, 2025 · pp. 28–34 Read article
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Detection of Active Compounds in Ulothrix sp. Algae
Abstract: The study included the identification of some active chemical compounds from blue-green algae Ulothrix and the production of many active compounds using algae extract. Algae are a talented cause of defiant corpulence mediators, as plump positions are an international hazard to human wellbeing. It is also linked to metabolic syndrome, type 2 diabetes, heart disease and blood vessels, anti-obesity agents from algae are represented by four main compounds with (Phlorotannins, …
Published in Research and Reviews : A Journal of Biotechnology · Vol. 14, Issue 3, 2024 · pp. 39–43 Read article
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Exploring the Botanical and Pharmacological Significance of Aristolochia rotunda Linn (Zarawand Mudahraj): Traditional Uses, Habitat, and Bioactive Potential
Abstract: The plant Aristolochia rotunada Linn (Zarawand Mudahraj) is a member of the Aristolochiaceae family. Its rhizomes are the most valuable portion utilised in the pharmaceutical industry, mostly because of their abundance in bioactive compounds. The medicinal plant Aristolochia rotunda Linn exhibits a spectrum of pharmacological activities essential for combating hyper-uricaemia-induced inflammation. Its anti-inflammatory effects are mediated by inhibiting TNF-α, IL-1β, IL-8, and NF-κB p65 protein expression, crucial in synovial tissue. …
Published in Research & Reviews : Journal of Herbal Science · Vol. 13, Issue 2, 2024 · pp. 33–39 Read article
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Molecular Docking-Based Analysis of Rauvolfia serpentina Alkaloids Targeting HPV E1 and L1 Proteins for Antiviral Therapeutic Potential
Abstract: Human papillomavirus (HPV) is a major cause of cervical cancer and other epithelial cancers. E1 and L1 proteins are crucial to the virus's lifespan. E1 is a viral helicase that is needed for HPV DNA replication, and L1 is the main structural capsid protein that builds the virion and infects target cells. Going after these proteins is a good way to stop viruses from spreading. In this case, Rauvolfia serpentina, …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 17, Issue 1, 2026 · pp. 100–113 Read article
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A Comparative Study of Cost and Effectiveness of Antiviral Disinfectants for Various Societal Needs under COVID-19 Pandemic Situation
Abstract: The COVID-19 pandemic has already infected people in 188 countries across the world. No known antiviral drugs have been effective against this virus till now. Proper practice of hygiene, sanitization and social distancing is the only effective precaution against this novel coronavirus. Disinfection is not only required for hospitals and health centers but also for households, apartments, offices, educational institutes and other buildings of public interests not related to health …
Published in Research and Reviews : A Journal of Medical Science and Technology · Vol. 9, Issue 3, 2020 · pp. 1–18 Read article
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A Critical Review Study of Prakriti Vighata Chikitsa in Management of Chronic Infection of Alimentary Tract Annavaha Srotas with Special Reference to Role of Sudarshana Churna in Management of Viral B Hepatitis
Abstract: AbstractKrimi refers to all types of infectious agents – microscopic or macroscopic. These agents produce diseases in the body. Ayurvedic scholars described three treatment modalities for them. Prakriti Vighata is one of them and is a unique approach of Ayurveda for the treatment of chronic infections. Prakrti Vighata management refers to changing the histopathological atmosphere in such a manner that is not favorable to the growth and development of Krimi. …
Published in Journal of AYUSH: Ayurveda, Yoga, Unani, Siddha and Homeopathy · Vol. 2, Issue 3, 2013 · pp. 1–5 Read article
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In Silico Identification of Therapeutic Agents for Dengue Virus by Molecular Docking
Abstract: The dengue virus causes serious health issues and a loss of quality of life. Dengue poses a yearly threat to half of the world’s population. The drugs that are based on allopathy are expensive and also exhibit toxic effects on tissues and biological activities. It is also generally accepted that most pharmacologically active drugs, including those derived from medicinal plants, are isolated from natural sources. The present study is directed …
Published in Research & Reviews: A Journal of Drug Design & Discovery · Vol. 13, Issue 2, 2026 · pp. 01–14 Read article
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In Silico Assessment of Demethoxycurcumin: Molecular Docking and Computational Insights into its various therapeutic Potential
Abstract: Natural compounds are increasingly explored for their therapeutic potential in medical research. Here, we focused on demethoxycurcumin (DMC), a polyphenolic bioactive compound extracted from Curcuma longa, commonly found in turmeric. DMC, with a chemical formula of C20H18O5 and a molecular weight of 340 g/mol, possesses two aromatic ring systems, each featuring a β-diketone moiety connected by a seven-carbon chain. This unique structure allows DMC to engage in tautomerism, which is …
Published in Research & Reviews: A Journal of Drug Design & Discovery · Vol. 11, Issue 1, 2024 · pp. 9–15 Read article
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Ivermectin: Its Therapeutic Efficacy in the Treatment of COVID-19
Abstract: Over past 35 years the most commonly used anti-helminthic drug is ivermectin. It has showed good impact in treating the parasitic infections. The drug provides an evidence of immune modulatory and anti-inflammatory actions in vitro animal model. Ivermectin belongs to the class of ivermectin and most widely used as an anti-parasitic agent. It is also used in the treatment of internal nematode infections like onchocerciasis, filariasis, and strongloidiasis. For the …
Published in Research and Reviews: A Journal of Microbiology and Virology · Vol. 11, Issue 3, 2021 · pp. 1–5 Read article
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Aquatic Ecosystems: A Review on Prospecting of Anticancer Molecules from Fungi & Other Microbes
Abstract: Marine biota; namely, actinomycetes, bacteria, fungi, microalgae, green algae, oceanic weeds, mangroves, and other extremophiles constitute about 90% of the oceanic biomass. The organisms are taxonomically diverse, biologically productive/active, and biochemically unique. These unique biochemiques may act as a great source for the discovery of new bioactive molecules, including anticancer drugs. The marines produce medicinally potent biochemicals; namely, sulfated saccharides, polyphenols, and, sterols. Only a few of these alkaloids have …
Published in International Journal of Fungi · Vol. 1, Issue 2, 2024 · pp. 1–22 Read article
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Computer-aided Drug Design Method for Anti-hepatitis C Drug Design
Abstract: Hepatitis C is a disease caused by the hepatitis C virus and can cause serious liver damage. There is currently no vaccine for this disease and the number of infections continues to increase worldwide. Currently used antiviral drugs are interferon alfa-2a and ribavirin, but about half of patients do not respond to therapy. Therefore, new drugs that protect against hepatitis C need to be investigated. Computational drug methods have been …
Published in Research and Reviews : A Journal of Immunology · Vol. 14, Issue 2, 2024 · pp. 1–8 Read article
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Induction of G1 Phase Cell Cycle Arrest and Apoptosis in Breast Cancer MCF-7 Cells by Sulphonamide Derivative CID-6861424
Abstract: Breast cancer is most frequently detected and leading cause of cancer death in women worldwide. 80% of the breast cancer are estrogen receptor positive and the presently available drugs are ineffective either due to intrinsic resistance or due to acquired resistance. Sulfonamide compounds are a class of compounds showing activities like, antibacterial, antiviral including antitumor. In the present study we have investigated the anti-cancerous activity of sulfonamide derivative CID-6861424 on …
Published in Research and Reviews: A Journal of Toxicology · Vol. 9, Issue 2, 2019 · pp. 1–17 Read article