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465 articles for “Toxic effects”
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A brief survey on Alternative and Complementary Medicine with special reference to safety, toxins and toxicological concerns
Abstract: Alternative and Complementary Medicine (ACM) is a wide range of healthcare practices that may be used within or alongside conventional medicine, and many of these practices are rapidly becoming accepted and integrated into the modern healthcare system. In addition to traditional medicine systems (e.g. Ayurveda, Unani Medicine, Traditional Chinese Medicine, and Homeopathy), ACM includes practices that utilize natural remedies including herbal medicine, phytotherapy, naturopathy, acupuncture, yoga, and meditation. While these …
Published in International Journal of Toxins and Toxics · Vol. 3, Issue 1, 2026 · pp. 30–45 Read article
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Ozone Therapy: A New Era Paradigm
Abstract: There are evidences which suggest that ozone does have various therapeutic effects that range from disinfection of pathogens, anticancer properties, and treatment of back ailments. Due to the controlled and moderate oxidative stress produced by the reactions of ozone with several biological components, the therapeutic efficacy of ozone therapy is seen. Strength of the oxidative stress may show the line between effectiveness and toxic effect of ozone therapy. This observation …
Published in Research and Reviews : A Journal of Immunology · Vol. 8, Issue 1, 2018 · pp. 22–30 Read article
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Effects of multiglutine during cancer chemotherapy on gastrointestinal toxicity and liver dysfunction
Abstract: Introduction: Cancer chemotherapy causes severe side effects in almost patients by inhibiting various systems including the hematopoietic, gastrointestinal and nervous systems. Recently, glutamine has been considered to improve the side effects of cancer chemotherapy. Calcium and magnesium also have positive effects in cancer patients. In this study, we evaluated effects of multiglutine, which consists of glutamic acid and metal ions such as calcium, magnesium, on gastrointestinal toxicity and liver dysfunction …
Published in Research and Reviews: A Journal of Medicine · Vol. 13, Issue 3, 2023 · pp. 13–18 Read article
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In Silico Study of Histone Deacetylase Inhibitor as Anticancer Agents
Abstract: The clinical selective histone deacetylase inhibitor vorinostat is most commonly used for the treatment of lymphoma and solid tumor and has been preventing lives worldwide. Vorinostat is used in both treatment and prevention of lymphoma and other tumors. Based on these for current study some vorinostat derivatives with thiadiazole moiety containing derivatives have been designed for in silico study. For present work, the already selected study was against histone human …
Published in Research & Reviews: A Journal of Drug Design & Discovery · Vol. 6, Issue 2, 2019 · pp. 6–23 Read article
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Histological and Functional Effect of Melatonin on Reproductive System
Abstract: Many experimental studies reported that melatonin has shown to induce reproductive toxicity. The purpose of this review is to discuss the evidence regarding the toxic effect of melatonin on the reproductive system and its possible mechanism of toxicity. Literature included in thisreview showed that an extrinsic dose of melatonin inducespharmaceutical, biochemical and physiological effects on the mammalian reproductive function. Empirical and histological examination of melatonin exposure on reproductive function has …
Published in Research and Reviews : A Journal of Medical Science and Technology · Vol. 9, Issue 1, 2020 · pp. 16–23 Read article
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Cadmium Toxicity: Oxidative Stress and Organ Dysfunction
Abstract: Due to continued anthropogenic mobilization, cadmium accumulation in the environment causes various health problems because of its diverse toxic effects, extremely lingering biological half life (20–30 years), low rate of excretion from the body and storage predominantly in soft tissue primarily liver and kidney. Cadmium is known to have numerous noxious effects, including nephrotoxicity, hepatoxicity, osteoporosis, cardiovascular toxicity, lung toxicity, and reproductive toxicity. The biologically significant ionic form of cadmium, …
Published in Research and Reviews: A Journal of Toxicology · Vol. 4, Issue 2, 2014 · pp. 14–31 Read article
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Prospective Evaluation of the Optimal Concentration and Effect of Epinephrine as an Adjuvant to Local Anesthetics for Prolonging Block Duration and Reducing Systemic Toxicity in Outpatient Surgery
Abstract: Purpose: To evaluate the optimal concentration and effect of epinephrine as an adjuvant to local anesthetics for prolonging block duration and reducing systemic toxicity in outpatient surgery. Methods: The study involved a randomized double-blind clinical trial on 80 adult patients awaiting day-care extremity surgery. The patients were randomly assigned to two groups of equal size. One group, Group E, was given the local anesthetic agent along with epinephrine as an …
Published in Research and Reviews: A Journal of Toxicology · Vol. 16, Issue 1, 2026 · pp. 64–69 Read article
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Assessment of Hepatic Damage in Labeo rohita (Hamilton, 1822) Exposed to Azo dye C. I. Direct Green 6
Abstract: Textile industries are one of the major backbones of Indian economy. They are the major reason for contamination of water bodies and their toxicity to ecosystem is an alarming environmental issue. The present study was designed to evaluate the hepatotoxic effects of C.I. Direct Green 6 (DG 6), a commercially used textile azo dye on Labeo rohita fingerlings. For this, L. rohita fingerlings were exposed to three sublethal concentrations (2.5, …
Published in Research and Reviews : Journal of Veterinary Science and Technology · pp. 1–8 Read article
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Case Study on Snake Bite
Abstract: Snakebites are a major public health concern in India, with the World Health Organization (WHO) estimating approximately 5 million cases annually. Out of these, around 2.7 million involve envenomation, where venom is injected through the snake's bite. These venomous bites pose significant medical emergencies and can lead to severe complications, including permanent physical impairments if not treated promptly. Immediate medical intervention is crucial to mitigating the adverse effects of snakebites. …
Published in Research and Reviews : Journal of Surgery · Vol. 13, Issue 2, 2024 · pp. 21–25 Read article
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Toxicology and Its Branches: A Brief Review
Abstract: Toxicology is called the science of poisons or can be defined as any substance, whose exposure can cause harm to any living body or to the environment. It can also be defined as the study of adverse effects of different chemical, biological or physical agents on living organisms and the ecosystems, including the prevention & enhancement of such adverse effects. It is concerned with all aspects of different poisons and …
Published in Research and Reviews: A Journal of Toxicology · Vol. 11, Issue 2, 2024 · pp. 27–45 Read article
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Phytochemistry and Antimicrobial Potential of Apang (Achyranthes aspera L.): An Update Review
Abstract: Normal 0 false false false EN-US X-NONE X-NONE With the increase of synthetic antibiotic resistance and severe side effects, the pharmaceutical industry is interested in finding new drugs from natural sources with fewer or no side-effects. The present review deals with the phytochemical and antimicrobial aspects of Achyranthes aspera- a commonly used folk medicinal plant in Bangladesh and other tropical countries. Different parts of this plant (leaf, root, stem and …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 3, Issue 2, 2012 · pp. 1–8 Read article
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Effects of Sub Chronic Dermal Exposure of Gasoline Blended with Varying Concentration of Benzene on Hepatic Mixed Function Oxidases in Rats
Abstract: Interaction of chemicals in a mixture, their biotransformation and adverse impact, if any, on environment and workroom atmosphere needs to be evaluated to identify the nature of potential toxic effects elicited by constituent chemical(s) in a mixture. The nature of chemical interaction(s) through which an individual chemical in a mixture undergoes metabolism and/or biotransformation in the target tissue could be helpful in evaluation of its toxic potential. Gasoline is a …
Published in Research and Reviews: A Journal of Toxicology · Vol. 3, Issue 1, 2013 · pp. 1–5 Read article
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Determination and Study of The Effect of High Concentrations from Heavy Metals in Environmental Samples
Abstract: This study focused on determining the concentrations of heavy metal ions to assess the environmental pollution levels of five T stations. Based on this, five samples were collected from different environments in Najaf Governorate, and the levels of heavy metal pollution were compared with the permissible values set by the World Health Organization. The research study concerned measurements of the increase and decrease in the concentration of elements and minerals …
Published in Journal of Modern Chemistry & Chemical Technology · Vol. 16, Issue 2, 2025 · pp. 77–84 Read article
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Evaluation of Metal Pollution in Wetlands Using Fish as an Indicator
Abstract: The current study has attempted to document the heavy metal pollution in wetlands using fish as an indicator. Heavy metals are one of the most toxic, persistent and widespread groups of contaminants in aquatic systems. Their effects may often occur and remain unrecognized at the individual level but slowly, over a period of time, show up at a population level. Over a few decades globally there has been growing interest …
Published in Research and Reviews: A Journal of Toxicology · Vol. 1, Issue 1-3, 2011 · pp. 28–38 Read article
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Hematological and Biochemical Changes in the Freshwater Fish, Pseudetroplus Maculatus Exposed to Sublethal Concentrations of Chlorpyrifos
Abstract: Sublethal effects of chlorpyrifos on hematological and biochemical parameters were assessed in the freshwater fish, Pseudetroplus maculatus. Fish were exposed to chlorpyrifos at two sublethal concentrations, 0.661 µg/L (one-tenth of LC50—96 h) and 1.32 µg/L (one-fifth of LC50—96 h), for 15 and 30 days maintaining the control group. Blood collected from the control and treated groups were used for analyzing the hematological and biochemical parameters. Chlorpyrifos exposure significantly (P<.05) decreased …
Published in Research and Reviews : A Journal of Life Sciences · Vol. 8, Issue 3, 2018 · pp. 108–116 Read article
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Sub-acute Toxicity of β-cyfluthrin in Hepatic Tissue and its Amelioration through Punica granatum in Swiss albino mice
Abstract: β-cyfluthrin, member of synthetic pyrethroid pesticide Type II is broadly used multipurpose insecticide. Widespread and indiscriminate use of β-cyfluthrin leads to environmental contamination and toxicity towards nontarget mammalian systems. The present study was undertaken to examine toxic manifestation of β-cyfluthrin in hepatic tissue of Swiss albino mice and also evaluate possible mitigative potential of pomegranate juice (PJ) in combating pesticide induced hepato-toxicity. Animals were divided into five groups namely, control, …
Published in Research and Reviews: A Journal of Toxicology · Vol. 10, Issue 3, 2020 · pp. 41–52 Read article
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Managing Chronic Kidney Disease using Plant Based Therapies indepth review
Abstract: Chronic kidney disease (CKD) is a debilitating condition with a constantly increasing incidence associated with global financial and social burden on health care systems. The last stage of CKD is kidney failure which if left untreated with kidney replacement therapies is significantly life threatening. Modern treatment schedules of CKD focus on delaying the disease progression by using angiotensin-converting enzyme inhibitors, angiotensin II receptor blockers and calcium channel blockers. The three …
Published in Research & Reviews: A Journal of Pharmacognosy · Vol. 10, Issue 2, 2023 · pp. 17–43 Read article
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Comparison of Total Protein Content in the Muscles of Catla catla on Exposure to Ag and ZnO Nanoparticles and their Metal Ions
Abstract: Growing applications of nanotechnology necessitates understanding of nanotoxicity. The toxicity of nanoparticles has gained special attraction amongst various toxicological studies, but restricted data are available on its toxic effects on aquatic organisms. An attempt has been made in present investigation to determine toxicity of NPs of Ag and ZnO and their metal ions to major carp catla. Protein content in muscle tissues of the fingerlings varied with concentration of the …
Published in Research and Reviews : A Journal of Life Sciences · Vol. 7, Issue 3, 2017 · pp. 1–6 Read article
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Toxicological Evaluation Of Two Nigerian Refinery Effluents Using Natural Biomonitors
Abstract: Abstract The present study aimed to evaluate the toxic effects of two Nigerian refineries’ effluents using natural bio-monitors. Standard physicochemical analysis, toxi-chromo test using mutant E. coli and sub-chronic animal toxicity testing with emphasis on tissue heavy metal accumulation, biochemical parameters and histopathology, were adopted during the study. The physicochemical results revealed that the two effluent samples are highly polluted although PH sample was more polluted than the Warri sample. …
Published in Research and Reviews: A Journal of Toxicology · Vol. 10, Issue 2, 2020 · pp. 22–31 Read article
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The New Dimension of Cancer: It is Not a Disease but a Deficiency of Vitamin B17
Abstract: Most commonly used an alternative drug in the treatment of tumor in the last 40 years is Amygdalin. Treatment based on the use of Vitamin B-17, proteolytic pancreatic enzymes, immunostimulants, vitamin and mineral supplements for cancer is a metabolic therapy which is nontoxic. National Cancer Institute is unsuccessful to prove that Laetrile is ineffective and toxic during their studies by clinical trials in 1981. Today, position on the "front lines" …
Published in Research and Reviews: Journal of Oncology and Hematology · Vol. 7, Issue 3, 2018 · pp. 34–36 Read article