Search
40 articles for “Review Blood cancer”
-
Renin-Angiotensin System as a Therapeutic Target for Colorectal Cancer Liver Metastasis
Abstract: Classically, renin-angiotensin system (RAS), for a long time, has been perceived as the main regulator of cardiovascular homeostasis, due to its effect on blood vessels contraction or cardiac hypertrophy and is known to maintain blood pressure and body fluids. Hence, its pharmacological regulation is mainly associated with the management of hypertension. Currently, it was found that the RAS is involved in a broad range of physiological processes and diseases. RAS …
Published in Research and Reviews: Journal of Oncology and Hematology · Vol. 7, Issue 2, 2018 · pp. 1–14 Read article
-
A REVIEW: P-GLYCOPROTEIN AND ITS ROLE IN CANCER
Abstract: Abstract The review is done on how P-glycoprotein recognizes various substrates and plays a key role in cancer. Chemotherapy is used for cancer treatment but multidrug resistance of cancerous cell is the major obstacle in therapy and also an important aspect which causes failure in the treatment by effluxion of a xenobiotic on the plasma membrane. In humans, P-glycoprotein is important transmembrane transporter. It is located on the apical surface …
Published in Trends in Drug Delivery · Vol. 7, Issue 2, 2020 · pp. 26–34 Read article
-
Arsenic as a Cause of Cancer
Abstract: Inorganic Arsenic (iAs) is a pervasive and ubiquitous environmental toxin that has created world-wide human health problems. Populations exposed to high concentrations of arsenic-contaminated drinking water suffer serious health consequences ranging from acute toxicities to development of malignancies, including alarming cancer incidence and death rates. Epidemiologic studies have shown a relationship between chronic arsenic exposure and disease of the skin, lung, urinary bladder, and conceivably liver, kidney, and prostate in …
Published in Research and Reviews: Journal of Oncology and Hematology · Vol. 5, Issue 3, 2016 · pp. 8–21 Read article
-
A Review on Psidium Guajava
Abstract: Psidium guajava is an evergreen shrub belongs to Myrtaceae family and commonly known as guava. It contains phenolic compounds and acts as anti-oxidant properties as well as immunostimulant. It has a higher number of vitamins and minerals. Every part of this plant contains various phytochemicals like quercetin, rutin, kaempferol, gallic acid, epicatechin, ursolic acid, glucosides, guavanoic acid, guava coumaric acid, saponins, terpenoids are present. It shows various pharmacological activities like …
Published in Research and Reviews : Journal of Crop science and Technology · Vol. 10, Issue 3, 2021 · pp. 9–14 Read article
-
Hematopoietic Stem Cells: Sources and Therapeutic Potential for Autoimmune Diseases and Cancer
Abstract: Hematopoietic stem cells (HSCs) are a group of multipotent adult stem cells that are responsible for lifelong production of all types of functional blood cells comprising myeloid (monocytes, macrophages, granulocytes), megakaryocytes/platelets, red blood cells (erythrocyte), T-cells, B-cells, natural killer (NK) cells, mast cells and dendritic cells (DCs). HSCs have the capacity for self-renewal and differentiation into various tissues. These remarkable properties of HSCs make them an ideal tool for tissue …
Published in Research and Reviews: Journal of Oncology and Hematology · Vol. 1, Issue 3, 2012 · pp. 6–14 Read article
-
Treatment of Severe Iron Deficiency Anemia with the Traditional Koryo Medicine—Ginseng Anticancer Composite Drug (GACCD)
Abstract: In contrast to many medical conditions whose discovery carries a specific date often associated with a particular investigator, iron deficiency is an ancient disorder that stretches to the dawn of human history. In recent years, Iron deficiency anemia (IDA) is a disease that has reached epidemic proportions affecting countries worldwide, when it commonly begins from denutrition. Iron deficiency produces microcytic hypochromic red cells and substantially depresses both the mean corpuscular …
Published in Research and Reviews: Journal of Oncology and Hematology · Vol. 8, Issue 3, 2019 · pp. 13–17 Read article
-
Review on Histological and Functional Effect of Alcohol on Liver and Kidney
Abstract: Alcohol consumption represents the third largest risk factor for disease burden in most countries of the world. The purpose of this review is to give a comprehensive report of the existing data on the potential adverse effects of alcohol on liver and kidney toxicity. We used 82 different published materials for the compilation of this review article. The Google search engine was used for accessing published materials from databases like …
Published in Research and Reviews : A Journal of Medical Science and Technology · Vol. 7, Issue 2, 2018 · pp. 49–62 Read article
-
Glutathione: Postoperative Study in Breast Carcinoma
Abstract: Breast cancer represents a significant problem in the world. Glutathione a tripeptide is found in all mammalian tissues. Thus any change in its synthesis or utilization can profoundly influence the redox status of cells. In this study blood sample was collected from 60 FNAC confirmed breast cancer patients (preoperative and postoperative three months) and 30 normal healthy controls for the estimation of glutathione. There was significant increase in glutathione in …
Published in Research and Reviews: Journal of Oncology and Hematology · Vol. 7, Issue 1, 2018 · pp. 3–6 Read article
-
Nitric Oxide—An Important Biomolecule in Breast Carcinoma
Abstract: Breast cancer represents significant problem of the world. Reactive nitrogen species of which nitric oxide (NO) is important constituent is a free radical gas which is synthesized by nitric oxide synthase (NOS).NO inhibits DNA synthesis and can damage DNA directly by deamination. In this study, NO level was studied in normal, pre- and postoperative cases of breast carcinoma. For this blood samples from 60 breast carcinoma cases were taken along …
Published in Research and Reviews: A Journal of Health Professions · Vol. 8, Issue 3, 2018 · pp. 55–59 Read article
-
Glutathione peroxidase (GPx) in Breast Carcinoma
Abstract: Cancer is one of the significant problem from health perspective, every year many females are diagnosed with breast cancer out of which many die because of this disease worldwide. Oxidative stress in human body is a result of imbalance between free radical production and antioxidant defense which may result in carcinogenesis. Primary defense Primary defenses rely on the direct scavenging and inactivation of the reactive oxygen species (ROS) which includes …
Published in Research and Reviews : A Journal of Life Sciences · Vol. 8, Issue 3, 2018 · pp. 1–5 Read article
-
FERMENTED FOODS: FUNCTIONAL AND REGULATORY INSIGHTS
Abstract: Traditional fermented edible products have been in the food industry since ancient times. Today, the fermentation process has become most common in the health food industry. Due to the microorganisms present in fermented food products, the health benefits have been helpful in many ways. Fermentation helps in enhancing gut health, blood sugar, blood pressure, and brain health. These food products also play a major role in lowering cancer risk and …
Published in Research and Reviews : A Journal of Biotechnology · Vol. 15, Issue 3, 2025 · pp. 1–10 Read article
-
Review on Dioscorea alata and its Pharmacological application
Abstract: Dioscorea alata, also known as water yam, is an important crop found worldwide. About 600 different species have been reported worldwide. Many nations, including South America, Africa, Australia, and the southern United States, cultivate D. alata. D. Alata is a member of the Discordance family and has been demonstrated to possess anti-inflammatory, anti-apoptotic, and antioxidant qualities. Dioscorea's metabolites include phenolic chemicals, which reduce sugars, flavonoids, glycosides, saponins, alkaloids, anthraquinones, proteins, …
Published in Research & Reviews: A Journal of Pharmacognosy · Vol. 12, Issue 2, 2025 · pp. 80–86 Read article
-
History, Processing, Types and Health Benefits of Indian Yogurt
Abstract: Yogurt is a food which is nutrient rich and it is produced after the milk bacterial fermentation. Yogurt should have 3.25% milk fat and 8.25% milk solids non fat and the titrable acidity of at least 0.9%, which is expressed as lactic acid. Before adding bulky flavoring additives, the USDA yogurt criteria specify that the yogurt must satisfy the composition requirements of milk fat and MSNF. The data used in …
Published in Research and Reviews : Journal of Dairy Science and Technology · Vol. 13, Issue 1, 2024 · pp. 1–6 Read article
-
Clinical Significance of Immune Cells and T-cell Subsets in Lung Cancer
Abstract: Objectives: The aim of the study was to determine the clinical usefulness of pretreatment hematological parameters including neutrophils, lymphocytes, monocytes and immune T-cell subsets as well as calculated coefficients such as neutrophils-to-lymphocytes ratio(NLR),monocytes-to-lymphocytes ratio(MLR) and platelets-to-lymphocyte ratio(PLR)in patients with lung cancer. Materials and Methods: A total of 102 patients with lung cancer were prospectively analyzed. T-cell subsets were assessed by flow cytometry method. Peripheral blood was collected from 25 healthy …
Published in Research and Reviews : A Journal of Immunology · Vol. 9, Issue 2, 2019 · pp. 14–29 Read article
-
CBD: Wonder Drug of the Future
Abstract: The traditional “wonder drug” in pharmacology is aspirin, well known for its properties of pain control, lowering elevated body temperature, fighting inflammation, and decreasing blood coagulation. Aspirin, as a non-steroidal anti-inflammatory drug (NSAID) is a preventative drug as well as a therapeutic one. The Framingham heart study has concluded that a low dose aspirin regimen (81 mg/day) will help prevent cardiovascular disease and stroke. On the other hand, CBD (cannabidiol) …
Published in Research and Reviews: A Journal of Neuroscience · Vol. 7, Issue 1, 2017 · pp. 1–5 Read article
-
Obesity (Siman-E-Mufrat) in Greeco-Arabic Perspective: A Review
Abstract: Tibb-e-Unani has been rendering services to the mankind for thousands of years. This healing art is one of the oldest and well organized systems of medicine. The Greeks were the first to recognize Siman-e-mufrat (obesity) as a medical disorder. It is evident that Buqrat (460–377 BC) was first who described obesity (siman-e-mufrat) in his famous book Fusool-e-Buqrat. Buqrat understood that siman-e-mufrat leads to infertility and early death. He was also …
Published in Research & Reviews : A Journal of Unani, Siddha and Homeopathy · Vol. 2, Issue 1, 2015 · pp. 10–16 Read article
-
Review on Drug Nanoparticles: Special Emphasis on Herbal Nanoparticals
Abstract: Nanoparticles have greater research horizon and smaller size ranging from 1 to 1000 nm. This is very small as compared to other particles. As their size is extremely small, so ultimately their route of administration and reaching to site of action becomes more convenient. These nano-scale particles can easily pass out the cell membrane such as blood brain-barriers. Nanoparticles are synthesized from various metals, polymers, microbes and even from plant …
Published in Research & Reviews: A Journal of Drug Formulation, Development and Production · Vol. 7, Issue 3, 2020 · pp. 48–58 Read article
-
Exploring the Therapeutic Potential of Phytohormones: Bridging Plant Immunity and Human Health
Abstract: This review highlights the multifaceted roles of phytohormones, including salicylic acid, abscisic acid, cytokinins, and brassinosteroids, emphasizing their contributions to plant immunity and potential therapeutic applications in human health. Phytohormones are critical regulators of plant growth, development, and defense, functioning as signaling molecules that activate and coordinate plant responses to biotic and abiotic stresses. Salicylic acid, in particular, is instrumental in systemic acquired resistance (SAR), a defense mechanism that strengthens …
Published in International Journal of Trends in Horticulture · Vol. 1, Issue 2, 2024 · pp. 20–23 Read article
-
To Develop Self-instructional Module on ‘Umbilical Cord Stem Cell Collection, Preservation and Utilization’ and Evaluate its Effectiveness on Improving the Knowledge of Operational Level Nurses
Abstract: Umbilical cord stem cell based regenerative and cellular medicine has now become a fascination for all. The umbilical cord blood, donated by mothers after the birth of newborn, has become an accepted source of hematopoietic stem cells for bone marrow reconstitution. They play an important role in the treatment of blood and immune system related genetic diseases, cancers, and blood disorders. This study is aimed to assess the knowledge of …
Published in Research and Reviews: Journal of Oncology and Hematology · Vol. 9, Issue 3, 2020 · pp. 10–22 Read article
-
Attenuation of Doxorubicin-induced Hepato- and Nephrotoxicity by Proanthocyanidins from Myrica nagi Bark in Wistar Rats
Abstract: Due to dose-related toxic effects, doxorubicin, a very potent and often used anti-cancer medication, is largely limited. The current research investigated the protective impact of Myrica nagi bark (PMN)-isolated proanthocyanidins on hepato-induced doxorubicin and nephrotoxicity in Wistar rats. The animals were subdivided into six classes of five rats each. Group I got PMN (200 mg/kg, p.o.) for 21 days, Group II received Doxorubicin (DXR) (60 mg/kg, i.p.) once, 48 h …
Published in Research and Reviews: A Journal of Toxicology · Vol. 10, Issue 3, 2020 · pp. 19–28 Read article