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36 articles for “Parkinson’s Disease”
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A Comprehensive Review on Neturaceuticals in Alzheimer's and Neurodegenerative Disease an Cognitive Enhancement
Abstract: Neurodegenerative diseases, including Alzheimers disease (AD), Parkinsons disease (PD), and related cognitive disorders, represent a significant and growing public health challenge, particularly in aging populations. Despite advances in pharmacological treatments, therapeutic options for cognitive decline and neurodegeneration remain limited. Recent interest has shifted towards nutraceuticals— bioactive compounds derived from food or natural sources—as promising adjuncts or alternatives in the management of these conditions. This review examines how nutraceuticals can help …
Published in International Journal of Brain Sciences · Vol. 2, Issue 1, 2025 · pp. 1–9 Read article
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The Role of Artificial Intelligence in Mental Health: Applications in Neurodegenerative Disorders
Abstract: Artificial intelligence (AI) has significantly changed many aspects of medical care, particularly the early evaluation, therapy, and management of neurodegenerative illnesses like Alzheimer's, disease, Parkinson's diseases, and Huntington's diseases. The current research explores the application of AI in mental health with respect to neurological disorders, especially advancements in cognitive examination, neuroimaging analysis, predictive modeling, and customized therapy modalities. Artificial intelligence (AI) systems have shown enormous potential in detecting minute biomarkers …
Published in Research and Reviews : A Journal of Biotechnology · Vol. 15, Issue 3, 2025 · pp. 34–40 Read article
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Enhanced Multimodal Disease Prediction Using Hybrid Ensemble Learning and AutoML Techniques
Abstract: The integration of hybrid ensemble learning and automated machine learning (AutoML) is revolutionizing disease prediction by addressing the complexity, imbalance, and high dimensionality inherent in medical datasets. This paper proposes an advanced pipeline that combines diverse ensemble learning models with AutoML-based optimization to predict chronic diseases such as kidney diseas-e, Parkinson’s disease, and lung cancer. Publicly available datasets from UCI and PhysioNet repositories were preprocessed using outlier removal, normalization, and …
Published in Research and Reviews : Journal of Computational Biology · Vol. 15, Issue 1, 2026 Read article
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Effect of Toxoplasma gondii on some Neurotransmitter Levels in Patients with Toxoplasmosis Infection
Abstract: Background: The study of Toxoplasma gondii on some neurotransmitter levels in patients with toxoplasmosis infection is one of the challenges of sustainable development. Toxoplasma gondii is a parasite that can alter host behavior by affecting neurotransmitters of the host. Aim: To diagnose if there are differences in neurotransmitter levels in infected people by toxoplasmosis and healthy people to predict the psychological and neurological diseases. Methods: The study included collecting 60 …
Published in Research and Reviews : A Journal of Life Sciences · Vol. 16, Issue 1, 2026 · pp. 1–8 Read article
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MicroRNAs in Animal Behavior: Regulation of Memory and Decision-Making in Mammals
Abstract: MicroRNAs are small, non-coding RNA molecules that play a crucial role in post-transcriptional regulation of gene expression. In recent years, their significance has extended beyond cellular development and disease regulation, as emerging evidence suggests they are critical mediators in complex behavioral processes, including learning, memory, and decision-making. This article explores the role of miRNAs in regulating neural plasticity and cognitive functions in mammals, emphasizing their involvement in memory formation and …
Published in Research and Reviews : Journal of Veterinary Science and Technology · Vol. 13, Issue 3, 2024 · pp. 21–25 Read article
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Assessing the Clinical Efficacy and Safety of Semaglutide: A Comprehensive Study
Abstract: Semaglutide, a glucagon-like peptide-1 receptor agonist (GLP-1RA), has emerged as a versatile therapeutic agent with significant potential in managing a range of diseases. Extensive research has demonstrated its efficacy in treating obesity, type 1 and type 2 diabetes, and even neurodegenerative disorders like Parkinson’s disease. This comprehensive review examines the principal outcomes derived from clinical trials that incorporate semaglutide alongside other GLP-1 agonists, with particular emphasis on the mechanisms underlying …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 14, Issue 3, 2024 · pp. 96–104 Read article
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Samelisant, an H3 Receptor Agonist as an Anti-Alzheimer Potential – A Pilot Study on Molecular Docking
Abstract: Neurodegenerative diseases have become more prevalent and about 55 million of the population are affected by dementia globally. One of the most important neurodegenerative diseases is Alzheimer’s disease which is known for its effect on memory and cognitive impairment. Alzheimer’s disease (AD) is an area of intense scientific investigation due to its high prevalence and the lack of a definitive cure. Amyloid precursor protein plays a central role in Alzheimer’s …
Published in International Journal of Brain Sciences · Vol. 3, Issue 1, 2026 · pp. 15–26 Read article
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Gut Microbial Metabolites in Inflammatory, Metabolic, and Neurologic Disorders.
Abstract: The human gut microbiota transforms dietary and hostderived substrates into a diverse array of metabolites—including shortchain fatty acids (SCFAs), hydrogen sulfide (H₂S), bile acid derivatives, indoles, trimethylamine Noxide (TMAO), branchedchain amino acid (BCAA) derivatives, and lipopolysaccharide (LPS)—that act as key signaling mediators along epithelial, immune, endocrine, and neural axes. These metabolites regulate barrier integrity, energy homeostasis, inflammation, and gut–brain communication and are increasingly implicated in the pathogenesis of inflammatory bowel …
Published in Emerging Trends in Metabolites · Vol. 3, Issue 1, 2026 · pp. 58–64 Read article
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AI Approaches in Gait and Posture Analysis: A Review
Abstract: This review synthesizes current research on the application of artificial intelligence (AI) in gait and posture analysis, focusing on methodologies, algorithms, and clinical applications. It examines the use of machine learning (ML) and deep learning (DL) techniques to extract relevant features from sensorderived data, offering objective, and automated assessments that surpass traditional methods. A systematic literature review was conducted, analyzing studies that utilized AI for gait and posture analysis with …
Published in Research and Reviews : Journal of Computational Biology · Vol. 14, Issue 3, 2025 · pp. 1–3 Read article
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Development of Spanish Version of Home-Based Video Module of Balance Exercises for Peripheral Vestibular Disordered Patients
Abstract: Any disturbances affecting one or more of the balance organs lead to imbalance difficulties and as a consequence, the quality of life of the affected individuals can be seriously affected, especially if the episodes end with injuries or even fatal accidents. Bal Ex is the first home-based video guided workout that was created by Zainun and her colleagues in 2009. Ten languages are currently supported by Bal Ex, including Cantonese, …
Published in International Journal of Brain Sciences · Vol. 1, Issue 2, 2024 · pp. 33–41 Read article
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Integrating Network Pharmacology and Molecular Docking to Assess Rutin’s Pharmacological Properties
Abstract: Objectives: In the present research, the network pharmacology process was applied to determine the underlying mechanism of the pharmacological properties of Rutin. Network pharmacology was utilized to reveal the interactions between medications and the targets of illnesses, and it is capable of completely articulating the complexity between diseases and medications. The identification of diverse drug-target interactions using network pharmacology may be utilized to discover novel medications for difficult conditions like …
Published in International Journal of Molecular Biotechnological Research · Vol. 1, Issue 1, 2023 · pp. 20–33 Read article
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Marine-Derived Pharmaceuticals: Unlocking the Ocean's Potential for Human Health
Abstract: The ocean, covering 70% of the Earth’s surface, is a rich source of unique bioactive compounds with potential therapeutic applications. This review aims to highlight the significance of marine-derived pharmaceuticals in human health, focusing on clinically approved and commercially available medications. The review covers various marine-derived compounds, their structural features, modes of action, and applications in treating diseases, such as cancer, diabetes, and neurodegenerative disorders. The review identifies several marine-derived …
Published in Research & Reviews: A Journal of Pharmacognosy · Vol. 12, Issue 1, 2025 · pp. 1–12 Read article
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A Research Study on Cognitive Health Benefits of Nicotine to the Human Body
Abstract: Background: Nicotine has been primarily known for its addictive properties and associated health risks, particularly in tobacco products. However, recent research has highlighted nicotine’s potential cognitive health benefits, especially in neurodegenerative diseases like Alzheimer’s and Parkinson’s. This study investigates smoking prevalence across mental health conditions, and cognitive impairments in various psychiatric disorders, and explores the possible cognitive health benefits of nicotine. Methods: Data on age and gender distribution, smoking prevalence, …
Published in Research & Reviews: A Journal of Drug Design & Discovery · Vol. 12, Issue 1, 2025 · pp. 16–23 Read article
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A Perspective Review on Role of Environmental Pollutants in Developing Neurodegenerative Diseases
Abstract: As human society progresses towards industrialization, an excess number of environmental pollutants are released to our ecosystem, which significantly contribute in causing various health issues primarily associated with neurodegenerative diseases such as cognitive disorder, dementia, anxiety, Alzheimer, Parkinson etc. Because of their high global occurrence, these diseases have attracted attention in recent decades, however, the etiology of these diseases remains unclear. Pollutants are discharged into the environment by natural events …
Published in Research and Reviews : A Journal of Life Sciences · Vol. 14, Issue 2, 2024 · pp. 1–18 Read article
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Aquatic Ecosystems: A Review on Prospecting of Anticancer Molecules from Fungi & Other Microbes
Abstract: Marine biota; namely, actinomycetes, bacteria, fungi, microalgae, green algae, oceanic weeds, mangroves, and other extremophiles constitute about 90% of the oceanic biomass. The organisms are taxonomically diverse, biologically productive/active, and biochemically unique. These unique biochemiques may act as a great source for the discovery of new bioactive molecules, including anticancer drugs. The marines produce medicinally potent biochemicals; namely, sulfated saccharides, polyphenols, and, sterols. Only a few of these alkaloids have …
Published in International Journal of Fungi · Vol. 1, Issue 2, 2024 · pp. 1–22 Read article
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Stem Cell Therapy: Advancements, Applications, and Future Prospects in Regenerative Medicine
Abstract: Stem cell therapy has come up as a revolutionary technique in regenerative medicine living up to the promise in treating numerous diseases and injuries. The latest discoveries made in the field of stem cell research such as the introduction of gene editing technology like CRISPR and the creation of the 3D bioprinting process have increased the accuracy and efficacy of stem cell-based therapies. Examples include cardiac regeneration and repair of …
Published in International Journal of Cell Biology and Cellular Functions · Vol. 4, Issue 1, 2026 Read article