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143 articles for “Novel Strategies”
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Systematic Analysis of the Therapeutic Potential of Bacopa monnieri: A Wonder Therapeutic Plant
Abstract: Bacopa monnieri (L.) Wettst., a well-known perennial creeping herb, native to parts of America, the African subcontinent, and South Asia, had been a well-known nootropic plant, documented in ancient Indian systems of medicine, Ayurveda. The dynamic variations in the phytocompounds consortia, regulated by abiotic cultivation conditions and germplasm, provided a paradigm shift towards the exploring profound therapeutic effect of the plant along with advancements in scalable cultivation strategies. Tailoring the …
Published in Research & Reviews : Journal of Herbal Science · Vol. 15, Issue 2, 2026 Read article
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Enhancing Physical Properties of Unfilled SBR Rubber Compounds using Nano CaCO3 Additive
Abstract: The push for rubber compounds with improved characteristics in the rubber industry has sparked extensive research strategies for developing novel rubber compounds with improved properties like tensile strength, abrasion resistance, rolling resistance and flex properties etc., especially for the automobile industry. To intensify the processability, performance, and look of materials such as plastics, rubbers, paints, color, printing, and lubricants, additives are often employed to improve their qualities and overall value …
Published in Journal of Polymer & Composites · Vol. 13, Issue 4, 2025 · pp. 40–49 Read article
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Proof-of-Minimum Privacy Leak Consensus Strategy in Blockchain
Abstract: In this study, we propose a novel consensus algorithm to preserve the security and privacy of a transaction. We propose a Proof-of-Minimum Privacy Leak consensus strategy. This means that the competing nodes which participate in the competition to mine the next block should give a proof of minimum privacy leak during its transaction. Only this proof will give highest votes to that node, and it will be elected as the …
Published in E-Commerce for Future & Trends Read article
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Improving Node Efficiency in Wireless Sensor Networks Using Advanced Clustering and Routing Techniques
Abstract: Many Internet of Things (IoT) applications, such as disaster relief, smart buildings, smart farming, and healthcare monitoring, have made use of wireless sensor networks (WSN). It is one of the alternatives to address different IoT difficulties in different contexts. One of the main problems with sensor networks is power efficiency. WSN operated on the Client-Server (CS) architecture in the past, however researchers suggested Mobile Agent (MA) based WSN to increase …
Published in Recent Trends in Sensor Research & Technology · Vol. 11, Issue 2, 2024 · pp. 35–64 Read article
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A Comprehensive Analysis of Novel Liposomes: Categorization, Approach, Description, and Present Formulations
Abstract: Liposomes have gained attention as a promising drug delivery system, which come with the advantages of biocompatibility, ability to load hydrophilic and hydrophobic drugs, and they can function for targeted drug delivery. In this regard, this paper offers a comprehensive overview on novel liposomes, including classification, formulation strategies, detailed structures, and current pharmaceutical applications. Recent advances in liposomal drug delivery systems includes, new liposomal architectures (i.e. stealth, targeted, stimuli-responsive, hybrid …
Published in Research & Reviews: A Journal of Drug Design & Discovery · Vol. 12, Issue 2, 2025 · pp. 15–20 Read article
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Distinctive Approaches for Improving the Aqueous Solubility of BCS Class II Drugs
Abstract: The most difficult feature of many novel chemical entities is their solubility behaviour, as 60 percent of new promising products suffer solubility limitations. This is the most common reason for novel medicine compounds failing to reach the market or performing to their full potential. The proportion of the aqueous phase when the solution is in equilibrium with the pure substance in its normal phase is referred to as aqueous solubility. …
Published in Research & Reviews: A Journal of Drug Design & Discovery · Vol. 8, Issue 3, 2023 · pp. 52–56 Read article
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A Comprehensive Review on Piezoelectric Composites for Energy Harvesting and Sensing
Abstract: The capacity of piezoelectric composites to transform mechanical energy into electrical energy and vice versa has drawn a lot of interest recently. This property makes them very appealing for use in energy harvesting and sensing applications. These materials combine the high piezoelectric performance of ceramics with the mechanical flexibility and processability of polymers or other matrices, enabling a wide range of practical uses in flexible electronics, wearable systems, and embedded …
Published in International Journal of Electro-Mechanics and Material Behaviour · Vol. 3, Issue 1, 2025 · pp. 19–24 Read article
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Space Pharmacy for Human Space Exploration: Overcoming Drug Stability, Packaging Challenges, Pharmacokinetic Variations, and Developing Innovative On-Demand Therapeutic Solutions for Long- Duration Missions Beyond Earth
Abstract: As humankind prepares for prolonged space exploration and the establishment of lunar and Martian habitats, ensuring reliable access to safe and effective medicines has emerged as a critical challenge. The evolving discipline of space pharmacy addresses the unique pharmaceutical needs of astronauts in microgravity and radiation-rich environments, where drug stability, packaging, and pharmacokinetics are markedly different from conditions on Earth. Traditional dosage forms often undergo accelerated degradation, while altered fluid …
Published in Trends in Drug Delivery · Vol. 13, Issue 1, 2026 · pp. 32–47 Read article
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Emerging Therapies in Respiratory Tract Infections: Current Advances and Future Perspectives
Abstract: The impact of respiratory tract infections (RTI) as a global public health problem continues to be high morbidity and mortality rates. The development of novel therapeutic approaches stemmed from the fact that conventional treatment strategies, antibiotics, antivirals, antifungals etc. have become increasingly ineffective because of rise of antimicrobial resistance (AMR). Next generation therapies, such as novel antimicrobial agents, host directed therapies and novel drug delivery systems have come on the …
Published in Recent Trends in Infectious Diseases · Vol. 2, Issue 2, 2025 · pp. 17–25 Read article
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Developing an AI-Based Novel Forecasting Framework for Surface Irregularity in Metal Matrix Materials
Abstract: Surface irregularity in metal matrix materials (MMM) signifies the deviations from smoothness, influencing structural integrity and performance frequently arising from the manufacturing process along with intrinsic material characteristics that influence effectiveness. Limitations in data, model interpretability and complexity are the difficulties that impede artificial intelligence (AI) based surface irregularity in MMM. In this study, we suggested a novel framework of Gaussian regression fused multi-strategy adaptive boosting classifier (GR-MABC) for the …
Published in Journal of Polymer & Composites · Vol. 12, Issue 5, 2024 · pp. 48–56 Read article
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Development of Polymer-based Mulch Films for Disease Suppression
Abstract: Gerbera jamesonii [Gerbera daisy) is a popular flowering plant susceptible to various microbial diseases. This paper explores disease control strategies for gerberas, focusing on the potential of novel polymer-based mulch films. Conventional mulching practices offer benefits in gerbera cultivation, including weed suppression that helps control pathogens. However, limitations associated with traditional mulch materials necessitate exploring alternative solutions. This study investigates the development of biodegradable polymer-based mulch films specifically designed for …
Published in Journal of Polymer & Composites · Vol. 13, Issue 1, 2025 · pp. 856–863 Read article
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Design, Synthesis, and Spectroscopic Elucidation of 3-Methyl-1-Phenylpyrazol-5-One: A Cheminformatics-Aided Approach to Heterocyclic Drug Scaffolds
Abstract: Pyrazolone, a notable heterocyclic compound, has drawn increasing interest due to its broad pharmacological profile and structural versatility. The synthesis, characterisation, and biological assessment of new pyrazolone derivatives are examined in this work. A comprehensive review of existing synthetic strategies is presented, emphasizing green and efficient methodologies. Novel derivatives were synthesized using varied starting materials and catalytic systems, followed by structural confirmation through spectroscopic analyses, including NMR, IR, and mass …
Published in International Journal of Cheminformatics · Vol. 3, Issue 1, 2025 · pp. 29–40 Read article
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Urban Planning and Design Approaches for Redevelopment: Case of Indian Railway Stations Redevelopment
Abstract: Urban society’s spatial and functional needs are reflected in the theories that revolve around planning and design. These theories evolve and shape urban policies that are the frameworks for the future. The practice of these theories differs across the world because of the unique history and geography of urban areas. However, theories encompass a wide range of subjects that occur repeatedly. It is important to understand and contextualise the theoretical …
Published in International Journal of Urban Design and Development · Vol. 4, Issue 2, 2026 · pp. 25–35 Read article
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Antimicrobial Peptides and Bacteriophages as Next-Generation Alternatives to Conventional Antibiotics
Abstract: The growing threat of antibiotic-resistant bacteria has underscored the urgent need for innovative alternatives to conventional antibiotics. Antimicrobial peptides (AMPs) and bacteriophages are gaining recognition as next-generation therapeutics due to their distinct mechanisms of action and ability to target resistant pathogens effectively. AMPs, which can be natural or synthetic, disrupt microbial membranes and offer broad-spectrum antimicrobial activity with a reduced likelihood of resistance development. Bacteriophages, as bacteria-specific viruses, provide precise …
Published in International Journal of Antibiotics · Vol. 2, Issue 1, 2025 · pp. 9–27 Read article
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Veterinary Immunology in Zoonotic Disease Control
Abstract: Zoonotic diseases, which are transmissible between animals and humans, pose a significant threat to global public health, food security, and economic stability. Veterinary immunology plays a pivotal role in understanding host–pathogen interactions, developing preventive strategies, and mitigating the impact of these diseases. Animals serve as reservoirs for a variety of pathogens, including viruses, bacteria, and fungi, which can persist asymptomatically or cause clinical disease. Understanding the immune mechanisms in both …
Published in Research and Reviews : Journal of Veterinary Science and Technology · Vol. 14, Issue 3, 2025 · pp. 36–43 Read article
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Immune Dysregulation and Cytokine Circuitry in Genital Endometriosis: Mechanistic Insights and Next-Generation Immunotherapeutic Strategies
Abstract: Genital endometriosis is increasingly recognized as an immune-mediated inflammatory disorder driven by complex interactions between dysregulated immune cells, cytokine hubs, and microbiome-derived modulators. This review introduces a novel “immune–cytokine circuitry” framework that unifies innate and adaptive immune abnormalities with key cytokine loops sustaining chronic inflammation, angiogenesis, neuroinflammation, and immune tolerance. Within this circuitry, macrophage polarization, dendritic cell immaturity, NK-cell anergy, Treg expansion, Th17 amplification, and B-cell–mediated autoimmunity converge to establish …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 16, Issue 1, 2026 · pp. 06–16 Read article
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Development of a Novel Therapeutic Approach Using RNA Interference for Targeting Viral Genes
Abstract: RNA interference (RNAi) is a ground breaking therapeutic strategy that holds immense promise for targeting viral genes in the treatment of viral infections. This approach leverages the natural gene-silencing mechanisms of RNAi to inhibit viral replication and expression at the molecular level, providing a precise and adaptable method to counteract viral pathogens, including influenza, HIV, and hepatitis viruses. Recent advancements in RNAi technology have enabled the development of highly specific …
Published in International Journal of Virus Studies · Vol. 1, Issue 2, 2024 · pp. 12–22 Read article
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Pharmacokinetic Profiling and Molecular Docking of Carvacrol and Structural Analogs: Targeting Quorum Sensing Proteins to Disrupt Biofilm-Mediated Antimicrobial Resistance in Multidrug-Resistant Bacterial Pathogen
Abstract: Antibiotic resistance, particularly in Pseudomonas aeruginosa, has become a major global health threat, exacerbated by the organism's ability to form biofilms and regulate virulence through quorum sensing (QS). The LuxR and LasR receptors are key regulators in this process, influencing both pathogenicity and antibiotic resistance. This study investigates potential QS inhibitors targeting these receptors as a strategy to mitigate antibiotic resistance. The primary objective was to identify novel ligands that …
Published in International Journal of Biochemistry and Biomolecule Research · Vol. 3, Issue 2, 2025 · pp. 43–61 Read article
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Partitioning Dynamics of Nutrients in Transition Dairy Cows: Metabolic, Hormonal, and Cellular Mechanisms Affecting Lactation and Fertility
Abstract: This review critically examines nutrient partitioning dynamics in dairy cows during the transition phase, a period that profoundly affects lactation and reproductive performance. During this phase, cows experience extensive physiological changes that alter nutrient requirements and utilization, making effective management essential for health and productivity. The review synthesizes current research on mechanisms of nutrient partitioning, with particular attention to energy, protein, and mineral balance, which are crucial for optimizing milk …
Published in International Journal of Nutritions · Vol. 3, Issue 1, 2026 Read article
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Liposomes as Therapeutic Vehicles: Advancing Targeted Drug Delivery in Healthcare
Abstract: Liposomes represent an innovative approach to targeted drug delivery. These tiny, lipid-based vesicles can encapsulate medications, allowing them to travel directly to diseased cells while minimizing impact on healthy tissues. By using liposomes, medications can improve their effectiveness while reducing side effects, leading to better overall treatment results.. Their structure enables a controlled release of the drug, which can be particularly beneficial for therapies requiring sustained action. This technology holds …
Published in Research & Reviews: A Journal of Drug Design & Discovery · Vol. 11, Issue 3, 2024 · pp. 39–46 Read article