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49 articles for “Hydrophobicity”
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Molecular Pharmacokinetics and Structural Docking of Phenolic Acids for Targeting NF-κB Pathway Components in Inflammation and Fibrosis: A Computational Approach Toward Therapeutic Discovery
Abstract: Inflammation and Fibrosis are critical pathological processes associated with various chronic diseases, often mediated by the nuclear factor kappa-light-chain-enhancer of activated B cells (NF-κB) signaling pathway. This study investigates the therapeutic potential of phenolic acids as modulators of the NF-κB pathway, aiming to identify novel ligands that can effectively interact with key components of this signaling cascade. A comprehensive computational approach was employed, utilizing molecular docking, pharmacological screening, and post-docking …
Published in International Journal of Cell Biology and Cellular Functions · Vol. 3, Issue 1, 2025 · pp. 14–31 Read article
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Wettability and Physiothermal Analysis of Silver-Reinforced Eggshell-Derived Hydroxyapatite Based Biocomposite
Abstract: Hydroxyapatite (HAp), a biocompatible ceramic material, has garnered significant interest in medical applications due to its natural bone type replica. The current study investigates the physical, wettability, and thermal properties of a novel HAp derived from eggshell waste and reinforced with silver nanoparticles at 0.0, 0.1, 0.2 and 0.5 weight % concentration using chemical precipitation method and termed as HAP0.0Ag, HAP0.1Ag, HAP0.2Ag and HAP0.5Ag respectively. As observed, the Fourier transform …
Published in Journal of Polymer & Composites · Vol. 13, Issue 3, 2025 · pp. 300–314 Read article
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Microsphere-Based Drug Delivery: A Critical Review of Innovations and Applications
Abstract: Microspheres have emerged as a revolutionary approach in pharmaceutical sciences, offering controlled and targeted drug delivery with improved bioavailability, stability, and patient compliance. These spherical carriers, ranging from nanometers to micrometers in size, can encapsulate both hydrophilic and hydrophobic drugs, enabling sustained and site-specific release. The development of microspheres has been significantly driven by the need to enhance drug efficacy while minimizing systemic side effects. This review provides a comprehensive …
Published in Trends in Drug Delivery · Vol. 12, Issue 2, 2025 · pp. 52–59 Read article
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Synthesis of Thermal Resistant and Transparent Al2O3 Reinforced Epoxy-Based Composite Coatings
Abstract: This study explores the influence of thermal treatment on the structural, optical, and surface wettability characteristics of epoxy-based composite coatings reinforced with 3 wt.% aluminum oxide (Al₂O₃) nanoparticles. The coatings were synthesized via a dip-coating method on carbon fiber substrates and subjected to controlled thermal treatments at 300 °C, 400 °C, and 500 °C to assess their thermal resilience. X-ray diffraction (XRD) analysis confirmed the structural integrity of the composite …
Published in Journal of Polymer & Composites · Vol. 13, Issue 3, 2025 · pp. 178–183 Read article
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Pharmacokinetic Profiling and Molecular Docking of Carvacrol and Structural Analogs: Targeting Quorum Sensing Proteins to Disrupt Biofilm-Mediated Antimicrobial Resistance in Multidrug-Resistant Bacterial Pathogen
Abstract: Antibiotic resistance, particularly in Pseudomonas aeruginosa, has become a major global health threat, exacerbated by the organism's ability to form biofilms and regulate virulence through quorum sensing (QS). The LuxR and LasR receptors are key regulators in this process, influencing both pathogenicity and antibiotic resistance. This study investigates potential QS inhibitors targeting these receptors as a strategy to mitigate antibiotic resistance. The primary objective was to identify novel ligands that …
Published in International Journal of Biochemistry and Biomolecule Research · Vol. 3, Issue 2, 2025 · pp. 43–61 Read article
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A Comprehensive Analysis of Novel Liposomes: Categorization, Approach, Description, and Present Formulations
Abstract: Liposomes have gained attention as a promising drug delivery system, which come with the advantages of biocompatibility, ability to load hydrophilic and hydrophobic drugs, and they can function for targeted drug delivery. In this regard, this paper offers a comprehensive overview on novel liposomes, including classification, formulation strategies, detailed structures, and current pharmaceutical applications. Recent advances in liposomal drug delivery systems includes, new liposomal architectures (i.e. stealth, targeted, stimuli-responsive, hybrid …
Published in Research & Reviews: A Journal of Drug Design & Discovery · Vol. 12, Issue 2, 2025 · pp. 15–20 Read article
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High-Performance Biodegradable Films from Bamboo Derived Cellulose Nanofibers and Silk Fibroin: Engineering Sustainable Polymer Composites
Abstract: This research presents the advancement of biodegradable composite films from cellulose nanofibers (CNFs) extracted from bamboo and silk fibroin (SF) derived from Bombyx mori cocoons. CNF/SF composites were fabricated in three different compositions—CS10, CS30, and CS50—via aqueous blending and solution casting, followed by ethanol-induced β-sheet stabilization. Mechanical testing confirmed a considerable enhancement in tensile strength from 72 MPa (CS10) to 112 MPa (CS50), while Young’s modulus improved from 2.4 GPa …
Published in Journal of Polymer & Composites · Vol. 13, Issue 4, 2025 · pp. 256–265 Read article
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Analyzing the Role of Fiber Composition in Drying Behavior: A Comparative and Predictive Approach
Abstract: This research presents a comprehensive analysis of the drying behavior and thermal response of three distinct fabric types: 100% Cotton, 100% Polyester, and a Polyester blend (65/35), under meticulously controlled environmental conditions. The Polyester blend (65/35) consists of 65% Polyester and 35% Cotton, combining characteristics of both fibers. The investigation focuses on understanding how fiber composition impacts drying time, moisture retention, and thermal characteristics. Experimental trials were conducted using standardized …
Published in Journal of Polymer & Composites · Vol. 13, Issue 5, 2025 · pp. 1–11 Read article
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Polymer Chemistry in Nutraceutical Composites: Exploring Natural Polymers and Binding Systems in a Bamboo-Enhanced Formulation
Abstract: Polymer chemistry underpins the development of advanced nutraceutical composites, blending natural polymers with functional ingredients for health benefits. This study examines a novel nutraceutical formulation comprising ragi (16.39 g/100g), wheat (12.29 g/100g), soybean (12.29 g/100g), buffalo milk (16.39 g/100g), buffalo butter (4.13 g/100g), bamboo extract (0.90 g/100g), and auxiliary components (37.61 g/100g, including fats, sugars, and proteins). Natural polymers—proteins from soybean and milk, polysaccharides from ragi and wheat—form a macromolecular …
Published in Journal of Polymer & Composites · Vol. 13, Issue 6, 2025 · pp. 878–884 Read article
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Polymer Chemistry in Sustained-Release Herbal Composites: Designing a Stable Euphorbia tithymaloides Topical System with Phospholipid and Polymer Matrices
Abstract: Polymer chemistry enables the stabilization and sustained release of herbal actives, critical for topical therapeutic applications. This study explores a novel process for preparing a stable, sustained-release topical composition of Euphorbia tithymaloides, leveraging polymer-based systems. Ethanolic extract (50 mg) of the plant, rich in unstable sugar moieties (e.g., D-ribose) and sterols (e.g., stigmasterol), is encapsulated within a phospholipid matrix of phosphatidylcholine (50–100 mg) and cholesterol (50–100 mg). This lipid-polymer complex, …
Published in Journal of Polymer & Composites · Vol. 13, Issue 6, 2025 · pp. 165–171 Read article
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AI-Assisted Defect Detection in Polymer Composite Insulators Using an Optimised Ensemble Deep Learning Framework for Structural Health Monitoring
Abstract: Polymer composite insulators, particularly those made from silicone rubber and epoxy resins, are increasingly adopted in high-voltage transmission systems due to their superior electrical insulation, lightweight design, hydrophobicity, and environmental durability. Despite their advantages, these materials are susceptible to surface degradation, mechanical cracking, and flashover under prolonged exposure to environmental pollutants, thermal stress, and electrical aging. Accurate, real-time condition assessment of these composite insulators is critical for ensuring operational safety, …
Published in Journal of Polymer & Composites · Vol. 13, Issue 6, 2025 · pp. 253–261 Read article
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Self Healing Material: An Introduction
Abstract: Self-healing materials have emerged as a transformative innovation for sustainable infrastructure and advanced applications such as wearable electronics and smart transportation systems. These materials possess the intrinsic ability to repair damage autonomously or with minimal external intervention, thereby extending service life and reducing maintenance costs. Inspired by biological systems, self-healing mechanisms are broadly classified into extrinsic approaches, such as microcapsule and vascular networks based healing, and intrinsic mechanisms involving reversible …
Published in Journal of Polymer & Composites · Vol. 13, Issue 6, 2025 · pp. 604–611 Read article
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Biodegradable and Natural Fiber-Reinforced Polymer Composites for Co-Delivery of Multiple Therapeutic Agents
Abstract: The co-delivery of multiple drugs using advanced nanocarriers has revolutionized targeted therapy in various diseases, particularly in cancer, infectious diseases, and neurological disorders. Multi-layered polymeric nanocarriers (MLPNs) offer a sophisticated platform to encapsulate multiple therapeutic agents with precise control over drug release, bioavailability, and synergistic effects. These nanocarriers are designed with distinct polymer layers that enable sequential or simultaneous drug release based on stimuli-responsive mechanisms such as pH, temperature, and …
Published in Journal of Polymer & Composites · Vol. 13, Issue 6, 2025 · pp. 406–419 Read article
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Engineered Hybrid Nanoclay-Infused Nano-Polymers for Multifunctional Anti-Corrosive Coatings
Abstract: Polymer nanocomposites reinforced with layered nanofillers have emerged as an effective route to enhance structural stability in protective coating applications. Polymer–clay nanocomposites also provide a promising route to enhance mechanical robustness and environmental durability in coating systems. In this study, a hybrid epoxy–polyurethane (EPU) coating was reinforced using organo-modified montmorillonite (o-MMT) and layered double hydroxide intercalated with 2-mercaptobenzothiazole (LDH–MBT). Uniform dispersion and interfacial anchoring between the nanoclays and polymer chains …
Published in Journal of Polymer & Composites · Vol. 14, Issue 1, 2026 · pp. 40–53 Read article
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Bio-Derived TPS–Lignin Hybrid Composites Reinforced with Modified Coir and Plantain Fibers for Eco-Efficient Structural Applications
Abstract: This study develops bio-derived polymer composites using a thermoplastic starch–lignin (TPS–lignin) matrix reinforced with alkali-treated coir and plantain fibers for sustainable load-bearing applications. The TPS–lignin matrix was formulated using cassava starch, glycerol, and 10 wt% lignin, while coir and plantain fibers were surface-modified using 5 wt% NaOH to enhance interfacial compatibility. Composite laminates were fabricated with varying fiber loadings (10–40 wt%) through melt-mixing and hot-press compression. Tensile, thermal, morphological, and …
Published in Journal of Polymer & Composites · Vol. 14, Issue 1, 2026 · pp. 136–145 Read article
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Elucidation of Physical Structural Stability of Nickel Nanoparticles Additive-Based Magnetorheological Grease
Abstract: This study investigates the influence of nickel nanoparticles on the physical properties and structural stability of magnetorheological grease (NMRG) as a smart composite. The incorporation of nickel nanoparticles aims to mitigate issues commonly observed in conventional magnetorheological grease (MRG), including particle aggregation within the fibrous matrix, limited material performance, and deformation instability. NMRG samples containing 1–5 wt% nickel nanoparticles were prepared using a mechanical stirring method. The tests focused on …
Published in Journal of Polymer & Composites · Vol. 14, Issue 1, 2026 · pp. 191–215 Read article
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Development and Application of Advanced Materials for Oil Spill Cleanup and Contaminant Removal
Abstract: Oil spills and environmental contaminants representing critical challenges to ecosystems and human health, demanding innovative and effective solutions. Advanced materials have emerged as transformative tools in addressing these issues, offering superior efficiency and sustainability compared to conventional methods. They are environmental and ecological threats, necessitating effective cleanup and removal strategies. The development and application of advanced materials are developing promising solutions for addressing the challenges. This study focuses on the …
Published in Journal of Water Pollution & Purification Research · Vol. 13, Issue 1, 2026 · pp. 17–25 Read article
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Surfactant-Mediated Synthesis and Stabilization of Colloidal Nanoparticles in Aqueous Media: A Preliminary Study on Controlling Parameters
Abstract: Surfactants dissolved in water possess a distinctive tendency to accumulate at surfaces or interfaces, a process that involves the migration of surfactant molecules from the bulk liquid phase to the interfacial region. This adsorption tendency of surfactants is being exploited in stabilization of the Nanoparticles (NPs) synthesized through colloidal chemistry routes. In present research, preliminary studies on controlling parameters involving various surfactants has been carried out to standardized the chemical …
Published in Journal of Materials & Metallurgical Engineering · Vol. 16, Issue 1, 2026 · pp. 25–35 Read article
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Exploration of Diverse Epoxy-Based Surface Coating Methods for Enhancing Anticorrosion Characteristics
Abstract: Epoxy-based polymers, commonly referred to as polyepoxides, constitute one of the most versatile and widely adopted categories of polymeric materials due to their exceptional structural, mechanical, and chemical characteristics. Their unique macromolecular framework enables strong interfacial bonding, high mechanical stability, and superior resistance to environmental and chemical degradation, positioning them as advanced alternatives to many traditional organic corrosion inhibitors that often fail under prolonged exposure to aggressive conditions When polyepoxides …
Published in Journal of Polymer & Composites · Vol. 14, Issue 2, 2026 · pp. 167–177 Read article
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Development and Thermal-Soiling Performance Evaluation of Boron-Nitride Reinforced Polymer Nanocomposite Coatings for Solar Photovoltaic Applications
Abstract: Surface heating, dust buildup, and weakening triggered by ultraviolet (UV) light all have a vast effect on the long-term performance of solar photovoltaic (PV) modules. These issues all lower power conversion efficiency in real-world open-air circumstances. A nanocomposite coating built on fluoropolymer (FEP) that is reinforced with hexagonal boron nitride (h-BN) nanoparticles is invented by this study to enhance thermal dissipation, optical transmission, and resistance to dirt at the same …
Published in Journal of Polymer & Composites · Vol. 14, Issue 2, 2026 · pp. 218–223 Read article