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75 articles for “Design-Down Approach”
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Algebraic Foundations of AES (Advanced Encryption Standard): Group Theory and Finite Field Applications in Symmetric Cryptography
Abstract: This paper presents a mathematical study of symmetric cryptographic algorithms, with a particular emphasis on the Advanced Encryption Standard (AES), which is one of the most widely used encryption schemes in modern security applications. The study highlights how abstract mathematical frameworks such as group theory, finite fields, and vector space concepts provide the foundation for the design, implementation, and analysis of AES. By approaching the algorithm from a mathematical perspective, …
Published in Recent Trends in Mathematics · Vol. 2, Issue 1, 2025 · pp. 12–16 Read article
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Enhancing Surface Roughness in the Taguchi Method for Turning Alloy Steel in Wet and Dry Environments
Abstract: The present investigation focuses on evaluating the performance of turning operations in alloy steel with particular emphasis on the effect of cutting parameters on surface roughness. In the machining of alloy steel, tool life and surface integrity are significantly influenced by parameters such as spindle speed, depth of cut, and feed rate. Among these, feed rate has been observed to exert the most prominent effect on surface roughness. To systematically …
Published in International Journal of Robotics and Automation in Mechanics · Vol. 3, Issue 2, 2025 · pp. 1–6 Read article
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Envirosense Nexus: IoT-Driven Precision Waste Management for Urban Sustainability
Abstract: In modern urban environments, the improper handling of waste has become a significant issue, particularly due to insufficient and inefficient management of trash collection. This growing problem is leading to unhygienic conditions and pollution, requiring the introduction of smart waste disposal systems. To address this, we propose the development of an Internet of Things (IoT)-based intelligent trash bin that can autonomously detect, monitor, and report its waste levels. The system …
Published in International Journal of Robotics and Automation in Mechanics · Vol. 2, Issue 2, 2024 · pp. 26–31 Read article
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From Humours to Metabolism: An Integrative Review of Obesity Management in Unani Medicine
Abstract: Unani Medicine, a traditional complementary and alternative medicine (CAM) system, adopts a holistic, temperament-based approach to disease prevention and management. In classical Unani literature, obesity is described as Simān-e-Mufriṭ, a pathological condition arising from humoral imbalance, particularly the predominance of phlegm (Balgham) and derangement of temperament (Su’-e-Mizāj), most commonly of a cold and moist nature. This condition is attributed to a sedentary lifestyle, weakened digestive and metabolic faculties, and excessive …
Published in International Journal of Nutritions · Vol. 3, Issue 2, 2026 Read article
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Comprehensive Review of the Fundamental and Functional Properties of Crystalline Materials
Abstract: Crystalline materials, characterized by their highly ordered atomic arrangements, serve as the backbone of modern engineering and technology. This review provides a detailed examination of their diverse properties, categorized into mechanical, thermal, electrical, and optical domains. We analyze fundamental mechanical parameters such as the elastic modulus, yield strength, and fracture toughness, alongside functional behaviors like fatigue and creep. The discussion extends to thermal transport and expansion, electrical conductivity and resistivity, …
Published in International Journal of Crystalline Materials · Vol. 3, Issue 1, 2026 · pp. 20–24 Read article
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Advancing Cancer Vaccine Development through CRISPR/Cas9 Technologies and Future Opportunities
Abstract: The advent of CRISPR/Cas9 genome editing has revolutionized the cancer immunotherapy market, offering unprecedented precision and versatility in the development of next-generation cancer vaccines. This review examines how CRISPR technologies are being integrated into various stages of cancer vaccine development including neoantigen discovery, dendritic cell engineering, cancer cell reprogramming, and tumor microenvironment modulation. In the area of neoantigen discovery, CRISPR enables rapid identification and validation of tumor-specific mutations, thereby supporting …
Published in International Journal of Vaccines · Vol. 2, Issue 2, 2025 Read article
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The Effect of Attachment Styles on Emotional Regulation Impacting Relationship Satisfaction: An Exploratory Case Study Design
Abstract: This study explores the impact of early attachment experiences, emotional regulation, and relationship dynamics among six participants through a qualitative case study approach. Using thematic and narrative analyses, the research identifies key patterns in emotional suppression, fear of abandonment, trust issues, and self-awareness. Participants' narratives reveal how childhood experiences with caregivers influenced their emotional regulation strategies and attachment styles in adulthood. Findings indicate that those with secure emotional upbringings exhibited …
Published in International Journal of Behavioral Sciences · Vol. 2, Issue 2, 2025 · pp. 1–17 Read article
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A Review on the Interconnection Between Drug Design and Controlled Drug Delivery Systems
Abstract: Drug discovery and delivery are two branches of science that have historically developed as independent areas of discovery – one focused on optimizing the properties of molecules for biological activity, and the other on controlling the rate, site, and duration for drug release. However, in contemporary pharmacy, these two areas have merged into a single integrated approach – where drug discovery and delivery strategies co-influence each other at each point …
Published in Emerging Trends in Personalized Medicines · Vol. 3, Issue 1, 2026 · pp. 47–52 Read article
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Host-Pathogen Coevolution: Implications for Immune Evasion and Pathogen Fitness
Abstract: The interaction between hosts and pathogens represents a continuous evolutionary struggle, shaping both microbial virulence and host immunity. Pathogens employ diverse strategies to evade immune surveillance, ranging from antigenic variation and molecular mimicry to hijacking of host immune checkpoints. Simultaneously, hosts refine innate and adaptive immune mechanisms to counteract infection and limit damage. This reciprocal adaptation, known as host–pathogen coevolution, influences pathogen persistence, transmission, and fitness, while also sculpting immune …
Published in International Journal of Pathogens · Vol. 2, Issue 2, 2025 · pp. 6–10 Read article
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Host Invasion to Immune Evasion: Emerging Concepts in Pathogen Virulence Strategies
Abstract: The interaction between hosts and pathogens represents a continuous evolutionary struggle, shaping both microbial virulence and host immunity. Pathogens employ diverse strategies to evade immune surveillance, ranging from antigenic variation and molecular mimicry to hijacking of host immune checkpoints. Simultaneously, hosts refine innate and adaptive immune mechanisms to counteract infection and limit damage. This reciprocal adaptation, known as host–pathogen coevolution, influences pathogen persistence, transmission, and fitness, while also sculpting immune …
Published in International Journal of Pathogens · Vol. 3, Issue 1, 2026 Read article
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An Extensive Analysis of Computer-Aided Drug Design for Novel Psychotropic and Neurological Substances
Abstract: A comprehensive review of the use of computer-aided drug design (CADD) in the creation of innovative neurologic and neuropsychiatric medications is given in this article. It discusses the challenges in traditional drug discovery approaches and highlights the role of computational methods in accelerating the identification and optimization of drug candidates targeting psychiatric and neurological disorders. The method of finding new drugs has been completely transformed by Computer-Aided Drug Design (CADD), …
Published in International Journal of Brain Sciences · Vol. 1, Issue 2, 2024 · pp. 19–27 Read article
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A Study to Assess the Effectiveness of Body Mechanics Training Programme on Reducing Low Back Pain Among Nursing Officers Working in Selected Hospitals, Bangalore
Abstract: Background: Low Back Pain (LBP) is a common work related injury and costly problem among the nursing profession. Numerous studies indicate a greater occurrence of back pain and work-related back injuries among nursing officers in comparison to other occupations. Prevention of LBP is a very important technique to maintain proper body mechanics. This study aimed to assess the effectiveness of body mechanics training programme on reducing low back pain among …
Published in International Journal of Orthopedic Nursing and Practices · Vol. 2, Issue 1, 2024 · pp. 29–62 Read article
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Microstructural Design and Functional Properties of Polycrystalline Materials
Abstract: Polycrystalline materials, composed of an aggregate of crystallites or grains, are foundational to modern engineering applications due to their versatile functional properties. The microstructural design—encompassing grain size, shape, orientation, phase distribution, and grain boundary characteristics—plays a pivotal role in determining mechanical, thermal, electrical, and magnetic behavior. This abstract explores the intricate relationship between microstructure and functionality, emphasizing how tailored processing techniques such as thermomechanical treatments, sintering, and additive manufacturing can …
Published in International Journal of Crystalline Materials · Vol. 2, Issue 2, 2025 · pp. 16–20 Read article
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A Systematic Review on Factors Contributing to Infertility
Abstract: Infertility is a multifactorial reproductive health condition affecting approximately 10–15% of couples worldwide and continues to represent a major clinical and social challenge. Despite substantial advances in assisted reproductive technologies, diagnostic methods, and therapeutic interventions, many couples still face difficulties in achieving pregnancy. The impact of infertility extends beyond physical health, often leading to emotional distress, social pressure, and financial burdens, especially in societies where parenthood is highly valued. Consequently, …
Published in International Journal of Tropical Medicines · Vol. 3, Issue 1, 2026 · pp. 31–35 Read article
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Predictive Learning Powered by AI and Sophisticated Student Engagement Techniques
Abstract: The contemporary landscape of education has witnessed a paradigm shift in integrating advanced technologies that have revolutionized the learning experience. Innovative methodologies have emerged to address longstanding challenges, such as enhancing student engagement, accurately predicting academic performance, and personalizing the learning journey. However, despite the numerous benefits that technology brings to education, there remains a crucial hurdle - sustaining student motivation and engagement. Traditional teaching methodologies often struggle to generate …
Published in International Journal of Behavioral Sciences · Vol. 3, Issue 1, 2026 · pp. 127–140 Read article
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Bridging the Quality Gap: Analyzing NAAC Accreditation and IQAC’s Role in Higher Education Transformation
Abstract: The role of the National Assessment and Accreditation Council (NAAC) and Internal Quality Assurance Cells (IQAC) in ensuring quality standards in higher education institutions (HEIs) in India has been a subject of extensive research. This review synthesizes existing literature to assess the impact of NAAC accreditation on institutional quality enhancement, transparency, curriculum flexibility, and overall governance. A comparative approach highlights the role of IQAC in implementing continuous quality improvement mechanisms. …
Published in International Journal of Education Sciences · Vol. 2, Issue 2, 2025 · pp. 11–16 Read article
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A Review of Drug Design Techniques Assisted by Computers to Combat Diabetes
Abstract: Diabetes mellitus is a global health concern characterized by chronic hyperglycemia and associated complications. The creation of innovative medicines with enhanced efficacy and safety profiles continues to be a top focus, notwithstanding improvements in treatment. A useful method in drug development, computer-aided drug design (CADD) makes it easier to identify possible therapeutic candidates and optimise lead molecules. An extensive synopsis of CADD tactics used in the fight against diabetes is …
Published in Emerging Trends in Personalized Medicines · Vol. 2, Issue 1, 2025 · pp. 1–10 Read article
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A Decade of Viral Evolution (2015–2025): Emergence, Mutations, and Implications for Global Health
Abstract: Over the past decade (2015-2025), viral evolution has profoundly reshaped the global health landscape, challenging healthcare systems, diagnostic tools, therapeutic strategies, and vaccine efficacy. This review comprehensively analyzes the evolutionary trajectories of major human and zoonotic viruses, with a focus on pandemic-prone, drug-resistant, and emerging pathogens. Viral evolution is driven by diverse molecular mechanisms including high mutation rates, recombination, reassortment, host immune pressure, and antiviral interventions, leading to genetic diversification, …
Published in International Journal of Vaccines · Vol. 2, Issue 2, 2025 · pp. 31–40 Read article
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Carbon Capture Using Polymer Based Membranes - A Green Solution to Climate Change
Abstract: Growing concerns over greenhouse gas emissions have intensified the search for efficient and eco-friendly carbon capture technologies. This study explores the potential of innovative polymer-based membranes as a sustainable approach to controlling CO2 emissions. The paper outlines the fundamental mechanisms of gas transport in membranes, reviews recent advancements in polymer material design, and examines various membrane configurations suited for industrial applications. Special attention is given to newly developed high-performance polymers …
Published in International Journal of Membranes · Vol. 2, Issue 2, 2025 · pp. 13–18 Read article
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Assessment of Differential Global Positioning System (DGPS Technology for Generating Accurate Topographic Maps and Controls: A Case Study of Farin-Lamba to Kwali College Area
Abstract: This study investigates the application of Differential Global Positioning System (DGPS) for topographic mapping and control point establishment in Farin-Lamba to Kwali College Area. The second order Survey controls extension are critical indices for ensuring structural and border control mechanisms in environmental development projects. However, creating these controls using traditional ways presents major obstacles. Most modern techniques are improvements on ancient approaches, which raises the possibility of environmental dangers and …
Published in International Journal of Land · Vol. 2, Issue 1, 2025 · pp. 11–23 Read article