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30 articles for “Deficiency disorders”
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Understanding the Cervical Spine Disorder: A Cross-sectional Survey Study
Abstract: Cervical spine disorders encompass a spectrum of conditions including degenerative spondylosis, disc herniation, traumatic injuries, and myelopathy that impair quality of life through chronic pain, neurological deficits, and functional limitations. Globally, neck pain affects over 200 million individuals, with an age-standardized prevalence of 2666 per 100000 population and an incidence of 816 per 100000 person-years, contributing to significant years lived with disability (YLDs). Economic analyses estimate annual direct healthcare costs …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 15, Issue 3, 2025 · pp. 80–97 Read article
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An Overview of Fanconi Anemia: A Genetic Disorder
Abstract: Fanconi Anemia (FA) is a rare genetic disorder caused by DNA repair defects due to pathogenic variants in one of 21 genes. It is the primary cause of inherited bone marrow failure, marked by pancytopenia. Clinically, Fanconi Anemia (FA) is associated with congenital malformations in multiple systems, resulting in progressive bone marrow failure and heightened cancer risk, especially in the urogenital region and the head and neck. There are approximately …
Published in International Journal of Oncological Nursing and Practices · Vol. 2, Issue 2, 2024 · pp. 19–25 Read article
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A Review on Applications of Artificial Intelligence (AI) in Parkinsons’s Disease Diagnosis and Treatment and Its Future Challenges
Abstract: Parkinson’s disease (PD) is a long-term, progressive neurodegenerative disorder that mainly occurs in people older than 60 years, affecting nearly 1% of this population. It is chiefly marked by the loss of dopaminergic neurons in the substantia nigra, a crucial brain region responsible for controlling motor functions. The resultant dopamine deficiency significantly disrupts motor control, manifesting in clinical symptoms such as tremors, bradykinesia, muscle rigidity, and postural instability. While PD …
Published in Research and Reviews: A Journal of Neuroscience · Vol. 15, Issue 3, 2025 · pp. 1–15 Read article
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Global Burden of Major Depressive Disorder: Prevalence, Diagnosis, and Impact: A Comprehensive review
Abstract: In this review, we will discuss about the major depressive disorders on the basis of neurobiological changes. MDD, a prevalent psychiatric condition, manifests as a complex interplay of genetic, environmental, and physiological factors with a substantial impact on individuals and societies globally. Here the clinical assessment is fully based on diagnosis and the statistical manual for mental disorder, 5th edition (DSM-5). The pathophysiology involves Diagnosis alterations in neurotransmitter systems, dysregulation …
Published in Emerging Trends in Metabolites · Vol. 1, Issue 1, 2024 · pp. 54–62 Read article
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Hearing, Speech, and Language Characteristics in a Case with Hemoglobinopathy Secondary to Beta Thalassemia Intermedia
Abstract: Background: Thalassemia is an inherited disorder characterized by a reduced amount or absence of hemoglobin, the oxygen-carrying protein inside the red blood cell. Thalassemia has its types called alpha and beta-thalassemia. Beta thalassemia is a condition in which there is a reduction or deficit in the synthesis of the beta-globin chain of hemoglobin molecules caused by a mutation in chromosome eleven. Beta thalassemia can be broadly categorized into three main …
Published in Research and Reviews : A Journal of Medical Science and Technology · Vol. 14, Issue 1, 2024 · pp. 1–5 Read article
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Ayurvedic Approach in Case of Irritable Bowel Disease– A Case Study Highlighting the Efficacy and Safety
Abstract: Irritable bowel disease (IBD) is a common psychosomatic disorder that affects the gastrointestinal system, with symptoms that include cramping, abdominal pain, bloating, flatulence, and diarrhea or constipation, or both. If left untreated, it turns into chronic IBS. It can be controlled by adjusting the diet, changing the lifestyle. More severe symptoms include weight loss, diarrhea at night, bleeding from the rectum, anemia due to iron deficiency, unexplained vomiting, and pain …
Published in Research and Reviews : A Journal of Ayurvedic Science, Yoga and Naturopathy · Vol. 11, Issue 2, 2024 · pp. 9–13 Read article
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Calf Mortality in the Tropics: Multidimensional Challenges and Implications for Sustainable Dairy Development
Abstract: Calf mortality remains a significant challenge in tropical dairy farming, posing threats to productivity and sustainability. This review explores the multifactorial factors contributing to calf mortality in the tropics, including environmental stress, infectious diseases, nutritional deficiencies, management practices, genetic factors, and social dynamics. Tropical climates, characterized by extreme temperature variations, humidity, and poor shelter, exacerbate stress and compromise calf health. Infectious diseases, such as bacterial, viral, and parasitic infections, coupled …
Published in Research and Reviews : Journal of Veterinary Science and Technology · Vol. 14, Issue 3, 2025 · pp. 7–23 Read article
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A Comprehensive Review of Nutritional Supplements
Abstract: The role of nutrition and nutraceuticals in human health and disease, covering macronutrients, micronutrients, organic acids, trace and macro minerals, vitamins, and bioactive compounds. It outlines biochemical structures, dietary sources, metabolism, physiological functions, and deficiency states of carbohydrates, proteins and amino acids, and fats. Key organic acids, choline, and taurine are described for their metabolic and digestive roles. The document evaluates dietary supplements, functional foods, nutraceuticals, designer foods, and medicinal …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 17, Issue 1, 2026 · pp. 40–81 Read article
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A Review of Biotechnology Advancements as Key Drivers of Scientific Innovations
Abstract: The rising human challenges have necessitated the quest to find lasting solutions to improve living standards. Challenges in food security in terms of quality and quantity, medical and health issues, energy deficiency and limitations in areas of transportation, domestic and industrial needs, as well as environmental issues are some major areas of application of biotechnology to sustain human existence. This review examines major scientific innovations driven by biotechnology. Biotechnology applied …
Published in Research and Reviews : A Journal of Biotechnology · Vol. 15, Issue 3, 2025 · pp. 22–33 Read article
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Rheumatoid Arthritis and Stem Cell Therapies Perspectives for It
Abstract: Rheumatoid arthritis (RA) is a chronic autoimmune disorder characterized by systemic inflammation, primarily affecting synovial joints, leading to joint destruction and systemic complications. The pathogenesis involves immune system dysregulation, autoantibody production, and enzymatic imbalances. Enzymes, including matrix metalloproteinases (MMPs), serine proteases, and kinases, play crucial roles in these processes. Their dysregulation contributes significantly to disease progression through the imbalance of pro-inflammatory cytokines, oxidative stress, and extracellular matrix (ECM) degradation. MMPs, …
Published in Research and Reviews : A Journal of Biotechnology · Vol. 15, Issue 2, 2025 Read article