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47 articles for “Cognitive impairment”
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Comprehensive Review of Moebius Syndrome: Clinical Landscape, Etiology, and Therapeutic Challenges
Abstract: Moebius syndrome, a rare congenital neuromuscular disorder, presents with non-progressive facial weakness, limited eye abduction, and diverse manifestations affecting cranial nerves. This comprehensive review explores its clinical landscape, emphasizing the need for extensive investigations into its elusive etiology and genetic underpinnings. The estimated prevalence is 1 in 250,000 live births, with sporadic cases prevailing. Initial symptoms, evident from birth, encompass difficulties in sucking, and feeding, and absent facial expressiveness. Beyond …
Published in International Journal of Bioinformatics and Computational Biology · Vol. 2, Issue 1, 2024 · pp. 27–38 Read article
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Early Detection of Alzheimer’s Disease Using Machine Learning Techniques
Abstract: Alzheimer's Disease (AD) is a progressive neurodegenerative condition impacting a large global population. Detecting AD early is critical for timely intervention and effective management. Conventional diagnostic approaches involve cognitive assessments and neuroimaging, which are often lengthy, costly, and prone to human error. In this paper, we propose a novel approach for early detection of AD using machine learning techniques applied to multimodal data, including neuroimaging, cognitive assessments, and biomarkers. Our …
Published in Research and Reviews: A Journal of Neuroscience · Vol. 14, Issue 2, 2024 · pp. 32–43 Read article
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Environmental Pollutants and Biodiversity Loss: Analyzing the Role of Persistent Organic Pollutants in Ecosystem Decline
Abstract: Persistent Organic Pollutants (POPs) significantly impact biodiversity, with various factors influencing their effects on species and ecosystems. Species in poor body condition, like carnivores and predators, are more vulnerable to POPs due to weakened immune systems and reduced detoxification abilities. Dietary habits also affect the accumulation of POPs, as chemicals biomagnify up the food chain. Carnivores accumulate higher concentrations, leading to reproductive failures, hormonal imbalances, and death, while herbivores face …
Published in International Journal of Toxins and Toxics · Vol. 2, Issue 1, 2025 · pp. 9–20 Read article
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Intergenerational Cycle of Malnutrition & Ill Health
Abstract: Malnutrition is a pervasive global issue that significantly undermines the health, productivity, and overall development of individuals, particularly in low-income and developing regions. It affects all age groups but disproportionately impacts young children and women, perpetuating an intergenerational cycle of ill health and poverty. Factors such as economic disparities, lack of education, and entrenched social inequalities exacerbate the prevalence of malnutrition, making it a critical barrier to achieving sustainable development …
Published in Research & Reviews : Journal of Food Science & Technology · Vol. 14, Issue 1, 2025 · pp. 19–25 Read article
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Neurodegeneration and Cognitive Decline: Causes, Consequences, and Treatment Approaches
Abstract: Neurodegenerative diseases gradually destroy nerve cells, often leading to fatal outcomes. The phrase includes a wide range of clinical problems, such as a variety of Neurological conditions include movement disorders, like Parkinson’s disease (PD) and progressive cognitive impairments, with Alzheimer’s disease (AD) being the most common among them. A loss of neurones and synaptic connections, typically in later life, is a prevalent feature of Usually, the onset and development of …
Published in International Journal of Cell Biology and Cellular Functions · Vol. 3, Issue 1, 2025 · pp. 47–59 Read article
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Samelisant, an H3 Receptor Agonist as an Anti-Alzheimer Potential – A Pilot Study on Molecular Docking
Abstract: Neurodegenerative diseases have become more prevalent and about 55 million of the population are affected by dementia globally. One of the most important neurodegenerative diseases is Alzheimer’s disease which is known for its effect on memory and cognitive impairment. Alzheimer’s disease (AD) is an area of intense scientific investigation due to its high prevalence and the lack of a definitive cure. Amyloid precursor protein plays a central role in Alzheimer’s …
Published in International Journal of Brain Sciences · Vol. 3, Issue 1, 2026 · pp. 15–26 Read article
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Relationship between Memory and Modality of Stimulus Presentation
Abstract: Memory is the mental faculty that encodes, stores and retrieves information. Recall is the third stage involved in memory. It is influenced by both internal and external variables including stimulus presentation modality. Researchers in the past have compared recall for words presented across the auditory and visual modality, claiming one to be superior to the other. The present study aimed to compare the recall abilities for visual (pictures) and auditory …
Published in Research and Reviews : Journal of Computational Biology · Vol. 7, Issue 2, 2018 · pp. 42–45 Read article
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A Review on Liability of Mental Health Disorders in HIV Patients
Abstract: Abstract Mental health problems are common among those infected with HIV and also many studies shows that HIV-infected patients have shown higher prevalence rates of psychiatric disorder. Common mental health issues include major depressive disorder , mania, cognitive impairment, psychotic disorders and substance abuse. Mental health problem show its effects on emotions, behavior causing the psychological distress and also decreases the effectiveness of Anti-retroviral treatment in HIV patients. Our literature …
Published in Research and Reviews: A Journal of Neuroscience · Vol. 10, Issue 2, 2020 · pp. 12–16 Read article
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Efficacy of Kalyanaka Ghritam and Sarpagandhadi yoga in Management of Scizophrenia.
Abstract: Clinical trials have shown that antipsychotic drugs alone have limited longterm efficacy. Moreover, they often have adverse side effects including dependency, drowsiness, impaired cognition and memory and sexual dysfunction. The present study was aimed at setting up a standard profile of Kalyanaka Ghrita and Sarpagandhadi yoga which was prepared using pharmacognostically authenticated raw drugs followed by subjecting it to detailed pharmacognostical analysis as per standard protocol.
Published in Research and Reviews: A Journal of Neuroscience · Vol. 12, Issue 1, 2022 · pp. 16–26 Read article
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Iron Deficiency Anemia: From Historical Background to Management—A Review
Abstract: The word anemia comes from the ancient Greek word άναιμία, anaimia, meaning ‘lack of blood’. Simply, anemia means a decrease in the total amount of hemoglobin (Hb) or the number of red blood cells (RBCs). Anemia remains a widespread public health problem with major consequences on human health as well as social and economic development. Globally, the most significant contributor to the onset of anemia is iron deficiency (ID) so …
Published in Research and Reviews: Journal of Oncology and Hematology · Vol. 9, Issue 1, 2020 · pp. 29–40 Read article
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FMR1 Key Biomarker in Fragile X Syndrome- A Comprehensive Review
Abstract: Fragile X Syndrome (FXS) is a complicated neurodevelopmental condition that causes intellectual disabilities, behavioural issues, and a variety of physical symptoms. Central to understanding FXS is the Fragile X Mental Retardation 1 (FMR1) gene, pivotal in the disorder's pathogenesis. This review examines FMR1 as a key biomarker in FXS, drawing on recent research insights. The FMR1 gene, situated on the X chromosome, encodes the fragile X mental retardation protein (FMRP), …
Published in International Journal of Brain Sciences · Vol. 1, Issue 2, 2024 · pp. 8–18 Read article
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Down’s Syndrome (DS): A Genetic Disorder
Abstract: Down’s syndrome (DS) is a chromosomal disorder which occurs due to an error in cell division subsequently leading to an extra 21st chromosome. DS or trisomy 21 is a condition where an individual has 47 chromosomes in each cell instead of 46. It is a multisystem disorder as it affects more than one system of our body. As a consequence, impairments in both cognitive ability and physical growth take place …
Published in Research and Reviews : A Journal of Immunology · Vol. 5, Issue 2, 2015 · pp. 21–26 Read article
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Circadian Regulation of Lipid Peroxidation in the Brain: Linking Ferroptosis to Neurodegenerative Vulnerability
Abstract: The human brain operates through highly coordinated physiological and biochemical processes that regulate cognition, behavior, and neural adaptability. Central to these processes are mechanisms governing brain function, neurophysiology, and neuroplasticity, which are increasingly recognized to be influenced by circadian rhythms. Recent advances in cognitive neuroscience, neuroimaging, and behavioral neuroscience have revealed that disruptions in circadian regulation can significantly impact oxidative balance within the brain, particularly through enhanced lipid peroxidation. Lipid …
Published in International Journal of Brain Sciences · Vol. 3, Issue 2, 2026 · pp. 1–14 Read article
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Paediatric Epilepsy: Current Advances in Diagnosis and Management
Abstract: Paediatric epilepsy is one of the most common chronic neurological disorders of childhood, characterised by recurrent unprovoked seizures resulting from abnormal neuronal activity. Accurate diagnosis is essential and is based on a detailed clinical history, seizure semiology, neurological examination, and electroencephalography (EEG), with neuroimaging such as magnetic resonance imaging (MRI) used to identify structural abnormalities. Classification according to seizure type and underlying aetiology genetic, structural, metabolic, immune, infectious, or unknown—guides …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 16, Issue 1, 2026 · pp. 53–68 Read article
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Unveiling Insights and Strategies for Cognitive Mental Acuity
Abstract: This comprehensive review focuses on the intricate facets of cognition, emphasizing its multifaceted nature rooted in thought, experience and sensory perception. The role of key brain regions, such as the prefrontal cortex, temporal lobes, parietal cortex, occipital cortex and cerebellum, is elucidated in shaping various mental functions. The pathophysiology of cognitive decline is examined, linking specific impairments to damage in distinct brain regions. The study delves into pharmacological and non-pharmacological …
Published in Research and Reviews: A Journal of Neuroscience · Vol. 14, Issue 1, 2024 · pp. 1–10 Read article
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Schizophenia – An Ayurvedic Review and Treatment – A Case study
Abstract: Schizophrenia is a complex, heterogeneous disorder. It is neuro developmental disorder characterized by problems with thinking (cognition),behavior- not focused on goals, negative symptoms, suicidal thoughts This means having a reduced or impaired ability to function normally and having noemotions(notmakingeyecontact,notchangingfacialexpressions,orspeakinginamonotone).Additionally, the person may lose interest in daily activities, withdraw from relationships, or be unable to sustain and reflection often associated with hearing or speech disorders, extreme confusion and associated functional impairments. …
Published in Research and Reviews : A Journal of Ayurvedic Science, Yoga and Naturopathy · Vol. 11, Issue 1, 2024 · pp. 40–48 Read article
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Exploring the Potential of AI-Driven Personalized Learning and Cognitive Interventions for ADHD Management in Indian Children and Adolescents: A Focus on Early Intervention
Abstract: Attention Deficit Hyperactivity Disorder (ADHD) is a prevalent neurodevelopmental condition that significantly impairs attention, executive functioning, and behavioural regulation in children and adolescents. In India, the management of ADHD is particularly challenging due to low public awareness, social stigma, and a critical shortage of specialized mental health services, especially in rural areas. These systemic barriers often lead to delayed diagnoses and limited access to consistent care. However, with the rapid …
Published in International Journal of Brain Sciences · Vol. 2, Issue 2, 2025 · pp. 1–5 Read article
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Yoga and Neural Health: Enhancing Brain Function Through Postural Alignment
Abstract: Correct posture significantly influences neural function and brain health by ensuring optimal alignment of the spine and nervous system. Poor posture disrupts neural communication, impairs blood flow, and affects cerebrospinal fluid (CSF) circulation, leading to adverse effects on cognitive performance, emotional regulation, and overall brain health. This study examines the physiological connection between posture and neural health, emphasizing its impact on cognitive function, mood, and neuroplasticity. Using a mixed-methods approach, …
Published in Recent Trends in Sports · Vol. 2, Issue 1, 2025 · pp. 24–28 Read article
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Molecular Identification of Common Bacterial Infection in Chronic Otitis Media in an Outpatient Department of Tertiary Care Hospital
Abstract: Chronic otitis media (COM) is a chronic inflammation of the mucoperiosteum of the middle ear left which leads to profuse discharge from the ear and hearing impairment that may have a serious long-term effect on language, auditory and cognitive development and on educational progress. In the present study, the prevalence of culture-positive cases of an active mucosal variety of COM was 92.65%. Pseudomonas aeruginosa (41.2%) was the predominant aerobic bacterial …
Published in Research and Reviews : A Journal of Medical Science and Technology · Vol. 8, Issue 1, 2019 · pp. 18–24 Read article
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Music Based Remediation Therapy as an Adjunct to Conventional Physiotherapy Treatment for Primary and Secondary Impairments in Patients with Traumatic Brain Injury and Stroke: A Systematic Review
Abstract: Stroke is a second leading cause of death and major cause of long term disability whereas traumatic brain injury being a disabling health condition. Music therapy is a therapeutic application of music to cognitive, behaviour, sensory and motor dysfunction. To examine the effects of music therapy as an adjunct intervention with conventional treatment versus conventional treatment alone and other therapies on cognition, behaviour, upper extremity function, fine motor skills and …
Published in Research and Reviews: A Journal of Neuroscience · Vol. 6, Issue 1, 2016 · pp. 1–9 Read article