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51 articles for “Bioactive”
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A Review Article on Spice up the Solution of Inflammation Through Phytomedicines
Abstract: Inflammation is a complex, protective immune response essential for healing and combating infection. However, prolonged inflammation is associated with chronic diseases, such as arthritis, cardiovascular disorders, diabetes, and neurodegenerative conditions. Traditional nonsteroidal anti-inflammatory drugs (NSAIDs) and corticosteroids can exhibit adverse effects, particularly with chronic administration. This challenge has encouraged the exploration of natural alternatives. Among various natural anti-inflammatory agents, spices, such as ginger, garlic, turmeric, cardamom, and black pepper have …
Published in Emerging Trends in Metabolites · Vol. 2, Issue 1, 2025 · pp. 1–10 Read article
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Flaxseed-Based Drug Delivery Systems: Advancing Colon Cancer Treatment
Abstract: Flaxseed (Linum usitatissimum) has long been appreciated for its rich nutritional profile, including essential fatty acids (such as α-linolenic acid), plant fibers, and lignans. Recent research has focused on its potential as a novel drug delivery system (DDS) for the treatment of colon cancer. This review explores the bioactive constituents of flaxseed, their pharmacological activities, and innovative approaches to the use of flaxseed extracts in drug delivery for the treatment …
Published in Emerging Trends in Personalized Medicines · Vol. 2, Issue 1, 2025 · pp. 54–59 Read article
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A Comprehensive Review on Neturaceuticals in Alzheimer's and Neurodegenerative Disease an Cognitive Enhancement
Abstract: Neurodegenerative diseases, including Alzheimers disease (AD), Parkinsons disease (PD), and related cognitive disorders, represent a significant and growing public health challenge, particularly in aging populations. Despite advances in pharmacological treatments, therapeutic options for cognitive decline and neurodegeneration remain limited. Recent interest has shifted towards nutraceuticals— bioactive compounds derived from food or natural sources—as promising adjuncts or alternatives in the management of these conditions. This review examines how nutraceuticals can help …
Published in International Journal of Brain Sciences · Vol. 2, Issue 1, 2025 · pp. 1–9 Read article
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Millet Bran: Unveiling Its Potential Health Benefits
Abstract: Millet bran, derived from various millet grains, has emerged as a potent nutritional source, rich in fiber, vitamins, minerals, antioxidants, and omega-3 and omega-6 fatty acids. Its rising popularity is driven by its gluten-free nature, nutrient density, and sustainability. This review aims to explore the potential health benefits of millet bran, focusing on its digestive health, blood sugar control, heart health, antioxidant properties, and fatty acid composition. The Millet brand …
Published in International Journal of Nutritions · Vol. 1, Issue 2, 2024 · pp. 11–19 Read article
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Cannabinoids as Nutritional Supplements: Exploring The Potential Health Benefits and Regulatory Landscape
Abstract: Cannabinoids, the bioactive compounds derived from the Cannabis sativa plant, have garnered increasing interest for their potential role as nutritional supplements. This abstract provides a succinct overview of cannabinoids as nutritional supplements. This review delves into the multifaceted aspects of cannabinoids, particularly their interaction with the endocannabinoid system (ECS) and their potential health benefits. The exploration begins by elucidating the intricate relationship between cannabinoids and the ECS, a vital regulatory …
Published in Emerging Trends in Metabolites · Vol. 1, Issue 1, 2024 · pp. 48–53 Read article
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InSilico Analysis and Homology Modeling of Tetrahydroprotoberberine Oxide involved in the Berberine Biosynthesis
Abstract: Objective: Berberine, a bioactive compound found in various plant species, exhibits diverse pharmacological properties with potential applications in pharmaceutical research. The biosynthesis of berberine involves several enzymatic steps, with (S)-tetrahydroprotoberberine oxidase playing a pivotal role. This study aimed to elucidate the structural and functional characteristics of (S)-tetrahydroprotoberberine oxidase to better understand its role in berberine biosynthesis and its potential biotechnological applications. Methods: Using bioinformatics tools and computational methods, the physicochemical …
Published in Emerging Trends in Metabolites · Vol. 1, Issue 1, 2024 · pp. 7–26 Read article
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Heterocyclic Substituted Flavones: Bridging Natural Products and Medicinal Chemistry
Abstract: Heterocyclic substituted flavones represent a unique and promising class of flavonoid derivatives, gaining significant attention in recent years due to their diverse and enhanced biological activities. These compounds are characterized by the incorporation of heterocyclic moieties such as quinoline, pyridine, thiazole, imidazole, oxazole, and pyrazole into the flavone structure, which significantly alters and often enhances their bioactive properties. This structural modification has made heterocyclic flavones particularly appealing as candidates for …
Published in International Journal of Tropical Medicines · Vol. 2, Issue 1, 2025 · pp. 23–30 Read article
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Secondary Metabolites in Drug Development: Tracing Their Historical and Therapeutic Impact
Abstract: Secondary metabolites, also known as natural products, exhibit a level of structural and chemical diversity unmatched by synthetic small molecule libraries. These compounds, which have evolved to possess drug-like properties, continue to be a primary source for new medications and drug leads. Their discovery has significantly impacted advancements in chemistry, biology, and medicine, influencing drug development and therapeutic strategies throughout history. Derived from primary metabolic pathways such as photosynthesis, glycolysis, …
Published in Emerging Trends in Metabolites · Vol. 1, Issue 2, 2024 · pp. 51–55 Read article
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Pharmacological evaluation of Hepatoprotective activity of Indian medicinal plants Cordia Myxa and Canscora diffusa on wistar albino rats
Abstract: Two plants (Cordia myxa and Canscora diffusa), which were claimed to possess hepatoprotective activity, were selected. The Selected plants were authenticated by an expert botanist. In the current study, herbal extraction involving solvents of decreasing polarity (petroleum ether, ethyl acetate, and hydroalcoholic) was used to extract bioactive compounds from the plants of Cordia Myxa and Canscora diffusa in polyherbal preparations. A phytochemical evaluation was performed, including an acute toxicity study …
Published in International Journal of Tropical Medicines · Vol. 2, Issue 1, 2025 · pp. 31–44 Read article
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Flaxseed and Diabetes Management: A Comprehensive Review of Recent Studies and Potential Mechanisms
Abstract: Diabetes mellitus, a condition characterized by chronic hyperglycemia, has become a significant global health challenge, leading to substantial morbidity and mortality rates. Dietary techniques are crucial for the effective control of diabetes, including both pharmaceutical and non-pharmacological therapies. Flaxseed (Linum usitatissimum) is one of the functional foods that has attracted a lot of interest because of its abundance of bioactive components, including lignans, dietary fiber, and alpha-linolenic acid (ALA). The …
Published in International Journal of Nutritions · Vol. 2, Issue 1, 2025 · pp. 24–32 Read article
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Role of Centella asiatica in Alzheimer’s Disease: A Comprehensive Review
Abstract: Alzheimer's disease (AD) is a progressive neurological illness that causes cognitive decline and memory loss and affects millions of people worldwide. As synthetic medications often prove ineffective or cause severe side effects, natural remedies are gaining attention. This review explores the potential of Centella asiatica, a herb traditionally used in oriental medicine, in the treatment of Alzheimer's disease. Triterpenoids, asiaticoside, and madecassoside are among the bioactive substances found in Centella …
Published in International Journal of Brain Sciences · Vol. 1, Issue 2, 2024 · pp. 1–7 Read article
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The Nutritional Value of Moringa Plant as a Superfood: A Comprehensive Review
Abstract: Moringa oleifera, commonly known as the "miracle tree," has garnered global attention for its rich nutritional profile and diverse medicinal properties. This review article comprehensively explores the nutritional composition and health benefits of Moringa, highlighting its potential as a superfood. The plant is rich in essential nutrients, including proteins, vitamins, minerals, and bioactive compounds, such as flavonoids and phenolic acids. These constituents contribute to its antioxidant, anti-inflammatory, antimicrobial, and anti-cancer …
Published in International Journal of Sustainability · Vol. 1, Issue 2, 2024 · pp. 20–23 Read article
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Unlocking Microbial Potential: Innovations in Natural Product Biosynthesis and Therapeutic Applications
Abstract: MNPs play a pivotal role in diverse fields, spanning medicine, agriculture, and industry. This review paper synthesizes insights from various discussions on microbial natural products, encompassing their sources, bioactive properties, and applications. We explore microbial diversity contributing to natural product synthesis, emphasizing bacteria and fungi as prolific producers. The methods for isolating and characterizing these compounds underscore the interdisciplinary nature of microbial natural product research utilizing various analytical techniques contributing …
Published in International Journal of Fungi · Vol. 2, Issue 1, 2025 · pp. 18–38 Read article
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A Factualistic Study of Phytomedicinal Activity of Curcuma longa (Haldi): Plant That Infuses Life
Abstract: Curcuma longa, commonly known as turmeric, is a plant of remarkable medicinal significance that has been utilized for centuries in traditional medicine and has garnered considerable attention in modern scientific research. This review explores its extensive phytomedicinal potential, focusing on the plant's bioactive compounds, particularly curcumin, which is recognized as the primary agent responsible for its therapeutic properties. Turmeric contains an array of chemical constituents, including curcuminoids, volatile oils, and …
Published in International Journal of Antibiotics · Vol. 2, Issue 2, 2025 · pp. 14–24 Read article
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A Comprehensive review on phytomedicinal activity of chirchita (Achyranthes aspera): an Indian Rural Medicinal Plant
Abstract: Because it is used to treat many types of diseases. Native to India, Achyranthes aspera (Chirchita) has been used in rural medicine for generations.This review explores the phytomedicinal significance of Achyranthes aspera, focusing on its bioactive compounds and the pharmacological activities that support its use in treating various ailments. This plant is a useful tool in traditional and alternative medicine. Because it has anti-inflammatory properties Antioxidants Antibacterial, anticancer and liver …
Published in International Journal of Tropical Medicines · Vol. 2, Issue 1, 2025 · pp. 74–85 Read article
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COSMECEUTICAL: The Intersection Between Beauty and Science
Abstract: The intersection of beauty and science has given rise to the rapidly growing field of cosmeceuticals—products that blend cosmetic and pharmaceutical elements to improve both the appearance and health of the skin. As consumers increasingly seek advanced, evidence-based skincare solutions, the demand for cosmeceuticals has surged. These products typically contain bioactive ingredients that go beyond simple aesthetic enhancement, offering therapeutic benefits backed by scientific research. The article explores the evolving …
Published in Recent Trends in Cosmetics · Vol. 2, Issue 1, 2025 · pp. 17–31 Read article
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Colostrum-Driven Epigenetic Programming in Dairy Cows: A Pathway to Optimal Reproductive Health
Abstract: Colostrum is a vital nutritional source for neonatal calves, providing immune support and essential growth factors. Recent research suggests that colostrum’s impact extends beyond immediate immunological protection, influencing long-term reproductive health through epigenetic modifications. In dairy heifers, early-life exposure to high-quality colostrum may program the developing reproductive system, affecting ovarian function, uterine health, and overall fertility. The components of colostrum, including hormones, growth factors, and bioactive peptides, can induce epigenetic …
Published in Emerging Trends in Metabolites · Vol. 2, Issue 1, 2025 · pp. 35–51 Read article
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Studies on the antioxidant content and antimicrobial activity of cucumber (cucumissativus) peel collected from bagmari, kolkata, west bengal, india
Abstract: Cucumber (Cucumis sativus) is widely consumed across the globe, yet its peels are commonly discarded as waste, despite possessing a wealth of bioactive compounds. Recent studies have highlighted that these peels contain substantial amounts of antioxidants, antibacterial, anti-inflammatory, and anti-carcinogenic properties, making them a promising candidate for value-added applications. In this study, methanolic extracts (80% v/v) of cucumber peels were systematically analyzed to assess their total phenolic content (TPC), total …
Published in Emerging Trends in Metabolites · Vol. 2, Issue 2, 2025 Read article
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Studies on the Antioxidant Content and Antimicrobial Activity of Cucumber (Cucumis sativus) Peels Collected from Bagmari, Kolkata, West Bengal, India
Abstract: Cucumber (Cucumis sativus) is widely consumed across the globe, yet its peels are commonly discarded as waste, despite possessing a wealth of bioactive compounds. Recent studies have highlighted that these peels contain substantial amounts of antioxidants, antibacterial, anti-inflammatory, and anticarcinogenic properties, making them a promising candidate for value-added applications. In this study, methanolic extracts (80% v/v) of cucumber peels were systematically analyzed to assess their total phenolic content (TPC), total …
Published in Emerging Trends in Metabolites · Vol. 2, Issue 2, 2025 · pp. 6–14 Read article
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Postbiotics Unveiled: Mechanistic Insights and Therapeutic Implications in Obesity.
Abstract: The burgeoning global obesity epidemic necessitates innovative therapeutic approaches, and postbiotics, bioactive compounds arising from microbial fermentation, have emerged as promising contenders in reshaping obesity management. This comprehensive review explores the multifaceted mechanisms by which postbiotics impact obesity, from modulating gut microbiota composition to influencing metabolic pathways and enhancing energy expenditure. The exploration of postbiotics is rooted in a deeper understanding of the gut–brain axis and bidirectional communication between gut …
Published in Emerging Trends in Metabolites · Vol. 3, Issue 1, 2026 · pp. 11–28 Read article