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511 articles for “Anti – infective”
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A Review on Five Medicinal Plants having Antimicrobial Activity Available in Bangladesh
Abstract: In the previous years, there has been an augmented growth in the sector of traditional medicine and achieving acceptance not only in developing but also developed countries due to their natural source and minor side effects. A compendious review was presided to accumulate information about medicinal plants having antimicrobial activity available in Bangladesh. Microbial infection possesses several steps including invasion of foreign substances into the host organism, their multiplication and …
Published in Research & Reviews : Journal of Herbal Science · Vol. 10, Issue 1, 2021 · pp. 1–8 Read article
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Investigating the Impact of Viral Infections on Pharmacokinetics and Pharmacodynamics of Antiviral Drugs
Abstract: The emergence and re-emergence of viral infections pose significant challenges to public health, necessitating a comprehensive understanding of how these infections impact the pharmacokinetics and pharmacodynamics of antiviral drugs. This review explores the intricate interactions between viral pathophysiology and the pharmacological effects of antiviral agents. Factors such as viral replication dynamics, host immune responses, and the genetic variability of both viruses and hosts significantly influence drug absorption, distribution, metabolism, and …
Published in International Journal of Virus Studies · Vol. 1, Issue 2, 2024 · pp. 23–30 Read article
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Antibacterial Activities of Crude Extract from Infected Cocoa Against Abscess Forming Bacteria
Abstract: In this study, the antibacterial activity of crude phytoalexin extracted from matured cocoa pod against abscess forming bacteria was investigated. The crude phytolexin was extracted using redistilled dichloromethane after five days of post infection. Different concentrations (50, 100, 150 and 200 mg/ml) of the extract were tested against abscess forming bacteria namely; Escherichia coli, Staphylococcus aureus, Klebsiella Pneumoniae, Pseudomonas aeruginosa and Enterococcus faecium using paper disc and agar diffusion methods. …
Published in Research & Reviews: A Journal of Pharmacognosy · Vol. 2, Issue 3, 2015 · pp. 21–27 Read article
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In vitro Antiviral Chemical Treatment to BBTV-Infected Banana Cultures for Production of Virus-Free Plants
Abstract: Obtaining healthy plants from infected germplasm banana stocks is a major problem. Banana bunchy top virus (BBTV) is the most destructive pathogen for the banana crop. Production of virus-free plants is crucial for cultivation, germplasm conservation and their exchanges. In vitro shoot meristem culture is the most common method for producing disease-free planting material. However, BBTV can multiply with in vitro cultures too. Therefore, for eliminating BBTV, the shoot-tip culture …
Published in Research and Reviews : A Journal of Life Sciences · Vol. 9, Issue 3, 2019 · pp. 28–33 Read article
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Quorum Sensing and Biofilm Dynamics in Pathogens: An Evolving Frontier in Infectious Disease
Abstract: Bacterial and fungal pathogens rarely act as solitary invaders. Instead, they engage in sophisticated chemical communication known as quorum sensing (QS) to coordinate population-wide behaviours and construct structured, multicellular biofilm communities. These biofilms, composed of extracellular polymeric substances, not only facilitate microbial persistence on biotic and abiotic surfaces but also confer remarkable protection against host immune defenses and antimicrobial therapies. QS systems act as central regulators of biofilm dynamics, orchestrating …
Published in International Journal of Pathogens · Vol. 3, Issue 1, 2026 · pp. 18–23 Read article
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Host-Pathogen Coevolution: Implications for Immune Evasion and Pathogen Fitness
Abstract: The interaction between hosts and pathogens represents a continuous evolutionary struggle, shaping both microbial virulence and host immunity. Pathogens employ diverse strategies to evade immune surveillance, ranging from antigenic variation and molecular mimicry to hijacking of host immune checkpoints. Simultaneously, hosts refine innate and adaptive immune mechanisms to counteract infection and limit damage. This reciprocal adaptation, known as host–pathogen coevolution, influences pathogen persistence, transmission, and fitness, while also sculpting immune …
Published in International Journal of Pathogens · Vol. 3, Issue 1, 2026 · pp. 6–10 Read article
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Host Invasion to Immune Evasion: Emerging Concepts in Pathogen Virulence Strategies
Abstract: The interaction between hosts and pathogens represents a continuous evolutionary struggle, shaping both microbial virulence and host immunity. Pathogens employ diverse strategies to evade immune surveillance, ranging from antigenic variation and molecular mimicry to hijacking of host immune checkpoints. Simultaneously, hosts refine innate and adaptive immune mechanisms to counteract infection and limit damage. This reciprocal adaptation, known as host–pathogen coevolution, influences pathogen persistence, transmission, and fitness, while also sculpting immune …
Published in International Journal of Pathogens · Vol. 3, Issue 1, 2026 Read article
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A Chronological Review on Preclinical and Clinical Evaluation of Antimicrobial Sutures
Abstract: Incidence of various infections is increasing with increased number of surgeries. Widespread common surgery procedures are associated with a 1–11% risk of surgical site infections (SSIs) which occur when pathogenic organisms proliferate in surgical wounds, result in impede wound healing, cause separation of the wound edges (dehiscence), and increase the risk of abscess in deeper wound tissues. Surgical site infection increases morbidity and mortality of postoperative patients and require prolonged …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 6, Issue 1, 2016 · pp. 13–16 Read article
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Patient Profile and Antimicrobial Susceptibility Testing of Clinically Isolates In E. coli
Abstract: Escherichia coli, commonly known as E. coli, is a prevalent bacterium capable of causing infections in humans. The development of antimicrobial resistance in E. coli poses a significant public health issue. This study aimed to determine the patient profile and antimicrobial susceptibility patterns of clinically isolated E. coli. A retrospective study was carried out on E. coli samples collected from clinical specimens within a hospital environment. Patient profiles, including age, …
Published in Research and Reviews: A Journal of Microbiology and Virology · Vol. 14, Issue 1, 2024 · pp. 32–47 Read article
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Topical Luliconazole for the Management of Fungal Infections: A Review
Abstract: Luliconazole, an antifungal agent of the imidazole class, possesses a distinctive structure where the imidazole component is fused with the ketene dithioacetate configuration. It exists in its R-enantiomer form, which exhibits greater antifungal efficacy compared to lanoconazole, a compound comprising a racemic blend. Strong action is shown by luliconazole against filamentous fungi, such as dermatophytes. The pharmacokinetic characteristics of dermatophytes, such as Trichophyton rubrum and Microsporum gypseum, help explain why …
Published in Trends in Drug Delivery · Vol. 11, Issue 2, 2024 · pp. 1–6 Read article
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Review of the Antifungal Drug Luconazole for the Treatment of Skin Infections
Abstract: Many U.S. researchers are still working on a broad-spectrum imidazole antifungal called Luliconazole to treat dermatophytic skin and nail infections. The in vitro activity of luliconazole against filamentous fungi, including dermatophytes, is among the highest of any antifungal drug tested to date. The unique molecular characteristics of a 10% solution of Luliconazole make it possible for the drug to quickly reach fungicidal concentrations in the nail unit, allowing it to …
Published in Journal of Catalyst & Catalysis · Vol. 9, Issue 2, 2022 · pp. 13–19 Read article
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Virulence Factors in pathogens :mechanisms of infection & disease progression
Abstract: Pathogens, like bacteria, viruses, fungi, and parasites, have evolved specialized tools – known as virulence factors – that help them infect hosts, escape the immune system, and cause disease. These factors play a key role in determining how severe an infection becomes, how quickly it spreads, and how the body responds. Some pathogens use adhesins to stick to host cells, while others produce toxins that damage tissues or disrupt normal …
Published in International Journal of Pathogens · Vol. 2, Issue 1, 2025 · pp. 6–11 Read article
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Isolation and Characterization of Lantibiotic Producing Lactic Acid Bacteria from Ambali, Aged Mango Pickle Probiotics
Abstract: Each year in the US at least 2 million people are sickened with antibiotic resistant infection. The development of antibiotics was one of the most important advances of medicine. Many bacterial infections (e.g. tuberculosis and infected wounds) that previously had no effective treatment and often killed people became treatable with antibiotics, saving millions of lives. Now, because of the overuse and misuse of antibiotics, bacterial infections that were once easily …
Published in Research & Reviews: A Journal of Bioinformatics · Vol. 3, Issue 3, 2016 · pp. 30–36 Read article
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Phytol—An Unsaturated Alcohol Acting as Vital Biomarker
Abstract: Phytol is a home-grown, phytochemical phytoconstituent which is generally spread in the nature. Phytol is a spread-chain, unsaturated liquor which is available in all plants as a constituent of chlorophyll. Phytol is discovered to be confined from the plant Alternanthera philoxeroides. Phytol is an acyclic alcohol of diterpene regularly accessible in fundamental oils of certain fragrant plants, such as Lantana radula and Cleome serrate. Properties such as cytotoxic, mitigating, against …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 10, Issue 3, 2020 · pp. 6–11 Read article
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Anti-Escherichia coli Potentials of a Novel Chemical Compound 1-(2-hydroxy-1, 2-diphenylethylidene)-3-phenylthiourea
Abstract: Inspiration from the anti-infective excellence (anti-bacterial, anti-fungal, anti-viral, and anti-malarial) of Schiff’s base molecules as well as knowing the rising importance of low-molecular-weight ligands (LMWL), the present research involved the development of novel Schiff’s base compound utilizing very basic laboratory components; 1-phenylthiourea and benzoin using the conventional synthesis technique. The compounds were comprehensively characterized through sophisticated instruments and further screened for anti-microbial activity against pathogenic Escherichia coli (E. coli, MTCC …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 11, Issue 1, 2020 · pp. 9–12 Read article
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Breakthroughs in Biotechnology for the Regulation of Infectious Diseases
Abstract: Infectious diseases have a heavy impact on both public health and the world’s economies. In most diseases, antibiotic resistance has become widespread over time. A variety of diseases comprising pneumonia, tuberculosis, and gonorrhea go through the same evolutionary processes, which include the formation of drug-resistant pathogens in response to selection pressure from medications and their potential extinction when drug use is ceased. Since the occurrence of drug resistance in serious …
Published in Research and Reviews : A Journal of Biotechnology · Vol. 15, Issue 1, 2025 · pp. 1–25 Read article
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Development of a Novel Therapeutic Approach Using RNA Interference for Targeting Viral Genes
Abstract: RNA interference (RNAi) is a ground breaking therapeutic strategy that holds immense promise for targeting viral genes in the treatment of viral infections. This approach leverages the natural gene-silencing mechanisms of RNAi to inhibit viral replication and expression at the molecular level, providing a precise and adaptable method to counteract viral pathogens, including influenza, HIV, and hepatitis viruses. Recent advancements in RNAi technology have enabled the development of highly specific …
Published in International Journal of Virus Studies · Vol. 1, Issue 2, 2024 · pp. 12–22 Read article
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The Effect of Chemical Materials on Bacteria and Fungi
Abstract: Chemical compounds have a significant impact and influence on the effectiveness of some fungal and bacterial organisms, and some of them have been used as chemical antibiotics. It can also be dividedaccording to function. The use of antimicrobial drugs to treat infection is known as antimicrobial chemotherapy while the use of antimicrobial drugs to prevent infection is known as antimicrobial prophylaxis. The main types of antimicrobial agentsare antiseptics (non-specific antimicrobials …
Published in Journal of Catalyst & Catalysis · Vol. 8, Issue 3, 2021 · pp. 1–6 Read article
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Exploring the Potentials of Quercetin and Kaempferol combinations along with Regular Antibiotics for the Effective Management of Methicillin-resistant Staphylococcus aureus (MRSA)
Abstract: The methicillin-resistant S. aureus (MRSA) is a bacterium that offers the challenge to numerous antibiotics which leads to a variety of problems, ranging from skin infections and sepsis to pneumonia. The natural products based management somewhat opened hope towards the betterment of the present era where the combination with currently available medicines has been studied clinically. Antibiotics (cefixime, ceftriaxone, erythromycin, ciprofloxacin, cephradine, methicillin, ampicillin, levofloxacin, and amoxicillin) and flavonoids (quercetin, …
Published in Research and Reviews: A Journal of Microbiology and Virology · Vol. 8, Issue 3, 2018 · pp. 6–9 Read article
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Study of the Antibacterial Activity of Artemisia Absinthium against E. coli bacteria Isolated from Urinary Tract Infections
Abstract: Twenty clinically diagnosed samples were collected using transport medium swabs from the operating room at Al-Amal Specialized Laboratory in Iraq between November 2025 and February 10, 2026. Antibiotic susceptibility testing was performed on the 20 Escherichia coli samples. The results showed a clear difference in the bacterial isolates' response to the tested antibiotics. Imipenem demonstrated the highest inhibition rate, reaching 24.55% (100%), compared to the other antibiotics used in the …
Published in Recent Trends in Infectious Diseases · Vol. 3, Issue 2, 2026 · pp. 17–25 Read article