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406 articles for “strains”
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A molecular docking study and in silico analysis: targeting the marburg virus protein vp35 using active phytocompounds from alchemilla vulgaris
Abstract: Objective: The Marburg Virus Disease (MVD) is an infectious viral disease originating from African Fruit Bats (Rousettus aegyptiacus) that has become the root cause of a fatal hemorrhaging viral fever. As per reports from the WHO, MVD has claimed the lives of millions of people worldwide, with a disease fatality rate ranging from 24% in initial outbreaks to 88% in recent times owing to a difference in viral strains and …
Published in Research and Reviews : Journal of Computational Biology · Vol. 12, Issue 2, 2023 Read article
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Antibacterial Activity of Pongamia pinnata Leaf and Callus Extracts against Microorganisms Causing Periodontal Diseases
Abstract: Some specific microorganisms have been identified as etiologic agents of periodontitis. The main goal of treatment is to control the spread of infection. Depending on the extent of the gum disease, treatment varies. Therapeutic antibiotic along with surgery are the most opted form of treatment. But, due to high costs of antibiotics, the disastrous side effects and emergence of multi drug resistant strains of these pathogenic bacteria, a safe alternative …
Published in Research and Reviews: A Journal of Dentistry · Vol. 3, Issue 2, 2012 · pp. 1–7 Read article
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GeneXpert MTB/RIF Assay (PCR Mycobacterium Tuberculosis): A Revolution in Management of Tuberculosis
Abstract: Background: Workup of pulmonary tuberculosis depends upon sputum microscopy. Sputum microscopy is less sensitive, human resource dependent and time consuming. Sometimes, it lead us to a delay in the diagnosis and may result in the spread of the disease. This seriously disturbs TB control program. There is a need for a more sensitive method. Similarly, early detection of rifampicin resistance is also of utmost importance to prevent MDR strains from …
Published in Research and Reviews : A Journal of Immunology · Vol. 8, Issue 2, 2018 · pp. 8–12 Read article
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Cloning and Expression of LPS-Binding Single Domain Antibody Clones Selected from Phage Display Library of Indian Desert Camel
Abstract: Despite the absence of light chains in their structure, camelid and shark “heavy chain antibodies” (HCAbs) variable domains (designated as VHH) are able to make functional paratopes. The authors have selected lipopolysaccharide (LPS)-binder “single-domain antibodies” (dAb) clones from the previously constructed phage display library of (LPS)-immunized Indian desert camel. This study was undertaken to make available large amounts of some LPS-binder dAb clones by using a suitable expression vector-host system …
Published in Research and Reviews : A Journal of Immunology · Vol. 4, Issue 1, 2014 · pp. 1–7 Read article
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Isolation of Atypical Mycobacteria from an Unusual Site: A Case Study
Abstract: Infections due to atypical mycobacteria have been reported after surgical procedures, liposuction, subcutaneous injections, etc. Here the authors report a case that was operated for umbilical hernia and presented with delayed wound healing, discomfort over site of incision and chronic serous discharge. The exudate from non-healing surgical wound was received in the microbiology laboratory. Ziehl-Neelsen’s stain of the exudate revealed presence of scanty acid fast bacilli which on culture on …
Published in Research and Reviews : A Journal of Immunology · Vol. 4, Issue 1, 2014 · pp. 13–16 Read article
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The Biogenesis, Transmission, Structural and Therapeutics on SARS-CoV-2 (COVID-19) Pandemic: Challenges and Global Perspective
Abstract: The present pandemic situation due to the appearance of COVID-19 has put the world in a miserable condition. About 2.5 million people have been infected with the strain of coronavirus SARS-CoV-2 (Severe Acute Respiratory Syndrome Coronavirus-2) globally. The foremost patient of COVID-19 infection was identified in China in the month of December 2019. Researchers are searching for an effective method to combat this pandemic virus. The investigations have been regulated …
Published in Research and Reviews : A Journal of Immunology · Vol. 11, Issue 1, 2021 · pp. 24–39 Read article
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Neonatal Sepsis: A Study on Isolated Pathogens and Their Susceptibility Pattern at Tertiary Care Hospital in Rural Setting
Abstract: Neonatal sepsis is one of the most important causes of infant mortality and morbidity. In spite of availability of broad spectrum antibiotics, treating sepsis has become a challenge due to emergence of resistant strains from time to time. The present study is aimed at to isolate the organisms causing sepsis in neonates and their antibiotic susceptibility patterns. From April 2013 to June 2014, 167 blood samples were collected from clinically …
Published in Research and Reviews: A Journal of Medicine · Vol. 5, Issue 2, 2015 · pp. 11–15 Read article
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Effect of Heavy Backpack Load and Carrying Duration on Musculoskeletal System: Review
Abstract: Carrying a heavy backpack load can have a detrimental musculoskeletal effect on the health status of school children, army, labor tasks and adults dealing with too heavy working loads. The purpose of this study is to review the literature, to investigate the effect of a collaboration of heavy backpack load on musculoskeletal activities whilst carrying different loads. Mendeley, Cochrane Library, PubMed, Academic Search Complete, Science Direct, and Google Scholar were …
Published in Research and Reviews: A Journal of Medicine · Vol. 10, Issue 1, 2020 · pp. 11–17 Read article
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Development and Applications of a Simple Chalcone- Based Low Molecular Weight Ligand for Treating Nosocomial Infections due to Staphylococcus aureus and Escherichia coli
Abstract: Abstract Inspired from the available biological data of several imperative therapeutic scaffolds in several medicinal chemistry databases, thiophene-containing chalcone compounds were identified and the molecule was designed for treating various nosocomial infections. In one of the recent rational exploration, (E)-3-(4-methoxyphenyl)-1-(thiophen-2-yl)prop-2-en-1-one was synthesized in a single-step reaction, characterized comprehensively by using a few sophisticated spectroscopic instruments such as FT-IR spectroscopy, mass spectroscopy, and 1H-NMR spectroscopy, as well as CHN analyzer, and …
Published in Research and Reviews: A Journal of Medicine · Vol. 10, Issue 2, 2020 · pp. 14–18 Read article
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Prevalence of Lower back pain in a sample population of Musculo-skeletal disorders - Cross sectional community based study
Abstract: Musculoskeletal Disorders (MSD) is a global term for several types of disorders affecting the body’s joints, ligaments, muscles, nerves, tendons and structures that support limbs, neck and back. Low back pain (LBP) is most common musculoskeletal disorder defined as pain and discomfort, localised below the costal margin and above the inferior gluteal folds, with or without referred leg pain.LBP is one of the most common conditions encountered in clinical medicine.LBP …
Published in Research and Reviews: A Journal of Medicine · Vol. 11, Issue 2, 2021 · pp. 38–44 Read article
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Treatment the pediatric rhinitis by CD(Cyclodextrin) garlic suspension
Abstract: Objective: The goal of this study was to identify the effectiveness of vasoconstriction, anti-inflammation and antibiosis of CD garlic powder and to apply this to the treatment of pediatric rhinitis. Materials and Methods: Experimental study objects: Materials: CD garlic powder: we used the CD garlic powder made at Pyongyang Taeun Pharmaceutical Factory. Strain: Escherichia coli O111(ATCC No.25922), Staphylococcus aureus 209-P(ATCC No.25923) purchased from National Microbiological Institute (Pyongyang, DPR Korea). Media: …
Published in Research and Reviews: A Journal of Medicine · Vol. 12, Issue 2, 2022 · pp. 28–33 Read article
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Benzimidic Acid Derivatives as Potential Anti-Escherichia coli Agent for Preventing Nosocomial Infections
Abstract: Based on the global fame of benzimidic acid/benzoic acid derivatives in exhibiting antimicrobial activities against a variety of pathogens (particularly nosocomial infections), two novel compounds (S1 and S2) of benzimidic acid scaffold were rationally designed from a hydrazine derivative and fabricated using the conventional synthesis technique. Through sophisticated instruments, the molecules were comprehensively characterized and investigated for antibacterial activity against pathogenic Escherichia coli strain (MTCC 2961). The novel benzimidic compound …
Published in Research and Reviews : A Journal of Medical Science and Technology · Vol. 9, Issue 1, 2020 · pp. 11–15 Read article
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Antibacterial Potentiality of SourSop Leaf and Fruit Extract: A Review
Abstract: SourSop is scientifically known as Annona muricata Linnaeus, which is a highly potent plant with a wide range of activities especially against cancer. The plant has many health benefits and all its parts have been utilized for treating various diseases. It is also used popularly to make various food items like ice creams and beverages. Lately, it has been explored for its antibacterial and anticancer properties by researchers worldwide. The …
Published in Research and Reviews : A Journal of Medical Science and Technology · Vol. 12, Issue 1, 2024 · pp. 59–64 Read article
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A Study for the Presence of Enterococcal Virulence Factors Gelatinase, Haemolysin among Clinical Isolates in a Tertiary Care Hospital
Abstract: Enterococcus, considered a normal commensal of intestinal tract, is fast emerging pathogen causing serious infection. Despite the increasing importance of Enterococcus as opportunistic pathogens, their virulence factors are still poorly understood. The potential virulence factors of Enterococci include production of enterococcal surface protein (Esp), gelatinase, and haemolysin. Gelatinase- and haemolysin-producing strains of Enterococcus faecalis have been shown to be virulent in animal models of enterococcal infections. This study was undertaken …
Published in Research and Reviews: A Journal of Microbiology and Virology · Vol. 7, Issue 3, 2017 · pp. 14–18 Read article
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Partial Characterization of Crude Lipase from Mutant Soil Fungal Isolate
Abstract: Lipases are cluster of enzymes which cleaves oils and fats. Characterization properties oflipases have been studied in the present investigation because they play an imperative role inseveral industrial applications. The present lipase obtained from soil fungal strain named asEMS5%-60min exhibited optimum activity at pH 7.0 (24.90±0.25 IU/ml/min) and 37ºC (20.28±0.51IU/ml/min). In pH stability profile, the enzyme was found stable in alkaline pH range withhighest activity (13.08±0.07 IU/ml/min) at pH 9.0. …
Published in Research and Reviews: A Journal of Microbiology and Virology · Vol. 8, Issue 3, 2018 · pp. 79–89 Read article
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The Predatory Bacteria, Bdellovibrio and Like Organisms (BALOs): An Emerging Savior for Human Welfare
Abstract: Bdellovibrio and like organisms (BALOs) are capable of killing other Gram negative pathogenic and non-pathogenic bacteria dwelling in a diverse environmental niches such as soil, freshwater and ocean. The predatory nature of BALOs can be a viable alternative to conventional use of antibiotics to treat ocular, periodontal, respiratory and fish pathogen infections since the incessant use develops resistance against them. Unique property such as potential to survive in ecologically hazardous …
Published in Research and Reviews: A Journal of Microbiology and Virology · Vol. 8, Issue 3, 2018 · pp. 19–33 Read article
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Novel Plant Growth Promoting Rhizobacteria from Rhizospheres of Date Palm (Phoenix dactylifera): 16S rRNA Typing and Phylogenetic Analyses Reveal their Distinct Identity
Abstract: AbstractPlant growth-promoting rhizobacteria (PGPR) comprise a large portion of soil microbiome and are essential for the growth of plants as they are capable of exhibiting a range of plant growth promoting biochemical mechanisms. Reports on rhizosphere microflora of date palm tree Phoenix dactylifera are scarce and the rhizomicrobiome of the date palm tree is expected to have microbial members that exhibit features to overcome stress due to varying conditions such …
Published in Research and Reviews: A Journal of Microbiology and Virology · Vol. 9, Issue 1, 2019 · pp. 11–25 Read article
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Lancefield Group of Streptococci Isolated from Dental Plaque Biofilm
Abstract: The purpose of this study was to detect Lancefield group of Streptococci from different disease diagnosed in dental patient visiting the clinic. A total of 500 dental samples of plaque biofilm isolates were tested. Plaque sampling site varied depending on the condition and disease diagnosed in individual subjects. The plaque biofilm samples were collected from subgingival and supragingival including cervical margin of all erupted teeth. Oral diseases such as aphthous …
Published in Research and Reviews: A Journal of Microbiology and Virology · Vol. 9, Issue 1, 2019 · pp. 99–105 Read article
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Prevalence of Multidrug-Resistant Enterobacteriaceae Causing Urinary Tract Infection
Abstract: Urinary tract infections are one of the most common causes of hospital admission, high morbidity and mortality. The most common cause of urinary tract infection is Gram-negative bacteria such as Escherichia coli, Proteus spp., Pseudomonas aeruginosa, Acinetobacter spp., Klebsiella spp., Enterobacter spp., Citrobacter spp. and Gram-positive bacteria such as Enterococcus spp., Staphylococcus aureus and Coagulase-negative Staphylococci. Multidrug-resistant Enterobacteriaceae are emerging worldwide due to high empiric and injudicious use of antibiotics. …
Published in Research and Reviews: A Journal of Microbiology and Virology · Vol. 11, Issue 2, 2021 · pp. 13–18 Read article
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Studies on Biosurfactants from Petroleum Contaminated Soil to Check its Application in Cosmetics
Abstract: Biosurfactant is basically known as surface active molecules, synthesized by different microorganisms. In the present study, biosurfactant producing strains PD1 and PD2 were isolated from the petroleum contaminated site, Vallabh Vidyanagar, Gujarat, India. The isolates were screened by oil displacement and hemolytic methods. The optimization of different parameters was done with the aim of increasing product. Waste substrates were also used to reduce biosurfactant production cost. The surface tension reduction, …
Published in Research and Reviews: A Journal of Microbiology and Virology · Vol. 10, Issue 2, 2020 · pp. 22–28 Read article