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1908 articles for “beclin-1” (ranking capped at the first 2,000 matches — narrow the search to see the rest)
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Optimizing Parameters for Dry Sliding Wear Control in Stir-Cast AA7050/SiC Composites
Abstract: Using a pin-on-disc tribometer, this study examined the dry sliding wear behavior of AA7050/SiC composites. The production of this metal matrix composite was achieved through the stir-casting process, which involved an initial step of melting the AA7050 alloy, followed by the careful introduction of silicon carbide (SiC) particles, stirring to achieve uniform dispersion, and finally, casting the molten mixture. Wear rate (WR) was determined by three operational parameters: SiC reinforcement …
Published in Journal of Polymer & Composites · Vol. 14, Issue 1, 2026 · pp. 1624–1635 Read article
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Turning the Properties of Wastes Paper-Derived Cellulose Nanocrystals for Enhanced Erythromycin Adsorption
Abstract: This study explores the modification, characterization, and adsorption performance of waste paper-derived cellulose nanocrystals (CNCs) for the removal of erythromycin from aqueous solutions. CNCs were modified using organic acid, inorganic acid, and base treatments, and their structural changes were evaluated using FTIR, XRD, and BET analysis. FTIR confirmed the introduction of carboxyl and hydroxyl groups in acid-treated CNCs and deprotonation effects in base-treated CNCs. XRD analysis revealed that organic acid …
Published in Journal of Materials & Metallurgical Engineering · Vol. 16, Issue 1, 2026 · pp. 1–24 Read article
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Synthesis of A Supercapacitor Based on Nanomaterials
Abstract: Demand for various energy storage technologies in electronic and electrical devices continuously goes on increasing. In that context, objective of this research work is to develop and test an electrode of a energy storage module (supercapacitor) using nickel hydroxide and carbon-based nanocomposite materials. Electrochemical performance of electrode is enhanced by optimizing synthesis parameters and designing the electrochemical cell. Conventional and all solid-state supercapacitors are developed with notable electrochemical performance. Pure …
Published in International Journal of Electro-Mechanics and Material Behaviour · Vol. 4, Issue 1, 2026 · pp. 24–39 Read article
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Development of Biodegradable Poly (Lactic-Co-Glycolic Acid) (PLGA) Nanoparticles for Sustained Release of Insulin
Abstract: This research outlines the creation of biodegradable composite nanoparticles made from poly (lactic-co-glycolic acid) (PLGA) designed for the sustained release of insulin. The emphasis is on the interactions between the polymer and the drug at the interface, along with the dynamics of the release matrix. The in vitro release kinetics, surface morphology, encapsulation efficiency, particle size, and polydispersity of insulin-loaded PLGA nanoparticles were analyzed following their production via a double …
Published in Journal of Polymer & Composites · Vol. 14, Issue 1, 2026 · pp. 1690–1699 Read article
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Mechanical Characterization of Prosopis Juliflora Fibre-Reinforced Epoxy Composites for Sustainable Automotive Applications
Abstract: This study investigates the potential of Prosopis juliflora (PJ) fibre as an eco-friendly, economical, and mechanically efficient reinforcement for epoxy-based polymer composites. Composite samples were produced using the compression moulding technique with epoxy-to-fibre weight ratios of 90:10, 85:15, and 80:20. Mechanical tests, including tensile, flexural, impact, and hardness evaluations, were conducted in accordance with relevant ASTM standards. The incorporation of PJ fibre resulted in significant improvements in the mechanical behaviour …
Published in Journal of Polymer & Composites · Vol. 14, Issue 1, 2026 · pp. 1720–1728 Read article
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Cellular Mechanisms of Autophagy in Carcinogenesis: A Narrative Review
Abstract: Autophagy is a highly conserved lysosomal degradation pathway essential for cellular homeostasis, metabolic adaptation, and survival under stress. In the context of carcinogenesis, autophagy exhibits a paradoxical and stage-dependent role. During early tumor development, autophagy acts as a tumor-suppressive mechanism by limiting genomic instability, oxidative stress, and chronic inflammation. Conversely, in established malignancies, cancer cells exploit autophagy to sustain growth, survive hostile tumor microenvironments, and resist anticancer therapies. Increasing evidence …
Published in Research and Reviews: Journal of Oncology and Hematology · Vol. 15, Issue 1, 2026 · pp. 23–28 Read article
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Fabrication of Polydimethylsiloxane Composites with Nickel Nanoparticles: Unification and Current–Voltage Relationship
Abstract: Polydimethylsiloxane (PDMS)–nickel nanoparticle (NiNPs) nanocomposite films were fabricated and systematically investigated to understand their electrical transport behavior through current–voltage (I–V) characterization. Nanocomposite films with varying Ni nanoparticle filler concentrations (14.88 wt%, 15.77 wt%, and 16.65 wt%) were prepared using a solution-mixing and spin-coating technique, followed by controlled thermal curing. The electrical properties of both pristine PDMS and PDMS– NiNPs nanocomposites were examined over a wide voltage range (up to 800 …
Published in Journal of Nanoscience, NanoEngineering & Applications · Vol. 16, Issue 1, 2026 · pp. 22–29 Read article
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Complex Space-Time and the Structure of Relativistic Quantum Theory
Abstract: Relativistic quantum mechanics was developed to reconcile the principles of quantum mechanics with Einstein’s theory of relativity. Despite its success in describing high-energy particles, the theory continues to face unresolved conceptual and mathematical difficulties, particularly in relation to the nature of time, causality, and relativistic consistency. In recent years, the idea of extending space-time into the complex domain has emerged as a useful and potentially meaningful approach to these problems. …
Published in Recent Trends in Mathematics · Vol. 3, Issue 1, 2026 · pp. 22–27 Read article
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Clinical metabolomics: Useful insights, perspectives, and challenges.
Abstract: Metabolomics provides a comprehensive snapshot of smallmolecule intermediates and end products of cellular processes and thereby links genotype, environment, and phenotype in human disease . Over the last decade, advances in liquid chromatography–mass spectrometry (LC–MS) and nuclear magnetic resonance (NMR) spectroscopy have enabled high-throughput profiling of thousands of metabolites from microliter volumes of clinical samples . Clinical metabolomics is now emerging as a tool for disease diagnosis, risk prediction, therapeutic …
Published in Emerging Trends in Metabolites · Vol. 3, Issue 1, 2026 · pp. 29–37 Read article
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Gut Microbial Metabolites in Inflammatory, Metabolic, and Neurologic Disorders.
Abstract: The human gut microbiota transforms dietary and hostderived substrates into a diverse array of metabolites—including shortchain fatty acids (SCFAs), hydrogen sulfide (H₂S), bile acid derivatives, indoles, trimethylamine Noxide (TMAO), branchedchain amino acid (BCAA) derivatives, and lipopolysaccharide (LPS)—that act as key signaling mediators along epithelial, immune, endocrine, and neural axes. These metabolites regulate barrier integrity, energy homeostasis, inflammation, and gut–brain communication and are increasingly implicated in the pathogenesis of inflammatory bowel …
Published in Emerging Trends in Metabolites · Vol. 3, Issue 1, 2026 · pp. 58–64 Read article
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Plant Bioactive Metabolites and Their Role in the Prevention and Control of Dental Diseases and Infections.
Abstract: The oral diseases, including dental caries and periodontitis, affect masses worldwide, and have historically been managed with synthetic antimicrobials that cause deleterious side effects, leading to mounting bacterial resistance. Consequently, contemporary dentistry is rapidly shifting toward phytomedicine using plant bioactive molecules, such as polyphenols, terpenes, anthraquinones (berberin, eugenol, curcumin, catechins, allicin, and azadirachtin. These compounds offer potent antimicrobial, anti-inflammatory, and tissue-regenerative properties that are crucial for preventing and curing dental …
Published in Emerging Trends in Metabolites · Vol. 3, Issue 1, 2026 · pp. 47–66 Read article
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The Mycobiome Frontier – Pre & Post 2020 Status: Integrating Fungal Bioactive Compounds, Probiotics, and Antimicrobial Peptides in Modern Therapeutics and Biotechnology.
Abstract: The fungal kingdom represents an indispensable resource in modern therapeutics and biotechnology, offering a diverse array of bioactive compounds, probiotics, and antimicrobial peptides (AMPs). Functional fungal polysaccharides (FFPs), such as beta-glucans, chitin, and mannans, are centrally involved in modulating the human gut microbiota, providing novel therapeutic avenues for chronic conditions including diabetes, neurodegenerative disorders, and cancer. These compounds act as prebiotics, nourishing beneficial bacteria and enhancing metabolic parameters such as …
Published in International Journal of Fungi · Vol. 3, Issue 1, 2026 · pp. 1–11 Read article
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Seroprevalence and Immunity to Dengue Virus Among Women in Punjab: A Public Health Concern
Abstract: Dengue virus (DENV) infection continues to be a public health concern in Punjab, India, where women are at higher risk because of socioeconomic factors. This cross-sectional study sought to assess the DENV seroprevalence, their neutralizing antibody profiles, and the risk factors associated with DENV among a sample of 1,200 women (aged 18–50 years) in Punjab. Serum samples were processed by IgG/IgM ELISA, and plaque reduction neutralization tests (PRNT90) were done …
Published in Research and Reviews : A Journal of Immunology · Vol. 16, Issue 1, 2026 · pp. 6–10 Read article
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Basalt Fiber, Palm Fiber, and Seashell Powder Reinforced Hybrid Epoxy Composites: A Mechanical Characterization
Abstract: This study investigates epoxy-based composites reinforced with basalt fiber, palm fiber, and seashell powder fabricated via hand lay-up. Mechanical characterization included tensile, flexural, hardness, and impact testing, supported by ANOVA and TOPSIS analyses. The Basalt-Epoxy composite has the highest mechanical strength among the systems under investigation, with a tensile strength of 275 N/mm² and a yield stress of around 215 N/mm². Compared to Palm-Epoxy composite, which has the lowest mechanical …
Published in Journal of Polymer & Composites · Vol. 14, Issue 2, 2026 · pp. 1565–1575 Read article
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Sustainable Development of Carbon–Sisal Reinforced Polyester Composites through Green Nanotechnology
Abstract: This study presents the sustainable development of carbon–sisal fiber reinforced polyester composites enhanced through green nanotechnology for improved mechanical performance and environmental compatibility. The hybrid composites were fabricated using varying fiber ratios - C1 (70% carbon, 30% sisal), C2 (60% carbon, 40% sisal), and C3 (50% carbon, 50% sisal) - with an optimized addition of 1 wt.% nano-silica (SiO2) synthesized via a green sol–gel route. The tensile, flexural, and impact …
Published in Journal of Polymer & Composites · Vol. 14, Issue 2, 2026 · pp. 1179–1194 Read article
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Enhancement of Mechanical Properties in Eutectic Al-Si Alloy Matrix Composites Reinforced with Kyanite and Graphite via Stir Casting
Abstract: The purpose of this work is to enhance the mechanical performance of a eutectic Al–Si alloy by incorporating hard ceramic (kyanite) and soft solid lubricant (graphite) reinforcements using a liquid-state stir casting route. Metal matrix composites were fabricated with kyanite contents of 2, 4, and 6 wt.% and a constant 2.5 wt.% graphite. Their microstructures and mechanical properties were systematically evaluated. The microstructure was examined using optical microscopy and energy …
Published in Journal of Polymer & Composites · Vol. 14, Issue 2, 2026 · pp. 90–100 Read article
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Thermal Dissipation Performance of Metal–Polymer Composite Heat Exchanger for Enhanced Thermal Management in Compact Electric Geysers
Abstract: Most electric geysers these days are made from all-metal stuff, like stainless steel tanks and copper coils for heating, plus mild steel on the outside. Standby heat losses can be 20 to 40 watts, and a 15-litre unit weighs around 6 to 8 kilograms. Manufacturing costs are higher, too. Hard water makes it worse, with limescale building up on the heating elements and cutting thermal conductivity by 10 to 30 …
Published in Journal of Polymer & Composites · Vol. 14, Issue 2, 2026 · pp. 618–651 Read article
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Integrative Structural-Functional Genomics of Fc and Fab: Precision Models for Monoclonal Antibody Stability and Anti-Aggregation Engineering
Abstract: Monoclonal antibodies (mAbs) represent the cornerstone of biotherapeutics, yet aggregation propensity compromises up to 50% of candidates during development, driven by Fab hypervariability and Fc vulnerabilities.(1,2) This review integrates functional genomics from OAS (4B+ sequences)(5) and structural databases (SAbDab: 10K+ structures)(6) with machine learning models achieving R=0.97 for SAP prediction.(11) We dissect biophysical mechanisms, benchmark predictive tools (DeepSP, ESM2), and engineering strategies (YTE, FW mutations) that enhance Tm by 5-10°C …
Published in International Journal of Molecular Biotechnological Research · Vol. 4, Issue 1, 2026 Read article
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Reactivity of Monochlorotetrakis2-Isopropylphenoxoniobium(V), [NbCl(OC6H4CH(CH3)2-2)4] towards Chelating Ligands
Abstract: The niobium(V) complexes with the formula [NbCl(OC₆H₄CH(CH₃)₂-2)₄] were successfully synthesized in high yields through the reaction of niobium pentachloride with four equivalent amounts of 2-isopropylphenol in carbon tetrachloride. The synthesized complexes were characterized and confirmed by elemental analysis, molar conductance measurements, infrared (IR) spectroscopy, ^1H and ^13C NMR spectroscopy, as well as mass spectrometric analysis. The spectroscopic studies have shown these to exhibit dimeric structures bridging through isopropylphenoxo groups. The …
Published in International Journal of Minerals · Vol. 3, Issue 1, 2026 · pp. 37–45 Read article
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Non-Contact Quantification of Swelling-Induced Deformation in Polymer Hydrogels Using Image Analysis
Abstract: Swelling of polymer hydrogels governs transport, mechanics, and functional performance in biomedical systems, yet it is often reported using bulk ratios that conceal spatially heterogeneous deformation and boundary-driven instabilities. This study presents a non-contact image-analysis framework to quantify swelling-induced deformation by tracking shape and boundary evolution from time-lapse imaging. The approach segments the hydrogel region, extracts a sub-pixel refined contour, and computes boundary displacement descriptors including mean and upper-percentile normal …
Published in Journal of Polymer & Composites · Vol. 14, Issue 2, 2026 · pp. 1499–1509 Read article