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1260 articles for “CTLA-4”
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Exploring the Role of Small Dense LDL-C and Paraoxonase-I Activity in Lipid Profile Alterations in Postmenopausal Women: Evidence from a Population-Based Study in Punjab, India
Abstract: Background: After menopause, women face a higher risk of cardiovascular disease (CVD) because hormonal changes impact how their bodies process fats. This study aimed to explore the relationship between small dense LDL cholesterol (sdLDL-C), lipid profile, PON1 levels, thyroid function, CBC parameters, and cardiovascular risk in postmenopausal women (45–60 years) in Punjab, India. sdLDL-C is more atherogenic than larger LDL particles, while PON1, linked to HDL, offers heart protection. Thyroid …
Published in Research and Reviews: A Journal of Health Professions · Vol. 15, Issue 2, 2025 · pp. 45–49 Read article
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Development of Environmentally Sustainable Epoxy Composites with Sunflower Seed Husk Fillers and Study on Thermal and Moisture Properties
Abstract: This study examines the development and characterization of epoxy composites reinforced with sunflower seed husk (SSH) fillers fabricated using the compression molding technique. SSH fillers were categorized into two distinct particle size distributions, namely, 4–53 µm and 79–463 µm, and were incorporated into the epoxy matrix at varying volume fractions ranging from 5% to 20%. The water absorption behavior of the composites was assessed according to ASTM standards, and thermogravimetric …
Published in Journal of Polymer & Composites · Vol. 13, Issue 3, 2025 · pp. 28–37 Read article
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Exploring Psychotropic Trends of Medication Use in Psychiatric Outpatients: An Observational Study at a Tertiary Care Hospital
Abstract: Background: Psychotropic medications are essential in managing a wide range of psychiatric disorders, including depression, anxiety, bipolar disorder, and schizophrenia. Prescribing habits in outpatient clinics can differ a lot depending on things like the patient’s age, background, and medical conditions. Aim: This study aims to explore the trends in psychotropic medication use among psychiatric outpatients at a tertiary care hospital, with a focus on understanding prescribing patterns, demographic factors, and …
Published in Research and Reviews: A Journal of Toxicology · Vol. 15, Issue 2, 2025 · pp. 15–23 Read article
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E-Waste Toxicity and Its Environmental Impact, Challenges, and Solutions for Sustainable Waste Management in India
Abstract: Introduction: E-waste describes any electronic component that is obsolete or no longer functional. The ever-increasing public concern of e-waste in India stems predominantly from the aggressive expansion of the electronics industry along with insufficient recycling and disposal practices. Lead, mercury, and cadmium in e-waste pose serious risks to human health and the environment by polluting air, soil, and water. Informal recycling methods further exacerbate these hazards through unsafe practices. This …
Published in Research and Reviews: A Journal of Toxicology · Vol. 15, Issue 2, 2025 · pp. 1–11 Read article
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A Comprehensive Examination of the Compressive Test Results of Concrete Formulations Modified by The Insertion of Ceramic Powder and High-Density Polyethylene Illustrates Nuanced Changes in the Structural Performance Attributes of the Resultant Composite Materials
Abstract: It is becoming crucial to transition from a traditional, utilization-based society to a sustainable one, resulting of the decline in the natural environment, depletion of natural resources, and decreased capacity for final waste disposal. As the populatio grows, so will the demand for concrete. The major goal of this research is to look at the possible technical benefits of using extruded recycled high-density-polyethylene (HDPE) fibers into structural concrete. The mechanical …
Published in Journal of Polymer & Composites · Vol. 13, Issue 3, 2025 · pp. 193–205 Read article
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Synthesis of Thermal Resistant and Transparent Al2O3 Reinforced Epoxy-Based Composite Coatings
Abstract: This study explores the influence of thermal treatment on the structural, optical, and surface wettability characteristics of epoxy-based composite coatings reinforced with 3 wt.% aluminum oxide (Al₂O₃) nanoparticles. The coatings were synthesized via a dip-coating method on carbon fiber substrates and subjected to controlled thermal treatments at 300 °C, 400 °C, and 500 °C to assess their thermal resilience. X-ray diffraction (XRD) analysis confirmed the structural integrity of the composite …
Published in Journal of Polymer & Composites · Vol. 13, Issue 3, 2025 · pp. 178–183 Read article
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Synthesis, Molecular Docking and Biological Evaluation of Novel Chlorobenzenesulfonamide Analogues of Ibuprofen as Anti-Bacterial, Anti-Diabetic and Anti-Alzheimer Agents
Abstract: In this work, we have synthesized novel chlorobenzensulfonamide tertiary amide based analogues of Ibuprofen (Ibu) and investigated them for their anti-bacterial, anti-diabetic and anti-Alzheimer activities. In the first step, Ibu was converted to amide derivatives by incorporating different aromatic amines. These were further converted into sulfonamide analogues (Sul-Ibu, 1-9) by treating it with p-chlorobenzensulfonyl chloride. Sul-Ibu (1-9) were screened against S. aureus, B. subtilis, S. mutans, E. coli, P. aeruginosa, …
Published in International Journal of Cheminformatics · Vol. 3, Issue 1, 2025 · pp. 41–55 Read article
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Synthesis of Activated Carbon from Corn Cob and Factors Affecting its Adsorption and Desorption Efficiency of Cationic Brilliant Green Dye
Abstract: Extreme dye pollutants released from textile, leather, and pulp industries are becoming a major concern to the water. These pollutants are highly toxic to living things. The major objective of this study was to prepare low-cost and efficient activated carbon from corncob (CCAC) adsorbent through the H2SO4 activation method and characterize its suitability for removing brilliant green dye (BGD) from aqueous solution. The adsorption and desorption efficiency of the prepared …
Published in Journal of Water Pollution & Purification Research · Vol. 12, Issue 3, 2025 · pp. 27–44 Read article
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Enhanced Mechanical and Tribological Performance of Magnesium–Boron Carbide Composites Fabricated via Stir Casting for Lightweight Structural Applications
Abstract: This study investigates the fabrication and evaluation of properties of magnesium (Mg) matrix composites reinforced with boron carbide (B₄C) for lightweight structural applications. Stir casting was employed to incorporate B₄C particles at varying weight fractions (0%, 3%, 6%, and 9%) into the magnesium matrix. The influence of B₄C on density, porosity, hardness, tensile strength, and wear resistance was systematically examined. Theoretical density increased from 1.74 g/cm³ (pure Mg) to 1.88 …
Published in Journal of Polymer & Composites · Vol. 13, Issue 4, 2025 · pp. 29–39 Read article
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Air Pollution and Immune Disorders in Women from Urban Punjab: A Clinical and Epidemiological Study
Abstract: Background: Urban Punjab, particularly cities like Ludhiana, Amritsar, and Jalandhar, experiences some of the highest air pollution levels in India due to industrial activity, vehicular emissions, and agricultural practices. Despite this, gender-specific health impacts—especially related to immune function—remain inadequately studied. Objective of the study is to investigate the relationship between air pollution exposure and immune-related disorders in women residing in urban Punjab. A cross-sectional study was conducted from 2022 to …
Published in International Journal of Environmental Noise and Pollution Control · Vol. 3, Issue 1, 2025 · pp. 36–40 Read article
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Enhancing Concrete Durability and Mechanical Properties for Pavement Quality Concrete (PQC) Roads Using Basalt Fiber Reinforcement
Abstract: Concrete, by nature, is brittle and has a very low tensile capacity, which is a double whammy in transportation infrastructure, such as pavement quality concrete (PQC), for roadways, where we need durability and strength. One such method is the use of basalt fibre, as it is a much better way of enhancing the road runway way performance of concrete. This research studies the impact of the addition of basalt fibres …
Published in Journal of Polymer & Composites · Vol. 13, Issue 4, 2025 · pp. 266–280 Read article
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Polymer-Based Materials in Green and Sustainable Construction
Abstract: The escalating impacts of global warming, driven by greenhouse gas emissions, demand urgent action in the construction sector, which contributes over 40% of global CO₂ emissions. Smart buildings, designed to optimize energy use, water efficiency, and occupant comfort through automation and advanced materials, represent a transformative response to these challenges. The convergence of sustainability and urban development has spotlighted the need for green materials in smart building design. With buildings …
Published in Journal of Polymer & Composites · Vol. 13, Issue 5, 2025 · pp. 42–48 Read article
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Physiological and Anatomical Study of The role of Phytoremediation of Mustard Plant in Reducing Pollutants in Najaf Governorate/Iraq
Abstract: The experiment was conducted in Najaf Governorate / Iraq during the winter of 2023 to determine the types of some heavy metals in Najovernorate and to know the role of phytoremediation of mustard plant in absorbing these heavy metals and the plant's response to these pollutants by measuring some nutrients and heavy metals and studying some anatomical characteristics. Large pots were used in the experiment and distributed after a month …
Published in OmniScience: A Multi-disciplinary Journal · Vol. 15, Issue 3, 2025 Read article
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Investigating The Alkalizing Potential of Chandanasava For Restoring Acid-Base Homeostasis in Renal Tubular Acidosis: A Computational and In Silico Pharmacological Study
Abstract: Chandanasava, a traditional Ayurvedic formulation, is recognized for its potential alkalizing properties, which may help restore acid-base homeostasis in conditions such as renal tubular acidosis (RTA). This study aims to investigate the active components of Chandanasava and their interactions with key renal target proteins, Pendrin and Carbonic Anhydrase II, which are essential for maintaining acid-base balance. An in silico approach was utilized to explore the pharmacological potential of the phytochemicals …
Published in International Journal of Bioinformatics and Computational Biology · Vol. 3, Issue 2, 2025 · pp. 28–52 Read article
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Production And Purification of Amylase Through Bacterial Strain
Abstract: Amylases are important industrial enzymes with use in detergents, brewing, and food processing because of their ability to hydrolyze starch. In this research, the production and optimization of α-amylase from a potato soil isolated bacterium using agro-waste as a carbon source is investigated. The isolate had a hydrolytic zone of 13.33 mm and the highest activity of 545 U/mL under submerged fermentation with 1% starch. Optimum conditions were pH 7.0, …
Published in Research and Reviews : A Journal of Biotechnology · Vol. 15, Issue 2, 2025 · pp. 1–10 Read article
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Dosing Control of Urea in Selective Catalytic Reduction (SCR) to enhance the reduction of Nitrogen oxides
Abstract: Selective Catalytic Reduction (SCR) is an effective aftertreatment technique designed to comply with rigorous emission criteria established by global regulatory authorities for the elimination of nitrogen oxides from exhaust streams. Since NOx and ammonia reagents are poisonous and an excess of either is therefore very undesired, it poses an intriguing control problem, particularly at high conversion. SCR systems must reduce NOx emissions as much as possible and reduce the possibility …
Published in Journal of Polymer & Composites · Vol. 14, Issue 1, 2026 · pp. 110–120 Read article
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Enhancing Delamination Resistance in CFRP Composites through surface Functionalization of Woven carbon Fiber by CuO Nanostructures
Abstract: In order to produce a nanostructured interphase that improves the interfacial interaction with an epoxy resin matrix, copper oxide (CuO) nanostructures were hydrothermally formed onto woven carbon fibers (WCF). Hexagonal CuO nanorods were created using a two-step, seed-assisted solvothermal technique on plain woven carbon fiber. This study investigates the effects of surface modification of carbon fibers by the formation of CuO nanostructures using a hydrothermal technique on the mechanical properties …
Published in Journal of Polymer & Composites · Vol. 13, Issue 5, 2025 · pp. 589–602 Read article
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Role of Inflammatory Markers and Lipid Abnormalities in Glycemic Dysregulation Among Type 2 Diabetics
Abstract: Background: Diabetes mellitus (DM) is a chronic metabolic disorder characterized by systemic inflammation and associated with various complications in multiple organs. Type 2 diabetes mellitus (T2DM) specifically involves insulin resistance, hyperglycemia, and inflammatory responses. This study investigates the levels of various inflammatory markers and their correlation with glycaemic control in T2DM patients. Objective: To evaluate the levels of inflammatory markers (including NLR, PLR, SII, SIRI, CRP, IL-6, TNF-α, TGF-β, MCP-1, …
Published in Emerging Trends in Metabolites · Vol. 2, Issue 2, 2025 Read article
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High-Performance Biodegradable Films from Bamboo Derived Cellulose Nanofibers and Silk Fibroin: Engineering Sustainable Polymer Composites
Abstract: This research presents the advancement of biodegradable composite films from cellulose nanofibers (CNFs) extracted from bamboo and silk fibroin (SF) derived from Bombyx mori cocoons. CNF/SF composites were fabricated in three different compositions—CS10, CS30, and CS50—via aqueous blending and solution casting, followed by ethanol-induced β-sheet stabilization. Mechanical testing confirmed a considerable enhancement in tensile strength from 72 MPa (CS10) to 112 MPa (CS50), while Young’s modulus improved from 2.4 GPa …
Published in Journal of Polymer & Composites · Vol. 13, Issue 4, 2025 · pp. 256–265 Read article
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Harnessing Marine and Agro-Waste Resources: Bioengineered Seaweed Polysaccharide–Coconut Films for Next-Generation Sustainable Packaging
Abstract: The increasing demand for biodegradable alternatives to petroleum-based plastics has led to significant interest in marine biopolymer-based packaging materials. This study focuses on the development of eco-friendly biocomposite films by reinforcing carrageenan, extracted from Kappaphycus alvarezii, with alkali-treated coconut at varying loadings (5%, 10%, and 15% w/w). The films were fabricated via solvent casting and subjected to comprehensive characterization. Mechanical analysis revealed substantial enhancement in tensile strength from 21.3 MPa …
Published in Journal of Polymer & Composites · Vol. 13, Issue 4, 2025 · pp. 217–227 Read article