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571 articles for “therapeutic uses”
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Isolation and Characterization of Glucuronide Compound from Luffa Tuberosa (Roxb.) for Potential Applications in Polymer Chemistry
Abstract: This study explores the isolation process of glucuronide compounds from Luffa tuberosa (Roxb.) using an efficient and cost-effective method. The extracted compound, Gypsogenin-3β-O-β-D-Methyl glucuronide, is characterized using spectroscopic techniques such as IR, NMR, and Mass Spectrometry. The polymeric nature of glucuronide-based compounds and their potential applications in polymer and composite materials are discussed. The findings highlight the suitability of glucuronide derivatives in biomedical, pharmaceutical, and polymeric drug delivery systems. Additionally, …
Published in Journal of Polymer & Composites · Vol. 13, Issue 6, 2025 · pp. 566–572 Read article
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Assessment of Finerenone Safety and Efficacy in Individuals with Type 2 Diabetes and Chronic Kidney Disease
Abstract: Background: In this work, we provide strong evidence for the safety and efficacy of finerenone in people with type 2 diabetes and chronic kidney disease. Our goal is to improve patients' quality of life and general well-being through our research. Aim: Finerenone exhibited a significant decrease in the likelihood of renal and cardiovascular (CV) events in individuals with both type 2 diabetes and chronic kidney disease. This exploratory subgroup analysis …
Published in International Journal of Antibiotics · Vol. 1, Issue 2, 2024 · pp. 06–09 Read article
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Evaluation of Drug Utilization Patterns and Prescription Trends in Patients with Hypothyroidism and Hyperthyroidism in a Tertiary Care Hospital
Abstract: Background: Endocrine disorders affecting the thyroid gland represent some of the most frequently encountered conditions globally, necessitating prolonged therapeutic intervention and vigilant clinical surveillance. The evaluation of Drug utilization patterns (DUE) serves an essential function in examining prescriptive behaviours and promoting appropriate pharmaceutical management. Objective: To evaluate drug utilization patterns, prescribing trends, and rationality of therapy in patients with hypothyroidism and hyperthyroidism. Methods: A prospective, cross-sectional observational investigation was performed …
Published in Research and Reviews: A Journal of Medicine · Vol. 16, Issue 2, 2026 · pp. 1–5 Read article
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Nanomedicine in Combination with Artificial Intelligence (AI): Transforming Cancer Treatment
Abstract: The convergence of nanomedicine and artificial intelligence (AI) holds transformative potential for advancing cancer treatment, particularly in liver cancer. Nanomedicine enables the development of targeted drug delivery systems, enhanced imaging modalities, and precise therapeutic interventions, while AI facilitates data-driven decision-making, personalized treatment plans, and predictive analytics. This synergistic approach can significantly improve the diagnosis, treatment, and monitoring of liver cancer by optimizing the use of nanoparticle-based therapies. AI-powered algorithms can …
Published in Trends in Drug Delivery · Vol. 12, Issue 1, 2025 · pp. 27–30 Read article
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Gene Expression Profiling in Autism Spectrum Disorder: A Microarray Analysis Using Gse42133
Abstract: Autism Spectrum Disorder (ASD) is a diverse neurodevelopmental disorder characterized by difficulties in social interaction, communication impairments, and restricted or repetitive patterns of behavior. Despite its increasing prevalence, the underlying molecular mechanisms remain poorly understood. Advances in transcriptomics offer opportunities to investigate the gene expression changes that may contribute to ASD pathophysiology. In this study, the microarray dataset GSE42133 was analyzed, which comprises gene expression profiles from peripheral blood samples …
Published in Research & Reviews: A Journal of Bioinformatics · Vol. 13, Issue 1, 2026 · pp. 37–48 Read article
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ROLE OF SHODHANA KARMA IN IMPROVING EFFICACY OF RASA DRAVYA
Abstract: Shodhana which literally means purification and converting drugs suitable for further procedure. Shodhana is procedure necessary for every drug before taking it for pharmaceutical and therapeutically purposes. The aim of Shodhana is to remove the physical and chemical properties in the sample of raw drugs. Shodhana is also meant for Marana process of minerals and metals for further internal uses. Shodhana is a process which not only eliminates physical and …
Published in Journal of AYUSH: Ayurveda, Yoga, Unani, Siddha and Homeopathy · Vol. 7, Issue 1, 2018 · pp. 33–36 Read article
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Dental Pulp Stem Cells Derived from Wisdom Teeth as Multitarget Biological Modulators of Alzheimer’s and Parkinson’s Disease: Mechanistic Insight and Translational Perspective
Abstract: Alzheimer’s disease and Parkinson’s disease are chronic, progressive neurodegenerative disorders with complex pathogenic pathways such as neuroinflammation, oxidative stress, mitochondrial dysfunction, synaptic degeneration, and reduced neurotrophic signalling. Despite the large amount of research, the pharmacological treatments in use offer only symptomatic relief and cannot significantly prevent or slow down disease progression sufficiently; new pathogenetic treatment strategies are necessary. In recent years, stem cell-based approaches have gained interest as potential therapeutic …
Published in Research and Reviews: A Journal of Dentistry · Vol. 17, Issue 2, 2026 · pp. 7–28 Read article
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Identification of Secondary Metabolites from Zingiber officinale as Inhibitors for Keap 1-Nrf2 small Molecules through Molecular Docking Techniques
Abstract: Objective: Therapeutic plants aid in treating cancer-based cell signaling pathways and preventing certain risk factors. Zingiber officinale has a variety of anti-inflammatory characteristics also contributing to enhanced immunity, reducing cancer risk and used to target the KEAP NRF2. When overexpressed in response to oxidative stress and DNA damage, elevates the risk of developing multiple cancers. NRF2 cellular sensors, which also control and coordinate their expression aid in defending healthy cells …
Published in International Journal of Bioinformatics and Computational Biology · Vol. 1, Issue 2, 2023 · pp. 35–48 Read article
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Controlled Drug Delivery of Furosemides Using Floating Tablet System
Abstract: The development of gastroretentive drug delivery systems (GRDDS) has gained interest, particularly for drugs like furosemide with narrow absorption windows in the upper gastrointestinal (GI) tract. Furosemide, a commonly used diuretic, faces challenges due to limited bioavailability and rapid elimination, requiring frequent dosing and affecting patient compliance. This review highlights the formulation and evaluation of floating furosemide tablets as an effective strategy to enhance therapeutic efficacy. Floating tablets allow prolonged …
Published in International Journal of Membranes · Vol. 2, Issue 1, 2025 · pp. 23–31 Read article
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Uttarabasti in Female Infertility: A Retrospective Analysis of Clinical Outcomes and Safety Profile
Abstract: Background: Uttarabasti (UB) is a specialized Panchakarma procedure involving intrauterine instillation of medicated Sneha, classically indicated in Yonivyapad and Vandhyatwa. It facilitates targeted local drug delivery, bypassing gastrointestinal metabolism and enabling direct therapeutic action at the uterine level. In Ayurvedic understanding, UB achieves Garbhashaya Shuddhi and Apana Vata Anulomana — the two primary pathological corrections considered essential in Vandhyatwa. Infertility affects an estimated 10–15% of couples globally, with a substantial …
Published in Research and Reviews : A Journal of Ayurvedic Science, Yoga and Naturopathy · Vol. 13, Issue 2, 2026 Read article
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Uttarabasti in Female Infertility: A Retrospective Analysis of Clinical Outcomes and Safety Profile
Abstract: Background: Uttarabasti (UB) is a specialized Panchakarma procedure involving intrauterine instillation of medicated Sneha, classically indicated in Yonivyapad and Vandhyatwa. It facilitates targeted local drug delivery, bypassing gastrointestinal metabolism and enabling direct therapeutic action at the uterine level. In Ayurvedic understanding, UB achieves Garbhashaya Shuddhi and Apana Vata Anulomana — the two primary pathological corrections considered essential in Vandhyatwa. Infertility affects an estimated 10–15% of couples globally, with a substantial …
Published in Research and Reviews : A Journal of Ayurvedic Science, Yoga and Naturopathy · Vol. 13, Issue 2, 2026 · pp. 1–14 Read article
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The Role of Artificial Intelligence in Mental Health: Applications in Neurodegenerative Disorders
Abstract: Artificial intelligence (AI) has significantly changed many aspects of medical care, particularly the early evaluation, therapy, and management of neurodegenerative illnesses like Alzheimer's, disease, Parkinson's diseases, and Huntington's diseases. The current research explores the application of AI in mental health with respect to neurological disorders, especially advancements in cognitive examination, neuroimaging analysis, predictive modeling, and customized therapy modalities. Artificial intelligence (AI) systems have shown enormous potential in detecting minute biomarkers …
Published in Research and Reviews : A Journal of Biotechnology · Vol. 15, Issue 3, 2025 · pp. 34–40 Read article
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The Review of Beetroot Composition and Benefits of Beetroot
Abstract: The genus Beta L. comprises the red beetroot, which is linked to the Betoideae branch of the goosefoot family (Amaranthaceae). Because the tuberous root of the vegetable beetroot (Beta vulgaris L.) contains a large amount of nutrients, including vitamins and minerals as well as substances with physiological activity, including betalain, inorganic nitrates, polyphenols, and folates, it is consumed in every country around the world. Like its relative turnip, the beet …
Published in Research and Reviews : A Journal of Ayurvedic Science, Yoga and Naturopathy · Vol. 12, Issue 3, 2025 · pp. 35–42 Read article
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A Technical Survey on Nanotechnology in Nanorobots
Abstract: Nanotechnology, the manipulation of matter at the atomic and molecular scale, has given rise to a revolutionary frontier: nanorobots – microscopic machines capable of interacting with biological systems and environments with unprecedented precision. This study explores the design, functionality, and application of nanorobots in medicine, environmental remediation, and materials science. By integrating principles from materials engineering, biotechnology, and robotics, nanorobots are engineered to perform tasks such as targeted drug delivery, …
Published in Journal of Nanoscience, NanoEngineering & Applications · Vol. 16, Issue 1, 2026 · pp. 14–21 Read article
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Pf Phosphatidylserine decarboxylase: Molecular modeling and inhibithors prediction
Abstract: Plasmodium falciparum (P.f) is a protozoan parasite responsible for the most severe and deadly form of malaria. The resistance of Pf to last resort antimalarial drugs has been reported, there is an urgent need to identify new therapeutic candidates for drug development. Advancements in bioinformatics technologies provide potential cost and time-effective solutions for predicting therapeutic candidates. Phosphatidylserine decarboxylase (PSD) is a member of the lyase family (more specifically, the carboxy-lyases), …
Published in Research and Reviews : Journal of Computational Biology · Vol. 12, Issue 2, 2023 · pp. 60–78 Read article
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Therapeutic Intervention of Post-traumatic Hemiparesis A Case Report
Abstract: This case report was undertaken to describe the evaluation, management, rehabilitation and education about the post traumatic head injury hemiparesis in a middle-aged woman. The history of traumatic brain injury led to formation of subarachnoid hematoma (SAH) which was treated surgically. The reported onset was sudden with chief complaint of not being able to use her right side of the body, postsurgery. The patient was treated surgically following trauma but …
Published in Research and Reviews: A Journal of Neuroscience · Vol. 3, Issue 1, 2013 · pp. 9–17 Read article
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A Brief Overview of the Removal of Fluoride and Chromium Using Polymer Adsorbents
Abstract: Water tainted with heavy metals are the serious worldwide issues face today because of economic and industrial growth. Even at trace amounts, hexavalent chromium is a significant metal ion pollutant that is highly harmful to humans, animals, plants, and microbes. There are several methods for purifying water, but adsorption is one of the most straightforward, practical, and cost-effective approaches. Chromium is one such significant metal that may be released by …
Published in Journal of Thin Films, Coating Science Technology & Application · Vol. 10, Issue 2, 2023 · pp. 1–14 Read article
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Precision Medicine for Neurofibromatosis Type 1: Progress and Prospects in Drug Discovery
Abstract: Objective: The development of neurofibromas, café-au-lait spots, and other neurological problems are the hallmarks of neurofibromatosis type 1 (NF1), a hereditary disorder. The dearth of efficacious pharmaceutical therapies underscores the need for novel therapeutic approaches, even in the face of clinical variability. Through very accurate prediction of the binding affinity of possible therapeutic drugs with the target protein, the computational technique known as “molecular docking” has become a potent tool …
Published in International Journal of Bioinformatics and Computational Biology · Vol. 2, Issue 1, 2024 · pp. 01–15 Read article
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Role of Carbohydrates and Herbal Plants in the Management of Diabetes Mellitus
Abstract: This extensive review explores the intricate relationship between carbohydrates and diabetes mellitus, integrating historical perspectives, biochemical foundations, and modern therapeutic approaches. The article delves into the chemistry of carbohydrates, elucidating their structural diversity and metabolic significance in relation to diabetes pathophysiology. It traces the evolution of diabetes, understanding from ancient civilizations to contemporary molecular insights, highlighting pivotal discoveries such as insulin’s identification. They critically examined various forms of diabetes, including …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 16, Issue 1, 2025 · pp. 34–60 Read article
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Nanotechnology-Based Cosmeceuticals for Anti-Aging and Skin Regeneration
Abstract: Nanotechnology has transformed the cosmetic industry of the cosmeceuticals by allowing the production of sophisticated delivery systems that improve the stability, penetration, bioavailability, and therapeutic efficacy of active ingredients in cosmetics. The present review identifies the value of nanotechnology-based cosmeceuticals in anti-aging and skin regeneration, with special focus on the recent developments in nanocarrier technologies and their use in dermatology. Many nanocarriers have exhibited great potentials in enhancing delivery of …
Published in Recent Trends in Cosmetics · Vol. 3, Issue 2, 2026 · pp. 33–45 Read article