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763 articles for “drugs”
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Polymer Chemistry in Biomedical Applications: Advances and Innovations
Abstract: Polymers have revolutionized biomedical sciences by playing a crucial role in medical devices, drug delivery systems, and tissue engineering. It is important to note that their unique combination of biocompatibility, mechanical strength, and chemical versatility makes them essential for applications such as implants, prosthetics, and diagnostic tools. Biomedical polymers are categorized into natural types (e.g., collagen, chitosan) and synthetic variants (e.g., polyethylene glycol, polylactic acid), each offering distinct benefits depending …
Published in Journal of Polymer & Composites · Vol. 13, Issue 5, 2025 Read article
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Bedaquiline: An In-Depth Exploration into Its Antitubercular Significance
Abstract: Tuberculosis is still a leading infectious disease and a major threat to public health. Although there has been a slow decrease in the incidence over years, its “hard to kill nature” is responsible of about 2 million deaths in HIV infected individuals annually. Bedaquiline, a Diaryl-Quinoline drug was fast-track approved as an orphan drug to combat drug resistance. It shows potent activity against Mycobacterium tuberculosis by interfering with the production …
Published in Research & Reviews: A Journal of Drug Design & Discovery · Vol. 12, Issue 2, 2025 · pp. 06–14 Read article
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Advances in Biopolymer-Based Surgical Implants: A Polymer Chemistry Perspective
Abstract: Biopolymers have emerged as a promising class of materials for surgical implants due to their biocompatibility, biodegradability, and ability to mimic natural tissue properties. These materials play a crucial role in modern biomedical engineering by reducing adverse immune responses and enhancing tissue integration. This paper explores the role of polymer chemistry in developing biopolymer-based surgical implants, highlighting key polymeric materials. These polymers are making them suitable for diverse biomedical applications. …
Published in Journal of Polymer & Composites · Vol. 13, Issue 6, 2025 · pp. 1–6 Read article
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Targeting Papain-Like Protease of Re-Emerging Coronaviruses
Abstract: Re-emerging Corona viruses (CoVs), including SARS-CoV (S-CoVs), and SARS-CoV-2 (S-CoV-2), continue to pose a global health threat due to their high mutation rates, zoonotic spillover potential, and capacity for immune evasion. The global pandemic of year 2019, caused by S-CoV-2, has highlighted the importance for robust antiviral strategies beyond vaccines and RNA polymerase or main protease inhibitors, which are susceptible to resistance. One promising therapeutic target is the S-CoV-2 papain-like …
Published in Research and Reviews : A Journal of Life Sciences · Vol. 15, Issue 3, 2025 · pp. 46–62 Read article
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Iron Oxide/Chitosan Nanocomposite: Properties and Design for AI Enhanced Immunotherapy and Regenerative Medicine
Abstract: Biopolymers are valuable complex materials. They attract attentions of many scientists, engineers, and medical professionals’ due to their distinguished properties for various applications. In this research, emphasis is given to Fe3O4/Chitosan nanocomposite which has desirable biophysical properties compared to pure Chitosan nanoparticles. Following the green synthesis procedures and characterization methods including thermo gravimetric analysis, AI assisted biomedical application of; Fe3O4/Chitosan nanocomposite is presented. The effect of alkali typically, KOH, in …
Published in International Journal of Cheminformatics · Vol. 3, Issue 2, 2025 · pp. 22–32 Read article
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Novel Strategic Framework for AI-Driven Discovery and Development of Smart and Sustainable Polymers in Healthcare
Abstract: The development of new smart and sustainable polymers is emerging as a priority of new health care innovative development, but event before it may be actualized, the usual culprit is the delay and unproductive execution of the old-fashioned R&D efforts. The current paper proposes a strategic plan which will solve all these shortcomings and speed up the material discovery process by using Artificial Intelligence (AI) and Machine Learning (ML). The …
Published in Journal of Polymer & Composites · Vol. 14, Issue 1, 2026 · pp. 1535–1550 Read article
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Nanomedicine in the Tumor Microenvironment: Physiological Modulation Through Tissue Engineering Approaches
Abstract: The integration of nanomedicine and tissue engineering offers transformative strategies for cancer therapy by directly modulating the physiological processes within the tumor microenvironment (TME). This review emphasizes recent advances in nanomedicine that enable precise drug delivery, controlled release, and real-time monitoring of key physiological parameters influencing tumor progression, angiogenesis, and immune evasion. Tissue-engineered 3D tumor models provide physiologically relevant platforms that better mimic in vivo conditions than traditional 2D cultures, …
Published in Research & Reviews: A Journal of Drug Design & Discovery · Vol. 13, Issue 1, 2026 · pp. 19–31 Read article
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Biodegradable and Natural Fiber-Reinforced Polymer Composites for Antimicrobial Coatings in Biomedical Applications
Abstract: Since they make medical equipment more biocompatible and practical, biomedical polymers are quite crucial for the advancement of medical technologies. One of the most exciting applications for biomedical polymers is their possible use as protective drug coatings for devices. These coatings aim to limit bacterial binding and biofilm growth, two key causes of illnesses acquired after implantation. Scientists are searching for fresh approaches to combat microorganisms as the issue of …
Published in Journal of Polymer & Composites · Vol. 13, Issue 6, 2025 · pp. 392–405 Read article
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Hydrogels: Innovations, Applications, and Future Directions in Biomedical Research
Abstract: iomedical applications, drug delivery, hydrogels, smart hydrogels, tissue engineering
Published in Trends in Drug Delivery · Vol. 12, Issue 3, 2025 · pp. 17–27 Read article
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Immunological Biomarkers and Epidemiological Evaluation of Lymphatic Filariasis Elimination Efforts in Osun State, Nigeria
Abstract: Lymphatic filariasis (LF) remains a neglected tropical disease affecting millions globally, despite extensive elimination efforts. While the interruption of transmission is a key goal, the long-term immunological effects on individuals with existing complications like elephantiasis remain poorly understood. This study assessed the current transmission status of LF and the haematological profiles of infected individuals across selected Local Government Areas (LGAs) in Osun State, Nigeria. A total of 7,388 individuals from …
Published in International Journal of Tropical Medicines · Vol. 3, Issue 1, 2026 · pp. 22–30 Read article
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Nanoparticle Chemistry: The Synthesis, Properties and Applications of Polymer and Macromolecule-Based Nanoparticles and Their Composites
Abstract: Nanoparticles have arisen as a transformative branch of materials in chemistry, owing to their unique physicochemical and biological properties that vary from their bulk materials. Various synthesis techniques, including physical (e.g., laser ablation), chemical (e.g., sol-gel, co-precipitation) and biological (e.g., microbial or plant-mediated) approaches, offer control over particle size, shape and surface characteristics. These methods influence the optical, electronic, catalytic and mechanical properties of nanoparticles. Nanoparticles can exhibit high surface …
Published in Journal of Polymer & Composites · Vol. 14, Issue 1, 2026 · pp. 1236–1247 Read article
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Nanotechnology In Herbal Medicine
Abstract: Herbal medicine has been widely used for centuries as a natural and holistic approach to health care. However, many herbal compounds face challenges such as low solubility, low bioavailability, instability, and the lack of targeted delivery, which affect their efficacy. The integration of nanotechnology into herbal medicine has emerged as a promising strategy to overcome these challenges and enhance the pharmacological potential of plant-derived compounds. Nanocarriers such as liposomes, solid …
Published in Nano Trends – A Journal of Nano Technology & Its Applications · Vol. 28, Issue 1, 2025 · pp. 50–69 Read article
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Impact of HIV on Global Health: A Comprehensive Review of Epidemiology and Interventions
Abstract: H.I.V remains a significant health issue of great concern to the world and with great impact to the individuals and communities on a global scale. This is a comprehensive literature review on the epidemiology of HIV, including both the world prevalence of HIV and the regional variations, especially in sub-Saharan Africa. It discusses the most important modes of transmission including sexual, blood, and vertical transmission and investigates the effectiveness of …
Published in International Journal of Virus Studies · Vol. 3, Issue 1, 2026 · pp. 39–45 Read article
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Biological Membranes: Structure, Function, and Their Roles in Disease Pathophysiology
Abstract: Biological membranes are important structures that control cellular work, signal transmission, transport, and communication. Dysfunction of membranes has been considered in the development of many diseases, such as cancer, neurodegenerative diseases, and infections, with the distortion of lipid composition, protein activity, and cellular connections involved in the pathogenesis of the disease. The damage on membrane can be caused by oxidative stress, genetic mutation, and environmental influence to disrupt cellular homeostasis. …
Published in International Journal of Membranes · Vol. 3, Issue 1, 2026 · pp. 38–46 Read article
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A Technical Survey on Nanotechnology in Nanorobots
Abstract: Nanotechnology, the manipulation of matter at the atomic and molecular scale, has given rise to a revolutionary frontier: nanorobots – microscopic machines capable of interacting with biological systems and environments with unprecedented precision. This study explores the design, functionality, and application of nanorobots in medicine, environmental remediation, and materials science. By integrating principles from materials engineering, biotechnology, and robotics, nanorobots are engineered to perform tasks such as targeted drug delivery, …
Published in Journal of Nanoscience, NanoEngineering & Applications · Vol. 16, Issue 1, 2026 · pp. 14–21 Read article
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Exploring the Intersection of AI Network Pharmacology and Ayurveda: Innovations in Traditional Medicine
Abstract: Integrative frameworks that integrate traditional medicine and modern computer research are increasingly important for advancing evidence-based, individualized healthcare. One interesting strategy is the combination of Ayurveda, network pharmacology, and artificial intelligence (AI). AI expands the capability by allowing for the quick analysis of biomedical big data, the identification of therapeutic trends, and the optimization of treatment plans. Ayurveda, with its long-standing emphasis on individualized care, holistic balance, and natural remedies, …
Published in Journal of AYUSH: Ayurveda, Yoga, Unani, Siddha and Homeopathy · Vol. 14, Issue 3, 2025 · pp. 92–98 Read article
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Polymeric Micelles for Medicinal Plant Solubilization and Delivery of Bioactive Compounds
Abstract: This study involved the design, fabrication, and characterization of polymeric micellar nanocomposites utilizing amphiphilic block copolymers to effectively encapsulate and transport hydrophobic phytoconstituents. The selected bioactive molecule is curcumin, a polyphenol with limited water solubility. A polymeric system known as PEG-PCL was utilized to fabricate core-shell nanostructures by a solvent evaporation-induced self-assembly method. The resulting nanocomposites exhibited homogeneity and colloidal stability, characterized by a zeta potential of −18.7 ± 1.4 …
Published in Journal of Polymer & Composites · Vol. 14, Issue 3, 2026 · pp. 208–219 Read article
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Effect of Skin Barrier Damage on Absorption and Action of Cosmeceuticals
Abstract: The skin acts as a primary defensive barrier protecting the human body against environmental aggressors, microbial invasion, and chemical exposure. The integrity of the skin barrier, particularly the stratum corneum, plays a crucial role in regulating the permeation of substances applied topically. Cosmeceuticals, a hybrid category between cosmetics and pharmaceuticals, are designed to deliver biologically active ingredients into the skin to exert therapeutic or beneficial effects. However, the condition of …
Published in Recent Trends in Cosmetics · Vol. 3, Issue 2, 2026 · pp. 1–19 Read article
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Circadian Regulation of Lipid Peroxidation in the Brain: Linking Ferroptosis to Neurodegenerative Vulnerability
Abstract: The human brain operates through highly coordinated physiological and biochemical processes that regulate cognition, behavior, and neural adaptability. Central to these processes are mechanisms governing brain function, neurophysiology, and neuroplasticity, which are increasingly recognized to be influenced by circadian rhythms. Recent advances in cognitive neuroscience, neuroimaging, and behavioral neuroscience have revealed that disruptions in circadian regulation can significantly impact oxidative balance within the brain, particularly through enhanced lipid peroxidation. Lipid …
Published in International Journal of Brain Sciences · Vol. 3, Issue 2, 2026 · pp. 1–14 Read article
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Biopolymer-Based 3D Composite Scaffolds for Bone Tissue Engineering: Photothermal-Responsive Systems with Controlled Pt (IV) Prodrug Release
Abstract: Biopolymer-based composite scaffolds have attracted significant attention as multifunctional platforms at the intersection of polymer science, regenerative medicine, and cancer nanotherapy. In this study, a dual-functional scaffold was developed for simultaneous osteosarcoma treatment and bone regeneration using poly (L-lactic acid) (PLLA) reinforced with bioactive glass (BG) and integrated with a glutathione-responsive platinum (IV) prodrug system (PDA@Pt). To improve interfacial adhesion, photothermal conversion efficiency, and tumor-specific activation, the Pt (IV) prodrug …
Published in Journal of Polymer & Composites · Vol. 14, Issue 3, 2026 · pp. 351–361 Read article