Search
1466 articles for “MODIS”
-
Advancing Gene Therapy: Next-Generation Viral Vector Engineering for Precision, Safety, and Scalability
Abstract: Gene therapy has emerged as a paradigm-shifting modality for the treatment of genetic disorders, malignancies, and rare diseases through the delivery of therapeutic nucleic acids aimed at correcting or modulating dysfunctional gene expression. Among the various delivery systems, viral vectors including adeno-associated viruses (AAVs), lentiviruses, adenoviruses, retroviruses, and herpes simplex viruses have proven indispensable owing to their high transduction efficiencies and adaptability. This review offers a comprehensive assessment of viral …
Published in International Journal of Virus Studies · Vol. 2, Issue 2, 2025 · pp. 37–55 Read article
-
Pharmaceutical Bead Formulations: A Comprehensive Overview into Advanced Drug Delivery
Abstract: Pharmaceutical beads are a unique and flexible drug delivery vehicle that provides numerous possibilities to control the release of drugs, protect them, and increase their therapeutic performance. These beads make it possible to design several types of therapeutic regimens by incorporating active pharmaceutical ingredients in a polymeric or lipid matrix. This review discusses the bead technology in drug delivery from its inception to its present application, focusing on the most …
Published in Trends in Drug Delivery · Vol. 12, Issue 2, 2025 · pp. 78–100 Read article
-
Limestone Calcined Clay Cement (LC3) as a Sustainable Cementitious Composite for Retrofitting Concrete Structures: A Systematic Review
Abstract: This systematic review evaluates the effectiveness of Limestone Calcined Clay Cement (LC3) as a sustainable material for repairing and retrofitting damaged concrete structures. LC3 is highlighted as a low-carbon alternative to Ordinary Portland Cement (OPC), offering improved strength, bonding, and long-term durability. The review compiles and analyzes data from peer-reviewed experimental studies focusing on LC3’s mechanical performance, interface bonding, and durability parameters. Results consistently show higher bond strength, reduced shrinkage, …
Published in Journal of Polymer & Composites · Vol. 13, Issue 6, 2025 · pp. 163–174 Read article
-
Hybrid Composite Behavior of Concrete-Filled Steel Tube (CFST) Columns: Review of Collapse Mechanisms and Polymer-Based Enhancements
Abstract: Concrete-Filled Steel Tube (CFST) columns are an advanced hybrid composite system where the steel tube's confinement and the concrete core's load capacity work together to improve structural performance. While commonly used in civil engineering, CFSTs can also be understood within the framework of composite materials, similar to polymer- and fiber-reinforced composites, in which interactions between phases determine strength, ductility, and failure modes. This review compiles experimental and numerical research on …
Published in Journal of Polymer & Composites · Vol. 14, Issue 1, 2026 · pp. 78–97 Read article
-
Design and Synthesis of Functionalized Copolymers for Enhanced Interfacial Compatibility in Polymer Matrix Composites
Abstract: Interfacial adhesion between the polymer matrix reinforcing phase affects significantly the mechanical and thermal behavior of polymer composites. The study reports on the design and synthesis of functionalized copolymers in the efforts to establish interfacial compatibility based on chemical design. The reinforcements were functionalized doping polar functional groups such as glycidyl methacrylate and maleic anhydride during free-radical copolymerization to form copolymerizing reactive sites that interacted with the reinforcement surfaces. Confirmation …
Published in Journal of Polymer & Composites · Vol. 14, Issue 2, 2026 · pp. 1404–1418 Read article
-
Solid Acid Catalysts for the Selective Conversion of Biomass to Levulinic Acid
Abstract: Levulinic acid (LA) has emerged as a versatile platform chemical with significant potential for producing renewable fuels like gamma-valerolactone (GVL), biodegradable polymers, and fine chemicals from biomass (both terrestrial and marine which ae rich in carbohydrate). The selective conversion of biomass-derived carbohydrates to LA requires efficient catalytic systems that can overcome the recalcitrance of the biomass, namely the stiff-necked structural integrity of cellulose and the kind of strong interactions between …
Published in Journal of Catalyst & Catalysis · Vol. 13, Issue 1, 2026 · pp. 23–35 Read article
-
Plant-Drive Natural Filler Filled Polypropylene Composites: Effects of Filler Treatment, Filler Content and Nanoclay on Properties
Abstract: In this study, PP was blended with nanoclay at three different loadings of 1, 3, and 5 wt%, while maleated polypropylene (PPM) was added at 5 wt%. The results showed that PP nanocomposites prepared at 5% PPM and 3% nanoclay showed optimum mechanical performance. In this research, untreated and chemically treated peanut shell flour (PSF) reinforced PP nanocomposites were prepared at four different loadings of 10, 20, 30, and 40 …
Published in Journal of Catalyst & Catalysis · Vol. 9, Issue 2, 2022 · pp. 1–12 Read article
-
A Study on Soil Stabilization using Cement and Plastic Fibres
Abstract: Soils pose problems to civil engineers in general and to geotechnical engineers in particular. They cause damage to structure founded in them because of their potential to react to changes in moisture regime. Soil stabilization is the process of altering some soil properties by different methods, mechanical or chemical in order to produce an improvement soil material which has all the desired engineering properties. In the present work, an attempt …
Published in Journal of Geotechnical Engineering · Vol. 4, Issue 2, 2017 · pp. 1–8 Read article
-
Effect of Surface Pore Filling and Adhesive Joining on Energy Absorption of Closed Cell Aluminum Foam
Abstract: The joining of aluminum foam is explored in this paper. Foam specimens were sectioned and joined with commercially available adhesive and tested for its energy absorption capability against a normal foam specimen. There was a decrease in the plateau stress but the decrease is not significant. The effect of surface pore filling by the adhesive was also realized. It was found that the adhesive in the surface cells introduces constraints …
Published in Journal of Materials & Metallurgical Engineering · Vol. 2, Issue 1-3, 2012 · pp. 117–124 Read article
-
Preparation and Characterization of a Novel Lignocellulosic Fiber from Calotropis gigantea Stem Fiber for Thermoplastic Composites
Abstract: In the current article, Calotropis gigantea fiber mat (CGM)/thermoplastic polypropylene (PP) strengthened non-woven unidirectional composites were successfully manufactured by hot compression molding using the film piling method. Micromechanical and physicomechanical properties such as tensile, flexural, compressive, impact properties, thickness, swelling, and water absorption of CGM/PP composites were evaluated for the effects of CGF composition, mercerization of CGF as well as the inclusion of two types of coupling agents (vinyltriethoxysilane and …
Published in Journal of Materials & Metallurgical Engineering · Vol. 12, Issue 1, 2022 · pp. 15–33 Read article
-
Electrochemical Exfoliation of Graphene Oxide (GO) and Thermally Reduced Graphene Oxide (TrGO) Using Ecofriendly Reducing Agent as Cow Urine
Abstract: The Graphene oxide (GO), the reduced form of GO i.e. (rGO) with thermally reduced graphene oxide (TrGO), have concerned significant interest in various fields with their exceptional properties. We investigate the electrochemical exfoliation processes of GO and rGO to understand their structural and electrochemical behavior of GO and TrGO through various characterization techniques. The electrochemical exfoliation method offers a versatile and scalable approach for the mass fabrication of the materials …
Published in Journal of Polymer & Composites · Vol. 12, Issue 1, 2024 · pp. 89–100 Read article
-
Influence of Polymer Additives on Physical Properties of Asphalt Concrete under Marshal, Flexure and Compressive Stresses
Abstract: AbstractThe polymer modified asphalt cement is used today to reduce early pavement distress and extend service life by enhancing adhesion, cohesion, and elasticity. This work studies the impact of polymer additives (SBS, LDPE, and rubber) to asphalt cement on the physical properties of asphalt concrete subjected to compression and flexure stresses, and Marshal volumetric properties. Asphalt concrete cylindrical specimens of 101.6 mm diameter and 127 mm height for compressive strength …
Published in Trends in Transport Engineering and Applications · Vol. 4, Issue 3, 2017 · pp. 8–17 Read article
-
Relationship of Adolescents with Family and Impact of Family Composition on their Decision Making
Abstract: Adolescence is portrayed by huge mental, intellectual and socio emotional growth. With the development of teenage years, the measure of time went through with guardians normally drops while time went through with associates escalates impressively. In any case, guardians keep on assuming a key job in improving their undeveloped behaviour. Adolescent parent connection substantially affects intellectual, social and sensitive conduct. Protected connection with adolescents is related with less involvement in …
Published in E-Commerce for Future & Trends · Vol. 6, Issue 1, 2019 · pp. 37–46 Read article
-
The Customized ZigBee Stack: Mathematical Modelling
Abstract: Abstract There are different protocols for realising WPAN. ZigBee protocol supports high node density, long range and robust communication and hence chosen for experimenting in WPAN. ZigBee protocol may not be adequate to bring all the consumer electronic devices under WPAN and control them as the devices may use different protocols. ZigBee stack is taken as base, it is modified to incorporate the features of common communication protocol so as …
Published in Recent Trends in Electronics Communication Systems · Vol. 3, Issue 3, 2016 · pp. 7–14 Read article
-
Strength Analysis of Topside Supports on FPSO Hull
Abstract: AbstractThis paper is performed to determine strength and endurance capacity of topside supports and underlying hull structure on Floating Production Storage Offloading (FPSO) platform. Support stools shall be installed on every intersection between longitudinal bulkheads and transverse frames. Strictly, the analysis is relevant to topside supports and hull structure in the mid-ship area away from the moon-pool, but modification of the results to be representative for the moon-pool area is …
Published in Journal of Offshore Structure and Technology · Vol. 5, Issue 2, 2018 · pp. 22–38 Read article
-
Ferrocenium Ion Encapsulated Montmorillonite Clay as a Voltammetric Sensor for Distinguishing Amino Acids Glycine and Alanine
Abstract: Detection and determination of small bio-molecules and metal ions are of great importance for diagnosis of a number of diseases and understanding environmental pollution leading to extensive research on development of sensors. Among different sensors, electrochemical sensors are unique because of simplicity, low cost, easy maintenance and easy in vivo applications. Voltammetric sensor, one of the major constituents of electrochemical sensors, is essentially a surface modified working electrode (WE). The …
Published in Journal of Modern Chemistry & Chemical Technology · Vol. 9, Issue 1, 2018 · pp. 8–11 Read article
-
Natural Antibodies Against Enteromicrobes and their Toxins for the Treatment of Rheumatoid Arthritis
Abstract: Autoimmune diseases (ADs) are thought to be brought on by the host immune system accidentally attacking and destroying its own tissue. “Molecular mimicry,” which asserts that antibodies against an infectious agent cross-react with a self-antigen possessing an identical or similar antigenic epitope, is a generally recognised theory to explain the pathogenic mechanism of ADs. This theory, however, was probably developed using false antibody assay data that was heavily impacted by …
Published in Research and Reviews : A Journal of Life Sciences · Vol. 12, Issue 3, 2022 · pp. 1–12 Read article
-
Patents on Gastroretentive Drug Delivery System: An Overview
Abstract: Background: Conventional oral dosage forms have poor bioavailability and recurrent dosing of the drug is needed to maintain the effective therapeutic concentration in the body. It may lead to poor patient compliance and fluctuations in the plasma level of drug especially in the chronic diseases and disorders. Origin: In outlook of this, to enhance the efficiency and bioavailability of the drug, gastroretentive drug delivery system is developed which can prolong …
Published in Trends in Drug Delivery · Vol. 8, Issue 1, 2023 · pp. 22–30 Read article
-
Anatomization On Controlled Drug Delivery System
Abstract: Modern target-perception technologies have led to the development of successful controlled drug delivery systems. The process of administering a medication so that it is clinically effective in either people or animals is known as drug supply. Several of the earliest controlled-release systems aimed to achieve a delivery profile that would result in a high drug level in the blood for an extended length of time. When using conventional medication delivery …
Published in Trends in Drug Delivery · Vol. 10, Issue 3, 2023 · pp. 24–32 Read article
-
Environmental implications of Chitosan nanostructures.
Abstract: Chitosan (CS), as a biopolymer, has unrivalled chemical and mechanical modification capabilities to develop novel characteristics, functions, and applications, particularly in the manufacture of cutting-edge membrane adsorbents. Membrane adsorbents utilizing carbon starch (CS) have emerged as a viable and efficient engineering instrument for eliminating diverse pollutants from aquatic settings, including heavy metals and dyes. To date, much study has been directed towards improving the adsorptive characteristics, permeability, physicochemical stability, and …
Published in International Journal of Antibiotics · Vol. 1, Issue 1, 2024 · pp. 42–58 Read article