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1907 articles for “Human epidermal growth factor receptors (HER-2)” (ranking capped at the first 2,000 matches — narrow the search to see the rest)
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Molecular Docking and Pharmacokinetic Profiling of the Phytocompounds of Jatropha curcas as Antagonist for Salmonella typhi
Abstract: Background: Typhoid is an infection caused by the Gram-negative bacterium, Salmonella enterica serovar typhi. The study assessed the potential use of Jatropha curcas as a typhoid fever therapy alternative to traditional medications. The ability to uncover novel drug indications for currently available medications using in silico methods has increased thanks to the wealth of pharmacological and biological knowledge that is available. Objective: In this study, we assessed the potential inhibitory …
Published in International Journal of Cell Biology and Cellular Functions · Vol. 1, Issue 1, 2023 · pp. 67–81 Read article
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Bioactive Compounds in Ethanolic Extract of Strychnos innocua Root Using Gas Chromatography and Mass Spectrometry (GC-MS)
Abstract: Medicinal plants are of great relevance with endless pharmaceutical and therapeutic properties. They are source of wide array of secondary metabolites or bioactive compounds/phytochemicals (phenols, alkaloids, flavonoids, terpenoids, tannins, steroids and saponins) which can discharge numerous biological functions (antimicrobial, antioxidant, antiviral, antifungal, anti-fibrotic, immune-modulatory, cytotoxic, antipyretic, antitumor, antihelminthic, antiprotozoal, antibacterial, and so on). The use of gas chromatography and mass spectrometry analysis in identifying the bioactive compounds in the ethanolic …
Published in International Journal of Biochemistry and Biomolecule Research · Vol. 1, Issue 1, 2023 · pp. 9–14 Read article
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Multifactorial Diseases Becoming the Epigenetic Factor for the Genz
Abstract: This comprehensive paper investigates the complex interplay between multifactorial diseases, particularly obesity and cardiovascular disease (CVD), and their relationship with epigenetic mechanisms, highlighting the transgenerational implications of these interactions. The multifaceted nature of obesity and CVD, involving genetic predisposition, environmental influences, and epigenetic modifications, underscores the intricate pathways contributing to disease susceptibility and progression. Drawing upon a synthesis of diverse research findings, the paper elucidates the critical role of genetic …
Published in International Journal of Genetic Modifications and Recombinations · Vol. 2, Issue 1, 2024 · pp. 16–22 Read article
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Complications with Malware Identification in IoT and an Overview of Artificial Immune Approaches
Abstract: An immunity is facilitated by lymphocyte T&B-cells; that possess a wide range of T&B-cell; receptors, respectively. These cells can identify and react to pathogens and diseased cells by presenting peptide antigens by means of significant histocompatibility complexes (MHCs). The amount of data on the repertoire of adaptive immune receptors has increased dramatically in recent years because to advancements in deep sequencing. Furthermore, the presentation of peptides with MHC has been …
Published in Research and Reviews : A Journal of Immunology · Vol. 14, Issue 1, 2024 · pp. 54–62 Read article
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Monitoring eddy current density fluctuation and power management in doped Al 2 O 3
Abstract: Al2O3 nanowire presents fascinating electrical properties which span from insulating (dielectric) to superconducting. A model is designed to describe the Phenomenon of eddy electric current and eddy current density fluctuation. Ohmic type theorem is developed using the modified Green – Kubo theorem. With little modification Green-Kubo theorem is incorporated to explain the relationship between eddy current density, electric field, and electric conductivity. Then factor contributing eddy current density fluctuations are …
Published in Nano Trends – A Journal of Nano Technology & Its Applications · Vol. 26, Issue 1, 2024 · pp. 35–45 Read article
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Rise of Python: Analyzing Its Dominance in 2023 Programming Trends
Abstract: The study is on how Python rose as a leading programming language in 2023 and what are the top reasons of this ubiquitous utilization among industries. The Python programming language has been a go-to choice for both beginners and developers alike, courtesy of its versatility in working over various domains like Data Science, Machine Learning Web Development Automation etc. By having a vast library and framework ecosystem, supported by popular …
Published in Recent Trends in Parallel Computing · Vol. 11, Issue 2, 2024 · pp. 43–47 Read article
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Comparative Impact of Yoga Practice on Lifestyle in Public and Private Sector Professionals
Abstract: Yoga has become completely embedded in our lifestyle. Without yoga, it has become very difficult to stay healthy. Along with sports, yoga is also very important for human life. It keeps us in shape, active, and intellectually and socially rejuvenated. They impart discipline and coordination skills to us. Our camaraderie and brotherhood are also fostered via yoga and sports. Furthermore, it is crucial for both the physical and mental growth …
Published in Recent Trends in Sports · Vol. 1, Issue 1, 2024 · pp. 11–15 Read article
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Renewable Solar Energy Prediction in India : 2025-2030
Abstract: As India endeavors to realize its objective of achieving 500 GW of renewable energy capacity by the year 2030, the precise forecasting of solar power generation is rendered increasingly essential. This scholarly article conducts a comprehensive review of the utilization of machine learning (ML) methodologies in the prediction of solar energy across diverse Indian states, underscoring their potential to address the complexities associated with the variability of solar irradiance. Conventional …
Published in Journal of Power Electronics and Power Systems · Vol. 14, Issue 3, 2024 · pp. 41–46 Read article
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Application-based Effective Curriculum Design and Development for Employability
Abstract: Employability is becoming a major objective of education today. Every institution is striving to make their students employable. This paper mainly focuses on the theme of outcome-based education’s “effective curriculum design and development” and its present significance. We propose to have a fine blend of Fundamentals and factors in the curriculum design. Considering these factors of the novel approach, a model employability curriculum has been proposed and compared. A case …
Published in Journal of Software Engineering Tools & Technology Trends · Vol. 11, Issue 3, 2024 · pp. 11–17 Read article
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A Review Article on the Human Blood Groups in Relation to Healthy Longevity
Abstract: After significant discovery of the ABO blood groups of human beings by Karl Landsteiner, a number of works have been carried out on different types of blood groups like MN type, Q types, etc. and in the same time, number of researches were also carried regarding different aspects of blood groups like its genetic analysis, its inheritance, its role in paternity test, its role in blood transfusion and general physiology …
Published in Research and Reviews : A Journal of Immunology · Vol. 14, Issue 3, 2024 · pp. 1–5 Read article
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Design of a Water-Cooling System for the Inside Roof of 20t Electric Arc Furnace for Oxygen Blow Decarburization Using CFD Analysis
Abstract: An electric arc furnace (EAF) roof usually works at high temperature for a long time, undergoes not only heat radiations from electric arc, molten metal, and lining of high temperature, but also is washed and affected by chemical erosion due to high temperature and gas flow. In addition, it might be eroded by slag with high temperature. In， inside roof of EAF is more severely affected by heat load than …
Published in Journal of Thermal Engineering and Applications · Vol. 11, Issue 3, 2024 · pp. 11–17 Read article
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Impact of Phosphorus Application Rates on Yield and Yield Components of Common Bean (Phaseolus vulgaris L.) Varieties in Relation to Water Resources at Yabello, Southern Oromia, Ethiopia
Abstract: Common bean is a key legume crop with significant economic importance in Ethiopia, particularly in the southern region of Oromia. One of the primary constraints to common bean productivity in this region is the issue of soil fertility, which is exacerbated by water scarcity. This study was conducted to assess the impact of phosphorus (P) fertilizer rates on common bean growth and yield, as well as to identify sustainable management …
Published in Journal of Water Resource Engineering and Management · Vol. 11, Issue 3, 2024 · pp. 20–31 Read article
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Harnessing Ethylene and Brassinosteroids for Enhanced Agricultural Productivity and Food Quality
Abstract: This study provides a comprehensive review of the roles of ethylene and brassinosteroids, two vital hormonal regulators in plants, focusing on their impact on fruit ripening, stress responses, and overall plant growth. Ethylene, a gaseous plant hormone, is recognized as a key regulator in various physiological processes, particularly in the maturation of fruits. Its involvement in the ripening process has profound implications for agricultural practices, as it directly influences the …
Published in International Journal of Trends in Horticulture · Vol. 1, Issue 2, 2024 · pp. 29–32 Read article
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Nanocomposites of Polyethylene-Closite 20A: Preparation and Characteristics
Abstract: Low-density polyethylene/closite 20A nanocomposites with different organoclay contents were made in the current study by a melt mixing technique with two different compatibilizers of varying contents: low molecular weight oxidized polyethylene and low molecular weight trimethoxysilyl modified polybutadiene. The inclusion of compatibilizers and concentrations of organoclay were analyzed in relation to the mechanical and thermal properties of the nanocomposites. The dispersibility of the silicate clay in the nanocomposites was investigated …
Published in Journal of Nanoscience, NanoEngineering & Applications · Vol. 15, Issue 1, 2025 · pp. 01–12 Read article
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Marine-Derived Pharmaceuticals: Unlocking the Ocean's Potential for Human Health
Abstract: The ocean, covering 70% of the Earth’s surface, is a rich source of unique bioactive compounds with potential therapeutic applications. This review aims to highlight the significance of marine-derived pharmaceuticals in human health, focusing on clinically approved and commercially available medications. The review covers various marine-derived compounds, their structural features, modes of action, and applications in treating diseases, such as cancer, diabetes, and neurodegenerative disorders. The review identifies several marine-derived …
Published in Research & Reviews: A Journal of Pharmacognosy · Vol. 12, Issue 1, 2025 · pp. 1–12 Read article
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Review on Clinical Safety and Efficacy of Giant Calotropis in the 21st Century
Abstract: Calotropis gigantea, a highly valued plant in traditional Indian pharmacology, has emerged as a promising candidate for therapeutic innovation. This review delves into the clinical safety and efficacy of C. gigantea in the 21st century, examining its historical use, phytochemical composition, and pharmacological properties. While traditional medicine has long utilized C. gigantea for various ailments, modern research has sought to validate these claims through scientific investigation. This review critically analyzes …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 15, Issue 1, 2025 · pp. 26–34 Read article
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A Research Study on Cognitive Health Benefits of Nicotine to the Human Body
Abstract: Background: Nicotine has been primarily known for its addictive properties and associated health risks, particularly in tobacco products. However, recent research has highlighted nicotine’s potential cognitive health benefits, especially in neurodegenerative diseases like Alzheimer’s and Parkinson’s. This study investigates smoking prevalence across mental health conditions, and cognitive impairments in various psychiatric disorders, and explores the possible cognitive health benefits of nicotine. Methods: Data on age and gender distribution, smoking prevalence, …
Published in Research & Reviews: A Journal of Drug Design & Discovery · Vol. 12, Issue 1, 2025 · pp. 16–23 Read article
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Targeting PTPN22 in Arthritis: Molecular Docking and Pharmacokinetic Evaluation of Artemisia vestita Compounds
Abstract: Rheumatoid arthritis (RA) is a long-term autoimmune condition characterized by inflammation of the synovial membrane, commonly resulting in swelling, pain, stiffness, and overall fatigue. Protein tyrosine phosphatase non-receptor type 22 (PTPN22) has been identified as a risk factor linked to various autoimmune diseases, including RA. In the PTPN22 gene, two missense Single nucleotide polymorphisms (SNPs) are associated with autoimmune conditions. The R620W (C1858T, rs247660) variant in exon 14 has been …
Published in International Journal of Bioinformatics and Computational Biology · Vol. 3, Issue 1, 2025 · pp. 20–31 Read article
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Java’s Enduring Popularity: Unraveling the Factors Behind Its Preference
Abstract: Java remains one of the most widely used programming languages across various industries, owing to its robust architecture, platform independence, and extensive ecosystem. Its versatility, scalability, and security make it a preferred choice for developing a wide range of applications, from enterprise software to mobile and web solutions. This study delves into the key factors contributing to Java’s sustained relevance in software development, highlighting its adaptability to evolving technological trends. …
Published in Recent Trends in Programming languages · Vol. 12, Issue 1, 2025 · pp. 8–15 Read article
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Gesture-Based Cursor Control: A Comprehensive Review of Techniques and Applications
Abstract: Although hand gesture detection for man-machine interfaces has advanced recently, many systems still have issues with background and lighting. We have developed a rapid motion history image-based system to categorize dynamic hand motions and a face detection method to adaptively detect skin color. For the up, down, left-, and right-hand gesture classifiers, four sets of haar-like directional patterns were trained. To operate different household appliances, six hand gestures were defined, …
Published in International Journal of Electrical and Communication Engineering Technology · Vol. 3, Issue 1, 2025 · pp. 9–13 Read article