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412 articles for “Gene targeting”
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Polymer Chemistry-Driven Approaches for Improved Therapeutic Delivery
Abstract: Polymer chemistry has revolutionized pharmaceutical technology by enabling the development of advanced drug delivery systems with improved precision, stability, and therapeutic outcomes. This review explores the role of polymer design, synthesis, and functionalization in the development of responsive and targeted drug carriers. Emphasis is placed on various types of polymers—biodegradable, synthetic, natural, and stimuli-responsive—and their suitability for drug delivery platforms such as nanoparticles, micelles, hydrogels, dendrimers, and implants. The physicochemical …
Published in Journal of Polymer & Composites · Vol. 13, Issue 6, 2025 Read article
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Hydroxylated Chalcone Derivatives as Future Aldose Reductase Inhibitors: Discovery through Docking Technique
Abstract: The research endeavors molecular docking assisted exploration of ALR inhibitory perspectives of some B-ring substituted hydroxyl group (A-ring) containing chalcone compounds against human aldose reductase in complex with NADP+ and the inhibitor IDD594 (PDB ID: 1US0) by utilizing the iGEMDOCK (Genetic Evolutionary Method for Molecular Docking) software. The present investigation immensely focused on the human aldose reductase inhibitory perspectives of some hydroxylated chalcone compounds. The inhibition of the enzyme by …
Published in Research and Reviews : Journal of Computational Biology · Vol. 8, Issue 1, 2019 · pp. 8–12 Read article
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Health Status of Adolescents in India: A Review Article
Abstract: The term adolescence refers “to emerge” or “achieve identity” is a new concept, in development thinking. Universally, the age group of 10–19 years is thought to be the time of pre-adulthood. It is obvious that in India, age cut-off points of youths have been settled distinctively under various projects keeping in view the targets of that approach or program. For instance, young people in the draft Youth Policy have been …
Published in Research and Reviews: A Journal of Health Professions · Vol. 7, Issue 1, 2017 · pp. 5–8 Read article
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Advances in Polymer Chemistry for Biomedical Applications: A Focus on Wearable Therapeutic Devices
Abstract: Polymer chemistry has significantly contributed to the evolution of biomedical materials, particularly in the development of wearable therapeutic devices. The combination of biocompatible polymers with advanced composite materials has led to the creation of flexible, durable, and patient-friendly medical support systems. These innovations have transformed healthcare by providing non-invasive and comfortable solutions for managing chronic pain and musculoskeletal disorders. Recent advancements in polymer chemistry have focused on three key areas: …
Published in Journal of Polymer & Composites · Vol. 13, Issue 5, 2025 · pp. 7–15 Read article
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Collection and Evaluation of Ber Germplasm
Abstract: An experiment to identify suitable ber germplasm was conducted at Horticulture Research Centre (HRC) fruit orchard, Regional Agricultural Research Station (RARS), Bangladesh Agricultural Research Institute (BARI), Jamalpur, Bangladesh during the fruiting season of 2016-2017. Fifty-eight accessions collected from different parts of Bangladesh were included in the study. The scion of the collected germplasm was grafted on 10 years old ber plant and the age of grafted branches was 3 years …
Published in Research & Reviews : Journal of Agricultural Science and Technology · Vol. 6, Issue 3, 2017 · pp. 24–39 Read article
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Phytotherapeutic Potential of Melaleuca: An Integrative Review of Phytochemistry and Antimicrobial, Antifungal, Antioxidant, and Antiviral Mechanisms
Abstract: Melaleuca alternifolia and other species of the Melaleuca genus stand out for the broad spectrum of pharmacological properties attributed to their bioactive compounds, such as monoterpenes, sesquiterpenes, flavonoids, and polyphenols. This study aimed to critically review and analyze scientific evidence produced between 2005 and 2025 regarding the antimicrobial, antifungal, antioxidant, and antiviral activities of Melaleuca, correlating its phytochemistry with molecular mechanisms of action. For this purpose, an integrative literature review …
Published in Research & Reviews : Journal of Herbal Science · Vol. 15, Issue 2, 2026 · pp. 16–30 Read article
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RFID Technology Adoption in Libraries: A Review of Current Trends and Challenges
Abstract: The radiofrequency identification system (RFID) makes it possible for devices like computers or machines to automatically recognize things, record metadata, or control certain targets. Identifying objects that are out of direct line of sight is feasible thanks to a technology called radio frequency identification, or RFID. For administering the automated library and detecting theft, libraries are using themost recent technologies. The inventory, issuance, and return status of books, gadgets, and …
Published in Recent Trends in Electronics Communication Systems · Vol. 10, Issue 2, 2023 · pp. 1–6 Read article
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Review on Advanced Molecular Diagnostic Tools and Their Applications
Abstract: Although the diagnosis of diseases is still primarily based on conventional methods (staining, culture, biochemical analysis), a series of advanced molecular diagnostic tools are increasingly introduced and incorporated in the workflow of clinical laboratories worldwide. These tools, such as polymerase chain reaction, northern blotting, restriction length polymorphism, flow cytometry, southern blotting, fluorescent in situ hybridization, agarose gel electrophoresis and pyrosequencing that are based on either the properties of nucleic acids …
Published in Research and Reviews : A Journal of Life Sciences · Vol. 3, Issue 3, 2013 · pp. 21–33 Read article
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A Research on Thermal Analysis of FSAE Brake Disc
Abstract: Since we all know brakes area unit the foremost vital a part of the vehicles the disc brake is a wheelbrake that slows rotation of the wheel by the friction caused by pushing brake pads against a brakedisc with a set of calipers. Braking system represents one in every of the foremost basic safetyimportant parts in trendy vehicles. Brake absorbs kinetic Energy of the rotating parts (Wheels) andthe energy is …
Published in Journal of Refrigeration, Air conditioning, Heating and ventilation · Vol. 8, Issue 1, 2021 · pp. 1–8 Read article
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Recent Update on Advanced Drug Delivery System
Abstract: Over the past decade, there has been a growing interest in the use of artificial intelligence (AI) technology for analysing and interpreting biological or genetic data, accelerating drug discovery, and identifying selective small-molecule modulators or rare molecules in addition to predicting their behaviour. The use of artificial neural networks (ANNs) for the rapid analysis of massive amounts of data, the development of novel hypotheses and treatment plans, the prediction of …
Published in International Journal of Advance in Molecular Engineering · Vol. 1, Issue 1, 2023 · pp. 22–30 Read article
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Advancements in Polymer Chemistry for Biomedical Applications: A Focus on Injection Guides
Abstract: Polymers have revolutionized biomedical applications, offering versatility, biocompatibility, and cost-effective manufacturing. This paper explores the role of polymer chemistry in the development of an advanced injection guide for precise drug delivery, aiming to enhance both safety and efficiency in clinical settings. Emphasis is placed on polymer selection, structural design, and functional modifications to improve injection procedures. By leveraging biodegradable and biocompatible polymers, the guide minimizes adverse tissue reactions while ensuring …
Published in Journal of Polymer & Composites · Vol. 13, Issue 4, 2025 · pp. 129–136 Read article
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Dynamic Vibration and Damping Analysis of Sustainable Nano-Reinforced Polymer Composite Elements for Vehicle Suspension Applications
Abstract: This paper presents an analytical investigation into the dynamic vibration characteristics of nano-reinforced polymer composite elements intended for vehicle suspension applications. A single-degree-of-freedom (SDOF) quarter-car model is employed to derive fundamental expressions for natural frequency, damping ratio, logarithmic decrement, and displacement transmissibility. The primary contribution lies in establishing explicit analytical linkages between material-level viscoelastic properties specifically storage modulus and loss modulus and system-level suspension parameters including stiffness and damping coefficients. …
Published in Journal of Polymer & Composites · Vol. 14, Issue 3, 2026 · pp. 561–570 Read article
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An Overview on the Management cum Treatment of Nephropathy in Type-1 Diabetes Mellitus
Abstract: The motive of this review is to keep updated with the medical nonfictions, the projected early natural arrangement of diabetic nephropathy, the theories behind the root of its pathogenesis pathophysiology, diagnosis and its supervision. Type 1 diabetes is an autoimmune disease characterized by advanced destruction of pancreatic beta cells by genetic and environmental factors which primes to an absolute necessity of insulin for survival and conservation of health; while Diabetic …
Published in Research and Reviews : A Journal of Medical Science and Technology · Vol. 9, Issue 3, 2020 · pp. 19–38 Read article
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PREDICTIVE LEARNING POWERED BY AI AND SOPHISTICATED STUDENT ENGAGEMENT TECHNIQUES
Abstract: The contemporary landscape of education has witnessed a paradigm shift in integrating advanced technologies that have revolutionized the learning experience. Innovative methodologies have emerged to address longstanding challenges, such as enhancing student engagement, accurately predicting academic performance, and personalizing the learning journey. However, despite the numerous benefits that technology brings to education, there remains a crucial hurdle - sustaining student motivation and engagement. Traditional teaching methodologies often struggle to generate …
Published in International Journal of Behavioral Sciences · Vol. 3, Issue 1, 2026 · pp. 127–140 Read article
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Rumen Microbial Adaptation to Dietary Shifts: Mechanisms, Challenges, and Implications for Sustainable Ruminant Production
Abstract: Rumen microbiota play a central role in the digestion and fermentation of dietary components, directly influencing the health and productivity of ruminants. Dietary shifts, such as transitioning from forage-based diets to concentrate-rich diets or incorporating feed additives, induce significant changes in the composition, structure, and functional dynamics of the rumen microbial community. These adaptations, while essential for maintaining microbial homeostasis, can also lead to transient imbalances, including risks of acidosis, …
Published in Research & Reviews : Journal of Ecology · Vol. 15, Issue 1, 2026 · pp. 17–26 Read article
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Novel Synthesis of Encapsulated Super Paramagnetic Iron Nanoparticles (Fe3O4) and its Evaluation in Drug Delivery System
Abstract: Nanoparticles can be defined as solid, submicron, colloidal particles ranging in size from 10–100 nm in diameter, generally but not necessarily made of natural or synthetic polymers, in which drugs can be adsorbed, entrapped, that exhibit new or enhanced size-dependent properties as compared to microparticles. Iron oxide nanoparticles are often magnetic by nature, which means that they obey Coulomb’s law, and can be manipulated by an external magnetic field gradient. …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 7, Issue 2, 2016 · pp. 11–24 Read article
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A Comprehensive Review on Premature Hair Graying: Factor Contributing, Pathogenesis, Prevention Strategies, and Natural Therapeutic
Abstract: Premature graying of hair (PGH), also known as early canities, is an increasingly common dermatological concern characterized by the loss of natural hair pigmentation before the expected age. Hair color is primarily determined by the quantity and type of melanin synthesized by melanocytes within the hair follicle. Disruption in melanocyte function, survival, or melanin synthesis leads to hair graying. Multiple intrinsic and extrinsic factors contribute to PGH, including genetic predisposition, …
Published in Research and Reviews: A Journal of Health Professions · Vol. 16, Issue 1, 2026 · pp. 13–20 Read article
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Diet-Driven Enhancement of Immune Resilience, Disease Resistance, and Performance: Mechanistic Insights, Nutritional Interventions, and Implications for Sustainable Dairy Development
Abstract: This review synthesizes current knowledge on how dietary strategies can strengthen immune resilience, improve disease resistance, and enhance productive performance in dairy systems while advancing sustainable development. Immune function in dairy cattle is profoundly influenced by nutrition, with energy, protein, essential amino acids, fatty acids, vitamins, minerals, and bioactive compounds playing critical roles in shaping both innate and adaptive immune responses. Suboptimal nutrition impairs immune competence, increases susceptibility to infectious …
Published in Research and Reviews : A Journal of Immunology · Vol. 16, Issue 2, 2026 · pp. 15–24 Read article
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Impact of invading fish on native species
Abstract: The term "alien species" refers to organisms that have been intentionally or unintentionally introduced outside of their natural range. These organisms have the ability to establish self-sustaining populations, spread beyond the initial point of introduction, and have a negative impact on the environment and the economy. Through crossbreeding with closely related native species, these fish with diverse genetic make-up cause the formation of a new group of organisms with different …
Published in Research and Reviews : A Journal of Life Sciences · Vol. 13, Issue 2, 2023 · pp. 11–15 Read article
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Advances in Diagnostic Techniques in Veterinary Medicine
Abstract: Diagnostic techniques play a crucial role in veterinary medicine for accurate disease identification, treatment planning, and monitoring of animal health. This review article explores the latest advancements in diagnostic tools and technologies used in veterinary medicine, focusing on imaging modalities, molecular diagnostics, and point-of-care testing. The first section discusses the advancements in imaging modalities, including digital radiography, computed tomography (CT), magnetic resonance imaging (MRI), and ultrasonography. These technologies have revolutionized …
Published in Research and Reviews : Journal of Veterinary Science and Technology · Vol. 12, Issue 1, 2023 · pp. 1–4 Read article