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622 articles for “potential treatments”
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An Expected Cardiovascular Disease Detection Using Deep Learning Techniques
Abstract: Many avoidable deaths globally are caused by CVD, often due to individuals remaining unaware of their risk factors until severe symptoms, such as heart attacks or strokes, appear. This study utilizes retinal images as the dataset to explore the potential of retinal imaging as a non-invasive diagnostic tool for early detection of cardiovascular diseases (CVD). The delay in diagnosis and treatment highlights the need for sophisticated diagnostic instruments that can …
Published in Research and Reviews : A Journal of Medical Science and Technology · Vol. 14, Issue 2, 2024 Read article
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Organometallic Osmium Compounds in Cancer Therapy
Abstract: The exploration of organometallic complexes with osmium as potential anticancer agents was indeed an area of ongoing research. These complexes were being investigated for their unique properties and mechanisms of action against cancer cells. However, it’s essential to note that the field of scientific research is dynamic, and new findings may have emerged since then. Organometallic complexes with osmium can be designed to exhibit specific features that make them promising …
Published in International Journal of Advance in Molecular Engineering · Vol. 1, Issue 2, 2023 · pp. 01–25 Read article
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Nutritional, Preventive, and Therapeutic Potential of Ma-ul-Shae’er (Barley Water) in the Unani System of Medicine: A Holistic Viewpoint
Abstract: In the Unani methodology of managing diseases, Ilaj-bil-Ghiza (dietotherapy) serves as a foundational principle. The initial course of treatment for any ailment entails prescribing specific diets or regulating the quality and quantity of food intake. In recent times, there has been a heightened public awareness regarding the health advantages of functional foods and nutraceuticals for disease prevention and overall well-being. Unani medicine provides a methodical classification of food, taking into …
Published in Research and Reviews: A Journal of Medicine · Vol. 14, Issue 1, 2024 · pp. 18–25 Read article
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Targeting PTPN22 in Arthritis: Molecular Docking and Pharmacokinetic Evaluation of Artemisia vestita Compounds
Abstract: Rheumatoid arthritis (RA) is a long-term autoimmune condition characterized by inflammation of the synovial membrane, commonly resulting in swelling, pain, stiffness, and overall fatigue. Protein tyrosine phosphatase non-receptor type 22 (PTPN22) has been identified as a risk factor linked to various autoimmune diseases, including RA. In the PTPN22 gene, two missense Single nucleotide polymorphisms (SNPs) are associated with autoimmune conditions. The R620W (C1858T, rs247660) variant in exon 14 has been …
Published in International Journal of Bioinformatics and Computational Biology · Vol. 3, Issue 1, 2025 · pp. 20–31 Read article
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Synthesis and Evaluation of Novel Peroxisome Proliferator Activated Receptor-γ (PPAR-γ) Agonists for the Treatment of Diabetes
Abstract: A series of novel thiazolidinedione derivatives as peroxisome proliferator activated receptor-gamma (PPAR-gamma) agonists bearing different fatty acid esters and amides as substituents in the positions 3 and 4 of the benzylidene moiety have been designed, synthesized and tested as potential antihyperglycemic agents. The compounds containing stearic acid (A1TU, A2TU, A3TU, A2TS and A3TS) exhibited the maximum activity (64.7-70.3 % BG reduction) among all the synthesized compounds. The capric acid containing …
Published in Research and Reviews: A Journal of Toxicology · Vol. 6, Issue 2, 2016 · pp. 1–12 Read article
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Therapeutic Potential of Terminalia arjuna Bark in the Management of Hemorrhoids: A Comprehensive Review
Abstract: Background: Hemorrhoids appear frequently among anorectal disorders since they create vascular swelling together with pain symptoms, while leading to bleeding and mucosal tissue tending to slide out. Though effective therapy exists, traditional treatments produce various adverse effects and lead to recurrence and inconsistent patient following of medical recommendations over the long term. Plantbased therapeutic medicines have gained rising demand, which leads experts to investigate medicinal plants with established pharmacological effects. …
Published in Research & Reviews: A Journal of Pharmacognosy · Vol. 12, Issue 2, 2025 · pp. 22–32 Read article
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Molecular Docking of Cocculus hirsutus Phytocompounds with the Selective DENV Virus Stereotypes
Abstract: Dengue is a tropical disease with a high infection rate worldwide. Though treatments are available for the symptoms, anti-dengue drugs are unavailable. To tackle this issue, the study aims to shortlist the potential phytocompounds from Cocculus hirsutus medicinal plant, prevalent in South and South East Asia. Using molecular docking and ADME analysis, two potential compounds possessing high drug-likeness are identified namely, Sinococuline and Morphinan.
Published in International Journal of Genetic Modifications and Recombinations · Vol. 1, Issue 1, 2023 · pp. 17–29 Read article
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Evaluation of Polysaccharide-Based Membranes for Transdermal Drug Delivery in Chronic Pain Management
Abstract: In order to improve treatment effectiveness and patient compliance, chronic pain management is still a major challenge in modern healthcare, requiring creative medication delivery methods. The potential of polysaccharide-based membranes for transdermal drug delivery is assessed in this work, with particular attention to chitosan, alginate, and hydroxypropyl methylcellulose (HPMC). Fourier-transform infrared spectroscopy (FTIR) and scanning electron microscopy (SEM) were two characterization techniques used to assess the membranes' physical and chemical …
Published in International Journal of Membranes · Vol. 1, Issue 2, 2024 · pp. 28–38 Read article
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Cardiovascular Modeling with Computational and Mathematical Methods
Abstract: The cardiovascular system, a complex network responsible for delivering life-sustaining oxygen and nutrients throughout the body, is a prime target for advanced understanding and improved therapies. Due to the inherent difficulties in directly observing internal physiological processes and the complexities of interactions within the system, computational and mathematical modeling have emerged as powerful tools in cardiovascular research. This article explores the significance of these methods in unveiling the heart's secrets …
Published in Research & Reviews: A Journal of Bioinformatics · Vol. 12, Issue 2, 2025 · pp. 11–21 Read article
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Digital Psychiatry: A Narrative Review on AI Positive Role in Mental Health
Abstract: Artificial Intelligence has rapidly evolved into a formidable instrument within the domain of mental healthcare, fundamentally altering the way we understand awareness, diagnosis, intervention and emotional regulation. This narrative review explores AI’s potential to foster positive mental health through tools such as natural language processing, machine learning, deep learning and computer vision. These technologies promise earlier detection of mental disorders, customized treatment plans and responsive emotional support. Yet, alongside these …
Published in Current Trends in Signal Processing · Vol. 15, Issue 3, 2025 · pp. 1–13 Read article
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A Comprehensive Review on Federated Learning in Disease Detection
Abstract: Healthcare data, which is frequently dispersed among various organisations, has enormous potential to improve predictive analytics and illness identification. However, there are substantial privacy & legal obstacles to sharing this private data for centralised model training. Federated Learning is a paradigm shift that allows several organisations to work together to build a global model without disclosing raw patient information. Federated Learning uses a larger dataset to provide more reliable insights …
Published in Emerging Trends in Personalized Medicines · Vol. 3, Issue 1, 2026 · pp. 1–21 Read article
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A Review on Applications of Artificial Intelligence (AI) in Parkinsons’s Disease Diagnosis and Treatment and Its Future Challenges
Abstract: Parkinson’s disease (PD) is a long-term, progressive neurodegenerative disorder that mainly occurs in people older than 60 years, affecting nearly 1% of this population. It is chiefly marked by the loss of dopaminergic neurons in the substantia nigra, a crucial brain region responsible for controlling motor functions. The resultant dopamine deficiency significantly disrupts motor control, manifesting in clinical symptoms such as tremors, bradykinesia, muscle rigidity, and postural instability. While PD …
Published in Research and Reviews: A Journal of Neuroscience · Vol. 15, Issue 3, 2025 · pp. 1–15 Read article
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In-Silico Repurposing of Antipsychotic Drugs Against Novel Protein Targets in Multidrug-Resistant Mycobacterium tuberculosis
Abstract: Multidrug-resistant TB is a growing worldwide health concern, particularly in high-burden areas. Resistance to frontline drugs like isoniazid and rifampicin is caused by mutations in key Mycobacterium tuberculosis proteins. Given the difficulty of developing new antibiotics, medication repurposing offers a good alternative. The potential use of molecular docking to target resistance-associated TB proteins with FDA-approved antipsychotic drugs is investigated in this work. Three proteins were selected: InhA (PDB ID: 5W07), …
Published in Research & Reviews: A Journal of Drug Design & Discovery · Vol. 13, Issue 1, 2026 · pp. 49–63 Read article
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A Comprehensive Review on Male Infertility
Abstract: The failure to attain a clinical pregnancy naturally after one year of unprotected intercourse is termed as infertility. Some of the factors that contribute to Infertility are late marriages, advanced age, genetics and lifestyle to name a few. To tackle this scenario, infertile and sub fertile couples take the aid of assisted reproductive technology. Intra uterine insemination (IUI), In vitro fertilization (IVF), Intra cytoplasmic sperm injection (ICSI), surgical sperm retrieval …
Published in Research and Reviews : A Journal of Life Sciences · Vol. 15, Issue 3, 2025 · pp. 95–103 Read article
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Inspirations on De-addiction to Alcoholism and Drug Abuse in Our Ancient Indian Yogic Texts
Abstract: It has become obvious that `the war on drugs` has not dampened the use, abuse and trade of drugs; In fact, their use has increased. It is now long overdue to look into other reasons as to why drug use is so prevalent, especially in the modernized world, and how ancient knowledge of human being and spiritualized focus systems like yoga can contribute to our understanding of our tendency towards …
Published in Research and Reviews : A Journal of Ayurvedic Science, Yoga and Naturopathy · Vol. 6, Issue 3, 2019 · pp. 38–43 Read article
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Stiff Person Syndrome: Advances in Understanding, Diagnosis, and Treatment of a Rare Autoimmune Disorder
Abstract: Stiff Person Syndrome (SPS) is a rare and complex autoimmune neurological disorder characterized by progressive muscle stiffness, rigidity, and painful spasms. This chapter provides a comprehensive overview of SPS, exploring its pathophysiology, clinical presentation, diagnostic challenges, and current treatment approaches. We discuss the latest research findings, including the role of autoantibodies, genetic factors, and environmental triggers in the development of SPS. The chapter examines various diagnostic methods, emphasizing the importance …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 14, Issue 3, 2024 · pp. 35–43 Read article
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Assessment of Animal Trials Conducted on Protectivity of Potential Sub-unit and Recombinant Vaccines against Pasteurella multocida B:2
Abstract: Haemorrhagic septicaemia, caused by Pasteurella multocida serotypes B:2 and E:2, is an acute, fatal and septicaemic disease of bovines occurring as catastrophic epizootics in most tropical regions of Asia and Africa. As chemotherapeutic treatment of P. multocida infections is expensive and ineffective, prevention of disease outbreaks following immunization is the most potent tool. Although, various vaccine formulations as alum precipitated, oil adjuvant, multiple emulsion and live attenuated vaccines are currently …
Published in Research and Reviews : A Journal of Immunology · Vol. 6, Issue 2, 2016 · pp. 1–12 Read article
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Water Sanitation and Waterborne Disease Incidence among Households: A Cross-Sectional Study
Abstract: The study was conducted to assess water sanitation practices and the incidence of waterborne diseases among households in a selected ward of Koodalloor Panchayath, Kottayam, Kerala. The objectives were to assess the sources of household water, evaluate water sanitation and safety practices, and identify the incidence of waterborne diseases among family members during the previous year. A community-based descriptive study design was adopted. A total of 138 households were selected …
Published in Journal of Nursing Science & Practice · Vol. 16, Issue 2, 2026 · pp. 26–30 Read article
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Physiotherapy Interventions in Prostate Cancer in the North-Eastern India Especially in Assam: A Review
Abstract: A growing body of evidence indicates potential benefit of exercise in Cancer patients but a little is known about exercise promotion in cancer services. The study is based on the Physiotherapy interventions in the prostate cancer patients in North-east India based on the samples, population studied and treatment plans in Dr. B. Borooah Cancer Institute, Guwahati, Assam. The main objective of the study was to make the people of India …
Published in Research and Reviews: Journal of Oncology and Hematology · Vol. 2, Issue 3, 2013 · pp. 11–16 Read article
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A Study of the Effect of Sodium Hydroxide and Sodium Lauryl Sulfate Surface Treatments on Natural Fibers
Abstract: Due to its accessibility, environmental friendliness, renewability, CO2-neutrality, flexibility, low density, and low cost, natural fibre (NF) can have a significant impact on the area of fibre reinforced polymer composite (FRPC) as a reinforcing material. Banana fiber (BF)/calotropis gigantea fiber (CGF) could be a potential candidate for synthetic FRPC replacement. Plant derive banana and calotropis gigantea fibers are valuable NFs that are abundantly available in Bangladesh. The purpose of this …
Published in Journal of Thin Films, Coating Science Technology & Application · Vol. 9, Issue 2, 2022 · pp. 1–11 Read article