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552 articles for “O(n)” (ranking capped at the first 2,000 matches — narrow the search to see the rest)
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Advancing Cancer Vaccine Development through CRISPR/Cas9 Technologies and Future Opportunities
Abstract: The advent of CRISPR/Cas9 genome editing has revolutionized the cancer immunotherapy market, offering unprecedented precision and versatility in the development of next-generation cancer vaccines. This review examines how CRISPR technologies are being integrated into various stages of cancer vaccine development including neoantigen discovery, dendritic cell engineering, cancer cell reprogramming, and tumor microenvironment modulation. In the area of neoantigen discovery, CRISPR enables rapid identification and validation of tumor-specific mutations, thereby supporting …
Published in International Journal of Vaccines · Vol. 2, Issue 2, 2025 Read article
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Unveiling the Silent Threat: The Escalation and Defence Against Antibiotic Resistance
Abstract: The global challenge of antibiotic resistance presents a significant risk to public health, driven by multifaceted factors worldwide. This issue, akin to the impacts of climate change, requires concerted efforts at national and international levels to mitigate its consequences. Antibiotics have revolutionized modern medicine, enabling critical interventions like surgeries, transplants, and cancer treatments. However, without global collaboration, we face significant setbacks across medical, social, and economic domains. Initiatives to address …
Published in International Journal of Antibiotics · Vol. 2, Issue 2, 2025 · pp. 1–26 Read article
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Magnetic and Radioactive Nanoparticles for Improved Theranostics and AI Assisted Radiation Therapy
Abstract: Nanoparticles based therapeutic and theranostics technique is becoming an active area of research in nanomedicine. The sensitivity, biocompatibility, and stability of magnetic and radioactive nanoparticles determine their functionality. This research highlights the impacts of magnetic and radioactive nanoparticles on therapeutic techniques namely, cell therapy, gene therapy, and tissue regeneration. Then, it is intended to brief a principal role of these therapeutic techniques to envisage theranostics medicine and radiation therapy using …
Published in International Journal of Advance in Molecular Engineering · Vol. 3, Issue 2, 2025 · pp. 10–21 Read article
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SoloRider: An Autonomous Self-Balancing Electric Bike for Sustainable Urban Mobility
Abstract: Rapid urbanization has intensified challenges such as traffic congestion, parking inefficiency, and environmental degradation. While autonomous vehicle research predominantly focuses on four-wheel platforms, lightweight two-wheelers remain comparatively underexplored. Two-wheelers are a great option for sustainable urban transportation because of their many benefits, including their small size, lower energy consumption, better manoeuvrability, and lesser infrastructure requirements. This paper presents SoloRider, a conceptual autonomous self- balancing electric two-wheeler de- signed for sustainable …
Published in International Journal of Electronics Automation · Vol. 4, Issue 1, 2026 Read article
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Light-Dark Cycle Disruption in Hypothalamus Tissue of Mus Musculus Causes Change in the Expression of Gm45928 Gene
Abstract: The majority of organisms on earth display consistent 24-hour rhythms in their physiology and behavior due to circadian biology. Light and dark cycles play a key role in setting our internal body clock, which controls things like our sleep patterns, hormone levels, body temperature, and metabolism. The disruption of the light-dark cycle has significant effects on the molecular and behavioral rhythms of the circadian clock of hypothalamus. Gm45928 is a …
Published in International Journal of Cell Biology and Cellular Functions · Vol. 3, Issue 1, 2025 · pp. 32–46 Read article
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Understanding the Dynamics of Biogenic and Anthropogenic Aerosols in the Atmosphere
Abstract: This study explores the complex interactions between marine aerosols, biogenic organic matter, and anthropogenic pollutants, highlighting their implications for climate and air quality. It is established that submicron-sized marine aerosols, primarily of biogenic origin, play a crucial role in cloud condensation nuclei (CCN) concentration, particularly during periods of high biological oceanic activity (HBA). The chemical composition of marine aerosols is significantly influenced by the ocean's annual biological cycle, with seasonal …
Published in International Journal of Atmosphere · Vol. 1, Issue 1, 2024 · pp. 15–22 Read article
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The Role of Optimism in Reducing Psychological Distress Amongst Women in Urban Areas
Abstract: This paper aims to explore the role of optimism in reducing psychological distress among women living in urban areas. Psychological distress, encompassing anxiety, depression, and chronic stress, has become increasingly prevalent due to the fast-paced and demanding nature of urban life. Women, in particular, face unique stressors including work-life imbalances, financial pressures, safety concerns, and societal expectations, which contribute significantly to elevated levels of mental strain. Finding healthy coping strategies …
Published in International Journal of Trends in Humanities · Vol. 2, Issue 2, 2025 Read article
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In Silico Docking Analysis to Identify Therapeutic Benzoic Acid Derivatives for Acute Myeloid Leukaemia
Abstract: Background: The study is anchored to initiate subjugation against modern cancer therapy for Acute Myeloid Leukaemia (AML) which involves natural therapeutics as an alternative therapy that would degrade the prospect of adverse side effects along with anti-cancer properties. Objectives: Collate the various characteristics of Giltertinib with natural benzoic acid derivative phytochemicals for a disquisition regarding their similarities and differences in the context of providing adverse side effects. Methods: ADME toxicity …
Published in International Journal of Cell Biology and Cellular Functions · Vol. 1, Issue 2, 2023 · pp. 50–63 Read article
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Intelligent Decision Support System for Production Planning and Control in an Automotive Assembly Line
Abstract: The automobile industry has realized the importance of Intelligent Decision Support Systems (IDSS) to improve production planning and control on assembly lines. In the context of automobile manufacturing, this review paper examines the most recent developments, methodology, and applications of IDSS. Key trends, obstacles, and possibilities are discovered through an in-depth examination of the literature. Examining real-world case studies and success stories, the integration of artificial intelligence (AI) and machine …
Published in International Journal of Industrial and Product Design Engineering · Vol. 1, Issue 1, 2023 · pp. 16–21 Read article
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Railway Track Safety System
Abstract: Railway Track Safety System (RTSS) is a comprehensive monitoring system specifically designed for the Indian railways. It consists of three subsystems that target specific challenges faced by the railways. Our main focus is on addressing four key problems. The first two issues involve cracks in the rails and foreign objects on the tracks. Cracks can occur naturally or be intentionally created to derail trains. Objects like stones can accidentally roll …
Published in International Journal of Industrial and Product Design Engineering · Vol. 2, Issue 1, 2024 · pp. 29–33 Read article
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Universities in India: Study of Various Types of Universities Operational in India as of 2024 From Faculty Perspective
Abstract: The Indian university system, a legacy of British colonial rule, has witnessed significant growth post-independence. The recent implementation of the National Education Policy (NEP) 2020 further accelerates this expansion, aiming to dismantle the affiliation system and foster the growth of autonomous colleges and universities. This study explores the forms, traits, and difficulties of Indian universities, revealing their variegated environment. It looks at how various institutions respond to the rising demand …
Published in International Journal of Education Sciences · Vol. 2, Issue 1, 2025 · pp. 62–73 Read article
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Virulence Factors in pathogens :mechanisms of infection & disease progression
Abstract: Pathogens, like bacteria, viruses, fungi, and parasites, have evolved specialized tools – known as virulence factors – that help them infect hosts, escape the immune system, and cause disease. These factors play a key role in determining how severe an infection becomes, how quickly it spreads, and how the body responds. Some pathogens use adhesins to stick to host cells, while others produce toxins that damage tissues or disrupt normal …
Published in International Journal of Pathogens · Vol. 2, Issue 1, 2025 · pp. 6–11 Read article
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A Study to Evaluate the Impact of Nurse-led Intervention on Competency Level Regarding Care of Patients on Mechanical Ventilators Among ICU Nurses Working in Selected ICUs at Pt. Bd Sharma PGIMS Rohtak
Abstract: Introduction: The nurse caring for mechanically ventilated patients must be skilled and possess a deep understanding, along with specialized knowledge, of mechanical ventilators (MV). This study is intended to evaluate the impact of nurse-led intervention on competency levels regarding the care of patients on MV among ICU nurses. Objective: To assess the pre- and post-test knowledge, practices, and attitudes of ICU nurses, evaluate the effectiveness of nurse-led interventions on the …
Published in International Journal of Emergency and Trauma Nursing and Practices · Vol. 2, Issue 2, 2024 · pp. 59–94 Read article
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Effects of Kangaroo Mother Care on the Physiological, Behavioral, and Psychosocial Outcomes of Preterm Infants in Various Hospitals in Karnataka
Abstract: Background: Kangaroo mother care (KMC) is a technique that encourages skin-to-skin contact, offering various physiological, behavioral, and psychosocial benefits for preterm infants. The objective is to assess the impact of KMC on the physiological, behavioral, and psychosocial development of premature babies. Study Design: This was a quasi-experimental research investigation. Materials and Methods: A purposive sample of sixty premature infants and their mothers was drawn from neonatal intensive care units (NICUs) …
Published in International Journal of Women's Health Nursing And Practices · Vol. 2, Issue 2, 2024 · pp. 10–19 Read article
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Challenges of E-learning for Learners
Abstract: E-learning, the use of digital technologies for education, has become increasingly popular in recent years. However, learners face several challenges in this mode of learning. This abstract explores some of the key challenges faced by learners in e-learning environments. E-learning environments often lack the interpersonal engagement found in traditional classrooms, such as collaborative discussions, peer support, and networking opportunities, which can result in feelings of isolation and reduced motivation. Success …
Published in International Journal of Machine Systems and Manufacturing Technology · Vol. 3, Issue 2, 2025 · pp. 7–15 Read article
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Marital Rape: Legal And Social Perspective
Abstract: Worldwide, marital rape continues to be a prevalent form of sexual assault and domestic violence, defying growing international condemnation and awareness. Feminist ideologies serve as the foundation for this pervasive affliction, which rips apart victims' trust and stifles their relationships. Gender inequality continues to be prevalent in India, a country where societal norms and legal frameworks frequently fall behind. As opposed to popular belief, matrimony does not confer authorization to …
Published in Recent Trends in Social Studies · Vol. 1, Issue 1, 2024 · pp. 13–16 Read article
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Effectiveness of a Planned Teaching Programme on Primigravid Mothers' Awareness of Specific Natural Pain Relief Techniques Used During Labor in Particular Bangalore Hospital
Abstract: Background: Pain is an exciting sensation and is caused by the stimulus during labor. Always Pain plays a major role in labor in empowering the women, whereby they triumph by giving delivery to the newborn. Objectives: Assess the knowledge level about selected natural pain relief methods. Methodology: A quantitative research approach and the design used in this study was a pre-experimental research design. Sixty primigravid mothers were selected for the …
Published in International Journal of Midwifery Nursing And Practices · Vol. 1, Issue 1, 2023 · pp. 9–16 Read article
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Study on Chemical Insights into Alzheimer's Disease: Amyloid Beta and Tau Protein Interactions
Abstract: Background: Alzheimers disease (AD) is the most prevalent form of dementia, affecting millions of individuals worldwide and posing significant challenges to healthcare systems. The disease is characterized by a gradual decline in cognitive functions, particularly memory, reasoning, and the ability to perform daily activities. Aim & objective: To study chemical insights in alzheimers disease, especially amyloid beta and tau protein interactions Results & discussion: The results of this review highlight …
Published in International Journal of Brain Sciences · Vol. 2, Issue 1, 2025 · pp. 37–46 Read article
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A Retrospective Study to Assess the Incidence of Anaemia Among Pregnant Women Admitted in a Tertiary Care Centre, Jalandhar, Punjab
Abstract: Background: Anemia during pregnancy is a common and preventable condition that contributes significantly to adverse maternal and neonatal outcomes, including preterm delivery, low birth weight, and increased maternal morbidity. Despite the implementation of various national health programs in India, the burden of anemia among pregnant women remains high, particularly in rural regions. Objective: To assess the incidence and severity of anemia among pregnant women admitted to a tertiary care center …
Published in International Journal of Women's Health Nursing And Practices · Vol. 3, Issue 2, 2025 · pp. 38–42 Read article
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A Low Embodied Energy Approach for Early Design Decisions in Agritourism Centers in Pune
Abstract: Agritourism is an idea that empowers and trains the rural family, organization, or individual to generate alternative sources of income by transforming their traditional agricultural land into a tourist attraction. Agritourism is the practice of attracting visitors to an area used primarily for agricultural purposes. It could be described as – rural/agricultural environments + farm commodities + tourism services = agritourism. It gives visitors an experience to stay in a …
Published in International Journal of Rural and Regional Development · Vol. 3, Issue 1, 2025 · pp. 29–41 Read article