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344 articles for “Gene prediction”
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Drug Screening Using Stem Cell Technology
Abstract: Stem cell technology in drug screening has transformed the research and development sector of pharmaceuticals. Although stem cells imitate their human counterparts in terms of both safety and potential, it is a new paradigm for mimicking diseases of humans and scale measuring for toxicity. These tissues will, therefore, be more predictive of what will happen in humans during clinical situations, compared to conventional cell lines or animal models, since they …
Published in Research & Reviews: A Journal of Drug Design & Discovery · Vol. 12, Issue 3, 2025 · pp. 42–51 Read article
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Quantification of Snow/Glacier Melt Impacts of Historical and Future Climate Change on Eastern Himalayan River
Abstract: Millions of the population on Eastern Himalayan Rivers (EHR) totally depend on, domestic use, agriculture, and hydropower. Several studies found that climate warming threatens this EHR's hydrological regime. In order to understand the hydrologic response of their headwaters and how climate change affects streamflow, a hydrological modeling study is conducted in the Teesta River Basin (TRB) in EHR using an open-source Quantum Geographical Information System (QGIS) with semi-distributed QSWAT1.5 (Soil …
Published in Journal of Polymer & Composites · Vol. 13, Issue 1, 2025 · pp. 508–524 Read article
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Transforming Rare Disease Diagnosis with AI
Abstract: Artificial intelligence is changing healthcare fast. It is making diagnoses accurate, helping doctors get better results, and streamlining how care works. This paper looks at how AI shows up in healthcare right now – where it is already making a difference, what is working, and what is still tricky. The focus is on machine learning, natural language processing, and computer vision. Particular attention is given to using AI in diagnosing …
Published in Research and Reviews : Journal of Computational Biology · Vol. 15, Issue 1, 2026 Read article
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Parametric optimization of COF of fabricated AA6082/Si3N4/C/Al2O3 composite
Abstract: In the present experimental investigation AA6082/Si3N4/C/Al2O3 composite was successfully fabri-cated using stir casting technique combined with electromagnetic stirrer for wear resistance applica-tions. The produced AA6082/Si3N4/C/Al2O3 composite exhibits improved tribological and me-chanical and properties, according to the experimental results. The generated composite has a micro-hardness range of 60 to 110 HV and an average UTS of 150 to 200 MPa. The tribological perfor-mance was evaluated using a pin on disc tribometer. …
Published in Journal of Polymer & Composites · Vol. 12, Issue 2, 2024 · pp. 144–152 Read article
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Designing Self-Optimizing Operating Systems: Information-Theoretic Approaches to Thread Scheduler Implementation
Abstract: Thread Level Scheduling (TLS) in multi-core and many-core processor environments represents a critical frontier in next-generation operating system design. As computing systems grow increasingly heterogeneous and concurrent, traditional scheduling strategies often rely on heuristics or localized resource metrics, frequently overlooking the deeper, quantifiable relationships and uncertainties inherent in complex concurrent workloads. This study explores the application of information-theoretic approaches, specifically entropy-based task allocation, mutual information-driven dependency analysis, and channel capacity-inspired …
Published in Journal of Operating Systems Development & Trends · Vol. 12, Issue 3, 2025 · pp. 31–39 Read article
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A Comprehensive Survey on IoT-Enabled and Hand Gesture Controlled Robotic Arm Using Blynk IoT and OpenCV
Abstract: This venture presents an IoT-enabled and hand gesture-managed robot arm that operates in three distinct modes: automated control, IoT-based control via the Blynk app, and gesture-based control using OpenCV. The gadget integrates a NodeMCU microcontroller for wireless verbal exchange and management, with MQTT protocol enabling real-time messaging among the devices. In automated mode, the robotic arm plays predefined tasks autonomously. In IoT mode, users can remotely manage the arm using …
Published in Journal of Advancements in Robotics · Vol. 12, Issue 3, 2025 · pp. 35–40 Read article
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IoT and Smart Sensors for Structural Health Monitoring: Trends, Challenges, and Future Directions
Abstract: Structural Health Monitoring (SHM) plays a critical role in ensuring the safety, resilience, and sustainability of civil infrastructure systems. In recent years, the convergence of Internet of Things (IoT) technologies and smart sensor systems has revolutionized the field of SHM. This integration enables continuous, real- time monitoring, facilitates predictive maintenance, and reduces the costs associated with structural inspections. IoT-based SHM frameworks leverage wireless sensor networks, cloud computing platforms, and intelligent …
Published in Recent Trends in Sensor Research & Technology · Vol. 12, Issue 3, 2025 · pp. 1–6 Read article
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IoT Sensors to Monitor Pipeline Pressure and Flow Rate Combined with ML-Algorithms to Detect Leakages
Abstract: In the field of fluid mechanics, pipelines are the lifeblood of industries, transporting everything from natural gas and oil to water and chemicals. Maintaining their integrity is paramount for safety, economic efficiency, and environmental protection. Traditional leak detection methods explained in fluid mechanics can be slow, expensive, and sometimes fail to identify small leaks early enough to prevent significant damage. However, the convergence of Internet of Things (IoT) and Machine …
Published in Recent Trends in Fluid Mechanics · Vol. 12, Issue 2, 2025 · pp. 40–48 Read article
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A study on IoT and AI for Predictive Modeling and Control of Infectious Disease Transmission
Abstract: Background: The global response to novel and recurring infectious diseases is frequently hindered by surveillance systems that are slow, siloed, and reactive. Traditional epidemiology relies on retrospective analysis of clinical reports, often missing the critical early phase of autocatalytic spread. The urgency of modern public health necessitates a shift toward real-time, predictive intelligence. Methods: This study investigates the development and deployment of a synergistic paradigm integrating the Internet of Things …
Published in International Journal of Pathogens · Vol. 2, Issue 2, 2025 Read article
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Analysis of Die Corner Gap Formation for Strain Hardening Materials in ECAP Through an Upper Bound Sensitivity Approach: A Comparative Study
Abstract: In recent work, using a proposed central composite factorial analysis, the upper-bound theorem's theoretical concept for the equal channel angular pressing process are used. The upper-bound theorem-based theoretical solutions consider Tresca friction conditions and varied fillet radii at the die channel junction. When using AA5083's uniaxial mechanical properties, isotropic nonlinear work hardening is assumed. The ratio of the cumulative effective plastic strain to the time generated by the deformation zones, …
Published in Trends in Machine design · Vol. 12, Issue 3, 2025 · pp. 1–22 Read article
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The Next Era of Solid-State Innovation: Beyond Silicon
Abstract: The semiconductor industry is getting close to the physical and economic boundaries of silicon-based technology. A new era of solid-state innovation is beginning. Beyond Silicon: The Next Era of Solid-State Innovation looks at the materials, device layouts, and manufacturing methods that are about to change the way electronics and energy work. The article talks about improvements in wide- and ultra-wide-bandgap semiconductors, two- dimensional materials, and quantum and neuromorphic systems that …
Published in International Journal of Solid State Innovations & Research · Vol. 3, Issue 2, 2025 · pp. 19–23 Read article
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Unified Mass–Energy Dissolution Cosmology (UMEDC): A Staged Framework for Cosmic Energy Transformation and Late-Time Acceleration
Abstract: The ΛCDM model successfully describes the universe’s expansion but remains fundamentally descriptive: it assigns fixed densities to matter, dark matter, and dark energy without providing a unifying physical mechanism behind their coexistence or evolution. In this work, we introduce the Unified Mass–Energy Dissolution Cosmology (UMEDC), a novel framework based on the staged transformation M → DM → DE, where ordinary matter gradually dissolves into a dark-matter-like reservoir, which subsequently transforms …
Published in International Journal of Universe · Vol. 1, Issue 2, 2025 · pp. 18–34 Read article
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Drug-Induced Liver Injury: Hepatotoxicity and Treatment - A Literature Review
Abstract: Drug-induced liver injury (DILI) is a major clinical and regulatory challenge, posing risks to patient safety and drug development worldwide. As the primary organ responsible for xenobiotic metabolism, the liver is particularly susceptible to toxic injury from prescription drugs, over-the-counter medications, herbal products, and dietary supplements. Drug-induced liver injury (DILI) accounts for a substantial proportion of acute liver failure cases and remains a leading cause of post-marketing drug withdrawal. Its …
Published in Research and Reviews: A Journal of Toxicology · Vol. 16, Issue 1, 2026 · pp. 1–17 Read article
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Automation and new mechanical technologies changing the next industrial age
Abstract: The fast growth of automation and new mechanical technologies is changing the way industries work, making manufacturing and production systems more efficient, accurate, and flexible than ever before. This article looks at how sophisticated mechanical design, robotics, and intelligent automation technologies can work together and how they can improve productivity, lower costs, and make operations more sustainable. To show how mechanical engineers are influencing the next industrial era, we look …
Published in International Journal of Manufacturing and Production Engineering · Vol. 3, Issue 2, 2025 · pp. 18–23 Read article
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Harvestify: ML Based Tool for Home Gardening and Farming
Abstract: This study presents a cutting-edge application that will transform home gardening and agriculture practices using machine learning (ML) approaches. The main goal is to provide data-driven insights to home gardeners and farmers, enabling them to implement efficient and sustainable farming practices. Crop disease detection, fertiliser recommendation, and a community section for user engagement comprise the three main elements that make up the system's architecture. The Crop Disease Detection module analyses …
Published in International Journal of Electrical and Communication Engineering Technology · Vol. 2, Issue 2, 2024 · pp. 18–28 Read article
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Chemical Reactor Design and Analysis: A Review
Abstract: Chemical reactors play a critical role in industries such as oil and gas, chemical processing, and power generation, where they operate under extreme pressure and handle highly toxic, compressible fluids. The growing need for alternative energy sources has led to an increased demand for vessels capable of withstanding high pressure and temperature, especially in the chemical and petroleum industries. Recent innovations in chemical reactor technology have concentrated on creating new …
Published in Recent Trends in Fluid Mechanics · Vol. 12, Issue 2, 2025 · pp. 49–59 Read article
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Application of GIS tools to the Improvement of Energy Supply in PV Rooftop Installations
Abstract: Present work studies the energy supply from photovoltaic (PV) installations in industrial conglomerates using the rooftops as a surface to install the PV panels. The study is based on a modelling procedure that takes into account the specific characteristics of the rooftop, shape, size, azimuth and inclination, using GIS tools to identify these parameters for every single rooftop. Modelling has been developed modifying the tilt angle of the PV panel …
Published in Journal of Remote Sensing & GIS Read article
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AI-Designed Functionally Graded Polymer Composites for Multifunctional Thin Films
Abstract: The design of multifunctional polymer composite thin films requires simultaneous optimization of mechanical, optical, barrier, and thermal properties—objectives often in conflict when using conventional homogeneous materials. This study presents an artificial intelligence-driven framework for designing functionally graded material (FGM) architectures in polymer nanocomposite thin films. We integrated machine learning with physics-based modeling to optimize compositional gradients across film thickness, achieving superior performance compared to homogeneous and discrete multilayer alternatives. A …
Published in Journal of Polymer & Composites · Vol. 14, Issue 2, 2026 · pp. 1026–1041 Read article
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Thermal Performance of Concentrating Solar Panels
Abstract: The study shows a detailed analysis of the thermal performance of concentrating solar panels and the temperature increase due to concentrated solar radiation. This work proposes a configuration to reduce temperature rise, maintain good panel efficiency, and increase output power. The configuration is based on a sandwich structure including a phase change material (PCM), which absorbs the thermal energy excess generated by the concentrated solar radiation onto the PV panel. …
Published in Journal of Thermal Engineering and Applications · Vol. 12, Issue 1, 2025 · pp. 1–10 Read article
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ML-Driven Optimization Framework for the Analysis, Design, and Development of Efficient Wireless Power Transfer Systems for EV Charging
Abstract: The fast uptake of electric vehicles (EVs) has heightened the necessity of effective, dependable and convenient charging systems. The Wireless Power Transfer (WPT) systems can be taken as a potential solution as they allow charging cells without contact, without any risks, and without any overcrowding; the efficiency of the system is strongly influenced by the alignment of coils, the fluctuations of air-gaps, the conditions of the loads, and geometrical arrangements …
Published in International Journal of Manufacturing and Production Engineering · Vol. 4, Issue 1, 2026 · pp. 1–9 Read article