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394 articles for “Evidence”
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Histological Effects of the Antibiotic Gentamicin on the Ovarian Tissue of Female White Laboratory Rats
Abstract: This study aimed to evaluate the histological alterations induced by Gentamicin in the ovarian tissue of white laboratory rats. A total of 12 adult female rats were used and randomly divided into two groups, with each group consisting of six animals. The experimental group received Gentamicin at a dose of 120 mg/kg body weight administered as an injection once daily, while the control group received an equivalent volume of normal …
Published in International Journal of Antibiotics · Vol. 3, Issue 1, 2026 · pp. 1–8 Read article
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Kisunla (Donanemab): A Novel Breakthrough Illuminating a Path to Better Alzheimer’s Outcomes
Abstract: Background: Alzheimer’s disease (AD) is a progressive neurodegenerative condition marked by cognitive decline, memory loss, and loss of independence. Despite decades of extensive research, disease-modifying treatments have been limited in success. Recent therapeutic advancements have led to the development of monoclonal antibodies targeting amyloid-beta (Aβ) plaques, particularly the pyroglutamate-modified variant, a key pathological hallmark of AD. Objectives: This review aims to explore the therapeutic potential of Donanemab (Kisunla), a novel …
Published in Research and Reviews: A Journal of Neuroscience · Vol. 15, Issue 3, 2025 · pp. 37–45 Read article
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Molecular Docking-Based Analysis of Rauvolfia serpentina Alkaloids Targeting HPV E1 and L1 Proteins for Antiviral Therapeutic Potential
Abstract: Human papillomavirus (HPV) is a major cause of cervical cancer and other epithelial cancers. E1 and L1 proteins are crucial to the virus's lifespan. E1 is a viral helicase that is needed for HPV DNA replication, and L1 is the main structural capsid protein that builds the virion and infects target cells. Going after these proteins is a good way to stop viruses from spreading. In this case, Rauvolfia serpentina, …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 17, Issue 1, 2026 · pp. 100–113 Read article
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Quantitative Mass Balance Modelling for the Synthesis and Production of Ten High-Volume Insecticides
Abstract: This study presents a detailed quantitative mass balance analysis for the industrial synthesis and production of ten high-volume insecticides: acequinocyl, acetamiprid, acynonapyr, alpha-cypermethrin, benzpyrimoxan, bifenazate, bifenthrin, bistrifluron, broflanilide, and bromofos, focusing on material flows, process efficiencies, and environmental implications. These compounds, spanning diverse chemical classes like neonicotinoids, pyrethroids, and meta-diamides, are essential for crop protection but pose challenges due to resource-intensive syntheses and waste generation. For each insecticide, standardized manufacturing …
Published in Journal of Modern Chemistry & Chemical Technology · Vol. 16, Issue 3, 2025 · pp. 36–55 Read article
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Cosmeceuticals: Integrating Therapeutic Functionality into Cosmetic Science
Abstract: Cosmeceuticals are a quickly growing group of skincare products that are in between cosmetics and drugs. These products have biologically active components that are said to provide medical or drug-like advantages for a number of skin problems, including ageing, hyperpigmentation, acne, and damage from the sun. Cosmetics are not medications, but cosmeceuticals are made to affect skin function at the cellular level. This article talks about what cosmeceuticals are, how …
Published in Recent Trends in Cosmetics · Vol. 2, Issue 2, 2025 · pp. 19–35 Read article
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A Study to Develop a Planned Teaching Programme and Demonstration on Intravenous Cannulization for Staff Nurses and Assess Its Effectiveness in Terms of Gaining Knowledge and Practice at Selected Hospital in Delhi, India
Abstract: Introduction: Intravenous cannulization is a fundamental skill for staff nurses, crucial for effective patient care and treatment delivery. Despite its importance, variations in technique and knowledge gaps can impact patient outcomes and safety. This study addresses this need by developing a structured educational program specifically designed to improve the knowledge and practical skills of nursing staff in intravenous cannulization. Objectives of the study were: a) To assess the knowledge of …
Published in Journal of Nursing Science & Practice · Vol. 15, Issue 2, 2025 · pp. 35–41 Read article
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Biodiversity Loss and Its Impact on Dietary Land Diversity and Nutritional Status: A Comprehensive Review
Abstract: Habitat destruction, climate change, overexploitation, and agricultural intensification contribute to the current predicament in global food systems: Loss of biodiversity means less plant and animal species to be utilized. This study examines and synthesizes the available literature in PubMed and Scopus on how losses in biodiversity adversely affect people’s diets and nutritional status, especially in the case of malnutrition and missing key micronutrients of certain demographic cohorts. Principal factors are …
Published in International Journal of Land · Vol. 2, Issue 2, 2025 · pp. 25–30 Read article
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Persistent Atmospheric and Ecosystem Impacts of Enteric Methane Emissions from Intensive Livestock Production Systems
Abstract: Enteric methane emissions from intensive livestock production systems exert a significant long-lasting influence on atmospheric stability and ecosystem integrity. Recent observations confirm that global methane emissions continued to rise through the early 2020s, with total emissions exceeding 620 teragrams per year by 2024, driven by expanding ruminant production and associated feed systems. Anthropogenic sources accounted for more than 330 teragrams per year, reflecting sustained growth in agricultural and fossil fuel …
Published in International Journal of Atmosphere · Vol. 2, Issue 2, 2025 · pp. 18–38 Read article
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Human Resource Cell Support for Employees Mental Health and Well Being
Abstract: This study explores the persistent issue of mental health in the workplace and evaluates how collaboration among human resource (HR) teams can improve the day-to-day experiences of employees living with mental health conditions. To capture an accurate and timely understanding of effective organizational responses, the research employs a mixed-methods approach to examine the strategies required to address the ongoing mental health challenge. Additionally, this study aims to close the gap …
Published in OmniScience: A Multi-disciplinary Journal · Vol. 15, Issue 3, 2025 Read article
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Analysis of Die Corner Gap Formation for Strain Hardening Materials in ECAP Through an Upper Bound Sensitivity Approach: A Comparative Study
Abstract: In recent work, using a proposed central composite factorial analysis, the upper-bound theorem's theoretical concept for the equal channel angular pressing process are used. The upper-bound theorem-based theoretical solutions consider Tresca friction conditions and varied fillet radii at the die channel junction. When using AA5083's uniaxial mechanical properties, isotropic nonlinear work hardening is assumed. The ratio of the cumulative effective plastic strain to the time generated by the deformation zones, …
Published in Trends in Machine design · Vol. 12, Issue 3, 2025 · pp. 1–22 Read article
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A Cross-Sectional Study to Assess the Impact of Smartphone Use on Daily Activities of Living Among Undergraduate Students in a Selected College in Bangalore
Abstract: Introduction: Smartphones are compact devices which are commonly used by undergraduate students. Nowadays it is evident that around 4.76 h are spent by the students for entertainment and are at risk of addiction and have impact in terms of academic, physical, social, economic, psychological and behavioral activities on daily basis. Aim: The aim of the study was to assess the impact of smartphone use on daily activities of living among …
Published in Journal of Nursing Science & Practice · Vol. 15, Issue 3, 2025 · pp. 35–43 Read article
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Terminalia arjuna: The Medicinal Tree
Abstract: Over 85% of the medications used in both conventional and alternative medical systems come from plant sources. The stem bark of Terminalia arjuna (T. arjuna) is rich in minerals, flavonoids, and glycosides. T. arjuna bark is unique because flavonoids have been shown to have anti-inflammatory, lipid-lowering, and antioxidant properties, and glycosides are cardiotonic. A variety of topics related to its ethnomedical, phytochemical, pharmacological, and clinical significance to different medical conditions …
Published in Research and Reviews : A Journal of Ayurvedic Science, Yoga and Naturopathy · Vol. 12, Issue 3, 2025 · pp. 27–34 Read article
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The Impact of Nutrition on Sports Performance and Academic Success: A Study Among University Athletes – Eastern Technical University of Sierra Leone
Abstract: University athletes operate within dual-performance environments that require simultaneous academic and athletic excellence. Nutrition plays a critical role in supporting both physiological performance and cognitive functioning; however, limited empirical work has examined its combined influence on athletic and academic outcomes within university athlete populations, particularly in low-resource contexts. This study aimed to investigate the relationship between nutritional practices, sports performance, and academic achievement among university athletes at the Eastern Technical …
Published in Research & Reviews : Journal of Food Science & Technology · Vol. 15, Issue 1, 2026 · pp. 16–27 Read article
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Factors Affecting Mammalian Embryo Culture: A Detailed Review
Abstract: Human IVF has made remarkable progress, but optimizing the in vitro environment remains essential and crucial for supporting embryo development and improving overall clinical outcomes in assisted reproductive technologies (ART). Even with advances in complex culture media, incubator design, and laboratory workflows, embryos grown outside the body are still exposed to chemical and physical stressors that can significantly affect their developmental potential. In this review, we discuss key chemical stressors, …
Published in International Journal of Cell Biology and Cellular Functions · Vol. 4, Issue 1, 2026 Read article
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An Empirical Analysis of Cost, Time, and Quality Relationships Using Correlation and Regression Techniques
Abstract: Cost, time, and quality have been recognized as the three key dimensions that determine construction project performance and are commonly represented through the "Project Management Triangle." However, despite their theoretical linkage, there is limited empirical evidence to quantify the nature of their relationships, particularly within developing construction markets. This paper seeks to contribute to addressing this shortfall by investigating the specific influence of cost and schedule variations upon quality outcomes …
Published in Journal of Construction Engineering, Technology & Management · Vol. 16, Issue 1, 2026 · pp. 52–60 Read article
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Postbiotics Unveiled: Mechanistic Insights and Therapeutic Implications in Obesity.
Abstract: The burgeoning global obesity epidemic necessitates innovative therapeutic approaches, and postbiotics, bioactive compounds arising from microbial fermentation, have emerged as promising contenders in reshaping obesity management. This comprehensive review explores the multifaceted mechanisms by which postbiotics impact obesity, from modulating gut microbiota composition to influencing metabolic pathways and enhancing energy expenditure. The exploration of postbiotics is rooted in a deeper understanding of the gut–brain axis and bidirectional communication between gut …
Published in Emerging Trends in Metabolites · Vol. 3, Issue 1, 2026 · pp. 11–28 Read article
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A Study on accelerating threat of Emerging Infectious Diseases (EIDs) and imperative for a proactive, interdisciplinary Global Health Security Framework
Abstract: Emerging Infectious Diseases (EIDs) represent one of the most critical and persistent threats to global health security in the 21st century. Driven primarily by the synergy of unprecedented human encroachment into wild habitats, climate change-induced ecological disruption, accelerated international travel, and antimicrobial resistance, the frequency and severity of zoonotic spillover events are rapidly increasing. Traditional, reactive public health measures—focused on containment after an emergence—have repeatedly proven insufficient, leading to catastrophic …
Published in International Journal of Tropical Medicines · Vol. 3, Issue 1, 2026 · pp. 8–21 Read article
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Paternal Pre-Pubertal Smoking: Small RNAs, Lasting Marks, and the Hidden Legacy of Early Exposure
Abstract: While the negative effects of maternal smoking during pregnancy are well-established, the lasting and transgenerational impact of paternal pre-pubertal smoking remains a critical, underexplored area. Emerging evidence in sperm epigenetics suggests that cigarette exposure during early male development may create persistent molecular imprints that can affect the health of future offspring. This phenomenon is rooted in the fact that heredity extends beyond the DNA sequence. Sperm carry a complex epigenetic …
Published in Emerging Trends in Personalized Medicines · Vol. 3, Issue 1, 2026 · pp. 1–5 Read article
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Utilization and Socioeconomic Impact of Biofuel Adoption Among Farming Communities in Fatehgarh Sahib, Punjab
Abstract: With the increasing consumption of energy and environmental issues, transformation toward renewable energy is being considered as a trend globally. Biofuels such as biogas and biodiesel provide potential alternative to fossil based fuel, particularly, in the rural parts of India, including Punjab. These clean sources, however, are not only contributing to environment but also have a potential to improve the rural economy by saving costs and having better health. Despite …
Published in Research and Reviews : Journal of Crop science and Technology · Vol. 15, Issue 1, 2026 · pp. 38–45 Read article
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Vitamin D Mitigates Inflammation and Downregulates Importin α3 in Non-Alcoholic Fatty Liver Disease (NAFLD)
Abstract: Non-alcoholic fatty liver disease (NAFLD) affects about one-third of the population in the United States and Western countries, reaching up to 90% among obese individuals and those undergoing bariatric surgery. Characterized by hepatic fat accumulation, NAFLD progresses from simple steatosis to non-alcoholic steatohepatitis (NASH), fibrosis, and, in rare cases, hepatocellular carcinoma. Linked intricately with metabolic syndrome, including diabetes and obesity, NAFLD development involves insulin resistance and hyperinsulinemia. Experimental evidence consistently …
Published in International Journal of Cheminformatics · Vol. 4, Issue 1, 2026 Read article