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837 articles for “Clinical”
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MIRDcalc & OLINDA/EXM Dosimetry Software Analysis by SPECT/CT Scan Data of Lu-177 DOTATATE Radionuclide Therapy of NET Patients
Abstract: Accurate dosimetry is essential in nuclear medicine for optimizing radionuclide therapies and ensuring patient safety. In Radiopharmaceutical dosimetry the Medical Internal Radiation Dosimetry (MIRD)Society is the pioneer in organ-level dosimetry providing the fundamental basis for commonly used clinical and research dosimetry software like MIRDOSE and OLINDA/EXM. Recently, in MIRD Pamphlet No. 28, Part 1, the MIRD committee of the Society of Nuclear Medicine and Medical Imaging presented a new Software …
Published in Journal of Nuclear Engineering & Technology · Vol. 15, Issue 2, 2025 · pp. 48–63 Read article
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Machine Learning-Based Disease Prediction: A Comparative Analysis for Diabetes, Brain Tumor, and Parkinson's Disease
Abstract: This paper presents a web-based disease prediction system that integrates machine learning and deep learning techniques to assist in the early detection of Parkinson’s Disease, Diabetes, and Brain Tumors. By utilizing clinical data and MRI images, the platform provides rapid and interpretable predictions to support proactive health management. Logistic Regression models are applied to classify structured datasets for predicting Parkinson’s disease and Diabetes, making use of their effectiveness in binary …
Published in Current Trends in Signal Processing · Vol. 15, Issue 2, 2025 · pp. 44–54 Read article
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Crossroads of Ecology and Medicine: Evaluating Pollutant-Induced Risks to Biodiversity and Human Health
Abstract: Environmental pollution has emerged as a central challenge at the crossroads of ecology and human medicine. The rapid pace of industrialization, urbanization, and agricultural intensification has led to an unprecedented release of pollutants into the air, water, and soil—triggering cascading effects on ecosystems and human health. Pollutants such as particulate matter, heavy metals, pesticides, microplastics, endocrine-disrupting chemicals, and persistent organic pollutants not only degrade biodiversity but also exert multifaceted health …
Published in International Journal of Environmental Noise and Pollution Control · Vol. 3, Issue 1, 2025 · pp. 41–53 Read article
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Engineered Polymer Composites for Non-Surgical Lip Posture Correction in Facial Paralysis
Abstract: Facial paralysis presents significant functional and aesthetic challenges, particularly through lip posture deficits such as drooping and drooling, often inadequately addressed by traditional surgical or drug-based interventions, especially in debilitated patients. This study explores the application of engineered polymer composites in a novel, non-surgical lip posture corrector designed to statically suspend and correct lip position without requiring surgical or dental support. The device utilizes a precisely formulated blend of polymethylmethacrylate …
Published in Journal of Polymer & Composites · Vol. 13, Issue 5, 2025 Read article
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Polymer-Integrated Smart Biomedical Waste Management System Using AI and Sensor-Based Segregation
Abstract: Biomedical waste, which comes from healthcare facilities like hospitals, clinics, and labs, includes both infectious and non-infectious materials. This can range from sharps and pathological waste to pharmaceutical leftovers and general medical trash. If this waste isn't handled, sorted, and disposed of properly, it can pose serious contamination risks, leading to infections, workplace hazards, environmental damage, and public health emergencies. Traditional biomedical waste management often relies on manual sorting, which …
Published in Journal of Polymer & Composites · Vol. 13, Issue 4, 2025 · pp. 172–184 Read article
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Predictive Modeling of Polymer Composites for Medical Implants Using Artificial Intelligence Techniques
Abstract: The use of polymers in biomaterials was now key to designing the next generation of medical implants, which need to be strong and also compatible with living tissue. Tests for biocompatibility, such as those done in the laboratory and by doing experiments on animals, require much time and many resources, so the need for computer-based approaches becomes clear. An artificial intelligence approach was provided in this study to determine how …
Published in Journal of Polymer & Composites · Vol. 13, Issue 6, 2025 · pp. 665–692 Read article
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Formulation and Evaluation of Transdermal Patch to Enhance Treatment of Alopecia
Abstract: The improvement of novel topical sedate conveyance frameworks has picked up noteworthy consideration due to their potential in upgrading the helpful viability and persistent compliance whereas minimizing systemic side impacts. This thinks about centers on the definition and assessment of transdermal patches planned to discharge allicin, the essential naturally dynamic compound determined from garlic (Allium sativum) extricate. Allicin is eminent for its wide range of pharmacological properties, counting antimicrobial, anti-inflammatory, …
Published in Trends in Drug Delivery · Vol. 12, Issue 2, 2025 · pp. 20–33 Read article
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Episiotomy in Nellore Brown Ewe Successfully Relieved Dystocia Due to Vulvo Vestibular Constriction
Abstract: A full term pregnant, primiparous ewe was presented to the Department of Veterinary Clinical Complex, College of Veterinary Science, Proddatur with the history of non-progressive straining persisting for the past 24 hours. The owner reported that attempts had previously been made by local quacks to assist in the delivery, but all the efforts proved unsuccessful, and the condition remained unresolved. The ewe had not shown any signs of improvement following …
Published in Research and Reviews : Journal of Veterinary Science and Technology · Vol. 14, Issue 2, 2025 · pp. 30–34 Read article
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Cervical Leiomyomas: Age associated insights from 3 Year prospective study from Tertiary Care Hospital
Abstract: Cervical leiomyomas are rare benign smooth muscle tumours of cervix, often presenting diagnostic challenges due to their uncommon occurrence and overlapping features with other cervical pathologies. This is a 3-year prospective study involving a total of 460 female subjects who were diagnosed with various gynecologic complications, with a particular focus on cervical leiomyomas. The study aims to provide a comprehensive age-wise distribution of cervical leiomyomas, emphasizing the incidence and prevalence …
Published in Research and Reviews : A Journal of Medical Science and Technology · Vol. 14, Issue 2, 2024 Read article
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Nutraceuticals Unveiled: Exploring the Science, Benefits, and Future of Functional Food
Abstract: The rapidly developing subject of nutraceuticals is critically examined in this review, with a focus on its scientific basis, proven health advantages, and possible future applications in the functional food industry. Key bioactive ingredients that contribute to the therapeutics effectiveness of functional foods, including flavonoids, polyphenols, carotenoids, probiotics, and essential fatty acids, have been identified and characterized as a result of recent developments in nutritional science. Both experimental and clinical …
Published in International Journal of Nutritions · Vol. 2, Issue 2, 2025 Read article
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3D-Printed Polymeric Drug Delivery Systems for Personalized Medicine
Abstract: Personalized medicine has revolutionized healthcare by tailoring treatments to individual patient needs. Among the emerging technologies, 3D printing has demonstrated immense potential in fabricating polymeric drug delivery systems with precise control over drug release, dosage, and bioavailability. These systems offer customized therapeutic solutions, improving efficacy while reducing adverse effects. This paper provides an overview of 3D-printed polymeric drug delivery systems, discussing the types of polymers used, fabrication techniques, applications in …
Published in Journal of Polymer & Composites · Vol. 13, Issue 4, 2025 · pp. 313–325 Read article
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Accelerating Drug Discovery with AI: Transforming the Pharmaceutical Pipeline
Abstract: The revolutionary potential of artificial intelligence (AI) is examined in this essay the pharmaceutical industry, highlighting its application across the drug development lifecycle. Artificial Intelligence, specifically via deep learning models and machine learning (ML) such as GANs, RNNs, and transformers, enhances drug discovery, formulation, toxicity prediction, and clinical trials. It streamlines processes like identification of targets, virtual screening, modelling of structure-activity relationships, and medication repurposing. AI is also employed in …
Published in Research & Reviews: A Journal of Drug Design & Discovery · Vol. 12, Issue 2, 2025 · pp. 77–84 Read article
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A Systematic Review on Leukemia Detection and Classification Techniques Using Gene Expression
Abstract: Early diagnosis of genetic diseases is crucial for effective treatment, especially in the case of Leukemia, a type of blood cancer characterized by abnormal proliferation of white blood cells. This paper presents a systematic review of recent computational techniques for the detection and classification of Leukemia using gene expression data obtained from DNA microarray analysis. The study explores diverse methodologies including machine learning (ML), deep learning (DL), and bio-inspired algorithms …
Published in International Journal of Genetic Modifications and Recombinations · Vol. 3, Issue 2, 2025 Read article
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Advancing Cancer Vaccine Development through CRISPR/Cas9 Technologies and Future Opportunities
Abstract: The advent of CRISPR/Cas9 genome editing has revolutionized the cancer immunotherapy market, offering unprecedented precision and versatility in the development of next-generation cancer vaccines. This review examines how CRISPR technologies are being integrated into various stages of cancer vaccine development including neoantigen discovery, dendritic cell engineering, cancer cell reprogramming, and tumor microenvironment modulation. In the area of neoantigen discovery, CRISPR enables rapid identification and validation of tumor-specific mutations, thereby supporting …
Published in International Journal of Vaccines · Vol. 2, Issue 2, 2025 Read article
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Beyond Generalized Treatment: The Future is Personalized Medicine
Abstract: Personalized medicine, which is also called as precision medicine, is reestablishing the view of new healthcare by replacing the traditional "one-size-fits-all" approach with individual therapies made according to a patients unique genomic organization, environment, and lifestyle. This article talks about the scientific foundation, important applications, ethical challenges, and the significant potential of personalized medicine in enhancing the clinical outcomes. From oncogenic and genetic disorders to chronic diseases, the addition of …
Published in Emerging Trends in Personalized Medicines · Vol. 2, Issue 2, 2025 Read article
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Phyto-Entrapped Carbon Dots as Emerging Nanomaterials for Anti-Cancer Activity
Abstract: Phytoconstituent-loaded carbon dots (C-dots) represent an innovative approach in targeted cancer therapy, combining the therapeutic power of plant-derived compounds with the advanced capabilities of nanotechnology. These ultra-small, biocompatible nanostructures offer excellent fluorescence, tunable surface chemistry, and low toxicity, making them ideal for drug delivery, bioimaging, and theranostic applications. Traditional phytochemicals often face challenges like poor solubility, low bioavailability, and high first-pass metabolism barriers that C-dots help overcome. C-dots synthesized through …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 16, Issue 3, 2025 · pp. 51–63 Read article
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Pharmacogenomics: Unlocking the Genetic Basis of Drug Response for Precision Medicine
Abstract: Pharmacogenomics, a fusion of pharmacology and genomics, explores how genetic variations influence individual responses to medications. This field is revolutionizing modern medicine by moving away from a one-size-fits-all approach toward personalized treatment strategies. By identifying specific genetic markers, pharmacogenomics aims to enhance drug efficacy, minimize adverse drug reactions, and improve overall patient outcomes. Key methodologies in this discipline include candidate gene analysis, genome-wide association studies, and haplotype analysis, all of …
Published in Research & Reviews: A Journal of Drug Design & Discovery · Vol. 12, Issue 2, 2025 · pp. 52–59 Read article
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HPV and Cardiovascular Risk: Unpacking a Novel Link Between Viral Infection and Heart Disease
Abstract: Human papillomavirus (HPV) is best known for its oncogenic potential, yet a growing body of evidence suggests that persistent HPV infection may also contribute to cardiovascular disease (CVD). In 2025, pooled analyses and conference reports galvanized attention by estimating that HPV‐positive individuals have ~40% higher risk of CVD and approximately double the risk of coronary artery disease (CAD) compared with HPV‐negative peers, even after adjustment for traditional risk factors. These …
Published in International Journal of Virus Studies · Vol. 2, Issue 2, 2025 · pp. 1–5 Read article
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Automated Blood Cell Counting and Disease Identification Using Image Processing: Implications for Polymer Composite- Based Biomedical Diagnostic Devices
Abstract: Accurate quantification of blood cells is central to clinical decision-making and to the performance of emerging polymer composite–based diagnostic platforms. This work presents a cost-effective, image-processing pipeline for automated counting of red blood cells (including overlapping cells), white blood cells, and platelets from Leishman-stained peripheral blood smears, and articulates its relevance to polymer composite microfluidic and biosensor devices. Implemented in Python with OpenCV, the workflow performs grayscale conversion, median/Gaussian denoising, …
Published in Journal of Polymer & Composites · Vol. 13, Issue 6, 2025 · pp. 262–270 Read article
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Advances in Polymer Chemistry for Coronary Artery Disease
Abstract: Coronary artery disease (CAD) remains the leading cause of morbidity and mortality worldwide, driving ongoing innovation in therapeutic materials and device design. Polymer chemistry has emerged as a cornerstone in the development of advanced cardiovascular interventions, offering versatile platforms to improve the safety, efficacy, and functionality of implantable devices. This review explores recent advances in the synthesis and application of biodegradable and biostable polymers, focusing on their roles in drug-eluting …
Published in Journal of Polymer & Composites · Vol. 13, Issue 6, 2025 · pp. 710–716 Read article