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1680 articles for “BCS Class II/IV drugs”
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Synthesis of Magnetically Recoverable Nickel (II) Complex-Functionalized Fe 3 O 4 @ISNA (ISNA= Isonicotinic acid) Nanomaterials: Catalytic Studies on Nitrophenol Reduction and TD- DFT Studies
Abstract: In this study, we aimed to develop a novel, environmentally sustainable, and magnetically separable heterogeneous nanocatalyst, denoted as Fe 3 O 4 @ISNA@NiL (where L represents the ligand). The synthesis involved a two-step process, first, isonicotinic acid was chemically grafted onto the surface of iron oxide nanoparticles (Fe 3 O 4 ) to introduce functional groups capable of further chemical modification. Subsequently, a nickel(II) Schiff base monomeric complex was anchored …
Published in Journal of Polymer & Composites Read article
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Birdwatcher’s Assistant: AI- Based Bird Species Classification
Abstract: Many bird species have gone extinct because of human activities and changes in the climate. The loss of habitats is a significant danger to global biodiversity. Therefore, it is important to monitor species distribution and identify the components of biodiversity in an area to develop conservation strategies. The ultimate objective is to build a machine learning model that can accurately differentiate between various bird species based solely on visual cues. …
Published in Journal of Artificial Intelligence Research & Advances · Vol. 12, Issue 1, 2025 · pp. 17–27 Read article
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Detection and Classification of Alzheimer’s Disease Using Deep Learning Technique
Abstract: It is crucial that people with Alzheimer's disease (AD) receive a proper diagnosis to begin preventative action before irreparable brain damage develops. Most people who suffer from Alzheimer's disease (AD), a neurological condition that progresses, are older than 65. The area of interest (ROI) in the hippocampus has been extensively studied for several purposes, including neurological illness research, stress development monitoring, and memory function analysis. Moreover, a connection between Alzheimer's …
Published in Recent Trends in Sensor Research & Technology · Vol. 12, Issue 1, 2025 · pp. 15–20 Read article
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Breakthroughs in Biotechnology for the Regulation of Infectious Diseases
Abstract: Infectious diseases have a heavy impact on both public health and the world’s economies. In most diseases, antibiotic resistance has become widespread over time. A variety of diseases comprising pneumonia, tuberculosis, and gonorrhea go through the same evolutionary processes, which include the formation of drug-resistant pathogens in response to selection pressure from medications and their potential extinction when drug use is ceased. Since the occurrence of drug resistance in serious …
Published in Research and Reviews : A Journal of Biotechnology · Vol. 15, Issue 1, 2025 · pp. 1–25 Read article
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An Overview of Composite Materials: Historical Development, Classification, and Advancements in Natural Fiber-Reinforced Polymer Composites
Abstract: Composite materials have brought about a paradigm shift in numerous industries by integrating distinct components to improve material performance. Consisting of a matrix and reinforcement, composites synergistically combine the unique properties of each constituent to deliver superior strength, enhanced durability, and remarkable flexibility. These attributes have made composite materials indispensable in diverse fields such as automotive, aerospace, construction, and marine engineering. This article provides a comprehensive exploration of the historical …
Published in Journal of Polymer & Composites · Vol. 13, Issue 2, 2025 · pp. 158–175 Read article
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Optimizing Sentiment Analysis with Naïve Bayes and Random Forest Techniques: A Result-based Approach
Abstract: In the increased digitalization, the sentiment analysis and classification have evolved as an eminent area to determine the polarity of positive, negative, and neutral reviews of the customers and users on products. It is an integral application field that employs supervised learning, Machine Learning, and Natural Language Processing concepts. The proposed Semantic Analysis and Classification using Naive Bayes and Random Forest system accomplishes the sentiment polarity by classifying the user …
Published in Journal of Artificial Intelligence Research & Advances · Vol. 12, Issue 2, 2025 · pp. 46–57 Read article
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Botanical Beauty: Exploring the Role of Herbal Drugs in Modern Cosmetics
Abstract: This review provides a concise overview of the burgeoning use of herbal drugs in cosmetics, showcasing their increasing importance in modern skincare formulations. Through an exploration of various herbal plants and their extracts, such as Aloe vera, lavender, calendula, and green tea, among others, the review elucidates the diverse array of benefits these botanicals offer for skin health and overall well-being. By harnessing the therapeutic properties of these natural ingredients, …
Published in Research & Reviews: A Journal of Pharmacognosy · Vol. 12, Issue 1, 2025 · pp. 76–91 Read article
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Prediction of Customer Churn Using Machine Learning Classification Models
Abstract: Customer churn prediction is a critical task in both the telecommunication and medical industries, where retaining customers or patients is essential for ensuring long-term profitability and maintaining high-quality service. To address this, a range of machine learning models—including logistic regression, decision trees, random forests, gradient boosting machines, and support vector machines—were employed to accurately forecast churn behavior. Prior to model training, the dataset underwent thorough preprocessing, which included handling missing …
Published in Journal of Computer Technology & Applications · Vol. 16, Issue 2, 2025 · pp. 86–92 Read article
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Prescription Opioid Use, Misuse and Motivation for Misuse among patients admitted in a drug treatment center
Abstract: Background: Opioid misuse remains a significant public health concern in Nigeria and globally. The risk of misuse complicates opioid prescriptions, potentially leading to overdose and fatal outcomes if not promptly addressed. Objectives: To determine the prevalence of prescription opioid use, misuse, and the underlying motivations for misuse. Method: This study utilized a retrospective cross-sectional design to examine the prevalence and patterns of prescription opioid use and misuse. Data were collected …
Published in Research and Reviews: A Journal of Toxicology · Vol. 15, Issue 2, 2025 Read article
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Exploring the Role of MAPK3 in Major Depressive Disorder: Molecular Docking, Dynamics, and Binding Free Energy Analysis of Natural Compounds as Alternatives to Conventional Drugs
Abstract: Major Depressive Disorder (MDD) is a prevalent neuropsychiatric disorder with limited treatment efficacy and significant side effects associated with conventional antidepressants. Recent studies have highlighted the role of mitogen-activated protein kinase 3 (MAPK3) in the mechanisms underlying MDD, positioning it as a potential target for the development of novel therapeutic drugs. In this study, we employed various computational approaches to explore natural compounds as viable alternatives to synthetic antidepressants. Researchers …
Published in International Journal of Bioinformatics and Computational Biology · Vol. 3, Issue 2, 2025 · pp. 53–68 Read article
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A Comprehensive Analysis of Novel Liposomes: Categorization, Approach, Description, and Present Formulations
Abstract: Liposomes have gained attention as a promising drug delivery system, which come with the advantages of biocompatibility, ability to load hydrophilic and hydrophobic drugs, and they can function for targeted drug delivery. In this regard, this paper offers a comprehensive overview on novel liposomes, including classification, formulation strategies, detailed structures, and current pharmaceutical applications. Recent advances in liposomal drug delivery systems includes, new liposomal architectures (i.e. stealth, targeted, stimuli-responsive, hybrid …
Published in Research & Reviews: A Journal of Drug Design & Discovery · Vol. 12, Issue 2, 2025 · pp. 15–20 Read article
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Pediatric and Geriatric Formulation Tailoring Dosage Form for Age-Specific Needs
Abstract: This comprehensive review addresses the critical challenges and advancements in the formulation of oral medications for pediatric and geriatric populations, who often face unique pharmacokinetic and pharmacodynamic differences. The World Health Organization highlights that nearly 50% of long-term medications are not adhered to, with significant implications for health outcomes. Pediatric patients, due to their developmental stages, and geriatric patients, due to age-related physiological changes, require tailored drug formulations to enhance …
Published in Research & Reviews: A Journal of Drug Formulation, Development and Production · Vol. 12, Issue 2, 2025 · pp. 89–103 Read article
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AGRISMART: Crop and Soil Management System
Abstract: Agriculture has played a crucial role in developing countries where the majority of the rural population relies on it for their livelihoods. A finer-grade crop classification has become crucial in the context of precision agriculture. In recent years, the volume of open image data has grown significantly. This can be used in combination with machine learning techniques to classify crop types in the agricultural industry. The proposed crop species recognition …
Published in Journal of Remote Sensing & GIS · Vol. 16, Issue 3, 2025 · pp. 50–55 Read article
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Ayurveda as a Medium of Healing: A Critical Review of Classical Concepts and Modern Evidence
Abstract: Ayurveda, recognized as one of the world’s oldest holistic healing systems, has its origins in India over 5,000 years ago. Rooted in a philosophy that views health as a harmonious balance of body, mind, and spirit, Ayurveda offers a comprehensive and individualized approach to wellness. This traditional system of medicine is grounded in the concept of the Tridosha Vata, Pitta, and Kapha representing the fundamental bio-energetic forces governing physiological and …
Published in Journal of AYUSH: Ayurveda, Yoga, Unani, Siddha and Homeopathy · Vol. 14, Issue 3, 2025 · pp. 40–44 Read article
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Classification and Comparison of Routing Protocols in Wireless Sensor Networks
Abstract: Recent developments and the overlap of multiple technologies, including distributed signal processing, ad-hoc network routing protocols, embedded systems, integrated circuits, micro electro-mechanical systems, microprocessor hardware, and nanotechnology, have rendered the idea of Wireless Sensor Networks (WSNs) possible. Sensor network nodes are finite with regard to energy, processing capability, and communication bandwidth. Yet, since they can vary with respect to the application and network structure, the routing protocols have received the …
Published in International Journal of Wireless Security and Networks · Vol. 3, Issue 2, 2025 · pp. 35–44 Read article
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Pharmacological Comparison of Turmeric and Non-Steroidal Anti-Inflammatory Drugs in Pain Relief
Abstract: Pain is one of the most frequently encountered clinical symptoms affecting millions globally and is typically treated pharmacologically with nonsteroidal anti-inflammatory drugs (NSAIDs). However, long-term use of NSAIDs is associated with adverse effects such as gastrointestinal, renal, and cardiovascular issues. In recent years, turmeric and its main active compound, curcumin, have received considerable attention for their reported anti-inflammatory, analgesic, and antioxidant properties as natural therapeutic options. This review seeks to …
Published in Research & Reviews: A Journal of Pharmacognosy · Vol. 13, Issue 1, 2026 · pp. 19–28 Read article
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Flexural Vibration of Non-Uniform Beam on Bi-Parametric Foundation Under Harmonic Moving Load with Non-Classical Boundary Conditions
Abstract: The dynamic response to harmonically varying moving loads of non-uniform elastic beam resting on bi-parametric foundation with non-classical boundary condition, time dependent in particular is examined in this paper. Here, the beam is considered non-uniform, with the moment of inertia and the distributed mass varying continuously along the span L as functions of the position 𝑥. In order to guarantee a more stable structure and a reduce risk of resonance, …
Published in International Journal of Mechanical Dynamics and Systems Analysis · Vol. 3, Issue 2, 2025 · pp. 28–42 Read article
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Organic Compounds as Anti-inflammatory Agents, Natural and Synthetic
Abstract: Inflammation diseases still threaten humanity everywhere. For which there is always a continuous demand for immediate medication, the so-called anti-inflammatory drug. Anti-inflammatory organic compounds are either of natural origin or synthetic. Many drugs represent the main constituent of plants. Turmeric, ginger, garlic, spinach, broccoli, ginseng, blueberries, clove, Aloe Vera and pineapple all are plants almost rich in anti-oxidant and flavonoids that reduce inflammation. Researchers still have spent decades of years …
Published in Research & Reviews: A Journal of Drug Design & Discovery · Vol. 13, Issue 1, 2026 · pp. 05–18 Read article
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Biodegradable and Natural Fiber-Reinforced Polymer Composites for Sustainable Biomedical Applications
Abstract: Liposomal drug delivery has evolved into a viable approach in modern pharmacology thanks to its enhanced bioavailability, reduced systemic toxicity, and targeted drug release. Conventional liposomes have limited stability, medicine leakage, and short circulation times among other problems. Overcoming these limits, the inclusion of nano-polymers into liposomal formulations has transformed medication delivery. Thorough research has been done on the potential of nano-polymers including chitosan, hyaluronic acid, polyethylene glycol (PEG), and …
Published in Journal of Polymer & Composites · Vol. 13, Issue 6, 2025 · pp. 420–432 Read article
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Digital Enablers of Nanomedicine: Pharmaceutical Software Across the Lifecycle of Nanotechnology‑Based Drug Products
Abstract: Nanotechnology‑based drug products have rapidly evolved from laboratory concepts to clinically relevant therapies, yet their development is constrained by complex design variables, stringent quality requirements, and emerging regulatory expectations specific to nanomaterials. Pharmaceutical software now plays a central role in the nanomedicine lifecycle, enabling in silico design of nano‑carriers, simulation of nano–bio interactions, control of nanoscale quality attributes during manufacturing, and systematic tracking of safety signals in real‑world use. Integrated …
Published in Nano Trends – A Journal of Nano Technology & Its Applications · Vol. 28, Issue 1, 2025 · pp. 11–16 Read article