Search
294 articles for “health and safety”
-
In-Silico Repurposing of Antipsychotic Drugs Against Novel Protein Targets in Multidrug-Resistant Mycobacterium tuberculosis
Abstract: Multidrug-resistant TB is a growing worldwide health concern, particularly in high-burden areas. Resistance to frontline drugs like isoniazid and rifampicin is caused by mutations in key Mycobacterium tuberculosis proteins. Given the difficulty of developing new antibiotics, medication repurposing offers a good alternative. The potential use of molecular docking to target resistance-associated TB proteins with FDA-approved antipsychotic drugs is investigated in this work. Three proteins were selected: InhA (PDB ID: 5W07), …
Published in Research & Reviews: A Journal of Drug Design & Discovery · Vol. 13, Issue 1, 2026 · pp. 49–63 Read article
-
Environment- friendly Pavement Construction Using Plastic Trash and Reclaimed Asphalt Pavement-An Overview
Abstract: Plastic pollution has emerged as a significant environmental concern, with detrimental effects on ecosystems and human health. As a waste product contaminating air, water, and land, plastic poses a grave threat to the environment, perpetuating a global crisis. Its non-biodegradable nature means that once produced, plastic persists indefinitely, accumulating in landfills, water bodies, and natural habitats. This widespread accumulation of plastic waste not only compromises the aesthetic value of landscapes …
Published in Journal of Polymer & Composites · Vol. 12, Issue 3, 2024 · pp. 116–123 Read article
-
Human Skin Abnormality Detection with Process Similarity Criteria Fit Machine Learning Method
Abstract: This method presents a machine learning method that satisfies the defined conditions for healthy waterside beach activities. The boundary conditions of the normal and abnormal radiation spaces were formulated. The objectives of using a Regression Polynomial with Process Similarity Criteria Fit for skin temperature prediction are justified by the analysis of the existing analytical and machine learning approaches. An algorithm for skin temperature prediction using the theories of similarity criteria …
Published in Research & Reviews: Discrete Mathematical Structures · Vol. 11, Issue 2, 2024 · pp. 17–24 Read article
-
Recent Advancements in Nanobiocomposite-Based Wound Healing and Tissue Regeneration
Abstract: Haemostasis, inflammation, proliferation, remodeling, and other highly coordinated cellular and molecular activities are all part of the complex biological processes of wound healing and tissue regeneration. Following an injury, these stages cooperate to restore tissue integrity and function. However, this normal process is disturbed in many clinical circumstances, especially chronic wounds such diabetic ulcers, burns, and pressure sores. Prolonged inflammation, chronic microbial infection, diminished angiogenesis, and impaired extracellular matrix production …
Published in Journal of Polymer & Composites · Vol. 14, Issue 3, 2026 · pp. 297–318 Read article
-
Real-time Water Quality Analysis Using Fuzzy Logic
Abstract: Nowadays the availability of safe drinking water is very difficult. In our project we are analysing water quality using different parameters like pH, turbidity, temperature and TDS for determining its safety level by monitoring the data from the readings. Moreover, we have a monitoring system for the data and also a webpage where all the data from these system is displayed. The sensors are connected to an Arduino Nano microcontroller …
Published in Journal of Water Pollution & Purification Research · Vol. 13, Issue 2, 2026 · pp. 01–11 Read article
-
Qualitative and Quantitative Effects of Non-Thermal Atmospheric Pressure Plasma and ErCr: YSGG Laser Activation on Surface Remineralization and Fluoride Release of Three Different Fluoride Varnishes
Abstract: Dental caries remains a prevalent oral health concern worldwide, prompting ongoing research into innovative approaches for caries prevention and management. This experimental investigation endeavors to conduct a comparative assessment of the bioactivity, fluoride release kinetics, shear bond strength, and compressive strength of glass ionomer cement (GIC) augmented with three distinct types of inorganic bioactive nanoparticles. Bioactive nanoparticles have garnered interest in dental materials for their potential to enhance material properties …
Published in Journal of Polymer & Composites · Vol. 12, Issue 5, 2024 · pp. 292–303 Read article
-
Neuroinflammation Is Aggravated by the Aqueous Extract of Myrmecodia Platytyrea Tuber
Abstract: Myrmecodia platytyrea, commonly known as the ant plant, is a medicinal epiphyte traditionally used in Southeast Asia for its purported health benefits, including anti-inflammatory, antioxidant, antimicrobial, and anticancer activities. Its tuber contains abundant secondary metabolites, including flavonoids, tannins, phenolic compounds, and saponins. While these phytochemicals are generally associated with therapeutic effects, the biological activity of Myrmecodia extracts varies depending on the type of extract, dosage, and route of administration. In …
Published in International Journal of Brain Sciences · Vol. 3, Issue 1, 2026 · pp. 5–14 Read article
-
Milk Allergy: Significance, Detection and Management
Abstract: Milk allergy is a significant public health issue, particularly among infants and young children, with prevalence rates between 2 and 6% in early childhood, declining to 0.1–0.5% in adulthood. It is an immune-mediated adverse reaction to milk proteins, primarily involving immunoglobulin E (IgE)-mediated responses. Symptoms range from gastrointestinal distress and respiratory complications to severe anaphylaxis. The etiology of milk allergy involves genetic predisposition, environmental factors, an immature immune system, and …
Published in Research and Reviews : Journal of Dairy Science and Technology · Vol. 14, Issue 1, 2025 · pp. 15–19 Read article
-
A Study on Recent Trends in Chemical Sensors for Detecting Toxic Materials
Abstract: Poisonous materials, such as mutagenic, carcinogenic, and poisonous compounds, are widely produced as a result of industrial development. Such materials continue to be hazardous to human health despite stringent management and control procedures. As a result, practical chemical sensors—such as optical, electrochemical, nanomaterial-based, and biological system-based sensors—are needed for the monitoring of dangerous chemicals. For the detection of harmful compounds, numerous new and existing chemical sensors are being created, along …
Published in Journal of Modern Chemistry & Chemical Technology · Vol. 16, Issue 3, 2025 · pp. 26–35 Read article
-
Nutritional Status, Bioactive Properties & Therapeutic Efficacy of Omega-3 Polyunsaturated Fatty Acids Obtained by Green Synthetic Routes
Abstract: Polyunsaturated fatty acids (PUFAs), particularly omega-3 (n-3) fatty acids like eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA), are crucial for human health. They support structural brain development, visual acuity, and cardiovascular function, while also exhibiting potent anti-inflammatory, antioxidant, and antimicrobial properties. Historically, marine fish oil has been the primary dietary source of these essential fatty acids. However, escalating concerns regarding ecological environmental impacts, the oceanic bioaccumulation of heavy metal contaminants, …
Published in International Journal of Nutritions · Vol. 3, Issue 2, 2026 Read article
-
Molecular Docking and Interaction of Anthocyanin Derivatives in Regulating Hippo-taz Pathway for Renal Injuries
Abstract: Introduction: The Hippo pathway plays a pivotal role in renal disease, with Yes-associated protein (YAP) exhibiting promise for combined treatments. The crucial evaluation of YAP-targeted drug safety and efficacy through preclinical studies is imperative. Additionally, α-SMA and SMAD3 emerge as potential therapeutic targets in renal fibrosis, driving ongoing research toward innovative interventions. Materials and Methods: In the systematic identification of therapeutic secondary metabolites, Anthocyanin derivatives were methodically retrieved from the …
Published in International Journal of Genetic Modifications and Recombinations · Vol. 2, Issue 1, 2024 · pp. 23–38 Read article
-
Medicinal Properties of Oxytenanthera abyssinica: A Narrative Review
Abstract: Oxytenanthera abyssinica, a plant local to the African landmass, has gotten a parcel of intrigued in later a long time for its conceivable restorative benefits; it has been utilized in conventional medication for decades since of its assumed mending capabilities. In spite of its long history, careful logical examination into its restorative potential is being attempted. This review paper explore into the multidimensional part of O. Abyssinica is in progressed …
Published in Research & Reviews: A Journal of Pharmacognosy · Vol. 13, Issue 2, 2026 Read article
-
Assessment of Finerenone Safety and Efficacy in Individuals with Type 2 Diabetes and Chronic Kidney Disease
Abstract: Background: In this work, we provide strong evidence for the safety and efficacy of finerenone in people with type 2 diabetes and chronic kidney disease. Our goal is to improve patients' quality of life and general well-being through our research. Aim: Finerenone exhibited a significant decrease in the likelihood of renal and cardiovascular (CV) events in individuals with both type 2 diabetes and chronic kidney disease. This exploratory subgroup analysis …
Published in International Journal of Antibiotics · Vol. 1, Issue 2, 2024 · pp. 06–09 Read article
-
An Evaluation of the Impact of a Nurse-Led Program on Knowledge and Practices Related to Needle Stick Injury Prevention Among 2nd Year B.Sc. Nursing Students at the College of Nursing, PT. B.D. Sharma PGIMS, Rohtak
Abstract: Healthcare workers and nursing students frequently face accidental occupational exposures while caring for patients, with needle stick injuries being the most common form of exposure in healthcare settings. These injuries pose a significant risk of infections. This study aimed to evaluate the awareness and practices related to the prevention of needle stick injuries among second-year B.Sc. Nursing students, assess the effectiveness of a nurse-led intervention in enhancing their knowledge and …
Published in International Journal of Evidence Based Nursing And Practices · Vol. 3, Issue 1, 2025 · pp. 28–66 Read article