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1680 articles for “BCS Class II/IV drugs”
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Scientific Appraisal of Unani Drugs Used in Neurological Disorders
Abstract: Background: Neurological disorders are prevalent and are increasing. The Unani system of medicine provides insights into the pathogenesis, prevention, and treatment of these diseases. Objective: This study explores the Unani perspective on neurological disorders, focusing on therapies and the pharmacodynamics of related medicines. Methods: A comprehensive review of Unani literature was conducted using digital and traditional sources. Unani texts, like “Al Qanoon Fil Tib” by Ibn Sina and “Al Jami …
Published in Research & Reviews : A Journal of Unani, Siddha and Homeopathy · Vol. 13, Issue 1, 2026 · pp. 34–44 Read article
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Evaluating the Role of Pharmacists in Managing Antibiotic Use and Combating Multi-Drug Resistance in Hospital Settings
Abstract: Antibiotic resistance is now one of the crucial health issues of the world, especially in hospitals where high usage of antimicrobials is increasing the rate at which multi-drug resistant (MDR) organisms appear. Misprescription, extended treatment, and over-use of broad spectrum antibiotics play a large role in the development of resistance resulting in the growth of morbidity, mortality and health care expenditure. This review analyses the essentiality of pharmacists in controlling …
Published in International Journal of Antibiotics · Vol. 3, Issue 2, 2026 · pp. 12–19 Read article
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Child Friendly Innovation: A New Era in Pediatrics Drug Delivery Systems
Abstract: Pediatric formulations are becoming more and more popular as a result of advancements in pharmaceutical delivery technology. For young patients, there isn't a safe and effective drug delivery system in place. Since children's pharmacokinetics and pathophysiologic profiles differ from those of adults, it is imperative to design and develop an innovative and appropriate delivery system to provide accurate and dependable medicine administration to pediatric patients. Discussions will be held under …
Published in Trends in Drug Delivery · Vol. 13, Issue 2, 2026 Read article
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Barg-e-Tulsi (Ocimum sanctum Linn.) in Unani Medicine: Bridging Classical Therapeutics with Contemporary Pharmacological Evidence
Abstract: In the Unani System of Medicine (USM), Barg-e-Tulsi (Ocimum sanctum Linn.), commonly known as Tulsi or Holy Basil, is a highly valued medicinal herb that has been extensively used for centuries in the prevention and treatment of various ailments. It occupies an important place in traditional Unani therapeutics due to its broad spectrum of medicinal properties and its effectiveness in managing respiratory, gastrointestinal, neurological, and infectious disorders. Classical Unani scholars …
Published in Research & Reviews : A Journal of Unani, Siddha and Homeopathy · Vol. 13, Issue 2, 2026 Read article
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Enhancing Road Safety with the Latest Breakthrough: Real-time Vehicle Classification, Counting, and Speed Estimation Using YOLOv8n and Deep SORT Algorithm
Abstract: The real-time vehicle classification, counting, and speed estimation system based on YOLOv8n is an important tool for monitoring traffic flow on highways. However, because they are distinct objects from their surroundings, it is still difficult to detect them, which has an impact on how accurate vehicle counts are. To tackle this concern, this paper suggests the implementation of a vision-centric system for real-time vehicle monitoring and identification. The approach involves …
Published in Research & Reviews: A Journal of Embedded System & Applications · Vol. 12, Issue 1, 2024 · pp. 10–18 Read article
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Classifying Abnormalities in Heartbeat Sound
Abstract: Heartbeat sounds play a major role in the detection of various diseases such as heart disease, hyperthyroidism, and high blood pressure in their early stages. In the proposed method, various abnormal and healthy heartbeat audio signals are given as input and the features are extracted using MFCC (mel-frequency cepstral coefficients). Then, a deep learning approach is applied in which the MFCC audio signals are sent to the CNN (convolutional neural …
Published in Research & Reviews: A Journal of Embedded System & Applications · Vol. 12, Issue 1, 2024 · pp. 24–31 Read article
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Classification of Skin Disease Images Using EfficientNetTransfer Learning Technique
Abstract: Melanomous Skin lesions are among the deadliest kinds of cancer. Despite being a very uncommon skin condition, melanoma is responsible for 75% of cancer-related deaths. Dermatologists perform dermoscopy more commonly than any other procedure. Since it aggravates the skin condition, a dermatologist will be the first to identify it during an inspection. Because this strategy depends on the user's visual perception and experience, it can only be used by highly …
Published in Journal of Telecommunication, Switching Systems and Networks · Vol. 11, Issue 1, 2024 · pp. 7–12 Read article
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Evaluation of Machine Learning Classifiers for Sentiment Analysis
Abstract: Sentiment in social media refers to users’ emotions and opinions through their posts and interactions. Sentiment analysis (SA) refers to relating and classifying the sentiments expressed as engagement and interactions between users. When analyzed, tweets frequently produce a large source of clustered data. These data help determine people’s opinions about a variety of motifs. Thus, this study presents an Automated Machine Learning (ML) Sentiment Analysis Model to detect media sentiment. …
Published in Journal of Artificial Intelligence Research & Advances · Vol. 11, Issue 2, 2024 · pp. 141–154 Read article
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Development and Fabrication of Biohydrogel for Targeted Delivery of Delafloxacin for Bacterial Skin Infections
Abstract: The escalating challenge of bacterial resistance necessitates innovative drug delivery systems to enhance the efficacy of antibiotics. This study focuses on the development and optimization of a biohydrogel formulation for the targeted delivery of Delafloxacin, aiming to improve its therapeutic outcomes against resistant bacterial strains. Utilizing a 3² factorial design, biohydrogel formulations incorporating Poly(N-isopropylacrylamide) (PNIPAM) and Genipin were synthesized. The optimization process was guided by Design Expert software, focusing on …
Published in Research & Reviews: A Journal of Drug Design & Discovery Read article
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A Traditional Indian Unani Dynamic Drug Amla (Emblica Officinalis) And Its Unani Pharmacological Activities In The Light of Recent Experimental Studies: A Comprehensive Review
Abstract: Since ancient times, plants have been essential to human development, serving as a primary source of natural remedies. The challenges associated with producing synthetic medications, along with their potential side effects and high costs, have driven researchers around the world to focus on the study of medicinal plants. In recent years, numerous publications have highlighted the role of plant-derived bioactive compounds in treating a wide range of human ailments, underscoring …
Published in Research & Reviews : A Journal of Unani, Siddha and Homeopathy · Vol. 11, Issue 3, 2024 · pp. 21–29 Read article
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Development of Sodium Alginate Beads of Telmisartan Using Emulsion Gelation Method: Formulation and In-Vitro Characterization
Abstract: Introduction: The antihypertensive medication Telmisartan (TEL) is a member of BCS class II, which is distinguished by limited oral rate and extent and water solubility. By localizing the medication release in the stomach, gastro-retentive floating bead devices may be able to address the issues related to partial absorption and the low solubility of TEL. The preparation of TEL floating alginate beads was the aim of this investigation. The current work …
Published in Research & Reviews: A Journal of Drug Formulation, Development and Production · Vol. 11, Issue 3, 2024 · pp. 13–21 Read article
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A Brief Review On Nanoparticles Drug Delivery System Used In Cervical Cancer
Abstract: Among cervical tumor-related deaths worldwide, cervical cancer is a major cause. The limitations of traditional methods, such as chemotherapy and radiation therapy, stem from their adverse effects and increased susceptibility to medications. Despite being seen as innovative options, immune checkpoint inhibitors (ICIs) have rather low clinical response rates. Reliable treatments for patients with metastatic or recurring cervical cancer are currently lacking. Lately, nanomaterials including polymers, liposomes, and dendrimers have been …
Published in Research and Reviews : A Journal of Life Sciences · Vol. 15, Issue 1, 2025 · pp. 30–40 Read article
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Face Detection and Classification for Attendance Systems on Android
Abstract: This work offers a facial recognition-based attendance system with the goal of addressing the drawbacks of traditional manual attendance. The manual attendance procedure can be made more efficient by using facial recognition technologies and mobile platforms. This design is divided into three function modules: attendance sign-in, attendance record, and face recognition system of check on work attendance information input. It also introduces a face detection and classification principle, analyses the …
Published in Current Trends in Signal Processing · Vol. 15, Issue 1, 2025 · pp. 15–22 Read article
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Artificial Intelligence Enhanced Waste Sorting and Classification System for Urban Recycling
Abstract: This study explores the potential of Artificial Intelligence (AI) and Machine Learning (ML) to enhance waste management efficiency within urban environments. Rapid urbanization has resulted in a surge of municipal waste, which current systems often struggle to manage effectively. The proposed AI-enhanced waste sorting and classification system aims to optimize waste collection routes and accurately forecast waste generation trends, thereby reducing operational costs, fuel consumption, and traffic congestion. Additionally, AI-driven …
Published in Current Trends in Signal Processing · Vol. 15, Issue 1, 2025 · pp. 23–32 Read article
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Role of Carboxylesterases in Xenobiotic Metabolism and Detoxification: Insights for Cheminformatics Approaches
Abstract: Xenobiotics, which include a wide range of environmental pollutants, food additives, drugs, and carcinogens, are foreign chemical entities that enter the human body and may accumulate, leading to toxic effects. Phase I and phase II metabolic responses are among the detoxification procedures that are necessary to lessen these negative consequences. This review highlights the pivotal role of carboxylesterases (CES), enzymes involved in the hydrolysis of ester, amide, and thioester bonds …
Published in International Journal of Cheminformatics · Vol. 2, Issue 2, 2024 · pp. 9–17 Read article
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An Insightful Study on SMEDDS Challenges and Potential Strategies
Abstract: Self-microemulsifying drug delivery systems (SMEDDS) have gained attention as an effective approach to enhance the bioavailability of poorly water-soluble drugs. They are innovative lipid-based formulations designed to enhance the solubility, bioavailability, and therapeutic efficacy of poorly water-soluble drugs. The development of SMEDDS involves systematic selection of components based on solubility and emulsification efficiency, followed by optimization of ratios using pseudo-ternary phase diagrams. The resulting formulations are evaluated for droplet size, …
Published in Journal of Polymer & Composites · Vol. 13, Issue 2, 2025 · pp. 311–334 Read article
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Study Review: Molecular Mechanisms of Nanoparticle-Cell Interaction – Implications for Drug Delivery and Toxicity
Abstract: The application of nanoparticles in drug delivery and biomedical therapies holds great promise, yet their interaction with cells and the underlying molecular mechanisms remains areas of active research. This study explores the molecular mechanisms of nanoparticle-cell interactions, focusing on the effects of gold nanoparticles (AuNPs) and silica nanoparticles (SiNPs) in human cancer cell lines (HeLa and MCF-7). The study examines how nanoparticles are internalized by cells, their impact on cellular …
Published in Research and Reviews: A Journal of Toxicology · Vol. 15, Issue 2, 2025 · pp. 31–40 Read article
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Revolutionizing School Schedules: An Arduino-Based Automatic Class Bell System with Real-Time Precision
Abstract: A sound that evokes nostalgia, signals transitions, and dictates the rhythm of academic life. However,the traditional reliance on manual bell ringing is prone to human error, inconsistencies, and inflexibility. This work explores the design and implementation of an Arduino-based automatic class bell system leveraging a Real-Time Clock (RTC) module to provide accurate and reliable bell timing. This system offers a significant upgrade over manual systems, streamlining school schedules and improving …
Published in Journal of Control & Instrumentation · Vol. 16, Issue 2, 2025 · pp. 35–44 Read article
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Drug Utilisation and Cost Analysis in End-Stage Renal Disease Patients: A Prospective Observational Study
Abstract: Chronic Kidney Disease (CKD) is a condition in which the kidneys are damaged and unable to efficiently remove waste and excess fluid from the blood. Dialysis serves as a treatment for CKD by artificially carrying out the kidney’s filtering functions. This prospective observational cross-sectional study was conducted to evaluate drug utilization patterns, economic burden, and health-related quality of life (HRQoL) among patients with end-stage renal disease (ESRD) undergoing dialysis. Over …
Published in Research and Reviews: A Journal of Health Professions · Vol. 15, Issue 2, 2025 · pp. 1–12 Read article
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Timestamp Extraction and Log Classification Using Supervised Machine Learning: A Comparative Study
Abstract: In modern software systems, logs are vital for monitoring application behavior, diagnosing issues, and analyzing performance. Timestamps are especially important for sequencing events, identifying anomalies, and understanding system failures. However, detecting timestamps in logs is challenging due to inconsistent formatting across systems and the presence of timestamp-like strings in non-timestamp fields. Traditional rule-based methods often fail in such cases. This study proposes a supervised machine learning approach to accurately classify …
Published in Journal of Software Engineering Tools & Technology Trends · Vol. 12, Issue 3, 2025 · pp. 26–38 Read article