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622 articles for “potential treatments”
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IN SILICO SCREENING AND EVALUATION OF SOME METABOLITES FROM MOMORDICA CHARANTIA IN THE TREATMENT OF PEPTIC ULCERS
Abstract: Peptic ulcers are also called as or duodenal ulcers or gastric ulcers that are open sores generally develop in the lining of the stomach due to food and climatic factors. H. pylori infections are potentially the most dangerous and are linked to several diseases like diabetes, cancer, cardiovascular diseases, etc. In the present study, in silico screening and evaluation of some metabolites from Momordica charantia like Momorcharin, Momordicin, Metformin, Pioglitazone, …
Published in Research and Reviews : Journal of Computational Biology · Vol. 10, Issue 1, 2021 Read article
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The Unseen World Within: Decoding the Intricacies of Gut Microbiota and Its Impact on Human Health
Abstract: This comprehensive review delves into the multifaceted role of the gut microbiota in human health, elucidating its impact on diverse physiological processes, immune responses, and metabolic diseases. The intricate interplay of diet, genetics, and environmental factors is explored in shaping the composition and function of the gut microbiota, with consequential effects on conditions ranging from metabolic disorders to inflammatory bowel diseases and mental health. Therapeutic interventions, including probiotics, prebiotics, and …
Published in Research and Reviews: A Journal of Microbiology and Virology · Vol. 13, Issue 3, 2023 · pp. 12–21 Read article
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Computational Exploration of Bhrijraj-derived Phytochemicals as Potential Anti-inflammatory Agents: A Molecular Docking Study with Cyclooxygenase-II Complex
Abstract: The molecular docking analysis was meticulously conducted using state-of-the-art computational tools, notably Chimera and Python. These tools were employed to unravel the complex interactions between the identified phytochemicals from Bhrijraj and the target protein, COX-II. The 3D structures of the phytochemicals were prepared with precision using ChemSketch, ensuring accuracy in the subsequent molecular docking simulations. This rigorous approach enhances the reliability and validity of the findings. This research aims to …
Published in Research and Reviews : Journal of Computational Biology · Vol. 13, Issue 1, 2024 · pp. 31–37 Read article
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Glitches in the Implementation of Bioinformatics in Medical Settings: A Comprehensive Review
Abstract: Bioinformatics is a dynamic field at the intersection of biology, computer science, and information technology, offering new possibilities in medicine by enabling a deeper understanding of genomics, molecular biology, and personalized treatment approaches. Its integration into healthcare could greatly enhance diagnostics, enable tailored treatments for individuals, and facilitate the analysis of large biological datasets. However, despite its potential, several barriers impede its successful implementation in clinical settings. These include technical …
Published in Research & Reviews: A Journal of Bioinformatics · Vol. 11, Issue 3, 2024 · pp. 1–6 Read article
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Polymer Matrix-Based High-Performance Thermoplastic Composites for Automotive Applications: Design, Characterization, and Interface Behavior
Abstract: The study emphasizes the role of high-performance thermoplastic polymer matrices such as PEEK, PPS, and PA6, selected for their superior thermal stability, mechanical strength, and recyclability in automotive environments. The expanded usage of electric vehicles (EVs) and self-driving transportation creates a demand for advanced materials which are weight-conscious yet high in strength relative to their weight, impact-resistant yet still being environmentally friendly. This study aims to create and define fiber-reinforced …
Published in Journal of Polymer & Composites · Vol. 13, Issue 5, 2025 · pp. 216–237 Read article
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Molecular Dynamics and Therapeutic Architectures of Cannabinoid Receptors: A Comprehensive Review
Abstract: Expanding on these foundations, recent structural biology studies using cryo-electron microscopy have provided high-resolution insights into the conformational dynamics of CB₁ and CB₂ receptors. These findings have enabled a more precise understanding of ligand–receptor interactions, particularly how agonists, antagonists, and reverse agonists stabilize distinct receptor states. Such knowledge is critical for rational drug design, allowing researchers to selectively modulate downstream signaling pathways. For instance, CB₁ receptors primarily couple to Gi/o …
Published in International Journal of Cheminformatics · Vol. 4, Issue 1, 2026 · pp. 36–40 Read article
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Computational Identification of Antigenic Proteins and Epitopes in Hantavirus sp. for Drug Repurposing
Abstract: Hantavirus is an emerging virus that spreads from animals to humans and can cause serious illnesses like hantavirus pulmonary syndrome (HPS) and hemorrhagic fever with renal syndrome (HFRS). there are no FDA-approved treatments available for these diseases. This study explores in-silico drug repurposing as a strategy to identify potential therapeutic candidates. The physicochemical, secondary structure, antigenicity, and post-translational modification analysis of hantavirus proteins – specifically the glycoprotein precursor, N protein, …
Published in International Journal of Molecular Biotechnological Research · Vol. 3, Issue 1, 2025 · pp. 20–26 Read article
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Monkeypox Virus (MPXV): Epidemiology, Pathogenesis, and Control Strategies: Exploring the Recent Resurgence of Monkeypox, Its Transmission Dynamics, Clinical Manifestations, and Public Health Responses
Abstract: Monkeypox virus (MPXV) has re-emerged as a significant public health concern, with increasing cases reported worldwide. This zoonotic virus, primarily endemic to Central and West Africa, has demonstrated the potential for human-to-human transmission, leading to outbreaks in non-endemic regions. Unlike smallpox, which was eradicated through mass vaccination, monkeypox continues to persist due to the lack of widespread immunity and effective antiviral treatments. The resurgence of MPXV in recent years, particularly …
Published in International Journal of Virus Studies · Vol. 2, Issue 1, 2025 · pp. 29–34 Read article
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DESIGN AND FABRICATION OF EFFLUENT TREATMENT PLANT
Abstract: Effluent water treatment plant works by removing sludge and bacteria from wastewater before releasing them into river. Several river basins are closed due to the excessive growth in the agricultural area, semi urbanization as well as in the industrialization. The performance of wastewater treatment plants for the treatment of small waste also does not meet the required standards. Effluent Treatment Plant (ETP) mainly consists of treatment tanks, clarifier, filter press …
Published in Journal of Experimental & Applied Mechanics · Vol. 10, Issue 2, 2019 · pp. 31–35 Read article
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Bioremediation Potential: Discovering Naphthalene-Degrading Microbes in Iraqi Contaminated Soil
Abstract: A polycyclic aromatic hydrocarbon, napthalene is an environmental contaminant with a slow rate of disintegration. Biological treatment by microbes present in contaminated places is the most important of the several approaches applied to remove it from the environment. At depths of 5 to 10 cm, soil samples were collected from areas polluted by oil near the Al-Dora and Sheikh Omar refineries. Nutrient agar was cultured with 0.1 ml of each …
Published in International Journal of Pathogens · Vol. 1, Issue 2, 2024 · pp. 32–41 Read article
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A Review on Banana Fiber Reinforced Polymer Composites through Advanced Surface Treatments and Manufacturing Techniques
Abstract: In today's rapidly evolving world, heightened environmental concerns and stringent government regulations have spurred scientists and researchers to seek biodegradable and renewable alternatives to synthetic materials. Natural fibers, derived from resources like banana, jute, bagasse, and sisal, offer distinct advantages such as low density, comparable strength, non-toxicity, cost-effectiveness, and minimal waste disposal issues over synthetic counterparts. Extensive research has explored the potential applications of these natural fibers, with banana fibers …
Published in Trends in Mechanical Engineering & Technology · Vol. 14, Issue 3, 2024 Read article
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Digital Health Interventions in Cardiovascular Pharmacology: A Review
Abstract: Cardiovascular diseases (CVDs) represent a formidable global health challenge, demanding innovative strategies for timely detection, effective management, and continuous monitoring. This study delves into the transformative potential of digital health interventions (DHIs), such as telemedicine and remote monitoring, in reshaping cardiovascular care paradigms. DHIs offer unparalleled accessibility, convenience, and personalized attention, thereby promising to revolutionize traditional approaches to cardiovascular health management. One of the foremost advantages of DHIs lies in …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 14, Issue 2, 2024 · pp. 1–5 Read article
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FDA Drug Approvals 2024: A Comprehensive Review
Abstract: The year 2024 has been pivotal for the pharmaceutical industry, with the U.S. Food and Drug Administration (FDA) granting approval to a diverse array of new drugs. These approvals highlight significant strides in therapeutic innovation, targeting a spectrum of diseases from rare genetic disorders to prevalent chronic conditions. This article provides a detailed examination of the FDA-approved drugs of 2024, focusing on their therapeutic indications, mechanisms of action, and the …
Published in Research & Reviews: A Journal of Drug Formulation, Development and Production · Vol. 12, Issue 1, 2025 · pp. 28–46 Read article
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Effectiveness of Habb-e-Suranjan and Roghan-e-Farfiyun in the Management of Waja-ul-Rukba (Knee Pain): A Review
Abstract: Introduction: Knee osteoarthritis is a painful condition that represents the degeneration of the cartilage and osteophyte formation in the knee joint, which affects millions of people worldwide. According to the Unani claimed text, accumulation of “madda” (substance) in joints, which is neither absorbed nor expelled, is due to the absence of Quawwat-e-Jazibah (power of absorption) and Quawwat-e-dafia (power of expulsion). Unani medicine presents a promising approach for managing knee osteoarthritis …
Published in Research & Reviews : A Journal of Unani, Siddha and Homeopathy · Vol. 12, Issue 2, 2025 · pp. 7–12 Read article
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Critical Review on Photocatalytic Polymer Nanocomposites for Indoor Air Purification in Hotels
Abstract: The indoor air quality has become a key measure of health, comfort, and customer satisfaction of a hospitality setting. The challenges that continually affect hotels especially because of volatile organic compounds (VOCs), particulate matter, and microbial pollutants that are present in cleaning agents, furnishing, and human activity. In this regard, the photocatalytic polymer nanocomposites are one of the sustainable and efficient means of purifying indoor air. These materials combine photocatalysts …
Published in Journal of Polymer & Composites · Vol. 14, Issue 2, 2026 · pp. 527–541 Read article
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Design and Detailing of a Waste Water Treatment Plant for a Small Community
Abstract: The water supplied to a community receives a range of chemical substances and microbial flora during its use such that the waste water acquires a polluting potential and becomes a health and environmental hazard. Communicable diseases of the intestinal tract such as; cholera, typhoid, dysenteries and water borne diseases like infectious hepatitis etc. can be spread from uncontrolled disposal of waste water and therefore, prevention of communicable diseases and protecting …
Published in Journal of Water Resource Engineering and Management · Vol. 1, Issue 3, 2014 · pp. 1–12 Read article
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Neurobehavioral Disorders: Mapping Biomarkers for Preclusion
Abstract: Neurobehavioral disorders include Attention Deficit Hyperactivity Disorder (ADHD), Autism Spectrum Disorder (ASD), Schizophrenia, Obsessive Compulsive Disorder (OCD)and Intellectual Disability (ID) as present serious problems for individuals as well as the community. These illnesses are characterized by a wide range of complex symptoms, which makes early assessment, diagnosis, and treatment challenging. However, recent developments in technology and neuroscience have given rise to fresh understandings of the fundamental processes and potential biomarkers …
Published in Research and Reviews: A Journal of Neuroscience · Vol. 13, Issue 2, 2023 · pp. 8–22 Read article
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Role of Herbal Medicines in the Management of Diabetes
Abstract: Diabetes mellitus is a condition marked by elevated blood sugar levels, alterations in the metabolism of lipids, carbohydrates, and proteins, and over time, it can lead to complications affecting the eyes, kidneys, cardiovascular system, and neurological functions Many plants from throughout the world have been investigated for their potential to prevent diabetes. This review article aims to highlight some key medicinal plants with blood sugar-lowering effects supported by credible clinical …
Published in Research & Reviews: A Journal of Pharmacognosy · Vol. 13, Issue 1, 2026 · pp. 29–38 Read article
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Evaluation of Antioxidant and Cytotoxic activities of Mycelia Biomass and Culture broth of three Edible Mushrooms, Morchella conica, Hericium erinaceus and Pleurotus florida Grown in Submerged Culture
Abstract: Mycelia biomass of three edible mushrooms namely, Morchella conica, Pleurotus florida and Hericium erinaceus were grown as submerged culture in potato dextrose broth supplemented with yeast extract, potassium dihydrogen orthophosphate and magnesium sulphate. The mycelia biomass was extracted with 70% ethanol and culture broth with ethyl acetate. The solvents were evaporated to dryness at low temperature using a rotary vacuum evaporator and the residues thus obtained were used for the …
Published in International Journal of Fungi · Vol. 1, Issue 1, 2024 · pp. 37–50 Read article
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Comprehensive Review on Postoperative Nausea and Vomiting Following General Anesthesia
Abstract: Postoperative nausea and vomiting, often known as PONV, is a common and uncomfortable consequence that occurs after general anesthesia. Patients of all ages are susceptible to experiencing this condition. Even though there have been advances in anaesthesia procedures and treatments, postoperative nausea and vomiting (PONV) continues to be a serious concern since it has the potential to cause patients to experience discomfort, delay their recovery, extend their hospital stays, and …
Published in International Journal of Advance in Molecular Engineering · Vol. 2, Issue 2, 2024 · pp. 20–26 Read article